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| 1 | Computed tomography-guided percutaneous core needle biopsy in pancreatic tumor diagnosis显示文摘AIM: To evaluate the techniques, results, and complications related to computed tomography(CT)-guided percutaneous core needle biopsies of solid pancreatic lesions.METHODS: CT-guided percutaneous biopsies of solid pancreatic lesions performed at a cancer reference center between January 2012 and September 2013 were retrospectively analyzed. Biopsy material was collected with a 16-20 G Tru-Core needle(10-15 cm; Angiotech, Vancouver, CA) using a coaxial system and automatic biopsy gun. When direct access to the lesion was not possible, indirect(transgastric or transhepatic) access or hydrodissection and/or pneumodissection maneuvers were used. Characteristics of the patients, lesions, procedures, and histologic results were recorded using a standardized form. RESULTS: A total of 103 procedures included in the study were performed on patients with a mean age of 64.8 year(range: 39-94 year). The mean size of the pancreatic lesions was 45.5 mm(range: 15-195 mm). Most(75/103, 72.8%) procedures were performed via direct access, though hydrodissection and/or pneumodissection were used in 22.2%(23/103) of cases and indirect transhepatic or transgastric access was used in 4.8%(5/103) of cases. Histologic analysis was performed on all biopsies, and diagnoses were conclusive in 98.1%(101/103) of cases, confirming3.9%(4/103) of tumors were benign and 94.2%(97/103) were malignant; results were atypical in 1.9%(2/103) of cases, requiring a repeat biopsy to diagnose a neuroendocrine tumor, and surgical resection to confirm a primary adenocarcinoma. Only mild/moderate complications were observed in 9/103 patients(8.7%),and they were more commonly associated with biopsies of lesions located in the head/uncinate process(n =8), than of those located in the body/tail(n = 1) of the pancreas, but this difference was not significant.CONCLUSION: CT-guided biopsy of a pancreatic lesion is a safe procedure with a high success rate, and is an excellent option for minimally invasive diagnosis. | Chiang J Tyng Maria Fernanda A Almeida Paula NV Barbosa Almir GV Bitencourt José Augusto AG Berg Macello S Maciel Felipe JF Coimbra Luiz Henrique O Schiavon Maria Dirlei Begnami Marcos D Guimares Charles E Zurstrassen Rubens Chojniak | 2015 | World Journal of Gastroenterology2015，21，12： | 14 |
| 2 | Management of oligometastatic non-small cell lung cancer patients:Current controversies and future directions显示文摘Oligometastatic non-small cell lung cancer(NSCLC)describes an intermediate stage of NSCLC between localized and widely-disseminated disease.This stage of NSCLC is characterized by a limited number of metastases and a more indolent tumor biology.Currently,the management of oligometastatic NSCLC involves radical treatment(radiotherapy or surgery)that targets the metastatic lesions and the primary tumor to achieve disease control.This approach offers the potential to achieve prolonged survival in patients who,in the past,would have only received palliative measures.The optimal therapeutic strategies for the different scenarios of oligometastatic disease(intracranial vs extracranial disease,synchronous vs metachronous)remain undefined.Given the lack of head-to-head studies comparing radiotherapy to surgery in these patients,the decision to apply surgery or radiotherapy(with or without systemic treatment)must be based on prognostic factors that allow us to classify patients.This classification will allow us to select the most appropriate therapeutic strategy on an individualized basis.In the future,the molecular or microRNA profiles will likely improve the treatment selection process.The objective of the present article is to review the most relevant scientific evidence on the management of patients with oligometastatic NSCLC,focusing on the role of radiotherapy and surgery.We also discuss areas of controversy and future directions. | Felipe Counago Javier Luna Luis Leonardo Guerrero Blanca Vaquero María Cecilia Guillén-Sacoto Teresa González-Merino Begona Taboada Verónica Díaz Belén Rubio-Viqueira Ana Aurora Díaz-Gavela Francisco JoséMarcos Elia del Cerro | 2019 | World Journal of Clinical Oncology2019，10，10： | 5 |
| 3 | Coronary physiology assessment in the catheterization laboratory显示文摘Physicians cannot rely solely on the angiographic appearance of epicardial coronary artery stenosis when evaluating patients with myocardial ischemia. Instead, sound knowledge of coronary vascular physiology and of the methods currently available for its characterization can improve the diagnostic and prognostic accuracy of invasive assessment of the coronary circulation, and help improve clinical decision-making. In this article we summarize the current methods available for a thorough assessment of coronary physiology. | Felipe Díez-delhoyo Enrique Gutiérrez-Ibanes Gerard Loughlin Ricardo Sanz-Ruiz María Eugenia Vázquez-álvarez Fernando Sarnago-Cebada Rocío Angulo-Llanos Ana Casado-Plasencia Jaime Elízaga Francisco Fernández Avilés Diáz | 2015 | World Journal of Cardiology2015，7，9： | 2 |
| 4 | A simple description of age-related changes in crystalline lens thickness显示文摘 | Garcia-Domene MC Díez-Ajenjo MA Gracin V Felipe A Artigas JM | | 0，，05： | 1 |
| 5 | ASCEND-2: A single-arm, open-label, multicenter phase II study of ceritinib in adult patients (pts) with ALK- rearranged (ALK+) non-small cell lung cancer (NSCLC) previously treated with chemotherapy and crizotinib (CRZ)显示文摘 | Mok T Spigel D Felip E | 2015 | J Clin Oncol2015，33，： | 1 |
| 6 | Co translational,in- traribosomal cleavage of polypeptides by the foot-and mouth dis ease virus 2A peptide显示文摘 | De Felipe P Hughes L E Ryan M D | 2003 | J Biol Chem2003，278，11： | 1 |
| 7 | Is Export-led Growth Passe? Implications for Developing Asia显示文摘 | Felipe J A D Bank | 2003 | Citeseer2003，，： | 1 |
| 8 | Molecular characterization and evaluation of mycorrhizal capacity of SuiUus isolates from central spain for the selection of fungal inoculants 显示文摘 | Ruiz D B Rinc6n A M Felipe M R | 2006 | Mycorrhiza2006，16，7： | 1 |
| 9 | Overexpression of c-erbB-2 in epithelial ovarian cancer显示文摘 | Felip E Del Campo JM Rubio D | 1995 | Cancer1995，75，8： | 1 |
| 10 | Co-translational,intraribosomal cleavage of polypetides by the foot-and-mouth disease virus 2A peptide显示文摘 | De Felipe P Hughes L E Ryan M D | 2003 | J Biol Chem2003，278，11： | 1 |
| 11 | Non - small - cell lung cancer: ESMO clini- cal recommendations for diagnosis, treatment and follow - up 显示文摘 | D'Addario G Felip E | 2009 | Ann Oncol2009，20，4： | 1 |
| 12 | Non- small-cell lung cancer: ESMO clinical recommendations for diagnosis, treatment and follow up显示文摘 | D'Addario G Felip E ESMO Guidelines Working Group | 2008 | Ann Oncology2008，19，2： | 1 |
| 13 | Non-small-cell lung cancer: ESMO clinical recommendations for diagnosis, treatment and follow-up显示文摘 | D'Addario G Felip E ESMO Guidelines Working Group | 2009 | Ann Oncol2009，20，4： | 1 |
| 14 | Non- small-cell lung cancer: ESMO clinical recommendations for diagno- sis, treatment and follow-up显示文摘 | D'Addario G Felip E ESMO Guidelines Working Group | 2009 | Ann Oncol2009，204，： | 1 |
| 15 | Growth, feed efficiency and condition of common Octopus fed two formulated moist diets显示文摘 | Jesus C V Maria D H Felipe A G | 2008 | Aquaculture2008，275，： | 1 |
| 16 | Overexpression of C-erbB-2 in epithelial ovarian cancer显示文摘 | Felip E Del Campo JM Rugbio D | 1995 | Cancer1995，75，8： | 1 |
| 17 | Enzyme immobilized in MCM-41 molecular sieve显示文摘 | Felipe J D Kenneth J | 1996 | Journal of Molecular Catalysis B:Enzymatic1996，2，： | 1 |
| 18 | Usefulness of the Neuroform stent for the treatment of cerebral aneurysms:results at initial (3-6-mo)follow up显示文摘 | Felipe CA Vivek RD | 2005 | Neurosurgery2005，56，6： | 1 |
| 19 | The C-terminal tetrapeptide of phaseolin is sufficient to target green flurescent protein to the vacuole显示文摘 | Frigerio L Foresti O Felipe D H | 2001 | J Plant Physiol2001，158，： | 1 |
| 20 | Non-small cell lung cancer:ESMO clinical recommendations for diagnosis,treatment and follow-up显示文摘 | D'Addario G Felip E | 2008 | Ann Oncol2008，19，： | 1 |
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