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| 1 | Interprofessional, multiple step simulation course improves pediatric resident and nursing staff management of pediatric patients with diabetic ketoacidosis显示文摘AIM To investigate the use of a multidisciplinary, longitudinal simulation to educate pediatric residents and nurses on management of pediatric diabetic ketoacidosis.METHODS A multidisciplinary, multiple step simulation course was developed by faculty and staff using a modified Delphi method from the Pediatric Simulation Center and pediatric endocrinology department. Effectiveness of the simulation for the residents was measured with a pre- and post-test and a reference group not exposed to simulation. A follow up post-test was completed 3-6 mo after the simulation. Nurses completed a survey regarding the education activity. RESULTS Pediatric and medicine-pediatric residents(n = 20) and pediatric nurses(n = 25) completed the simulation course. Graduating residents(n = 16) were used as reference group. Pretest results were similar in the control and intervention group(74% ± 10% vs 76% ± 15%, P = 0.658). After completing the intervention, participants improved in the immediate post-test in comparison to themselves and the control group(84% ± 12% post study; P < 0.05). The 3-6 mo follow up post-test results demonstrated knowledge decay when compared to their immediate post-test results(78% ± 14%, P = 0.761). Residents and nurses felt the interdisciplinary and longitudinal nature of the simulation helped with learning.CONCLUSION Results suggest a multidisciplinary, longitudinal simulation improves immediate post-intervention knowledge but important knowledge decay occurs, future studies are needed to determine ways to decrease this decay. | Linnea M Larson-Williams Amber Q Youngblood Dawn Taylor Peterson J Lynn Zinkan Marjorie L White Hussein Abdul-Latif Leen Matalka Stephen N Epps Nancy M Tofil | 2016 | World Journal of Critical Care Medicine2016，5，4： | 4 |
| 2 | Trends in treatment and overall survival among patients with proximal esophageal cancer显示文摘BACKGROUND The management of proximal esophageal cancer differs from that of tumors located in the mid and lower part of the esophagus due to the close vicinity of vital structures.Non-surgical treatment options like radiotherapy and definitive chemoradiation(CRT)have been implemented.The trends in(non-)surgical treatment and its impact on overall survival(OS)in patients with proximal esophageal cancer are unclear,related to its rare disease status.To optimize treatment strategies and counseling of patients with proximal esophageal cancer,it is therefore essential to gain more insight through real-life studies.AIM To establish trends in treatment and OS in patients with proximal esophageal cancer.METHODS In this population-based study,patients with proximal esophageal cancer diagnosed between 1989 and 2014 were identified in the Netherlands Cancer Registry.The proximal esophagus consists of the cervical esophagus and the upper thoracic section,extending to 24 cm from the incisors.Trends in radiotherapy,chemotherapy,and surgery,and OS were assessed.Analyses were stratified by presence of distant metastasis.Multivariable Cox proportional hazards regression analyses was performed to assess the effect of period of diagnosis on OS,adjusted for patient,tumor,and treatment characteristics.RESULTS In total,2783 patients were included.Over the study period,the use of radiotherapy,resection,and CRT in non-metastatic disease changed from 53%,23%,and 1%in 1989-1994 to 21%,9%,and 49%in 2010-2014,respectively.In metastatic disease,the use of chemotherapy and radiotherapy increased over time.Median OS of the total population increased from 7.3 mo[95%confidence interval(CI):6.4-8.1]in 1989-1994 to 9.5 mo(95%CI:8.1-10.8)in 2010-2014(logrank P<0.001).In non-metastatic disease,5-year OS rates improved from 5%(95%CI:3%-7%)in 1989-1994 to 13%(95%CI:9%-17%)in 2010-2014(logrank P<0.001).Multivariable regression analysis demonstrated a significant treatment effect over time on survival.In metastatic disease,median OS was 3.8 mo(95%CI:2.5-5.1)in 1989-1994,and 5.1 mo(95%CI:4.3-5.9)in 2010-2014(logrank P=0.26).CONCLUSION OS significantly improved in non-metastatic proximal esophageal cancer,likely to be associated with an increased use of CRT.Patterns in metastatic disease did not change significantly over time. | Judith de Vos-Geelen Sandra ME Geurts Liselot BJ Valkenburg-van Iersel Evelien JM de Jong Vivianne CG Tjan-Heijnen Margreet van Putten Valery EPP Lemmens Heike I Grabsch Nadia Haj Mohammad Frank JP Hoebers Chantal V Hoge Paul M Jeene Hanneke WM van Laarhoven Tom Rozema Marije Slingerland Grard AP Nieuwenhuijzen | 2019 | World Journal of Gastroenterology2019，25，47： | 2 |
| 3 | Familiy Identity:A Framework of Identity Interplay in Consumption Pratices显示文摘 | Epp A M | 2008 | Journal of Consumer Research2008，35，1： | 1 |
| 4 | Two types of anthracnose resistance in cucumbers显示文摘 | Barnes W C Epps W M | 1952 | Plant Disease Reporter1952，36，： | 1 |
| 5 | Long-lived memory T lymphocyte responses after Hantavirus infection 显示文摘 | Terajima M Mustonen J | 2002 | J Exp Med2002，196，5： | 1 |
| 6 | Raising antibodies against OprD,an outer membrane protein of Pseudomonas aeruginosa using translational fusions to MalE显示文摘 | Epp S F Phechere J Kok M | 2001 | J Microbiol Meth2001，46，1： | 1 |
| 7 | Developing Profes- sional Skills in STEM Students: Data Information Literacy 显示文摘 | Sapp Nelson M R Zilinski L Van Epps A S | 2014 | Issues in Science and Technology Librarianship2014，，： | 1 |
| 8 | The stochastic dependence of security price changes and transaction volumes: Implications for the mixture of distributions hypothesis显示文摘 | Epps T W Epps M L | 1976 | Econometrica1976，44，： | 1 |
| 9 | An additional gene for resistance to soybean cyst nematode Heterodera glycines显示文摘 | Hartwig E E J M Epps | 1970 | Phytopathology 19701970，584，： | 1 |
| 10 | Comprehensive two- dimensional gas chromatography with isotope dilution time-of- flight mass spectrometry for the measurement of dioxins and polych- lorinated biphenyls in foodstuffs comparison with other methods显示文摘 | FOCANT J F EPPE G SCIPPO M L | 2005 | Journal of Chromatography A2005，1086，： | 1 |
| 11 | The stochastic dependence of security price changes and transaction volumes:implications for the mixture-of-distribution hypothesis 显示文摘 | Epps T W Epps M L | 1976 | Econometrica1976，44，： | 1 |
| 12 | Clinical intervention in tobacco control显示文摘 | Manley M Epps RP Husten C | 1991 | JAMA1991，266，22： | 1 |
| 13 | Morphological Variations in soybean cyst nematodes显示文摘 | Golden M Epps J M | 1965 | Nematolo-gica1965，1，38： | 1 |
| 14 | Carbapenem activities against Pseudomonas aeruginosa: respective contributions of OprD and efflux systems显示文摘 | Kohler T Michea-Hamzehpour M Epp SF | 1999 | Antimicrob Agents Chemother1999，43，2： | 1 |
| 15 | Powdery mildew resistance in south Carolina cucumbers 显示文摘 | BARNES W C EPPS W M | 1956 | Plant Dis Rptr1956，40，： | 1 |
| 16 | FOXE1 association with differentiated thyroid cancer and its progression显示文摘 | Penna-Martinez M Epp F Kahles H | 2014 | Thyroid2014，24，5： | 1 |
| 17 | Comprehensive two-di- mensional gas chromatography with isotope dilution time- of-flight mass spectrometry for the measurement of diox- ins and polychlorinated biphenyls in foodstuffscomparison with other methods显示文摘 | Focant J Eppe G Scippo M | 2005 | Journal of Chromatography A2005，1086，： | 1 |
| 18 | Terminology and identity of infraspecific forms of the soybean cyst nematode (Heterodera glycines) 显示文摘 | Golden A M Epps J M Riggs R D | 1970 | Plant Disease Reporter1970，54，： | 1 |
| 19 | Comparison of a novel lyera endotracheal tube cuff to standard polyvinyl chloride cuff and polyurethane cuff for fluid leak prevention 显示文摘 | Kolobow T Cressoni M Epp M | 2011 | Respir Care2011，56，8： | 1 |
| 20 | Terrestrial heat flow in the sea around the Nansei Shoto (Ryukyu Islands)显示文摘 | Yasui M Epp D Nagasaka K | 1970 | Tectonophysics1970，10，： | 1 |
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