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| 1 | Partially hydrolyzed guar gum in pediatric functional abdominal pain显示文摘AIM:To assess the effects of partially hydrolyzed guar gum(PHGG) diet supplement in pediatric chronic abdominal pain(CAP) and irritable bowel syndrome(IBS).METHODS:A randomized,double-blind pilot study was performed in sixty children(8-16 years) with functional bowel disorders,such as CAP or IBS,diagnosed according to Rome Ⅲ criteria.All patients underwent ultrasound,blood and stool examinations to rule out any organic disease.Patients were allocated to receive PHGG at dosage of 5 g/d(n = 30) or placebo(fruitjuice n = 30) for 4 wk.The evaluation of the efficacy of fiber supplement included IBS symptom severity score(Birmingham IBS Questionnaire),severity of abdominal pain(Wong-Baker Face Pain Rating Score) and bowel habit(Bristol Stool Scale).Symptom scores were completed at 2,4,and 8 wk.The change from baseline in the symptom severity scale at the end of treatment and at 4 wk follow-up after treatment was the primary endpoint.The secondary endpoint was to evaluate compliance to supplementation with the PHGG in the pediatric population.Differences within groups during the treatment period and follow-up were evaluated by the Wilcoxon signed-rank test.RESULTS:The results of the study were assessed considering some variables,such as frequency and intensity of symptoms with modifications of the bowel habit.Both groups were balanced for baseline characteristics and all patients completed the study.Group A(PHGG group) presented a higher level of efficacy compared to group B(control group),(43% vs 5%,P = 0.025) in reducing clinical symptoms with modification of Birmingham IBS score(median 0 ± 1 vs 4 ± 1,P = 0.025),in intensity of CAP assessed with the Wong-Baker Face Pain Rating Score and in normalization of bowel habit evaluated with the Bristol Stool Scale(40% vs 13.3%,P = 0.025).In IBS subgroups,statistical analysis shown a tendency toward normalization of bowel movements,but there was no difference in the prevalence of improvement in two bowel habit subsets.PHGG was therefore better tolerated without any adverse effects.CONCLUSION:Although the cause of pediatric functional gastrointestinal disorders is not known,the results show that complementary therapy with PHGG may have beneficial effects on symptom control. | Claudio Romano Donatella Comito Annalisa Famiani Sabrina Calamarà Italia Loddo | 2013 | World Journal of Gastroenterology2013，19，2： | 3 |
| 2 | Diurnal and Seasonal Changes in Photosynthetic Characteristics in Different Olive (Olea europaea L) Cultivars显示文摘 | Proietti P Famiani F | 2002 | Photosynthetica2002，40，2： | 1 |
| 3 | Effect of CPPU treatment on fruit anatomical structure and quality in Actinidia deliciosa 显示文摘 | Antognozzi E Famiani F Proietti P | 1997 | Acta Hort1997，444，： | 1 |
| 4 | Frost re-sistance of some olive cultivars during the winter显示文摘 | Antognozzi E Famiani F Proietti P | 1994 | Acta Horticulturae1994，356，： | 1 |
| 5 | Increase of ascorbic acid content and mutrifional quality in spinach leaves during physiological acclimation to low temperature显示文摘 | PROIETTI S MOSCATELLO S FAMIANI F | 2009 | Plant Physiology and Biochemistry2009，47，8： | 1 |
| 6 | Influence of CPPU on carbohydrate accumulation and metabolism in fruits of Actinidia deliciosa (A. Chev.)显示文摘 | E. Antognozzi A. Battistelli F. Famiani S. Moscatello F. Stanica A. Tombesi | 1996 | Scientia Horticulturae1996，，1： | 1 |
| 7 | Effect of leaf excision time and age, BA concentration and dark treatment on in vitro shoot regeneration of M26 apple rootstock 显示文摘 | Famiani F Ferradini N Staffolani P -Standardi A | 1994 | J Hort Sci1994，69，4： | 1 |
| 8 | Influence of growth regulators and light on in vitro shoot regeneration in M26 apple rootstock 显示文摘 | Ferradini N Famiani F Proietti P | 1996 | J of Hort Sci1996，71，： | 1 |
| 9 | Effect of different leaf-to-fruit ratios on photosynthesis and fruit growth in olive (Olea europaea L) 显示文摘 | Prpietti P Nasini L Famiani F | 2006 | Photosynthetica2006，44，2： | 1 |
| 10 | Yield affects quali- tative kiwifruit characteristics and dry matter content may be an indicator of both quality and storability 显示文摘 | Famiani F Baldicchi A Farinelli D | 2012 | Scientia Horti- cuhurae2012，146，： | 1 |
| 11 | Influence of CPPU on carbohydrate accumulation and metabolism in fruits of Actinidia deliciosa(A Chev)显示文摘 | Antognozzi E Battistelli A Famiani F | 1996 | Sci Hortic1996，65，1： | 1 |
| 12 | Influence of CPPU on car- bohydrate accumulation显示文摘 | Antognozzi E Battistelli A Famiani F | 1996 | Scientia Horticuhurae1996，65，： | 1 |
| 13 | In vitro regeneration of different Actinidiaspecies 显示文摘 | FAMIANI F FERRADINI N STANDARDI A | 1997 | Acta - Horticulturae1997，444，： | 1 |
| 14 | Sucrose synthase dominates carbohydrate metabolism and relative growth rate in growing kiwifruit (Actinidia deliciosa,cv Hayward) 显示文摘 | Moscatello S Famiani F Proietti S | 2011 | Scientia Horticulturae2011，128，3： | 1 |
| 15 | Indeterminate colitis: adistinctive clinical pattern of inflammatory bowel disease inchildren显示文摘 | Romano C Famiani A Gallizzi R | 2008 | Pediatrics2008，122，6： | 1 |
| 16 | Increase of ascorbic acid content and nutritional quality in spinach leaves during physiological acclimation to low temperature 显示文摘 | Proietti S Moscatello S Famiani F | 2009 | Plant Physiology and Biochemistry2009，47，8： | 1 |
| 17 | Oral beclo- methasone dipropionate in pediatric active ulcerative colitis: a comparison trial with mesalazine显示文摘 | ROMANO C FAMIANI A COMITO D | 2010 | J Pediatr Gastroen- terol Nutr2010，50，4： | 1 |
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