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| 1 | Outcome of 1355 consecutive transabdominal chorionic villus samplings in 1351 patients显示文摘Background The true risk of choronic villus sampling (C VS) is poorly defined. The objective of this study was to review the clinical o utcome of transabdominal CVS performed in a university teaching unit, with an em phasis on the complication rate. Methods A comprehensive audit database was maintained for 1351 pregnant women, including 17 sets of twin pregnancies, who had a CVS. Details a nd outcome of all CVSs made in the unit between May 1996 and May 2004 were revie wed. All CVSs were performed by one of 5 operators using the identical techniqu es. Results All procedures were performed transabdominally. A tota l of 1355 CVSs were performed because there were 4 dichorionic twin pregnancies which required 2 punctures. The mean gestation at CVS was (11.8±0.7) weeks, and 97.3% of the procedures were performed between 11 and 13 completed weeks. The majority (96.2%) required only 1 puncture to achieve correct needle placeme nt. The procedure failed to obtain an adequate sample in 4 subjects (0.30%). A total of 1351 chromosomal studies were requested and there was 1 case (0.07%) of culture failure. The results of chromosomal studies were available within 1 4 days in 36.7% of the cases and within 21 days in 94.0%. Overall, 77 chromos omal abnormalities (5.7%) and 5 cases of thalassemia major were detected. Preg nancy outcome was unknown in only 13 singleton subjects (0.96%). In the remain ing 1355 fetuses, there were 76 pregnancy terminations (5.56%), 10 fetal losses with obvious obstetric causes (0.73%), and 21 potentially procedure-relat ed fetal losses (1.54%). In the last group, the majority had one or more co-e xisting obstetric complications. The background fetal loss rate for pregnancies at similar gestational age in the unit was about 0.8%. Therefore, the procedu re-related fetal loss rate was estimated to be at the maximum of 0.74%. Conclusions In experienced hands, first trimester transabdomina l CVS is an accurate and safe invasive prenatal diagnostic procedure. It should be one of the treatment options available to pregnant women who require prenata l genetic diagnosis. | LAU Tze Kin LEUNG Tak Yeung FUNG Tak Yuen Daljit S SAHOTA LEUNG Tse Ngong | 2005 | Chinese Medical Journal2005,,20: | 8 |
| 2 | Practice of breast self-examination among high risk Chinese women in Hong Kong显示文摘The incidence of breast cancer in Hong Kong is increasing and breast self examination (BSE) as a screening tool is becoming more popular, especially among first degree relatives (FDR) of breast cancer victims BSE may be more applicable to Chinese women as their breast size is smaller This study explores the BSE practice in this group of women Methods A cross sectional study was conducted by sending questionnaires to 330 FDR of breast cancer patients treated in the Department of Surgery, University of Hong Kong BSE behavior was studied with respect to its frequency, awareness, completeness and confidence of practice Results 110 subjects returned the questionnaires with a response rate of 33% The mean age of the respondent was 37 years Only 57 women (52%) were practicers The practicers have a stronger BSE awareness ( P <0 01) and a lower mean score on thought barriers ( P =0 002) than the non practicers 40% of the practicers gain their BSE knowledge through clinicians and their mean period of practice was 3 2 years 68% of the practicers performed BSE completely The overall confidence rate was 35%, but the rate was 43% among those who performed complete BSE Thirteen factors possibly related to the completeness and rate of confidence of BSE examination were studied The only factor that significantly determined completeness was the time spent for each examination ( P =0 002) The complete practicers required a longer time than the incomplete practicers (6 60 and 2 96?min, respectively) Women with a stronger BSE intention ( P =0 001) and a lower mean score on thought barriers ( P =0 001) performed the examination confidently Conclusions Slightly over half of the FDR practice BSE The majority perform a complete BSE but they are not confident in finding abnormalities Women spending more time on BSE are associated with a higher rate of completeness However, only those with a stronger BSE intention and lesser thought barriers are more confident in their | Kelvin K C Ng, Fung S Y and Louis W C Chow DepartmentofSurgery (NgKKCandChowLWC)&NursingStudies (FungSY ) ,TheUniversityofHongKong ,QueenMaryHospital ,HongKong ,China | 2000 | Chinese Medical Journal2000,,12: | 4 |
| 3 | Determination of carbonyl compounds in air by electrochromatography显示文摘 | Fung Y S Long Y | 2001 | Electrophoresis2001,22,11: | 2 |
| 4 | Log-Add approximation on-line noise compensation method adopting robust decision rules for robust digits recognition 显示文摘 | Yao K S Bertram E Shi Fung P | 2000 | Chinese Journal of Electronics2000,9,3: | 2 |
| 5 | Electrochemdical and bioelectro chemistry properties of room-temperature ionic liquids and carbon composite materials 显示文摘 | Fung Y S Zhu D R Fung Y S Zhu D R | 2002 | J Electrochem Soc2002,149,: | 1 |
| 6 | Abscisic acid inhibits type 2C protein phosphatases via the PYR/ PYL family of START proteins显示文摘 | PARK S Y FUNG P NISHIMURA N JENSEN D R FFUJII ZHAO Y LUMBA S SANTIAGO J RODRIGUES A CHOW T F | 2009 | Science2009,324,: | 1 |
| 7 | Current achievements using ProteinChip Array technology显示文摘 | Weinberger S R Dalmasso E A Fung E T | 2002 | Curr Opin Chem Biol2002,6,1: | 1 |
| 8 | Room Temperature Molten Salt as Medium for Lithium Battery显示文摘 | Fung Y S Zhou R Q | 1999 | J Power Sources1999,81,: | 1 |
| 9 | Self-Assembled Monolayers as the Coating in a Quartz Piezoelectric Crystal Immunosensor To Detect Salmonella in Aqueous Solution显示文摘 | Fung Y S Wong Y Y | 2001 | Anal Chem2001,73,: | 1 |
| 10 | Higher-order multivariate Markov chains and their applications显示文摘 | Ching W K Ng M K Fung E S | 2008 | Linear Algebra and its Applications2008,428,2: | 1 |
| 11 | Investor Legal Protection and Earnings Management:A Study of Chinese H-Shares and Hong Kong Shares显示文摘 | Fung S Y Su L Gul R J | 2013 | Journal of Accounting and Public Policy2013,32,05: | 1 |
| 12 | NMR study of cyclodextrin inclusion of fluorocarbon surfactants in solution显示文摘 | GUO W FUNG B M CHRISTIAN S D | 1992 | Langmuir1992,8,2: | 1 |
| 13 | Nutrient budgets in intensive shrimp ponds: implications for sustainability显示文摘 | FUNGE S BRIGGS M R P | 1998 | Aquaculture1998,164,18: | 1 |
| 14 | Psychometric properties of the Chinese version of the mini-mental adjustment to cancer (MINI-MAC) scale显示文摘 | Ho S M Y Kam Fung W Chan C L W | 2003 | Psycho Oncol2003,12,6: | 1 |
| 15 | An in vitro evaluation ofthe effectiveness of endotracheal suction catheters显示文摘 | Shah S Fung K Brim S | 2005 | Chest2005,128,5: | 1 |
| 16 | Preimplantation genetic analysis of translocations:case-specific probes for interphase cell analysis显示文摘 | MunnéS Fung J Cassel MJ | 1998 | Hum Reprod1998,102,6: | 1 |
| 17 | Crypt loss is a marker of clinical se- verity of acute gastrointestinal graft - versus - host disease 显示文摘 | Melson J Jakate S Fung H | 2007 | Am J Hematol2007,82,10: | 1 |
| 18 | Bit error simulation for/4 DQPSK mobile radio communications using TwoRay and measurement-based impulse response models显示文摘 | Fung V Rappaport T S Thoma B | | 0,,03: | 1 |
| 19 | Higher-order multivariate Markov chains and their applications显示文摘 | Ching W K Ng M K Fung E S | 2008 | Linear Algebra and its Applica- tions2008,428,2: | 1 |
| 20 | Particle release from respirators, part I: detennination of the effect of part -icle size, drop height, and load显示文摘 | BIRKNER J S FUNG D HINDS W C | 2011 | J Occup Environ Hyg2011,8,1: | 1 |