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| 1 | Maximum standardized uptake value on PET/CT in preoperative assessment of lymph node metastasis from thoracic esophageal squamous cell carcinoma显示文摘The presence of lymph node metastasis is an important prognostic factor for patients with esophageal cancer.Accurate assessment of lymph nodes in thoracic esophageal carcinoma is essential for selecting appropriate treatment and forecasting disease progression.Positron emission tomography combined with computed tomography(PET/CT)is becoming an important tool in the workup of esophageal carcinoma.Here,we evaluated the effectiveness of the maximum standardized uptake value(SUVmax)in assessing lymph node metastasis in esophageal squamous cell carcinoma(ESCC)prior to surgery.Fifty-nine surgical patients with pathologically confirmed thoracic ESCC were retrospectively studied.These patients underwent radical esophagectomy with pathologic evaluation of lymph nodes.They all had18F-FDG PET/CT scans in their preoperative staging procedures.None had a prior history of cancer.The pathologic status and PET/CT SUVmax of lymph nodes were collected to calculate the receiver operating characteristic(ROC)curve and to determine the best cutoff value of the PET/CT SUVmax to distinguish benign from malignant lymph nodes.Lymph node data from 27 others were used for the validation.A total of 323 lymph nodes including 39 metastatic lymph nodes were evaluated in the training cohort,and 117lymph nodes including 32 metastatic lymph nodes were evaluated in the validation cohort.The cutoff point of the SUVmax for lymph nodes was 4.1,as calculated by ROC curve(sensitivity,80%;specificity,92%;accuracy,90%).When this cutoff value was applied to the validation cohort,a sensitivity,a specificity,and an accuracy of 81%,88%,and 86%,respectively,were obtained.These results suggest that the SUVmax of lymph nodes predicts malignancy.Indeed,when an SUVmax of 4.1 was used instead of 2.5,FDG-PET/CT was more accurate in assessing nodal metastasis. | Amos JM Ela Bella Ya-Rui Zhang Wei Fan Kong-Jia Luo Tie-Hua Rong Peng Lin Hong Yang Jian-Hua Fu | 2014 | Chinese Journal of Cancer2014，33，4： | 3 |
| 2 | Structural elucidation of a neutral fucogalactan from the mycelium of Coprinus comatus显示文摘 | FAN JM ZHANG JS TANG QJ | 2006 | Carbohydr Res2006，341，9： | 1 |
| 3 | Experimental study on antiatherosele rotic treatmenlby PGE1 combined with vitamine and estradiol显示文摘 | Qiu JM Gao YX Fan YC | 1995 | Chin Med J Engl1995，108，1： | 1 |
| 4 | Transforming growth factor-β regulates tubular epithelial myofibroblast transdifferentiation in vitro显示文摘 | Fan JM Ng YY Hill PA | 1999 | Kidney Int1999，56，12： | 1 |
| 5 | Interleukin-1 induces tubular epithelial-myofibroblast transdifferentiation throug a transforming growth factor-beta1-dependent mechanism in vitro显示文摘 | Fan JM Huang XR NG YY | 2001 | J Kidney Dis2001，37，4： | 1 |
| 6 | Bioavailability and phar- macokinetics of sorafenib suspension, nanoparticles and nanomatrix for oral administration to rat 显示文摘 | Wang XQ Fan JM Liu YO | 2011 | Int J Pharm2011，419，12： | 1 |
| 7 | Interleukin-linduced tu- bular epithelial- myofibroblast transdifferentiation through a transforming growth factor-β- dependent mechanism in vitro 显示文摘 | Fan JM Huang XR Ng YY | 2001 | Am J Kidney Disease2001，38，： | 1 |
| 8 | Glomerular epithelial-myofibroblast transdifferentiation in the evolution of glomerular crescent formation 显示文摘 | Ng YY Fan JM Mu W | 1999 | Nephrol Dial Transplant1999，14，12： | 1 |
| 9 | Effects of hepatocyte growth factor on TGF-betal triggered tubular epithelial-myofibroblast transdiffer-entiation by CTGF in vitro 显示文摘 | Zhong H Fan JM Li Z | 2005 | Sichuan Da Xue Xue Bao Yi Xue Ban2005，36，5： | 1 |
| 10 | TGF-β1 regulates tubular epithelial myofibroblast transdifferentiation (TEMT) in vitro显示文摘 | FAN JM ATKINS RC LAN HY | 1998 | Nephroogy1998，4，： | 1 |
| 11 | Transforming growth factor-β regulats tubular epithelial-myofibroblast transdifferentiation in vitro显示文摘 | Fan JM Ng YY Hill PA | 1999 | Kidney Int1999，56，： | 1 |
| 12 | Gestationa显示文摘 | Fan JM Chen XQ J eta | 2009 | Neuroscience2009，159，4： | 1 |
| 13 | Isolation and functional charac-terization of the actin binding region in the tight junction protein ZO -1显示文摘 | Fanning AS Ma TY Anderson JM | 2002 | FasebJ2002，16，13： | 1 |
| 14 | The structure and regulation of tight junctions显示文摘 | Anderson JM Balda MS Fanning AS | 1993 | Curt Opin Cell Biol1993，5，5： | 1 |
| 15 | Rehabilitation therapy and outcomes in acute respiratory failure: an observational pi- lot project显示文摘 | Zanni JM Korupolu R Fan E | 2010 | J Crit Care2010，25，2： | 1 |
| 16 | Transforming growth factor-β regulates tubular epithelial myofibroblast transdifferentiation in vitro显示文摘 | Fan JM Ng YY Hill PA | 1999 | Kidney Int1999，56，12： | 1 |
| 17 | Transmembrane proteins in the tight junction baxa'ier 显示文摘 | Fanning AS Mitic LL Anderson JM | 1999 | J Am Soe Nephrol1999，10，6： | 1 |
| 18 | Transforming growth factor-β regulates tubular epithelial-myofibroblast transdifferentiation in vitro 显示文摘 | Fan JM Ng YY Hill PA | 1999 | Kidney Int1999，56，4： | 1 |
| 19 | Transforming growth factor-beta regulates tubular epithelial myofibroblast transdifferentiation in vitro 显示文摘 | Fan JM Ng YY Hill P et ol | 1999 | Kidney Int1999，56，4： | 1 |
| 20 | Transforming growth factor-beta regulates tubular epithelial-myofibroblast transdifferentiation in vitro 显示文摘 | Fan JM Ng YY Hill PA | 1999 | Kidney Int1999，56，4： | 1 |
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