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| 1 | Helicobacter pylori associated chronic gastritis,clinical syndromes,precancerous lesions,and pathogenesis of gastric cancer development显示文摘Helicobacter pylori(H.pylori)infection is well known to be associated with the development of precancerous lesions such as chronic atrophic gastritis(AG),or gastric intestinal metaplasia(GIM),and cancer.Various molecular alterations are identified not only in gastric cancer(GC)but also in precancerous lesions.H.pylori treatment seems to improve AG and GIM,but still remains controversial.In contrast,many studies,including meta-analysis,show that H.pylori eradication reduces GC.Molecular markers detected by genetic and epigenetic alterations related to carcinogenesis reverse following H.pylori eradication.This indicates that these changes may be an important factor in the identification of high risk patients for cancer development.Patients who underwent endoscopic treatment of GC are at high risk for development of metachronous GC.A randomized controlled trial from Japan concluded that prophylactic eradication of H.pylori after endoscopic resection should be used to prevent the development of metachronous GC,but recent retrospective studies did not show the tendency.Patients with precancerous lesions(molecular alterations)that do not reverse after H.pylori treatment,represent the'point of no return'and may be at high risk for the development of GC.Therefore,earlier H.pylori eradication should be considered for preventing GC development prior to the appearance of precancerous lesions. | Jiro Watari Nancy Chen Peter S Amenta Hirokazu Fukui Tadayuki Oshima Toshihiko Tomita Hiroto Miwa Kheng-Jim Lim Kiron M Das | 2014 | World Journal of Gastroenterology2014，20，18： | 60 |
| 2 | Flocculant of cell walls of brewer′s yeast and effects of metal ions, protein-denaturants and enzyme treatments显示文摘 | Nishihara H Toraya T Fukui S | 1982 | Arch Microbiol1982，131，： | 2 |
| 3 | Cranial bone defect healingisaccelerated by mesenchymal stem cells induced by coadministration ofbone morphogenetic protein-2 and basic fibroblast growth factor显示文摘 | AKITA S FUKUI M NAKAGAWA H | 2004 | Wound Repair Regen2004，12，2： | 1 |
| 4 | Focal brain edema and natriuretic peptides in patients with subarachnoid hemorrhage 显示文摘 | FUKUI S NAWASHIRO H OTANI N | 2003 | Aeta Neurochir (Wien)2003，86，： | 1 |
| 5 | Multiple primary malig- nant neoplasms associated with prostate cancer in 312 consecu- tive case显示文摘 | Kawakami S Fukui I Yonese J | 1997 | Urol Int1997，59，4： | 1 |
| 6 | Aortic root replacement with Freestyle stentless valve for complex aortic root infection 显示文摘 | Fukui T Suehiro S Shibata T | 2003 | J Thorac Cardiovasc Surg2003，125，1： | 1 |
| 7 | Theoretical study on fabrication of functionally graded material with density gradient by a centrifugal solid-particle method显示文摘 | OGAWA T WATANABE Y SATO H KIM I S FUKUI Y | 2006 | Composites Part A2006，37，12： | 1 |
| 8 | Early and midtermresults of off-pump coronary artery bypass grafting 显示文摘 | Fukui T Takanaski S Hosoda Y | 2007 | Ann Thorac Surg2007，83，1： | 1 |
| 9 | Moyamoya disease显示文摘 | Fukui M Kono S Sueishi K | 2000 | Neuropathology2000，，： | 1 |
| 10 | REG I alpha protein mediates an anti-apoptotic effect of STAT3 signaling in gastric cancer cells显示文摘 | Sekikawa A Fukui H Fujii S | 2008 | Carcinogenesis2008，29，1： | 1 |
| 11 | Computer evaluation of sprinkler irrigation uniformity显示文摘 | Fukui Y Nakanishi K Okayama S | 1980 | Irrigation Science1980，2，1： | 1 |
| 12 | Overexpression of transforming growth factor β1 in smooth muscle cells of human abdominal aortic aneurysm显示文摘 | Fukui D Miyagawa S Soeda J | 2003 | Eur J Vasc Endovasc Surg2003，25，6： | 1 |
| 13 | Expression of reg I alpha pro- tein in human gastric cancers显示文摘 | Fukui H Fujii S Takeda J | 2004 | Digestion2004，69，3： | 1 |
| 14 | REG Ialpha protein mediates an anti-apoptotic effect of STAT3 signaling in gastric cancer cells显示文摘 | Sekikawa A Fukui H Fujii S | 2008 | Carcinogenesis2008，29，1： | 1 |
| 15 | Fatigue and sleep under large summer temperature differences 显示文摘 | FUJI1 H FUKUI)A S NARUMI D | 2015 | Environmental Research2015，138，： | 1 |
| 16 | Multiple primary malignant neoplasms associated with prostate cancer in 312 consecutive cases显示文摘 | KAWAKAMI S FUKUI I YONESE J | 1997 | Urol Int1997，59，4： | 1 |
| 17 | Powder prepared by spray pyrolysis as an electrode material for solid oxide fuel cells显示文摘 | MARIC R FUKUI T OHARA S | 2000 | J Mater Sci2000，35，3： | 1 |
| 18 | Different properties of two types of auxin-binding sites in membrance from maixe maize coleoptiles显示文摘 | Inohara N Fukui T | 1988 | Planta1988，175，： | 1 |
| 19 | Type-2 astrocytes show intracellular Ca2+ elevation in response to various neuroactive substances显示文摘 | Fukui H Ito S | 1991 | Neurosci Lett1991，128，2： | 1 |
| 20 | Differential activation of mitogen-activated protein kinase pathways after traumatic brain injury in the rat hippocampus 显示文摘 | Otani N Nawashiro H Fukui S | 2002 | Cereb Blood Flow Metab2002，22，3： | 1 |
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