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11篇 您的检索式:作者名="Extremera N"
    题名 作者 年代 出处 被引量
1Self-reported emotional intel- ligence, burnout and engagement among staff in services for people with intellectual disabilities显示文摘DuraN A Extremera N Rey L 2004Psychological Reports2004,95,2:1
2Self-reported Emotional Intelligence, Burnout and Engagement Among Staff in Services for People with Intellectual Disabilities 显示文摘Duran A Extremera N Rey L 2004Psychological Reports2004,95,2:1
3Health-related quality of life and cognitive emotion regulation strategies in the unemployed: a cross-sectional survey显示文摘Extremera N Rey L 2014Health and Quality of Life Outcomes2014,12,1:1
4Emotional intelli- gence, life satisfaction and subjective happiness in female student health professionals: liae mediatiug effect of perceived stress 显示文摘Ruiz-Aranda D Extremera N Pineda-Galan C 2014J Psvchiatr Ment Health Nurs2014,21,2:1
5Emotional intelligence as predictor of mental, social, and physical health in university students 显示文摘EXTREMERA N FERNANDEZ-BERROCAL P 2006The Spanish Journal of Psychology2006,9,:1
6Self-reported Emotional Intelligence, Burnout and Engagement Among Staff in Services for People with Intellectual Disabilities 显示文摘Duran A Extremera N Rey L 2004Psychological Reports2004,95,2:1
7Synergistic cytotoxicity of the poly ( ADP ‐ribose) polymerase inhibitor ABT ‐888 and temozolomide in dual‐drug targeted magnetic nanoparticles显示文摘José A Mu?oz‐Gámez Julián López Viota Andrés Barrientos ángel Carazo Laura Sanjuán‐Nu?ez Rosa Quiles‐Perez Paloma Mu?oz‐de‐Rueda ángel Delgado ángeles Ruiz‐Extremera Javier Salmerón 2015Liver Int2015,,4:1
8Daily life activities as mediators of the relationship between personality variables and subjective well-being among older adults显示文摘González V Extremera N 2010Pers Individ Dif2010,49,1:1
9Perceived Emotional Intelligenceand Clinical Symptoms in Mental Disorders显示文摘Lizeretti NP Extremera N Rodriquez A 2012PsychiatricQuarterly2012,83,4:1
10Self-reported Emotional Intelligence, Burnout and Engagement Among Staff in Services for People with Intellectual Disabilities 显示文摘Duran A Extremera N Rey L 2004Psychological Reports2004,95,38:1
11Hepatitis C virus NS5A region mutation in chronic hepatitis C genotype 1 patients who are non-responders to two or more treatments and its relationship with response to a new treatment显示文摘AIM To determine the number of mutations in the NS5 A region of the hepatitis C virus(HCV) and its relationship to the response to antiviral therapy in patients with chronic hepatitis C genotype 1 who are non-responders to two or more treatments. METHODS Sequences within HCV NS5 A [PKR binding domain(PKRBD) and the interferon-sensitivity-determining region(ISDR)] were analysed via direct sequencing in a selected cohort of 72 patients, with a total of 201 treatments [interferon-alpha(IFN-α), n = 49; IFN-α + ribavirin(RBV), n = 75; pegylated(peg) IFN-α + RBV, n = 47; first-generation direct-acting antivirals(DAAs), n = 13; and second-generation DAAs, n = 17]. Of these, 48/201 achieved a sustained virological response(SVR) and 153/201 achieved no virological response(NVR).RESULTS For both regions, treatments resulting in SVR were associated with more baseline mutations than were treatments resulting in NVR(SVR vs NVR; PKRBD: 5.82 ± 3 vs 4.86 ± 2 mutations, P = 0.045; ISDR: 2.65 ± 2 vs 1.51 ± 1.7 mutations, P = 0.005). A decrease or no change in the number of mutations over time between treatments in the PKRBD or ISDR, as shown by sequencing, was associated with patients who usually failed to respond to treatment(PKRBD, P = 0.02; ISDR, P = 0.001). Moreover, patients showing a post-treatment baseline viral load > 600000 IU/m L and increased ISDR mutations with respect to the previous treatment were 9.21 times more likely to achieve SVR(P = 0.001). CONCLUSION The obtained results show that among patients who have shown no response to two or more antiviral treatments, the likelihood of achieving SVR increases with the genetic variability in the ISDR region(≥ 2 mutations or number of substitutions from the HCV-J and HCV-1 prototype), especially when the viral load is greater than 600000 IU/m L.Paloma Munoz de Rueda José Manuel Fuentes RodríguezRosa Quiles Pérez Ana Gila Medina Ana Belén Martínálvarez Jorge Casado Ruíz ángeles Ruíz Extremera Javier Salmerón 2017World Journal of Gastroenterology2017,23,25:0
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