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	题名	作者	年代	出处	被引量
1	Ursodeoxycholic acid improves gastrointestinal motility defects in gallstone patients显示文摘AIM: To simultaneously evaluate the presence of defects in gallbladder and gastric emptying, as well as in intestinal transit in gallstone patients (GS) and the effect of chronic ursodeoxycholic acid (UDCA) administration on these parameters and on serum bile acids and clinical outcome in GS and controls (CTR). METHODS: After a standard liquid test meal, gallbla-dder and gastric emptying (by ultrasound), oroileal transit time (OITT) (by an immunoenzymatic technique) and serum bile acids (by HPLC) were evaluated before and after 3 mo of UDCA (12 mg/kg bw/d) or placebo administration in 10 symptomatic GS and 10 matched healthy CTR. RESULTS: OITT was longer in GS than in CTR (P < 0.0001); UDCA significantly reduced OITT in GS (P < 0.0001), but not in CTR. GS had longer gastric half-emptying time (t1/2) than CTR (P < 0.0044) at baseline; after UDCA, t1/2 significantly decreased (P < 0.006) in GS but not in CTR. Placebo administration had no effect on gastric emptying and intestinal transit in both GS and CTR. CONCLUSION: The gallstone patient has simultaneous multiple impairments of gallbladder and gastric emptying, as well as of intestinal transit. UDCA administration restores these defects in GS, without any effect in CTR. These results confirm the pathogenetic role of gastrointestinal motility in gallstone disease and suggest an additional mechanism of action for UDCA in reducing bile cholesterol supersaturation.	A Colecchia G Mazzella L Sandri F Azzaroli M Magliuolo P Simoni ML Bacchi-Reggiani E Roda D Festi	2006	World Journal of Gastroenterology2006，12，33：	4
2	^13C-methacetin breath test for monitoring hepatic function in cirrhotic patients before and after liver transplantation显示文摘	Petrolati A Festi D De Berardinis G	2003	Aliment Pharmacol Ther2003，18，8：	1
3	Natural history of gall-stone disease: Expectant management or active treat- ment? Re-sults from a population-based cohort study显示文摘	Festi D Reggiani ML Attili AF et a l	2010	J Gastroenterol Hepatol2010，25，4：	1
4	Rifaximin in the treatment of chronic hepatic encephalopathy ? resultes of a multicenter study of efficacy and safety显示文摘	Festi D Mazzella G Orsini M	1993	Current Therapeutic Research1993，54，5：	1
5	Antioxidant properties of ursodeoxycholic acid 显示文摘	LAPENNA D CILOFANI G FESTI D	2002	Biochem Pharmacol2002，64，11：	1
6	Long-term results with interferon therapy in chronic type B hepatitis:A prospective randomized trial显示文摘	Mazzella G Saracco G Festi D	1999	Am J Gastroenterol1999，94，8：	1
7	Hepatic steato- sis in obese patients:clinical aspects and prognostic significance 显示文摘	Festi D Colecchia A Sacco T	2004	Obesity Reviews2004，5，1：	1
8	Natural history of gallstone disease : Expectant management or active treatment? Resuhs from a population-based cohort study显示文摘	Festi D Reggiani MLB Attili AF	2010	J Gastroenterol Hepato12010，25，4：	1
9	Characterization of calcareous deposits in artificial seawater by impedance techniques显示文摘	C Barchiche C Deslouis D Festy	2003	Electrochim Acta2003，48，12：	1
10	Safety of interferon beta treatment for chronic HCV hepatitis 显示文摘	Festi D Sandri L Mazzella G	2004	World J Gastroenterol2004，10，：	1
11	Acquired gallstone opacification during cholelitholytic treatment with chenodeoxyholic,ursodeoxycholic,and tauroursodeoxycholic acids显示文摘	Bazzoli F Festi D Mazzella G	1995	The American journal of gastroenterology1995，90，6：	1
12	Modified transparent SnO 2 electrodes as efficient and stable cathodes for oxygen reduction显示文摘	T El Moustafid H Cachet B Tribollet 1 D Festy	2002	Electrochimica Acta2002，，8：	1
13	Natural history of gallstone disease: Expectant management or active treatment? Results from a population-based cohort study 显示文摘	Festi D Reggiani ML Attili AF	2010	J Gastroenterol Hepatol2010，25，4：	1
14	Long-term results with interferon therapy in chronic type B hepatitis: a prospective randomized trial显示文摘	Mazzella G Saracco G Festi D	1999	Am J Gastroenterol1999，94，8：	1
15	Natural history of gallstone disease:Expectant management or active treatment?Results from a populatonbased cohorl study显示文摘	Festi D Reggiani M L Attili A F	2010	J Gastroenterol Hepatol2010，2，54：	1
16	Hepatic Steatosis in Obese Patients: Clinical Aspects and Prognostic Significance显示文摘	Festi D Colecchia A Sacco T	2004	Obes Rev2004，5，1：	1
17	Characterization of calcareous deposits in artificial sea water by impedances techniques: 3-deposit of CaCO3 in the presence of Mg^2+ 显示文摘	BARCHICHE C DESLOUIS C FESTY D GIL O MAILLOT V TOUZAIN S TRIBOLLET B	2003	Electrochimica Acta2003，48，：	1
18	Safety of interferon beta treatment for chronic HCV hepatitis显示文摘	Festi D Sandri L Mazzella G	2004	World J Gastroenterol2004，10，1：	1
19	Natural history of gallstone disease: Expectant management or active treatment? Results from a population-based cohort study显示文摘	FESTI D GEGGIANI M L ATTIII A E	2010	J Gastroenterol Hepatol2010，25，4：	1
20	Hepatic steatosis in obese patients:clinical aspects and prognostic significance显示文摘	Festi D Colecchia A Sacco T	2004	Obesity Reviews2004，5，1：	1

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