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| 1 | Factors associated with time to laparoscopic cholecystectomy for acute cholecystitis显示文摘AIM: To determine patient and process of care factors associated with performance of timely laparoscopic cholecystectomy for acute cholecystitis. METHODS: A retrospective medical record review of 88 consecutive patients with acute cholecystitis was conducted. Data collected included demographic data, co-morbidities, symptoms and physical findings at presentation, laboratory and radiological investigations, length of stay, complications, and admission service (medical or surgical). Patients not undergoing cholecystectomy during this hospitalization were excluded from analysis. Hierarchical generalized linear models were constructed to assess the association of pre-operative diagnostic procedures, presenting signs, and admitting service with time to surgery.RESULTS: Seventy cases met inclusion and exclusion criteria, among which 12 were admitted to the medical service and 58 to the surgical service. Mean ± SD time to surgery was 39.3 ± 43 h, with 87% of operations performed within 72 h of hospital arrival. In the adjusted models, longer time to surgery was associated with number of diagnostic studies and endoscopic retrograde cholangio-pancreatography (ERCP, P = 0.01) as well with admission to medical service without adjustment for ERCP (P < 0.05). Patients undergoing both magnetic resonance cholangiopancreatography (MRCP) and computed tomography (CT) scans experienced the longest waits for surgery. Patients admitted to the surgical versus medical service underwent surgery earlier (30.4 ± 34.9 vs 82.7 ± 55.1 h, P < 0.01), had less post-operative complications (12% vs 58%, P < 0.01), and shorter length of stay (4.3 ± 3.4 vs 8.1 ± 5.2 d, P < 0.01).CONCLUSION: Admission to the medical service and performance of numerous diagnostic procedures, ERCP, or MRCP combined with CT scan were associated with longer time to surgery. Expeditious performance of ERCP and MRCP and admission of medically stable patients with suspected cholecystitis to the surgical service to speed up time to surgery should be considered. | Chris N Daniak David Peretz Jonathan M Fine Yun Wang Alan K Meinke William B Hale | 2008 | World Journal of Gastroenterology2008，14，7： | 13 |
| 2 | 不同含量碳水化合物饮食对大鼠心脏和脑18^F-FDG摄取的影响显示文摘目的探讨不同含量碳水化合物饮食对大鼠心脏和脑组织18F-FDG摄取的影响。方法以标准饮食饲养2周后,保持饮食总能量不变,将15只Wistar大鼠随机分为3组:低碳水化合物组(LC)、中碳水化合物组(IC)和高碳水化合物组(HC);每组大鼠每种饮食饲养4周后,对动物行18F-FDGPET全身显像,于第2天尾静脉取血测定酮体、葡萄糖、胰岛素和胰高血糖素的含量。图像经计算机处理,获取心脏和脑的最大标准摄取值(SUVmax)。结果心脏SUVmax分别为:LC组3.27±0.43,IC组10.92±0.89,HC组10.95±0.81;脑SUVmax:LC组4.78±0.19,IC组4.04±0.15,HC组3.77±0.24。LC组与IC和HC组之间的差异均有统计学意义(P<0.001),IC和HC组间差异无统计学意义。LC组酮体为(726.10±65.95)μmol/L,约为IC和HC组的6~7倍;血清酮体水平与心脏SUVmax呈负相关(r=-0.764,P<0.001),与脑SUVmax呈正相关(r=0.569,P<0.001);各组间血清胰岛素、血糖和胰高血糖素的差异均无统计学意义。结论长期极低碳水化合物饮食使大鼠心脏对FDG的摄取明显降低,而脑组织对葡萄糖的摄取略有增加。 | 缪蔚冰 王荣福 BLAUFOX M Donald FINE Eugene J KOBA Wade | 2009 | 中国医学影像技术2009，，7： | 4 |
| 3 | Comparison of a disease-specific and a generic severity of illness measure for patients with community-acquired pneumonia显示文摘 | FINE M J HANUSA BH LAVE JR | 1995 | Chinese Journal of General Internal Medicine1995，10，： | 1 |
| 4 | Molecular mechanism for the umami taste synergism显示文摘 | ZHANG Feng KLEBANSKY B FINE R M | | 0，，52： | 1 |
| 5 | Embryonic, juvenile, and adult development of the toadfish sonic muscle显示文摘 | LOESSER K E RAFI J FINE M L | 1997 | The Anatomical Record1997，249，4： | 1 |
| 6 | Kinetic evidence for an enamine mechanism in the acid-catalyzed cleavage of β-amino alcohols显示文摘 | Freese R F Greene M G | 1973 | J Org C he m1973，38，11： | 1 |
| 7 | Plastic work of fatigue crack propa gation in steels and aluminum alloys 显示文摘 | Liaw P K Kwun S I Fine M E | 1981 | Metallurgical Transactions1981，12，： | 1 |
| 8 | Pancreatic expression of interferon-gamma protects mice from lethal coxsackievirus B3 infection and subsequent myocarditis 显示文摘 | Horwitz M S La-Cava A Fine C | 2000 | Nat Med2000，6，6： | 1 |
| 9 | Metal fume fever显示文摘 | GORDON T FINE J M | 1993 | Occup Med1993，8，3： | 1 |
| 10 | Open burning of agricultural biomass: Physical and chemical properties of particle-phase emissions显示文摘 | Hays M D Fine P M Geron C D | 2005 | Atmospheric Environment2005，39，36： | 1 |
| 11 | Oligomeric proanthocyanidin complexes:history,structure and phyopharmaceutical applications显示文摘 | FINE A M | 2000 | Alternative Medicine Review2000，5，2： | 1 |
| 12 | Electrical Conductivity Versus Strength in a Precipitation Hardened Alloy 显示文摘 | Miyake J Fine M E | 1992 | Acta Metal Mater1992，40，4： | 1 |
| 13 | Tribological Prop- erties of Aluminum Alloy Matrix TiB^2 Composite Prepared by in Situ Processing显示文摘 | Caraeostas C A Chiou W A Fine M E | 1997 | Metallurgical and Materials Transactions A1997，28，2： | 1 |
| 14 | Chemical characterization of fine particle emissions from fireplace combustion of woods grown in the northeastern United States显示文摘 | Fine P M Cass G R Simoneit B R T 2001 | 2001 | Environ Sci Technol2001，35，13： | 1 |
| 15 | The COMS randomized trial of iodine 125 brachytherapy for choroidal melanoma:characteris- tics of patients enrolled and not enrolled 显示文摘 | Diener - West M Earle JD Fine SL | 2011 | Arch Ophthalmol2011，119，： | 1 |
| 16 | Activity of linezolid against gram-positive coci possessing genes conferring resistance to protein synthesis inhibitors 显示文摘 | FINES M LECLERCQ R | 2000 | J Antimicrob Chemother2000，45，6： | 1 |
| 17 | New phacoemulsification technologies 显示文摘 | Fine IH Packer M Hofman RS | 2002 | Cataract Refract Surg2002，28，6： | 1 |
| 18 | Observational study of inhaled corticosteroids on outcomes for COPD patients with pneumonia 显示文摘 | Chen D Restrepo MI Fine M J | 2011 | Am J Respir Crit Care Med2011，184，3： | 1 |
| 19 | Chemical characterization of fine particle emissions from the fireplace combustion of woods grown in the southern United States显示文摘 | Fine P M Cass G R Simoneit B R T 2002 | 2002 | Environ Sci Technol2002，36，7： | 1 |
| 20 | Adaptive immune response in os- teoclastic bone resorption induced by orally administered Aggregatibacter actinomycetemcomi- tans in a rat model of periodontal disease 显示文摘 | Li Y Messina C Bendaoud M Fine DH Schreiner H Tsiagbe VK | 2010 | Mol Oral Microbiol2010，25，4： | 1 |
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