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| 1 | Chylous ascites secondary to hyperlipidemic pancreatitis with normal serum amylase and lipase显示文摘A 54-year old man with a family history of hyperlipidemia was admitted with a 12 h history of severe generalized abdominal pain associated with nausea, vomiting and abdominal distension. Examination of the abdomen revealed tenderness in the periumblical area with shifting dullness. Serum pancreatic amylase was 29 IU/L and lipase 44 IU/L, triglyceride 36.28 mmol/L. Ultrasound showed ascites. CT of the abdomen with contrast showed inflammatory changes surrounding the pancreas consistent with acute pancreatitis. Ultrasound (US) guided abdomen paracentesis yielded a milky fluid with high triglyceride content consistent with chylous ascites. The patient was kept fasting and intravenous fluid hydration was provided. Meperidine was administered for pain relief. On the following days the patient’s condition improved and he was gradually restarted on a low-fat diet, and fat lowering agent (gemfibrozil) was begun, 600 mg twice a day. On d 14, abdomen US was repeated and showed fluid free peritoneal cavity. The patient was discharged after 18 d of hospitalization with 600 mg gemfibrozil twice a day. At the time of discharge, the fasting triglyceride was 4.2 mmol/L. After four weeks the patient was seen in the clinic, he was well. | Fahmi Yousef Khan Issa Matar | 2007 | World Journal of Gastroenterology2007，13，3： | 24 |
| 2 | 基于土壤-环境关系的更新传统土壤图研究显示文摘传统土壤图是流域管理、生态水文模型所需土壤空间分布信息的主要数据源。然而,受传统制图技术和基础数据质量所限,传统土壤图的空间详细度和属性精确度并不高。随着地理信息技术的发展,如何利用可获取的高质量空间数据和现代空间分析技术来更新传统土壤图显得十分必要。基于传统土壤图中的土壤多边形与通过模糊聚类所得环境因子组合之间存在着对应关系这一假设,本文提出了一种从传统土壤图中提取土壤-环境关系知识并利用该知识更新传统土壤图的方法。该方法包括四个步骤:对环境数据进行模糊c均值聚类获取环境因子组合;利用传统土壤图建立环境因子组合与土壤类型间的对应关系;提取土壤-环境关系知识;进行土壤推理制图。将该方法应用于加拿大New B runsw ick省的W akefield研究区,以更新该区现有的1∶20 000的传统土壤图。应用结果表明:更新后的数字土壤图显示了更详细的空间分布信息;经野外独立验证点验证,所得土壤图(制图单元为土壤组合-排水等级)精度高出原土壤图约20%。因此,该方法是一种有效的更新传统土壤图的方法,可增加土壤图的空间详细度、提高土壤图的属性精确度。 | 杨琳 Fahmy Sherif Jiao You Hann Sheldon 朱阿兴 秦承志 徐志刚 | 2010 | 土壤学报2010，47，6： | 16 |
| 3 | Relationship between vitamin D and IL-23,IL-17 and macrophage chemoattractant protein-1 as markers of fibrosis in hepatitis C virus Egyptians显示文摘AIM:To assess vitamin D in hepatitis C patients and its relationship to interleukin (IL)-23, IL-17, and macrophage chemoattractant protein-1 (MCP-1). METHODS:The study was conducted on 50 Egyptian hepatitis C virus (HCV) genotype number IV-infected patients and 25 ageand gender-matched healthy subjects. Venous blood samples were obtained. Samples were allowed to clot and sera were separated by centrifugation and stored at -20 ℃. A 25 hydroxy vitamin D assay was carried out using solid phase RIA. A 1,25 dihydroxy vitamin D assay was carried out using a commercial kit purchased from Incstar Corporation. IL-17 and -23 and MCP-1 were assayed by an enzyme immunoassay. Quantitative and qualitative polymerase chain reaction for HCV virus were done by TaqMan technology. Only HCV genotype IV-infected subjectswere included in the study. The mean ± SD were determined, a t-test for comparison of means of different parameters was used. Correlation analysis was done using Pearson's correlation. Differences among different groups were determined using the Kruskal-Wallis test. RESULTS:The mean vitamin D level in HCV patients (groupⅠ) was 15 ± 5.2 ng/mL while in control (group Ⅱ) was 39.7 ± 10.8. For active vitamin D in groupⅠas 16.6 ± 4.8 ng/mL while in group Ⅱ was 41.9 ± 7.9. IL-23 was 154 ± 97.8 in group Ⅰ and 6.7 ± 2.17 in group Ⅱ. IL-17 was 70.7 ± 72.5 in cases and 1.2 ± 0.4 in control. MCP-1 was 1582 ± 794.4 in group Ⅰand 216.1 ± 5.38 in group Ⅱ. Vitamin D deficiency affected 72% of HCV-infected patients and 0% of the control group. Vitamin D insufficiency existed in 28% of HCV-in-fected patients and 12% of the control group. One hundred percent of the cirrhotic patients and 40% of non cirrhotic HCV-infected patients had vitamin D deficiency. IL-23, IL-17, and MCP-1 were markedly increased in HCV-infected patients in comparison to controls.A significant negative correlation between vitamin D and IL-17 and-23 and MCP-1 was detected. HCV-infected males and females showed no differences with respect to viral load, vitamin D levels, IL-17, IL-23 and MCP-1. The viral load was negatively correlated with vitamin D and active vitamin D (P = 0.0001 and P = 0.001, respectively), while positively correlated with IL-23, IL-17, and MCP-1. We classified the patients according to sonar findings into four groups. Group Ⅰa with bright hepatomegaly and included 14 patients. Group Ⅰb with perihepatic fibrosis and included 11 patients. Group Ⅰc with liver cirrhosis and included 11 patients. Group Ⅰd with he patocellular carcinoma (HCC) and included 14 patients. Vitamin D and active vitamin D were shown to be lower in cirrhotic patients and much lower in patients with HCC, and this difference was highly significant (P = 0.0001). IL-17 and-23 and MCP-1 were higher in advanced liver disease) and the differences were highly significant (P = 0.0001).CONCLUSION:Whether the deficiency of vitamin D is related to HCV-induced chronic liver disease or predisposing factor for higher viral load is a matter of debate. | Noha M El Husseiny Hala M Fahmy Waleed A Mohamed Hisham H Amin | 2012 | World Journal of Hepatology2012，4，8： | 12 |
| 4 | FROM A SYSTEMIC APPROACH IN TEACHING AND LEARNING CHEMISTRY (SATLC) TO BENIGN ANALYSIS显示文摘 | A. F. M. Fahmy M. S. A. Hamza H. A. A. Medien W.G. Hanna M. Abdel-Sabour J. J. Lagowski | 2002 | 化学教育2002，23，12： | 9 |
| 5 | Screening pre-bariatric surgery patients for esophageal disease with esophageal capsule endoscopy显示文摘AIM:To determine if esophageal capsule endoscopy(ECE)is an adequate diagnostic alternative to esophagogastroduodenoscopy(EGD)in pre-bariatric surgery patients.METHODS:We conducted a prospective pilot study to assess the diagnostic accuracy of ECE(PillCam ESO2,Given Imaging)vs conventional EGD in pre-bariatric surgery patients.Patients who were scheduled for bariatric surgery and referred for pre-operative EGD were prospectively enrolled.All patients underwent ECE followed by standard EGD.Two experienced gastroenterologists blinded to the patient’s history and the findings of the EGD reviewed the ECE and documented their findings.The gold standard was the findings on EGD.RESULTS:Ten patients with an average body mass index of 50 kg/m2were enrolled and completed the study.ECE identified 11 of 14(79%)positive esophageal/gastroesophageal junction(GEJ)findings and 14of 17(82%)combined esophageal and gastric findings identified on EGD.Fisher’s exact test was used to compare the findings and no significant difference was found between ECE and EGD(P=0.64 for esophageal/GEJ and P=0.66 for combined esophageal and gastric findings respectively).Of the positive esophageal/GEJ findings,ECE failed to identify the following:hiatal hernia in two patients,mild esophagitis in two patients,and mild Schatzki ring in two patients.ECE was able to identify the entire esophagus in 100%,gastric cardia in0%,gastric body in 100%,gastric antrum in 70%,pylorus in 60%,and duodenum in 0%.CONCLUSION:There were no significant differences in the likelihood of identifying a positive finding using ECE compared with EGD in preoperative evaluation of bariatric patients. | Ashish Shah Erica Boettcher Marianne Fahmy Thomas Savides Santiago Horgan Garth R Jacobsen Bryan J Sandler Michael Sedrak Denise Kalmaz | 2013 | World Journal of Gastroenterology2013，19，37： | 7 |
| 6 | Wilsons 疾病作为尖锐胰腺炎,胆管炎,和黄疸介绍的诊断挑战显示文摘 Wilson’s disease is a rare disorder of copper transport in hepatic cells,and may present as cholestatic liver disease;pancreatitis and cholangitis are rarely associated with Wilsons’s disease.Moreover,cases of Wilson s disease presenting as pigmented gallstone pancreatitis have not been reported in the literature.In the present report,we describe a case of a 37-year-old man who was admitted with jaundice and abdomina pain.The patient was diagnosed with acute pancreatitis,cholangitis,and obstructive jaundice caused by pigmented gallstones that were detected during retrograde cholangiopancreatography.However,because of his long-term jaundice and the presence of pigmented gallstones,the patient underwent further evaluation for Wilson’s disease,which was subsequently confirmed.This patient’s unique presentation exemplifies the overlap in the clinical and laboratory parameters of Wilson’s disease and cholestasis,and the difficulties associated with their differentiation.It suggests thatWilson’s disease should be considered in patients with pancreatitis,cholangitis,and severe protracted jaundice caused by pigmented gallstones. | Elchanan Nussinson Azmi Shahbari Fahmi Shibli Elena Chervinsky Philippe Trougouboff Arie Markel | 2013 | World Journal of Hepatology2013，5，11： | 5 |
| 7 | HBV vaccine efficacy and detection and genotyping of vaccineé asymptomatic breakthrough HBV infection in Egypt显示文摘AIM:To evaluate the impact of mass vaccination against the hepatitis B virus (HBV) in Egypt,and to search for vaccinee asymptomatic breakthrough HBV infection and its genotype.METHODS:Seven hundred serum samples from vaccinated children and adults (aged 2-47 years) were used for quantitative and qualitative detection of HBsAb by ELISA.Three hundred and sixty serum samples representing undetectable or low or high HBsAb were screened for markers of active HBV infection (HBsAg,HBcAb (IgG) and HBeAb by ELISA,plus HBsAg by AxSYM) and HBV-DNA genotyping by nested multiplex PCR and by DNA sequencing.RESULTS:It was found that 65% of children aged 2-4 years,and 20.5% aged 4-13 years,as well as 45% adults were good responders to HBV vaccination mounting protective level HBsAb.Poor responders were 28%,59.5% and 34%,and non-responders were 7%,20% and 21% respectively,in the three studied groups.Markers of asymptomatic HBV infections were HBsAg detected by ELISA in 2.5% vs 11.39% by AxSYM.Other markers were HBcAb (IgG) in 1.38%,HBeAb in 0.83%,and HBV-DNA in 7.8%.All had HBV genotype E infection.CONCLUSION:It is concluded that HBV vaccine is efficient in controlling HBV infection among children and adults.The vaccine breakthrough infection was by HBV genotype E.A booster dose of vaccine is recommended,probably four years after initial vaccination. | Eman AE Abushady Magda MA Gameel John D Klena Salwa F Ahmed Kouka SE Abdel-wahab Sanya M Fahmy | 2011 | World Journal of Hepatology2011，3，6： | 5 |
| 8 | Research on experiment and calculation of foam bursting device显示文摘This research presents experimental data on mechanical foam bursting device,based on the high speed of air fluid impinging insidethe foam bursting device,foam bubbles disrupted as a consequence of pressures changed very quickly as shear force and their impact forces.Experimental data on foam-bursting capacity have been presented.Designed device can provide effective foam bursting on collapse foam. | Hazaea Mohammed Youhong SUN Ould El HousseinYarbana Longxiang XU Al-Aswar Fahmi | 2007 | Global Geology2007，10，1： | 5 |
| 9 | ON SOURCE ANALYSIS BY WAVE SPLITTING WITH APPLICATIONS IN INVERSE SCATTERING OF MULTIPLE OBSTACLES显示文摘我们学习为声学或电磁的散布问题切开过程的波浪。过程是切开一些的这些的想法散布了地进来自不同空间区域的地的和以便这个信息能为倒置算法或为活跃噪音控制被使用。切开算法能基于一般边界层潜力表示或格林的表示公式。我们将关于不同参考领域 G 在指定参考领域 G 和远地的模式的唯一的分解外面证明散布波浪的唯一的分解。进一步,我们与二为 scatterer 为地重建采用切开的技术或更多分开部件,由把它与为波浪恢复的点来源方法相结合。用散布波浪以及它的远地的模式的分解,切开过程的波浪在这建议纸在障碍,引起远地的模式的多重障碍能独立从被重建附近把一个有效方法给散布波浪的计算。这更加在反的散布的区域扩大分解方法的范围。最后,我们将提供数字例子表明切开的方法的可行性。 | Fahmi ben Hassen Jijun Liu Roland Potthast | 2007 | Journal of Computational Mathematics2007，25，3： | 4 |
| 10 | Liver stiffness as a predictor of hepatocellular carcinoma behavior in patients with hepatitis C related liver cirrhosis显示文摘Background: Risk strati cation and prognostication of hepatocellular carcinoma (HCC) help to improve patient outcome. Herein we investigated the role of liver stiffness measurement (LSM) in the prediction of HCC behavior. Methods: Totally 121 na ve patients with HCC were included. HCC radiological evaluation and staging were done. LSM was measured using virtual touch quanti cation. Patients were divided into early to intermediate HCC (BCLC-0, A and B) and late HCC (BCLCC and D). HCC was treated according to the BCLC stage. HCC recurrence-free interval was estimated. Results: The mean LSM inside the tumor was signi cantly lower than the peri-tumoral area and the cirrhotic non-cancerous liver parts (P<0.001). In late HCCs stage, the mean LSM inside the tumor and in the peri-tumoral tissue was lower than the corresponding values in the early to intermediate HCCs stage (P<0.001). LSM inside the tumor and in the peri-tumoral tissue negatively correlated with serum AFP, tumor vascular invasion, and stage (P<0.05). The recurrence-free interval was directly correlated to LSM inside the tumor and inversely to LSM in cirrhotic non tumorous liver part. Kaplan-Meier analysis showed that the recurrence-free interval was signi cantly longer in patients with LSM inside the tumor of ≥1.25m/s compared to those with LSM inside the tumor of<1.25m/s. Conclusions: LSM can serve as a potential non-invasive predictor for HCC clinical behavior and the recurrence-free interval following loco-regional treatments. | Sameh A Lashen Mohamed M Elshafei Fahmy H Hablass Eman A Alsayed Asmaa A Hassan | 2020 | Hepatobiliary & Pancreatic Diseases International2020，19，1： | 4 |
| 11 | 紫荆叶提取物对酪氨酸酶活性抑制作用的谱效关系研究显示文摘目的:研究紫荆叶提取物对酪氨酸酶活性抑制作用的谱效关系。方法:取不同采收时期的紫荆叶样品16批,以70%乙醇进行加热提取。采用高效液相色谱法对紫荆叶提取物进行分析,色谱柱为InertSustain C_(18),流动相为甲醇-0.1%冰醋酸溶液(梯度洗脱),流速为0.8 mL/min,柱温为30℃,检测波长为254 nm,进样量为10μL。将所获得的16个批次紫荆叶提取物色谱图采用《中药色谱指纹图谱相似度评价系统2004(A版)》进行匹配,获得量化特征色谱图并确定共有峰。采用体外酪氨酸酶多巴速率氧化微量法测定紫荆叶提取物对酪氨酸酶活性的抑制率。采用偏最小二乘回归分析法,以紫荆叶提取物特征共有峰峰面积为自变量、其对酪氨酸酶活性的抑制率为因变量进行谱效关系分析,筛选出与酪氨酸酶活性抑制作用有显著相关性的色谱峰。结果与结论:匹配得到紫荆叶提取物的16个特征共有峰;酪氨酸酶活性抑制试验结果显示,紫荆叶提取物质量浓度为100 mg/mL(按生药计)时对酪氨酸酶活性的抑制作用最强;谱效关系分析结果显示,紫荆叶提取物特征色谱图中P5、P8、P10、P12、P15、P16号共有峰与其对酪氨酸酶活性的抑制作用呈正相关(相关系数R>0.1),P2、P4号共有峰与其对酪氨酸酶活性的抑制作用呈负相关(相关系数绝对值│R│>0.1),提示上述特征共有峰代表的化合物可能对酪氨酸酶活性具有抑制或激活作用。 | 孙慧玲 何楠 史梦珺 Adel Fahmi Ahmed 李昌勤 | 2018 | 中国药房2018，29，24： | 4 |
| 12 | Airborne fine particulate matter induced pulmonary inflammation as well as oxidative stress in neonate rats显示文摘背景在空中的好微粒物质(下午) 能导致可以不利地影响人的健康的肺的发炎,但是关于它出生不满一月的婴儿老鼠上的效果的很少的报告是可得到的。这研究试图在出生不满一月的婴儿 rats.Methods 在航线上观察好下午的潜在的影响和毒性象氧化剂产品一样的肺的发炎, cytotoxicity,组织病理学说,和抗氧化剂被估计在 intratracheal 灌输以后的 24 个小时连续地罚款首相 3 天。好下午的 Cytotoxicity 在与发达重要肺的发炎由 neutrophiland 巨噬细胞渗入描绘了的高剂量罚款下午一起对待的 Hep-2 cells.Results 老鼠被测量。煽动性的过程在肺与 TNF- 和 prooxidant/antioxidant 不平衡的提高的水平有关。在人的上皮的房间执行的 Cytotoxicity 研究显示那位高剂量罚款首相显著地减少了学习表明了的房间 viability.Conclusion 罚款首相的尖锐暴露导致了航线发炎以及在航线上皮房间上除了它的直接有毒的效果增加了氧化应力。 | DING Li-ren WANG Kai Baher Fahmy SHEN Hua-hao Cormier Stephania | 2010 | Chinese Medical Journal2010，，20： | 4 |
| 13 | Fulminant hepatic failure caused by Salmonella paratyphi A infection显示文摘我们报导暴发性的肝的失败的一个案例把感染与沙门氏菌 paratyphi 联系了,在进入有二天的发烧的特别护理单位(ICU ) 的一个 29 岁的病人,头疼并且呕吐列在后面由行为变化和丧失方向感。在检查上,病人显得尖锐地病了,鼓动,糊涂,并且深深地 jaundiced。C 的温度 38.5 度,脉搏 92/min,血压 130/89 毫米汞柱。血的两件样品种了 S。paratyphi A,它对 ceftriaxone 和 ciprofloxacin 敏感。Ceftriaxon 与高剂量的地塞米松被管理。有 ceftriaxon 的二星期术后疗法,病人处于令人满意的状况被解除。 | Fahmi Yousef Khan Ahmed A Kamha Ibrahim Y Alomary | 2006 | World Journal of Gastroenterology2006，12，32： | 3 |
| 14 | 反复使用抗生素患者结膜菌群的变化及耐药模式研究(英文)显示文摘目的:观察和分析反复使用抗生素患者结膜菌群的变化。此外,确定这种反复暴露对结膜菌群抵抗模式的影响。方法:研究纳入40例眼科研究所视网膜科患者。所有受试者至少进行了连续4次、每月一次的玻璃体腔注射(IVI),其中一些患者根据需要延长至6mo或1y。将患者随机分为3组,每组给予氧氟沙星、莫西沙星或头孢他啶任意一种抗生素。使用Kirby-Bauer扩散法对所有细菌进行药敏试验。结果:研究中,以表皮葡萄球菌(51.2%)为主,其次是金黄色葡萄球菌(14%),微球菌(12.8%)和其他凝固酶阴性葡萄球菌(CONS)占13%。结果显示,在4次随访中,与随机接受头孢他啶治疗的患者的基线培养相比,接受头孢他啶治疗的患者眼部表皮葡萄球菌的百分比有所增加。相比之下,与基线相比,金黄色葡萄球菌的百分比没有明显增加。在氟喹诺酮治疗眼中观察到表皮葡萄球菌的百分比从基线增加。与头孢他啶治疗组相比,氟喹诺酮治疗组的金黄色葡萄球菌百分比较基线升高。然而,随着新一代和老一代氟喹诺酮类药物的暴露,眼部菌群组成模式发生了变化。我们注意到,从基线开始,莫西沙星治疗组比氧氟沙星治疗组的表皮葡萄球菌增多。暴露于老一代和新一代氟喹诺酮类药物的金黄色葡萄球菌的模式没有差异。结论:反复使用眼用抗生素不仅会改变正常眼部菌群的组成,还会选择耐药菌株。 | Rania Abdelmonem Khattab Maha Abdelfattah Iman Fahmy | 2019 | 国际眼科杂志2019，19，11： | 2 |
| 15 | 百合花脂溶性成分分析显示文摘[目的]分析百合花中挥发性成分。[方法]采用气相色谱-质谱联用技术(GC-MS),结合保留指数法并用峰面积归一化法测定相对百分含量。[结果]百合花中鉴定出9个挥发性成分,占总峰面积的38.01%。[结论]百合花中主要成分为亚油酸(8.93%)、n-棕榈酸(7.20%)、顺-1,3-二甲基环戊烷(6.83%)及1,2-二甲基环戊烷(5.47%)等。 | 王鹏禹 焦瑶歌 张京华 王迎利 Adel Fahmi Ahmed 康文艺 马常阳 | 2018 | 河南大学学报(医学版)2018，37，2： | 2 |
| 16 | Adult Klebsiella pneumoniae meningitis in Qatar:clinical pattern of ten cases显示文摘Objective:To describe the clinical presentation,underlying diseases,antimicrobial susceptibility,treatment and outcome of Klebsiella pneumoniae meningitis patients.Methods:This retrospective study involved all patients with 15 years of age or older who admit ted to Hamad General Hospital with culture proven Klebsiella pneumoniae meningitis from January 1,2007 to December 31,2012.Results:A total of ten cases were identified mine males and one female).Their mean age was i43.3±12.8) years.Eight patients(80%) had nosocomial meningitis with neurosurgery being the most frequent associated condition.Fever and altered consciousness were the most frequent symptom.Cerebrospinal fluid showed elevated protein and glucose levels.Oram slain showed Gram—negative rods in 50%of cases,while positive cerebrospinal fluid culture results were found in all patients.Multidrug resistance was observed in two cases,and all patients had received appropriate empirical and definitive antibiotic treatments.The mean duration of intravenous antimicrobial treatment was(19.3±7.0) d and all patients with external ventricular drains underwent removal of the device,while in—hospital mortality was 50%.Conclusions:The number of cases was too small to come up with therapeutic and prognostic conclusions.Further large-scale prospective study is needed. | Fahmi Yousef Khan Mohammed Abukhattab Mohanuned Abukamar Deshmukh Anand | 2014 | Asian Pacific Journal of Tropical Biomedicine2014，4，8： | 2 |
| 17 | Development of an effective process for utilization of collagen from livestock and fish waste显示文摘 | S Morimura H Nagata Y Uemura A Fahmi T Shigematsu K Kida | 2002 | Process Biochemistry2002，，12： | 2 |
| 18 | 纳米结构Al-Cu合金室温和高温力学性能的无损评价(英文)显示文摘研究工艺参数对纳米结构Al-10wt.%Cu合金力学性能的影响。用应力-应变Microprobe®系统(SSM)和自动球压痕仪(ABI®)评估合金的力学性能。对于球磨6 h、球料比(BPR)分别为30:1和90:1条件下制备的样品,测试温度为21℃。此外,还对球料比为90:1球磨后制备的样品分别在200和400℃下进行高温测试。结果表明,球料比增加导致最终压痕载荷从(316±26)N增加到(631±9)N,压痕深度从111μm减小到103μm。对于球料比为90:1制备的样品,测试温度从21℃升高到400℃,导致最终载荷从(631±9)N降低到(125±1)N,最终压痕深度从103μm降低到(116±1)μm。在所有测试样品中,球料比为90:1制备的样品,当测试温度为21℃时表现出最高的强度和最低的变形能力,而测试温度为400℃时表现出最低的强度和最高的变形能力。 | Hany R.AMMAR Fahmy MHAGGAG | 2019 | Transactions of Nonferrous Metals Society of China2019，29，12： | 2 |
| 19 | Calcium channel α2δ1 subunit as a novel biomarker for diagnosis of hepatocellular carcinoma显示文摘Objective:Hepatocellular carcinoma(HCC)is the fifth most common malignancy worldwide.The identification of new simple,inexpensive and highly accurate markers for HCC diagnosis and screening is needed.This case-control study evaluates the role of annexin A2 and voltage-gated calcium channelsα2δ1 subunit as serum biomarkers for HCC diagnosis.Methods:The study comprised three groups:group 1,50 patients with an initial diagnosis of HCC associated with chronic hepatitis C virus infection;group 2,25 patients diagnosed with chronic hepatitis C virus infection and cirrhosis without any evidence of HCC;and group 3,15 healthy controls.All participants were subjected to clinical and laboratory investigations,and radiological scanning.The serum levels of alpha-fetoprotein(AFP),annexin A2,and theα2δ1 subunit were evaluated by using ELISA technique.Results:The serum levels of annexin A2 significantly increased in patients with HCC(10.4±2.5 ng/m L;P<0.001)or with cirrhosis(9.31±1.8 ng/m L;P<0.001)comparing to that of healthy controls(0.296±0.09 ng/m L).However,there was no significant difference in serum annexin A2 levels in patients with HCC comparing to those with cirrhosis.Serumα2δ1 subunit significantly increased in patients with HCC(20.12±3.7 ng/m L)comparing to that in patients with cirrhosis(10.41±3.4 ng/m L,P<0.001)and healthy controls(10.2±2.9 ng/m L,P<0.001).Conclusions:The serumα2δ1 subunit may function as a new biomarker for HCC diagnosis.Conversely,serum annexin A2 has low diagnostic value as an HCC marker,especially in patients with underlying cirrhosis. | Sana Amhimmid Badr Maryan Waheeb Fahmi Manal Mahmoud Nomir Mamdouh Mohammad El-Shishtawy | 2018 | Cancer Biology & Medicine2018，15，1： | 2 |
| 20 | Semen parameters in men with spinal cord injury: changes and aetiology显示文摘瞄准:为了与针的绳索损害(SCI ) 和这些的可能的原因在人在精液参数估计变化,变化。方法:学习与 SCI 包括了 45 个题目。精液检索被手淫(2 ) 做,精力旺盛的职业人员静电干扰按摩(n = 13 ) ,阴茎振动刺激(n = 13 ) 或电镀物品射精(n = 17 ) 。结果:有 SCI 的人的精液显示出正常体积( 2.3 ± 1.9 mL )并且精子计数( 85.0 × 10 ~ 6 ± 83.8 × 10 ~ 6/mL )与减少的活动性(11.6%± 10.1%),活力(18.5%± 15.2%)并且正常形式( 17.5 ± 13.4%),并且脓房间被增加了( 6.0 × 10 ~ 6 ± 8.2 × 10 ~ 6/mL )。全部(13.4 ± 9.9 对 7.1 ± 6.8 ) 并且进步(4.4 ± 3.9 对 2.2 ± 2 .1 ) 活动性在有更低的阴囊的温度的题目是显著地更高的。关于任何精液参数电镀物品射精和阴茎振动刺激组之间没有统计重要差别。题目的年龄,很少发生的射精,损害持续时间和神经质的侧面没在精液参数上显示出重要效果。结论:在有 SCI 的人的 seminogram 的定义特征是正常体积并且与减少的精子活动性,活力和正常数形式,和脓房间的增加的数字。精液的恶化的最可接受的原因被提高阴囊的温度。 | Mohamed N. Momen Ibrahim Fahmy Medhat Amer Mohamad Arafa Wael Zohdy Taha A. Naser | 2007 | Asian Journal of Andrology2007，9，5： | 2 |
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