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1Osteoblastic and anti-osteoclastic activities of strontium-substituted silicocarnotite ceramics: In vitro and in vivo studies显示文摘Osteoporosis bone defect is a refractory orthopaedic disease which characterized by impaired bone quality and bone regeneration capacity.Current therapies,including antiosteoporosis drugs and artificial bone grafts,are not always satisfactory.Herein,a strontium-substituted calcium phosphate silicate bioactive ceramic(Sr-CPS)was fabricated.In the present study,the extracts of Sr-CPS were prepared for in vitro study and Sr-CPS scaffolds were used for in vivo study.The cytocompatibility,osteogenic and osteoclastogenic properties of Sr-CPS extracts were characterized in comparison to CPS.Molecular mechanisms were also evaluated by Western blot.Sr-CPS extracts were found to promote osteogenesis by upregulating Wnt/β-catenin signal pathways and inhibit osteoclastogenesis through downregulating NF-κB signal pathway.In vivo,micro-CT,histological and histomorphometric observation were conducted after 8 weeks of implantation to evaluate the bone formation using calvarial defects model in ovariectomized rats.Compared with CPS,Sr-CPS significantly promoted critical sized ovariectomy(OVX)calvarial defects healing.Among all the samples,Sr-10 showed the best performance due to a perfect match of bone formation and scaffold degradation rates.Overall,the present study demonstrated that Sr-CPS ceramic can dually modulate both bone formation and resorption,which might be a promising candidate for the reconstruction of osteoporotic bone defect.Junkai Zeng Jingshu Guo Zhenyu Sun Fanyan Deng Congqin Ning Youzhuan Xie 2020Bioactive Materials2020,5,3:9
2Effect of current polarity on electrical sliding wear behavior of Cu-WS_2-graphite-WS_2 nanotube composites in air and vacuum conditions显示文摘In this paper Cu-WS2-graphite-WS2nanotube composites were fabricated by powder metallurgy hot pressing method.The effect of current polarity on the wear rates and contact voltage drops of the composites were investigated using a brush-on-slip ring tribometer rubbing against Cu-5 wt.%Ag alloy ring in air and vacuum,respectively.The worn surfaces of the composites were analyzed by scanning electron microscopy(SEM)and X-ray photoelectron spectroscopy(XPS).Surface profile curves of the worn tracks were measured using the surface profiler.The results demonstrated that the current polarity has a significant effect on the wear rates and contact voltage drops of the composites in both air and vacuum conditions.Positive brush possesses a higher wear rate compared with the negative brush in the air atmosphere since the electrical field direction activates oxidation at the positive brush surface while inhibits oxidation at the negative brush surface.Except for the regular wear losses,the combined effect of molten metal bridge erosion and arc erosion cause the positive brush to lose extra material and the negative brush to gain extra material,so the positive brush shows a higher wear rate in the vacuum condition.The contact voltage drop of the positive brush is lower than that of the negative brush in the air atmosphere,but contrarily,the positive brush shows a higher contact voltage drop in the vacuum condition.QIAN Gang FENG Yi CHEN FanYan LIU WenHong ZHANG XueBin LIU YanFang 2013Science China(Technological Sciences)2013,56,11:5
3The Termination and Aftermath of the Lomagundi -Jatuli Carbon Isotope Excursions in the Paleoproterozoic Hutuo Group, North China显示文摘The Lomagundi-Jatuli Event(LJE) is one of the largest and earliest positive carbon isotope excursions preserving δ^(13)C_(carb) values between +5 and +16‰ in Paleoproterozoic carbonates worldwide. However, the duration, amplitude and patterns of these excursions remain poorly constrained. The 2.14–1.83 Ga Hutuo Group in the North China Craton is a >10 km thick volcano-sedimentary sequence, including >5 km thick well-preserved carbonates that were deposited in supra-tidal to sub-tidal environments. C-O isotopic and elemental analyses of 152 least altered samples of the carbonates revealed a three-stage δ^(13)C evolution. It began with an exclusively positive δ^(13)C_(carb)(+1.3 to + 3.4‰) stage in the ~2.1 Ga carbonate in the Dashiling and Qingshicun Formations, followed by a transition from positive values to oscillating positive and negative values in ~3 000 m thick carbonates of the Wenshan, Hebiancun, Jianancun, and Daguandong Formations, and end with exclusively negative δ^(13)C_(carb) values preserved in > 500 m thick dolostones of the Huaiyincun and Beidaxing Formations. It appears that much of the LJE, particularly those extremely positive δ^(13)C_(carb) signals, was not recorded in the Hutuo carbonates. The exclusively positive δ^(13)C_(carb) values(+1.3 to + 3.4‰) preserved in the lower formations likely correspond to the end of the LJE, whereas the subsequent two stages reflect the aftermath of the LJE and the onset of Shunga-Francevillian event(SFE). The present data point to an increased influence of oxygen on the carbon cycle from the Doucun to the Dongye Subgroups and demonstrate that the termination of the LJE in the North China Craton is nearly simultaneous with those in Fennoscandia and South Africa.Zhenbing She Fanyan Yang Wei Liu Luhua Xie Yusheng Wan Chao Li Dominic Papineau 2016Journal of Earth Science2016,27,2:4
4Advanced protein adsorption properties of a novel silicate-based bioceramic: A proteomic analysis显示文摘Silicate bioceramics have been shown to possess excellent cytocompatibility and osteogenic activity,but the exact mechanism is still unclear.Protein adsorption is the first event taking place at the biomaterial-tissue interface,which is vital to the subsequent cellular behavior and further influence the biomaterial-tissue interaction.In this work,the protein adsorption behavior of a novel CPS bioceramic was evaluated using the proteomics technology.The results showed that CPS adsorbed more amount and types of serum proteins than HA.FN1 and IGF1 proteins selected from proteomics results were validated by Western-blot experiment.Pathway analysis also revealed mechanistic insights how these absorbed proteins by CPS help mediate cell adhesion and promotes osteogenic activity.Firstly,the dramatically enhanced adsorption of FN1 could greatly promote cell adhesion and growth.Secondly,IGF1 was uniquely adsorbed on CPS bioceramic and IGF1 could activate Rap1 signaling pathway to promote cell adhesion.Thirdly,the increased adsorption of FN1,IGF1 and COL1A2 proteins on CPS explains its better ability on bone regeneration than HA.Fourthly,the increased adsorption of IGF1,CHAD,COL2A1 and THBS4 proteins on CPS explains its ability on cartilage formation.Lastly,the increased adsorption of immunological related proteins on CPS may also play a positive role in bone regeneration.In addition,CPS had a much better cell adhesion ability than HA,proving that more adsorbed proteins really had a positive effect on cell behavior.The more adsorbed proteins on CPS than HA might indicated a better bone regeneration rate at early stage of implantation.Fanyan Deng Wanyin Zhai Yue Yin Chao Peng Congqin Ning 2021Bioactive Materials2021,6,1:2
5Comparative first-principles study of elastic constants of covalent and ionic materials with LDA,GGA,and meta-GGA functionals and the prediction of mechanical hardness显示文摘Accurate prediction of single-crystal elastic constants is critical for materials design and for understanding phase transition and elastic interactions in materials.In this work,the accuracy of elastic constants calculated with three density functional approximations has been compared,including the local density approximation(LDA),the generalized gradient approximation(GGA),and the recently developed strongly constrained and appropriately normed(SCAN)meta-GGA.The results show that SCAN and PBE describe elastic constants better than LDA.The strong correlation between the mechanical hardness and the stiffness of the softest eigenmode(SSE)has been given for above three density functionals.The correlation is capable of predicting accurately the hardness of covalent,ionic,and mixed covalent-ionic crystals,and providing us a convenient indicator for the discovery of hard or superhard materials.XING WanDong MENG FanYan NING JinLiang SUN JianWei YU Rong 2021Science China(Technological Sciences)2021,64,12:2
6Reduced graphene oxide supported palladium–silver bimetallic nanoparticles for ethanol electro-oxidation in alkaline media显示文摘Jinping Liu Haihui Zhou Qianqian Wang Fanyan Zeng Yafei Kuang 2012Journal of Materials Science2012,,5:2
7Patterns and drivers of CH_(4) concentration and diffusive flux from a temperate river–reservoir system in North China显示文摘Freshwater reservoirs are regarded as an important anthropogenic source of methane(CH_(4))emissions. The temporal and spatial variability of CH_(4) emissions from different reservoirs results in uncertainty in the estimation of the global CH_(4) budget. In this study, surface water CH_(4) concentrations were measured and diffusive CH_(4) fluxes were estimated via a thin boundary layer model in a temperate river–reservoir system in North China, using spatial(33 sites) and temporal(four seasons) monitoring;the system has experienced intensive aquaculture disturbance. Our results indicated that the dissolved CH_(4) concentration in the reservoir ranged from 0.07 to 0.58 μmol/L, with an annual average of 0.13 ± 0.10 μmol/L, and the diffusive CH_(4) flux across the water–air interface ranged from 0.66 to 3.61 μmol/(m^(2)·hr),with an annual average of 1.67 ± 0.75 μmol/(m^(2)·hr). During the study period, the dissolved CH_(4) concentration was supersaturated and was a net source of atmospheric CH_(4) . Notably,CH_(4) concentration and diffusive flux portrayed large temporal and spatial heterogeneity.The river inflow zone was determined to be a hotspot for CH_(4) emissions, and its flux was significantly higher than that of the tributary and main basin;the CH_(4) flux in autumn was greater than that in other seasons. We also deduced that the CH_(4) concentration/diffusive flux was co-regulated mainly by water temperature, water depth, and water productivity(Chla, trophic status). Our results highlight the importance of considering the spatiotemporal variability of diffusive CH_(4) flux from temperate reservoirs to estimate the CH_(4) budget at regional and global scales.Fanyan Yang Jicheng Zhong Shaoming Wang Xiaokang Hu Hongwei Wang Mengyao Tang Min Zhang Chuanzhe Sun Lei Zhang 2022Journal of Environmental Sciences2022,34,6:1
8Formation of better catalytically active titanium species in Ti-MCM-41 by vapor-phase silylation显示文摘Lin Kaifeng Wang Lifeng Meng Fanyan 2005Journal of Catalysis2005,235,:1
9There-searchonassociationruleminingmethodbasedondatacluster显示文摘WangQingyi FanYan ZouXiang 2000Journal of Nan Jing University2000,36,11:1
10Improvement of mechanical properties of stainless maraging steel laser weldments by post-weld ageing treatments显示文摘Jian An Fanyan Meng Xiaoxia Lv Haiyuan Liu Xiaoxi Gao Yuanbo Wang You Lu 2012Materials and Design2012,,:1
11Reduced graphene oxide supported palladium–silver bimetallic nanoparticles for ethanol electro-oxidation in alkaline media显示文摘Jinping Liu Haihui Zhou Qianqian Wang Fanyan Zeng Yafei Kuang 2012Journal of Materials Science2012,,5:1
12Bi and S Co-doping g-C_(3)N_(4)to Enhance Internal Electric Field for Robust Photocatalytic Degradation and H_(2) Production显示文摘By adjusting the type and proportion of doping elements in the g-C_(3)N_(4)-based photocatalyst,the internal electric field(IEF)strength of the semiconductor can be regulated.This can effectively enhance the driving force of charge separation in the photocatalytic process.It is found that the introduction of appropriate concentration of Bi and S into the skeleton structure of g-C_(3)N_(4)can achieve efficient degradation of tetracycline(TC)and other pollutants in the liquid environment and excellent photocatalytic H_(2)evolution performance(1139μmol·L^(-1)·h^(-1)).Since the prepared samples have similar crystal structures,the relative strength of IEF can be calculated.It can be used as the basis for adjusting the IEF strength of g-C_(3)N_(4)-based semiconductor by element doping.In addition,the Bi and S co-doped g-C_(3)N_(4)samples after solvothermal reflux show good chemical stability and can reduce the nanostructure defects caused by co-doping of heteroatoms,thus it provides a novel solution for the construction of g-C_(3)N_(4)-based dual-function photocatalyst with high activity and stability.Yan Hu Xibao Li Weiwei Wang Fang Deng Lu Han Xiaoming Gao Zhijun Feng Zhi Chen Juntong Huang Fanyan Zeng Fan Dong 2022Chinese Journal of Structural Chemistry2022,41,6:1
13The Expression of ppGalNAc-T2 in Different Tumor Cells and the Effect of Radiation显示文摘FANYan CHENKe-Ping HUJia XUAi-Hua 2003生物化学与生物物理学报2003,35,11:0
14The Impact of The Bible on the English Language显示文摘The Bible is called a classic of Western civilization.Its doctrines and ideas have laid the foundation for Western culture and thought,but also the source of Western languages,producing important influence on the English language.The English language cultures are closely related to The Bible,and even can be said that The Bible is one of the cultural origins of the English language.MA Shunshun MENG Fanyan 2022US-China Foreign Language2022,20,3:0
15Decoration of carbon encapsulated nitrogen-rich MoxN with few-layered MoSe2 nanosheets for high-performance sodium-ion storage显示文摘Transition metal nitrides have become the focus of research in sodium ion batteries(SIBs)due to their unique metal properties and high theoretical capacity.However,the low actual capacity is still the main bottleneck for their application.Herein,using Mo-aniline frameworks as precursors,the carbon encapsulated nitrogen-rich Mo_(x)N is decorated by few-layered MoSe_(2) nanosheets(MoSe_(2)@Mo_(x)N/C-I)after the facile calcinating,selenizing,and nitriding.The carbon encapsulation can effectively strengthen the structural stability of Mo_(x)N.The nitrogen-rich Mo_(x)N and decoration of few-layered MoSe_(2) can create rich heterointerfaces and extra active sites for rapid sodium-ion storage,thus promoting reaction kinetics and improving actual capacity.The MoSe_(2)@Mo_(x)N/C-I as an anode achieves a large reversible capacity of 522.8 mAh g^(-1)at 0.1 A g^(-1),and 254.3 mAh g^(-1)capacity is obtained after 6000 cycles at 5.0 A g^(-1),showing signally improved sodium-ion storage properties.The storage mechanisms and kinetic behaviors are described systematically via the advanced testing techniques and density functional theory(DFT)calculations.It is found that the nitrogen-rich Mo_(x)N as the substrate is the basis of long cycling stability,and the few-layered MoSe_(2) are the key to improving actual capacity.This work indicates that the decoration of few-layered selenides has a broad application prospect in high-performance metal-ion batteries.Tao Lu Baoquan Liu Fanyan Zeng Guo Cheng Shile Chu Meilan Xie Zhi Chen Zhaohui Hou 2022Journal of Energy Chemistry2022,31,11:0
16Effect of Nozzle Inclination Angle on Fuel-Air Mixing and Combustion in a Heavy Fuel Engine显示文摘Heavy-fuel engines are widely used in UAVs(Unmanned Autonomous Vehicles)because of their reliability and high-power density.In this study,a combustion model for an in-cylinder direct injection engine has been imple-mented using the AVL FIRE software.The effects of the angle of nozzle inclination on fuel evaporation,mixture distribution,and combustion in the engine cylinder have been systematically studied at 5500 r/min and consider-ing full load cruise conditions.According to the results,as the angle of nozzle inclination increases,the maximum combustion explosion pressure in the cylinderfirst increases and then it decreases.When the angle of nozzle incli-nation is less than 45°,the quality of the mixture in the cylinder and the combustion performance can be improved by increasing the angle.When the angle of nozzle inclination is greater than 45°,however,the mixture unevenness increases slightly with the angle,leading to a deterioration of the combustion performances.When the angle of nozzle inclination is between 35°and 55°,the overall combustion performance of the engine is rela-tively good.When the angle of nozzle inclination is 45°,the combustion chamber’s geometry and the cylinder’s airflow are well matched with the fuel spray,and the mixture quality is the best.Compared with 25°,the peak heat release rate increases by 20%,and the maximum combustion burst pressure increases by 5.5%.Zhigang Wang Bin Zheng Peidong Zhao Baoli Wang Fanyan Meng Wenke Xu Jian Meng 2024Fluid Dynamics & Materials Processing2024,20,2:0
17Prediction of stable high-pressure structures of tantalum nitride TaN2显示文摘Structure searches based on a combination of first-principles calculations and a particle swarm optimization technique unravel two new stable high-pressure structures(C2/m and Cmce) for Ta N2. The structural features, mechanical properties, formation enthalpies, electronic structure, and phase diagram of Ta N2 are fully investigated. Being mechanically and dynamically stable, the two phases could be made metastable experimentally at ambient conditions.Wandong Xing Zijie Wei Rong Yu Fanyan Meng 2019Journal of Materials Science & Technology2019,35,10:0
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