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| 1 | Retinal nerve fiber layer thickness changes in obstructive sleep apnea syndrome: one year follow-up results显示文摘·AIM: To investigate the retinal nerve fiber layer(RNFL)thickness changes in patients with obstructive sleep apnea syndrome(OSAS) for one year follow-up. To discuss the possibility of detecting tendency of glaucoma in this population by using spectral domain optical coherence tomography(3D-OCT-2000 Spectral domain).·METHODS: After polysomnographic study, all subjects(64 OSAS patients and 40 controls) underwent detailed ophthalmological examination. After these examinations,patients with glaucoma and patients who had ophthalmological and/or systemic disease were excluded from the study.Totally, 20 patients in OSAS group and five patients in controls were excluded from the study in the first examination and follow-up period. The RNFL thickness was assessed with OCT. Forty-four OSAS patients and 35 control subjects were followed up for12 mo. RNFL thickness change and OSAS patients were evaluated for severity of disease by Apnea-Hypopnea Index(AHI).·RESULTS: Forty-four OSAS patients and 35 controls were enrolled in the study. Statistically significance was found between OSAS patients and controls at the 12 thmo.Average RNFL thickness was found to be significantly lower in last measurements in OSAS patients when compared with first measurements and control subjects(P <0.001, 0.002, respectively). There was a statistically significant correlation among AHI, and RNFL thickness(P <0.05).·CONCLUSION: The results suggest that the patients with OSAS were related with a proportional decrease in the RNFL thickness. These patients should be followed up regularly for glaucomatous changes. Detecting more RNFL thinning in severe OSAS was important. | Mehmet Ozgur Zengin Ibrahim Tuncer Eyyup Karahan | 2014 | International Journal of Ophthalmology(English edition)2014，7，4： | 9 |
| 2 | Evaluation of systemic risk factors in different optical coherence tomographic patterns of diabetic macular edema显示文摘● AIM: To elucidate the relationship between systemic risk factors and different patterns of diabetic macular edema(DME) determined with optical coherence tomography(OCT).● METHODS: In this cross-sectional study, DME was classified by OCT as diffuse retinal thickness(DRT), cystoid macular edema(CME) and serous retinal detachment(SRD) and the relationship between the systemic risk factors and DME patterns was evaluated.● RESULTS: Of the 57 patients with DME, 21(36.8%) had DRT, 24(42.1%) had CME and 12(21.0%) had SRD. Microor macro-albuminuria was significantly higher in the DRT pattern(61.9%) compared with the SRD(50.0%) and CME patterns(25.0%; P=0.040). Hemoglobin A1 c(Hb A1 c) level was significantly higher and patients were younger in the DRT pattern group(P=0.034, P=0.032). Best corrected visual acuity was the worst and central macular thickness was the thickest in the CME pattern group.● CONCLUSION: Micro-or macro-albuminuria may be more frequent and Hb A1 c level may be higher in patients with DRT. These patients are also seen to be younger than patients with non-DRT. | Durgul Acan Eyyup Karahan Nilufer Kocak Suleyman Kaynak | 2018 | International Journal of Ophthalmology(English edition)2018，11，7： | 5 |
| 3 | Comparison of the Retinomax hand-held autorefractor versus table-top autorefractor and retinoscopy显示文摘AIM:To compare noncycloplegic and cycloplegic results of Retinomax measurements with findings achieved after cycloplegia using table-top autorefractor and retinoscopy.METHODS:The study included 127 patients(mean age96.7mo,range 21 to 221).Retinomax(Rmax)(Nikon Inc.,Japan)was used to obtain noncycloplegic refraction.Under cycloplegia,refraction was measured with Rmax,table-top autorefractor(TTR)(Nikon NRK 8000,Inc.,Japan)and retinoscopy.The values of sphere,spherical equivalent,cylinder and axis of cylinder were recorded for Rmax,TTR and retinoscopy in each eye.All results were analyzed statistically.RESULTS:The mean spheric values(SV),spherical equivalent values(SEV)and cylindrical values(CV)of the noncycloplegic Rmax(SV:0.64 D,SEV:0.65 D and CV:0.03 D,respectively)were found to be significantly lower than cycloplegic TTR(1.43 D,1.38 D and 0.3 D;P=0.012,P=0.011 and P=0.04,respectively)and retinoscopy(1.34 D,1.45 D and 0.23 D;P=0.04,P=0.002 and P=0.045,respectively).Mean cycloplegic SV,SEV,CV were not significantly different between Rmax and TTR,Rmax and retinoscopy,TTR and retinoscopy.Cycloplegic or noncycloplegic axis values were not different between any method.CONCLUSION:Rmax may be used successfully as a screening tool but may not be accurate enough for actual spectacle prescription.Cycloplegic Rmax measurements may be able to identify refractive error in children because of approximate results to retinoscopy. | Ibrahim Tuncer Mehmet Ozgur Zengin Eyyup Karahan | 2014 | International Journal of Ophthalmology(English edition)2014，7，3： | 3 |
| 4 | Spontaneous resolution of macular edema after silicone oil removal显示文摘AIM: To investigate the macular changes in eyes filled with silicone oil(SO) and course of these changes after SO removal. METHODS: A retrospective optical coherence tomography scan review was conducted for twenty-four patients who underwent uncomplicated pars plana vitrectomy with SO tamponade for complex retinal detachments were detected with optical coherence tomography before, and one week, one month and three months after SO removal.RESULTS: Mean duration of SO tamponade was 3.6±1.0mo(range 3-7mo). Cystoid macular edema(CME) was detected in 3 eyes before SO removal. Submacular fluid was represented in 1 eye before silicone SO removal.Resolution of CME and submacular fluid was achieved1 mo after SO removal in all eyes. Mean best corrected visual acuity(BCVA) was 1.15 ±0.65(range, hand movement to 0.2) before SO removal in the eyes without macular changes. After SO removal, the mean BCVA values at 1wk and 1 and 3mo, and 0.82 ±0.23, 0.76 ±0.21,and 0.70 ±0.19, all of which were significantly better than baseline(P =0.030, 0.017, 0.006 respectively). In the eyes with macular CME and subretinal fluid the mean BCVA was significantly improved at 3mo after SO removal compared with baseline(P =0.037).CONCLUSION: Decreased visual acuity in eyes filled with SO could be caused by macular complications due to SO. CME and subretinal fluid may resolve without any additional macular surgery after SO removal. | Eyyup Karahan Ibrahim Tuncer Mehmet Ozgur Zengin Cem Kucukerdonmez Suleyman Kaynak | 2014 | International Journal of Ophthalmology(English edition)2014，7，6： | 1 |
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