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| 1 | 最新AD研究用诊断标准:IWG-2标准显示文摘在过去的8年中,国际工作组织(IWG)和美国国立老化研究院-阿尔茨海默协会(NIA-AA)建立了阿尔茨海默病(AD)诊断标准,它能更好地定义AD的临床表型,整合了生物标记物于诊断流程中,并覆盖了疾病的全程。本意见书充分地权衡了IWG标准的优缺点,建议改进诊断框架。依据这些改进,AD的诊断变得简单,只要有恰当的AD临床表型(典型或不典型)和与AD的病理相一致的病理生理学生物标志物出现。我们认为疾病的下游的定位性生物标志,如容积性磁共振成像(MRI)和氟脱氧葡萄糖-正电子发射型计算机断层成像(FDG-PET)等,适合更好地测量和监测疾病过程。本文还详述了非典型性AD、混合性AD和AD临床前期的特异诊断标准。 | 陈刚 曹雯炜 俞羚 糜建华 Dubois B Feldman HH Jacova C Hampel H Molinuevo JL Blennow K DeK osky ST Gauthier S Selkoe D Bateman R Cappa S Crutch S Engelborghs S Frisoni GB Fox NC Galasko D Habert MO Jicha GA Nordberg A Pasquier F Rabinovici G Robert P Rowe C Salloway S Sarazin M Epelbaum S de Souza LC Vellas B Visser PJ Schneider L Stern Y Scheltens P Cummings JL | 2014 | 神经病学与神经康复学杂志2014，11，3： | 31 |
| 2 | Global elemental maps of the Moon: The lunar prospector gamma ray spectromet er显示文摘 | Lawrence D J Feldman W C Barraclough B L | 1998 | Science1998，281，： | 1 |
| 3 | Clinical determination of myocardial vs load effects of OPC-18790,a novel intravenous agent for the treatment of patients with congestive heart failure显示文摘 | Feldman M D Haber H L Wu C C | 1993 | Circulation1993，88，42： | 1 |
| 4 | A projection approach to ro- bust adaptive beamforming显示文摘 | Feldman D D Griffit hs L J | 1994 | IEEE Transactions on Signal Processing1994，42，4： | 1 |
| 5 | Diabetic neuropathies显示文摘 | LITTLE A A EDWARDS J L FELDMAN E L | 2007 | Pract Neurol2007，，7： | 1 |
| 6 | Use of coronary Palmaz-Sehatz stent in the pereutaneous treatment of an intracranial carotid artery stenosis显示文摘 | Feldman RL Trigg L Gaudier J | 1996 | Cathet Cardiovasc Diagn1996，38，3： | 1 |
| 7 | Retinoic acid signaling restricts the cardiac progenitor pool 显示文摘 | KEEGAN B R FELDMAN J L BEGEMANN G | 2005 | Science2005，307，5707： | 1 |
| 8 | Changing trends in mortality and admissions to hospital for elderly patients with congestive heart failure in Montreal显示文摘 | Feldman DE Thivierge C Guerard L | 2001 | CMAJ2001，165，8： | 1 |
| 9 | Differential expression of matrix metalloproteinase after stent implatation and balloon angioplasty in the hyper-eholesterolemic rabbit显示文摘 | Mazighi M Scheuble A | 2001 | Cireulation2001，103，25： | 1 |
| 10 | The Contribution of Morphological and Semantic Relatedness to Repetition Priming at Short and Long Lags: Evidence from Hebrew 显示文摘 | BENTIN S FELDMAN L 13 | 1990 | Quarterly Journal of Experimental Psychology1990，42，： | 1 |
| 11 | Six year report of the periodontal health offixed and removable partial denture abutment teeth显示文摘 | Risson L Feldman RS Kapur KK | 1985 | J Prosthet Dent1985，54，： | 1 |
| 12 | Performance characteristics of a dual focus X-ray alignment microscope 显示文摘 | FELDMAN M LIU L PHANI S | 1995 | Journal of Vacuum Science & Technology: B1995，13，6： | 1 |
| 13 | High temperature, high pressure electrostatic precipitation显示文摘 | Bush J R Feldman P L Robinson M | 1979 | Journal of the Air Pollution Control Association1979，29，4： | 1 |
| 14 | Characterization of a Calcium/calmodulin-dependent Protein Kinase Homolog from Maiz Roots Showing Light-regulated Gravitropism显示文摘 | Lu Y T Hidaka H Feldman L J | 1996 | Planta1996，199，： | 1 |
| 15 | Antiangiogenic gene therapy of cancer utilizing a recombinant adenovirus to elevate systemic endostatin levels in mice显示文摘 | Feldman A L Restifo N P Alexander H R | 2000 | Cancer Res2000，，60： | 1 |
| 16 | Interleukin-10 inhibits intimal hyperplasia after angioplasty or stent implantation in hypercholesterolemic rabbits显示文摘 | Feldman LJ Aguirre L Ziol M | 2000 | Circulation2000，101，8： | 1 |
| 17 | Six year report of the peri- edontal health of fixed and removable partial denture abutment teeth显示文摘 | Risson L Feldman RS Kapur KK | 1985 | J Prosthet Dent1985，54，4： | 1 |
| 18 | Small animal model of weightlessness for pharmacokinetic evaluation 显示文摘 | FELDMAN S BRUNNER L J | 1994 | Clin Pharmacol1994，34，： | 1 |
| 19 | A projection approach for ro- bust adaptive beamforming 显示文摘 | Feldman D D Griffiths L J | 1994 | IEEE Transactions on Signal Processing1994，42，4： | 1 |
| 20 | Use of supplemen- tal vitamin D among infants breastfed for prolonged periods 显示文摘 | TAYLOR J A GEYER L J FELDMAN K W | 2010 | Pediatrics2010，125，1： | 1 |
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