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| 1 | Predictability of outcome of caustic ingestion by esophagogastroduodenoscopy in children显示文摘AIM: To assess the necessity of esophagogastroduodenoscopy (EGD) to predict the outcome of caustic ingestion in children. METHODS: The study included 206 children who underwent EGD because of ingestion of caustic substances between January 2005 and August 2010. Retrospective analysis of data of the patients was performed. RESULTS: The male/female ratio was 1.6 and mean age was 38.1 ± 28.8 mo. The caustic substances were acidic in 72 (34.9%) cases, alkaline in 56 (27.2%), liquid household bleach in 62 (30.1%), and unknown in 16 (7.8%). Fifty-seven (27.7%) patients were symptom-free. Significant clinical findings were observed in 149 (72.3%) patients. Upper gastrointestinal endoscopy findings of esophageal injury were grade 0 in 86 (41.7%) patients, grade 1 in 49 (23.8%), grade 2a in 42 (20.4%), grade 2b in 28 (13.6%), and grade 3a in 1 (0.5%) patient. 35 patients with grade 2a, 2b, and 3a injuries underwent esophageal dilation at second week of ingestion. Esophageal stricture, which necessitated a regular dilation program developed in 13 of the aforementioned 35 patients. There is no statistically significant difference in the rate of development of esophageal stricture between the patients who ingested acidic (15.3%) and alkaline (8.9%) substances (P = 0.32). Severe gastric injury was detected in 38 (18.5%) patients. The rate of development of gastric injury was significantly higher in the acidic group (14%) than in the alkaline group (2.9%) (P = 0.001). Out of 149 patients with clinical findings, 49 (32.9%) patients had no esophageal injury and 117 (78.5%) patients had no gastric lesion. Esophageal and severe gastric injuries were detected in 20 (35.1%) and 8 (14%) of patients with no clinical findings respectively. Pyloric stenosis developed in 6 patients. Pyloric obstruction improved with balloon dilation in 2 patients. Mean hospitalization time were 1.2 ± 0.5 d for grade 0 and 2.3 ± 5 d for grade 1 and 6.3 ± 6.2 d for grade 2a and 15.8 ± 18.6 d for grade 2b. It was significantly longer for patients with grade 2a and 2b injuries (P = 0.000). CONCLUSION: Endoscopy is an effective technique for determining the presence of esophageal and gastric damage and to avoid unnecessary treatment in patients with no or mild injury. | Abdulkerim Temiz Pelin Oguzkurt Semire Serin Ezer Emine Ince Akgun Hicsonmez | 2012 | World Journal of Gastroenterology2012，18，10： | 8 |
| 2 | Reaching proficiency in laparoscopic splenectomy显示文摘AIM:To investigate the proficiency level reached in laparoscopic splenectomy using the learning curve method.METHODS:All patients in need of splenectomy for benign causes in whom laparoscopic splenectomy was attempted by a single surgeon during a time period of 6 years were included in the study (n=33). Besides demographics, operation-related variables and the response to surgery were recorded. The patients were allocated to groups of five, ranked according to the date of the operation. Operation duration, complications, postoperative length of stay, conversion to laparotomy and splenic weight were then compared between these groups.RESULTS: There was a significant difference regarding operation times between the groups (P = 0.001). An improvement was observed after the first 5 cases. The learning curve was flat up to the 25th case. Following the 25th case the operation times decreased still further. There was no difference between the groups regarding the other parameters.CONCLUSION: Unlike the widely accepted 'L' shape, the learning curve for laparoscopic splenectomy is a horizontal lazy 'S' with two distinct slopes. Privileges may be granted after the first 5 cases. However proficiency seems to require 25 cases. | Tarik Zafer Nursal Ali Ezer Sedat Belli Alper Parlakgumus Kenan Caliskan Turgut Noyan | 2009 | World Journal of Gastroenterology2009，15，32： | 3 |
| 3 | Cell surface enzyme attachment is mediated by family 37 carbohydrate binding modules, unique to Ruminococcus albus显示文摘 | Ezer A Eerz M Jindoa S | 2008 | Journal Bacheriol2008，190，24： | 1 |
| 4 | Design and performance of a zero-discharge tilapia recirculating system显示文摘 | Nadav Shnel Yoram Barak Tamir Ezer | 2002 | Aquacult Eng2002，26，3： | 1 |
| 5 | The Tabby phenotype is caused by mutation in a mouse homologue of the EDA gene that reveals novel mouse and human exons and encodes a protein (ectodysplasin-A) with collagenous domains显示文摘 | Srivastava AK Pispa J Hartung AJ Du Y Ezer S Jenks T | 1997 | Proc Natl Acad Sci USA1997，94，13： | 1 |
| 6 | Differential expression of Tie-2 receptors and angiopoietins in response to in vivo hypoxia in rats 显示文摘 | Abdulmalek K Ashur F Ezer N | 2001 | Am J Physiol Lung Cell Mol Physiol2001，281，3： | 1 |
| 7 | Hurricane-induced motions and interaction with ocean currents 显示文摘 | Dey L Y Ezer T Wang D P | 2007 | Cont Shelf Res2007，27，： | 1 |
| 8 | Developments in terrain-following ocean models: intercomparisons of numerical aspects 显示文摘 | EZER T ARANGO H G SHCHEPETKIN A F | 2002 | Ocean Modelling2002，6，4： | 1 |
| 9 | Anhidrotic ectodermal dysplasia (EDA) protein expressed in MCF-7 cells associated with cell membrane and induces rounding显示文摘 | Sini Ezer David Schlessinger | 1997 | Hum Mol Genet1997，6，： | 1 |
| 10 | The anhidrotic ec- todermal dysplasia gene (EDA) undergoes alternative splicing and encodes ectodysplasin - A with deletion mutations in collagenous repeats显示文摘 | Bayes M Hartung AJ Ezer S | 1998 | Hum Molec Gen- et1998，7，： | 1 |
| 11 | Magnetic-field-induced strains in polycrystalline Ni-Mn-Ga at room temperature 显示文摘 | Ezer Y Sozinov A | 2001 | Scripta Mater2001，44，： | 1 |
| 12 | Sea level variations induced by heating and cooling:an evaluation of the boussinesq approximation in ocean models显示文摘 | MELLOR G L EZER T | 1995 | J Geophys Res1995，100，20： | 1 |
| 13 | Design and performance of a zero- discharge tilapia recirculating system 显示文摘 | SHNEL N BARAK Y EZER T | 2002 | Aquac Eng2002，26，： | 1 |
| 14 | The pressure gradient conundrum of sigma coordinate ocean models显示文摘 | MELLOR G L EZER T OEY L Y | 1994 | J Atmos Oceanic Technol1994，11，1： | 1 |
| 15 | Magnetic-field-induced strains in polycrystalline Ni-Mn-Ga at room temperature显示文摘 | ULLAKKO K EZER Y SOZINOV A KIMMEL G YAKOVENKO P LINDROOS V K | 2001 | Scripta Mater2001，44，3： | 1 |
| 16 | The pressure gra- dient conundrum of sigma coordinate ocean models显示文摘 | MELLOR G L EZER T OEY L Y | 1994 | Journal of Atmospheric and Oceanic Technology1994，11，4： | 1 |
| 17 | Clinical outcomes of manual bowel decompression (milking) in the mechanical small bowel obstruction: a prospective randomized clinical tri-al显示文摘 | Ezer A Torer N Colakoglu T | 2012 | Am J Surg2012，203，1： | 1 |
| 18 | Assessment of the neuropeptide S system in anxiety disorders 显示文摘 | Donner J Haapakoski R Ezer S | 2010 | Biol Psychiatry2010，68，47： | 1 |
| 19 | Perianal abscess and fistula-inano in children:aetiology,management and outcome显示文摘 | Ezer SS Oguzkurt P Ince E | 2010 | J Paediatr Child Health2010，46，3： | 1 |
| 20 | Primary vaginal calculus secondary to urethrovaginal fistula with imperforate hymen in a 6-year-old girl显示文摘 | Pelin Oguzkurt Emine Ince Semire Serin Ezer Abdülkerim Temiz Senay Demir Akgun Hicsonmez | 2009 | Journal of Pediatric Surgery2009，，7： | 1 |
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