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| 1 | Pre-operative factors that can predict neoplastic polypoid lesions of the gallbladder显示文摘AIM:To investigate the preoperative factors that can predict neoplastic polypoid lesions of the gallbladder(PLGs) as well as malignant PLGs.METHODS:A retrospective analysis was conducted on the 210 consecutively enrolled patients who underwent cholecystectomy due to a PLG larger than 10 mm,as was determined by preoperative trans-abdominal ultrasonography or endoscopic ultrasonography.We ana-lyzed the medical,laboratory,radiologic data and the pathologic results.RESULTS:In 210 cases,146 had non-neoplastic polyps(69.5%) and 64 cases were neoplastic polyps(30.5%).An older age(≥ 65 years),the presence of diabetes mellitus(DM) and the size of polyp(≥ 15 mm) were revealed to be independent predictive variables for neoplastic polyps with odd ratios(OR) of 2.27(P = 0.044),2.64(P = 0.021) and 4.94(P < 0.01),respectively.Among the neoplastic PLGs,an older age(≥ 65 years),the presence of DM and polyp size(≥ 15 mm) were associated with malignancy with ORs of 4.97(P = 0.005),6.13(P = 0.001) and 20.55(P < 0.001),respectively.CONCLUSION:Among patients with PLGs larger than 10 mm in size,higher risk groups such as elderly patients more than 65 years old,those with DM or a large polyp size(≥ 15 mm) should be managed by cholecystectomy. | Byung Hyo Cha Jin-Hyeok Hwang Sang Hyub Lee Jang Eon Kim Jai Young Cho Haeryoung Kim So Yeon Kim | 2011 | World Journal of Gastroenterology2011，17，17： | 27 |
| 2 | Favorable surgical treatment outcomes for chronic constipation with features of colonic pseudo-obstruction显示文摘AIM:To determine long-term outcomes of surgical treatments for patients with constipation and features of colonic pseudo-obstruction.METHODS:Consecutive 42 patients who underwent surgery for chronic constipation within the last 13 years were prospectively collected.We identified a subgroup with colonic pseudo-obstruction(CPO) features,with dilatation of the colon proximal to the narrowed transitional zone,in contrast to typical slowtransit constipation(STC),without any dilated colonic segments.The outcomes of surgical treatments for chronic constipation with features of CPO were analyzed and compared with outcomes for STC.RESULTS:Of the 42 patients who underwent surgery for constipation,33 patients had CPO with dilatation of the colon proximal to the narrowed transitional zone.There were 16 males and 17 females with a mean age of 51.2 ± 16.1 years.All had symptoms of chronic intestinal obstruction,including abdominal distension,pain,nausea,or vomiting,and the mean duration of symptoms was 67 mo(range:6-252 mo).Preoperative defecation frequency was 1.5 ± 0.6 times/wk(range:1-2 times/wk).Thirty-two patients underwent total colectomy,and one patient underwent diverting transverse colostomy.There was no surgery-related mortality.Postoperative histologic examination showed hypoganglionosis or agangliosis in 23 patients and hypoganglionosis combined with visceral neuropathy or myopathy in 10 patients.In contrast,histology of STC group revealed intestinal neuronal dysplasia type B(n = 6) and visceral myopathy(n = 3).Early postoperative complications developed in six patients with CPO;wound infection(n = 3),paralytic ileus(n = 2),and intraabdominal abscess(n = 1).Defecation frequencies 3 mo after surgery improved to 4.2 ± 3.2 times/d(range:1-15 times/d).Long-term follow-up(median:39.7 mo) was available in 32 patients;all patients had improvements in constipation symptoms,but two patients needed intermittent medication for management of diarrhea.All 32 patients had distinct improvements in constipation symptoms(with a mean bowel frequency of 3.3 ± 1.3 times/d),social activities,and body mass index(20.5 kg/m 2 to 22.1 kg/m 2) and were satisfied with the results of their surgical treatment.In comparison with nine patients who underwent colectomy for STC without colon dilatation,those in the CPO group had a lower incidence of small bowel obstructions(0% vs 55.6%,P < 0.01) and less difficulty with long-distance travel(6.7% vs 66.7%,P = 0.007) on long-term follow-up.CONCLUSION:Chronic constipation patients with features of CPO caused by narrowed transitional zone in the left colon had favorable outcomes after total colectomy. | Eon Chul Han Heung-Kwon Oh Heon-Kyun Ha Eun Kyung Choe Sang Hui Moon Seung-Bum Ryoo Kyu Joo Park | 2012 | World Journal of Gastroenterology2012，18，32： | 16 |
| 3 | 东部白松半同胞家系引种苗期试验显示文摘对 38个东部白松半同胞家系进行引种苗期试验研究 ,认为家系的苗高、地径 3年生长量均差异显著 ,说明家系之间存在着真实的差异 ,优良家系的选择是有效的。应用入选的优良家系建立种子园 ,用生产的种子造林 ,可获得显著的增产效果。 | 董健 尤文忠 陆爱君 BenS.P.Wang SteveD’Eon | 2004 | 东北林业大学学报2004，32，6： | 5 |
| 4 | Complications after ileal pouch-anal anastomosis in Korean patients with ulcerative colitis显示文摘AIM:To investigate the outcomes of treatments for complications after ileal pouch-anal anastomosis(IPAA)in Korean patients with ulcerative colitis.METHODS:Between March 1998 and February 2013,72 patients(28 male and 44 female,median age 43.0years±14.0 years)underwent total proctocolectomy with IPAA.The study cohort was registered prospectively and analyzed retrospectively.Patient characteristics,medical management histories,operative findings,pathology reports and postoperative clinical courses,including early postoperative and late complications and their treatments,were reviewed from a medical record system.All of the ileal pouches were J-pouch and were performed with either the double-stapling technique(n=69)or a hand-sewn(n=3)technique.RESULTS:Thirty-one(43.1%)patients had early complications,with 12(16.7%)patients with complications related to the pouch.Pouch bleeding,pelvic abscesses and anastomosis ruptures were managed conservatively.Patients with pelvic abscesses were treated with surgical drainage.Twenty-seven(38.0%)patients had late complications during the follow-up period(82.5±50.8 mo),with 21(29.6%)patients with complications related to the pouch.Treatment for pouchitis included antibiotics or anti-inflammatory drugs.Pouch-vaginal fistulas,perianal abscesses or fistulas and anastomosis strictures were treated surgically.Pouch failure developed in two patients(2.8%).Analyses showed that an emergency operation was a significant risk factor for early pouch-related complications compared to elective procedures(55.6%vs 11.1%,P<0.05).Pouchitis was related to early(35.3%)and the other late pouch-related complications(41.2%)(P<0.05).The complications did not have an effect on pouch failure nor pouch function.CONCLUSION:The complications following IPAA can be treated successfully.Favorable long-term outcomes were achieved with a lower pouch failure rate than reported in Western patients. | Seung-Bum Ryoo Heung-Kwon Oh Eon Chul Han Heon-Kyun Ha Sang Hui Moon Eun Kyung Choe Kyu Joo Park | 2014 | World Journal of Gastroenterology2014，20，23： | 4 |
| 5 | Early estrogen-induced gene 1, a novel RANK signaling component, is essential for osteoclastogenesis显示文摘NF-κ 的受体使活跃之物; B (等级) 和 immunoreceptor 包含适配器的基于酷氨酸的激活主题(ITAM ) 是涉及调整改变的骨破折形成和骨头的必要因素。这里,我们识别早导致雌激素的基因(EEIG1 ) 1 作为一篇小说评价身体上与等级并且进一步交往的可诱导的蛋白质与 Gab2 联系的 ligand (RANKL ) , PLCγ 2 并且在 RANKL 刺激之上的 Tec/Btk kinases。EEIG1 断然调整导致 RANKL 的骨破折形成,由于它便于刺激 RANKL 的 PLCγ 的能力可能; 2 phosphorylation 和 NFATc1 正式就职。另外,设计堵住 RANK-EEIG1 相互作用的禁止的肽由减少骨破折形成禁止了导致 RANKL 的骨头破坏。一起,我们的结果作为一篇小说识别 EEIG1 评价控制调停等级的骨破折形成的发信号的部件,并且建议那指向的 EEIG1 可能为病理学的骨头再吞的处理代表新治疗学的策略。 | Han Kyoung Choi Hye Ri Kang Eutteum Jung Tae Eon Kim Jing Jing Lin Soo Young Lee | 2013 | Cell Research2013，23，4： | 4 |
| 6 | Surgical management of colonic diverticular disease:Discrepancy between right- and left-sided diseases显示文摘AIM:To compare the outcome of the surgical management of left-sided and right-sided diverticular disease.METHODS:The medical records of 77 patients who were surgically treated for diverticular disease between 1999 and 2010 in a tertiary referral hospital were retrospectively reviewed.The study population was limited to cases wherein the surgical specimen was confirmed as diverticulosis by pathology.Rightsided diverticula were classified as those arising from the cecum,ascending colon,and transverse colon,and those from the descending colon,sigmoid colon,and rectum were classified as left-sided diverticulosis.To assess the changing trend of occurrence of diverticulosis,data were compared with two previous studies of 51 patients.RESULTS:The proportion of left-sided disease cases was significantly increased compared to the results of our previous studies in 1994 and 2001,(27.5%vs48.1%,P<0.05).Moreover,no differences in gender,body mass index,multiplicity of the diverticula,fever,or leukocytosis were noted between patients with rightsided and left-sided disease.However,patients with right-sided disease were significantly younger(50.9year vs 64.0 year,P<0.01).Furthermore,left-sided disease was significantly associated with a higher incidence of complicated diverticulitis(89.2%vs 57.5%,P<0.01),combined resection due to extensive inflammation(21.6%vs 5.0%,P<0.05),operative complications(51.4%vs 27.5%,P<0.05),and in-hospital mortality(10.8%vs 0%,P<0.05),along with longer post-operative hospitalization duration(21.3±10.2 d vs 10.6±8.1 d,P<0.05).CONCLUSION:Compared with right-sided diverticular disease,the incidence of left-sided disease in Korea has increased since 2001 and is associated with worse surgical outcomes. | Heung-Kwon Oh Eon Chul Han Heon-Kyun Ha Eun Kyung Choe Sang Hui Moon Seung-Bum Ryoo Seung-Yong Jeong Kyu Joo Park | 2014 | World Journal of Gastroenterology2014，20，29： | 3 |
| 7 | Optimal follow-up duration for evaluating objective response to radiotherapy in patients with hepatocellular carcinoma:to radiotherapy in patients with hepatocellular carcinoma:a retrospective study显示文摘The time to complete or partial(objective) response to radiotherapy in patients with hepatocellular carcinoma(HCC) is variable; thus, the reported frequency of these responses depends on the length of follow-up. However, the optimum follow-up duration is unknown. We sought to determine the optimal follow-up duration by analyzing the medical records of 25 patients with 39 HCC lesions who received definitive helical tomotherapy at a daily dose of 2 to 4 Gy at 5 fractions per week, for a total dose of 40 to 60 Gy, between January 2008 and January 2013. We determined the time to objective treatment response and local recurrence after radiotherapy and assessed several predictors of delayed treatment response. The median follow-up duration was 15.2 months(range, 7.8 to 52.1 months). Among all 39 lesions, objective responses were observed for 36(92.3%). The median time to objective response was 3.9 months(range, 1.5 to 9.8 months). The objective response rates increased over time from 15.4% at 3 months to 71.8% at 6 months and 87.2% at 9 months. Age 60 years old or older and post-radiotherapy α-fetoprotein concentrations higher than pre-radiotherapy concentrations predicted delayed treatment response. The objective response rate continued to increase over 9 months. Therefore, to fully evaluate the treatment response of HCC, we recommend continuous observation for at least 9 months after radiotherapy. | Moonkyoo Kong Seong Eon Hong | 2015 | Chinese Journal of Cancer2015，34，2： | 3 |
| 8 | Influence of potassium pyrophosphate in electrolyte on coated layer of AZ91 Mg alloy formed by plasma electrolytic oxidation显示文摘The effect of potassium pyrophosphate in the electrolyte on plasma electrolytic oxidation(PEO) process for AZ91 Mg alloy was investigated.The morphologies and chemical compositions of the coating layer on the AZ91 Mg alloy were evaluated and corrosion resistance was also estimated by potentiodynamic polarization analysis.The coating layer on AZ91 Mg alloy coated from the Bath 2 containing 0.03 mol/L of potassium pyrophosphate for 360 s exhibited considerably dense structure and contained 11%-18%(mass fraction) of phosphorous.The higher content of phosphorous of coating layer coated from Bath 2 could be detected at the bottom of oxide layer,which strongly implied that the phosphorous ion might be concentrated at the barrier layer.Corrosion potential of coating layer of AZ91 Mg alloy increased and corrosion current density decreased with increasing the concentration of potassium pyrophosphate.The polarization resistance(Rp) of coating layer of AZ91 Mg alloy coated from Bath 2 was 4.65×107 Ω/cm2,which was higher than that(Rp=3.56×104 Ω/cm2) of the sample coated from electrolyte without potassium pyrophosphate.The coating layer coated from Bath 2 containing 0.03 mol/L potassium pyrophosphate exhibited the best corrosion resistance. | Jin-Young CHO Duck-Young HWANG Dong-H eon LEE Bongyoung YOO Dong-Hyuk SHIN | 2009 | 中国有色金属学会会刊:英文版2009，19，4： | 3 |
| 9 | Effects of Magnetic Annealing on Magnetic Properties in Nd_4Fe_(76)Co_3(Hf_(1-x)Ga_x)B_(16) Alloy显示文摘The best linear fit of H_c(T)/M,(T) vs 2k_1(T)/μ_0M s^2(T) infers that H_c is determined by a nucleation process in nanocrystalline two-phase magnet.The condition of the grain shapes is improved after adding Hf and Ga,but the surfaces are deteriorated by some precipitates on the boundary.Taking into account the values of α,N_(eff),the results of TEM,and Moessbauer spectroscopy,the magnetic field heat-treatment not only induces grain refinement but also causes a uniform distribution of the soft and hard phases.It is one recommendable method to improve the condition of the microstructure.Both the remanence and energy product values are increased by 20%— 30%for all ribbons after annealing with magnetic field.The magnetic interaction in Nd_2Fe_(14)B/Fe_3B + αFe based nanocrystalline two-phase magnets is studied using δM plots in this paper.It is found that the exchange coupled interaction is greatly enhanced in the sample annealed with magnetic heat-treatment,specially,Nd_4Fe_(76)Co_3Hf_(0.5)Ga_(0.5)B_(16) which achieves the highest energy product(BH)_(max)=126.4kJ/m^3. | Gao Youhui Zhu Jinghan Weng Yuqing Eon Byung Park Choong Jin Yang | 1999 | Journal of Iron and Steel Research(International)1999，6，1： | 2 |
| 10 | The effect of coupling agent on electrical and mechanical properties of carbon fiber/phenolic resin composites 显示文摘 | Choi M H J eon B H Chung I J | 2000 | Polymer2000，41，9： | 1 |
| 11 | Nosocomial outbreak of carbap- enem resistant Aeinetobacter-baumannii in Intensive Care Units and successful outbreak control program显示文摘 | Choi WS Kim SH J eon EG | 2010 | J Korean Med Sci2010，25，7： | 1 |
| 12 | Changes in the detailed pigment composition of red wine during maturity and ageing: a comprehensive study 显示文摘 | Alcalde- Eon C Escribano- Bail6n M T Santos- Buelga C | 2006 | Analytica Chimica Acta2006，563，1： | 1 |
| 13 | Development and application of a needle trap device for time-weighted average diffusive sampling显示文摘 | GONG Y EON 1 Y LOU D W | 2008 | Anal Chem2008，80，72： | 1 |
| 14 | CO2 utilization as an oxidant in the dehydrogenation of ethylbenzene to styrene over MnO2 - ZrO2 catalysts 显示文摘 | David Raju Burri Kwang Min Choi Dae -Soo Hart Jeong - Boon Koo and Sang - Eon Park | 2006 | Catalysis Today2006，115，14： | 1 |
| 15 | Room-temperature ferromagnetism in Cr-doped GaN single crystals显示文摘 | Park Sang Eon Lee Hyeon Jun Cho Yong Chan | 2002 | Applied Physics Letters2002，80，22： | 1 |
| 16 | Pharmacological charac-terization of muscarinic receptors implicated in rabbit detru-sor muscle contraction and activation of inositol phospholip-ids hydrolysis in rabbit detrusor and parotid gland显示文摘 | Barros M Coste A Eon MT | 1999 | Fun-dam Clin Pharmacol1999，13，5： | 1 |
| 17 | Functional activation of macrophages, monocytes and splenic lymphocytes by polysaccharide fraction from Tricholoma matsutake显示文摘 | Se Eun Byeon Jaehwi Lee Eunji Lee Song Yi Lee Eock Kee Hong Young Eon Kim Jae Youl Cho | 2009 | Archives of Pharmacal Research2009，，11： | 1 |
| 18 | A Quantitative Evalua- tion of Reliability of Passive Systems within Probabilistic Safety Assessment Framework for VHTR显示文摘 | Seok - Jung Han Joon - Eon Yang | 2010 | Annals of Nu- clear Energy2010，，37： | 1 |
| 19 | Differential microRNA expression signatures and cell type-specific association with Taxol resistance in ovarian cancer cells显示文摘 | Kim YW Kim EY J eon D | 2014 | Drug Des Devel Ther2014，8，： | 1 |
| 20 | Supervohage orbital radiotheropy in 36 cases of Graves' disease显示文摘 | Lioyd WC l eone Jr Cr | 1992 | Am J Ophthatmol1992，113，4： | 1 |
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