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| 1 | Hyaluronic acid fragments evoke Kupffer cells via TLR4 signaling pathway显示文摘Kupffer cells, expressing toll-like receptor 4 (TLR4), play a central role in hepatic ischemia/reperfusion (I/R) injury. Hyaluronic acid (HA) fragments, degradative products of high-molecular-weight HA (HMW-HA), acquire the ability to activate immune cells under inflammatory conditions. Here we inves- tigated whether HA fragments could activate Kupffer cells and analyzed the underlying mechanism. Kupffer cells were isolated from wild-type mice (WT, C3H/HeN) and TLR4 mutant mice (C3H/HeJ) and HA fragments were produced by the methods of enzyme digestion and chromatography. Then Kupffer cells were stimulated by HA fragments or other control stimuli. The activation of Kupffer cells was estimated as the release of pro-inflammatory cytokines. The activation of p38 MAPK pathway of Kupffer cells was checked and blocking experiments were done as well. The results indicated that HA fragments acquired the ability to activate Kupffer cells in vitro, which was TLR4 dependent and not due to contamination of lipopolysaccharide. Experiments of p38 MAPK kinase inhibition by SB-203580 verified p38 MAPK was required in HA fragments induced Kupffer cells activation. This suggests that HA fragments, degradative products of one of the major glycosaminoglycans of the extracellular matrix, play critical roles in Kupffer cell activation mediated by TLR4 signaling pathway, which is, at least partially, de- pendent on p38 MAPK activation. | ZHANG JinXiang1, WANG Hui2, XIAO Qing3, LIANG HuiFang4, LI ZhuoYa4, JIANG ChunFang1, WU HeShui5 & ZHENG QiChang5 1 Department of Emergency Surgery, Union Hospital Affiliated to Huazhong University of Science and Technology, Wuhan 430022, China 2 Department of Medical Genetics, Tongji Medical College Affiliated to Huazhong University of Science and Technology, Wuhan 430030, China 3 Department of Ophthalmology, Union Hospital Affiliated to Huazhong University of Science and Technology, Wuhan 430022, China 4 Department of Medical Immunology, Tongji Medical College Affiliated to Huazhong University of Science and Technology, Wuhan 430030, China 5 Department of General Surgery, Union Hospital Affiliated to Huazhong University of Science and Technology, Wuhan 430022, China | 2009 | Science China(Life Sciences)2009，52，2： | 33 |
| 2 | TLR4 signaling induced TLR2 expression in the process of mimic cerebral ischemia/reperfusion in vitro显示文摘Both TLR4 and TLR2 participated in the mediation of the inflammatory injury in the process of partial cerebral ischemia/reperfusion.However,it still remains unclear whether a crosstalk exists between TLR2 and TLR4 in ischemic cerebral damage.In the present study,we investigated the effect of TLR4 signaling on TLR2 expression during mimic cerebral I/R in vitro.BV-2 cells were cultured and treated with ischemia/reperfusion,then transfected with the plasmid pEGFP-H1/TLR4-siRNA,the plasmid pEGFP-H1/control sequence-siRNA and the blank plasmid,respectively.Interestingly,the expression of TLR2 and TLR4 mRNA and protein,NF-κB p65 mRNA and supernatant TNF-α level were significantly higher in ischemia/reperfusion treated cells than those lack of ischemia/reperfusion treatment,and as compared with those in ischemia/reperfusion treated cells without transfection,no significant differences about the above mentioned gene and protein expression were found in the blank plasmid tranfected cells and the plasmid pEGFP-H1/control sequence-siRNA transfected cells respectively,while the expression levels in the plasmid pEGFP-H1/TLR4-siRNA transfected cells were significantly lower.Additionally,in order to determine the effects of pyrrolidinediethyldithiocarbamate (PDTC),an NF-κB inhibitor,on the TLR4-induced TLR2 expression in BV-2 cells treated with ischemia/reperfusion,it was found that TLR4 and TLR2 mRNA expressions in PDTC pretreated cells were significantly lower in comparison with normal saline pretreated cells and non-pretreated cells.The data suggested that TLR2 activation,signaled by TLR4 and regulated by NF-κB,might be directly involved play an important role in ischemia/reperfusion induced brain damage. | SUN Peng1,ZHANG Qing2,HAN JiYuan1,TIAN Yuan3 & ZHANG JingHui3 1Department of Emergency,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430022,China 2Department of Anesthesia,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430022,China 3Department of General Surgery,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430022,China | 2010 | Science China(Life Sciences)2010，53，2： | 30 |
| 3 | Effect of L-NAME on nitric oxide and gastrointestinal motility alterations in cirrhotic rats显示文摘AIM: To invsstigare the effect of L-NAME on nitric oxide andgastriubtestubal motility alterations in cirrhotic ratsMETHODS: Rats with cirrhosis induced by carbontetrachloride were randomly divided into two groups, one( n= 13) receiving 0. 5 mg@ kg-1 per clay of NG-nitro-L-argininemethyl ester (L-NAME), a nitric oxide synthase inhibitor,for 10 days, whereas the other group ( n = 13) and control( n = 10) rats were administrated the same volume of 9 g@ L-1saline.Half gastric emptying time and 2 h residual rate weremeasured by SPECT, using 99m Tc-DTPA-labeled bariumsuifate as test meal. Gastrointestinal transition time wasrecorded simultaneously. Serum concentration of nitrcoxide (NO) was determined by the kinetic cadmiunreduction and colorimetric methods. ImmunohistochemicalSABC method was used to observe the expression anddistribution of three types of nitric oxide synthase (NOS)isoforms in the mt gastrointestinal tract. Western blot wasused to detect expression of gastrointestinal NOS isoforms.RESULTS: Half gastric emptying time and trans-gastrointestinal time were significantly prolonged( 124.0 ± 26.4min; 33.7± 8.9min;72.1 ± 15.3 min; P<0.01), (12.4±0.5h; 9.5±0.3 h; 8.2±0.8 h; P<0.01), 2h residual rate wasraised in cirrhotic rots than in controls and cirrhotic ratstreated with L-NAME(54.9± 7.6 % ,13.7 ± 3.2 %, 34.9± 10.3%, P< 0.01). Serum concentration of NO was significantlyincreased in cirrhotic rots than in the other groups (8.20 ± 2.48)μmol@L-1, (5.94± 1.07) μmol@L-1 ,and control (5.66± 1.60) tμmol@L-1, P< 0.01. NOS staining intensities which weremainly located in the gastrointestinal tissues were markedlylower in cirrhotic rats than in the controls and cirrhotic ratsafter treated with L- NAME.CONCLUSION: Gastrointestinal motility was remarkablyinhibited in cirrhotic rats, which could he alleviated by L-NAME. Nitric oxide may play an important role in theinhibition of gastrointestinal motility in cirrhotic rats. | Xin Wang Zong-You Zhang Mei Lan Ji-Yan Miao Xue-Gang Guo Yong-Quan Shi Yan-Qiu Zhao Jie Ding Kai-Cun Wu Dai-Ming Fan,Institute of Digestive disease,Xijing Hospital,Fourth Military Medical University,Xi’an 710032,Shaanxi Province,China Yue-Xia Zhong,Emergency Department,Tangdu Hospital,Fourth Military Medical University,Xi’an 710038,Shaanxi Province,China Ju Lu,Class EE 87,Department of Electronic Engineering,Tsinghua University,Beijing 100084,China Bo-Rong Pan,Oncology Center,Xijing Hospital,Fourth Military Medical University,Xi’an 710032,Shaanxi Province,China | 2002 | World Journal of Gastroenterology2002，8，2： | 19 |
| 4 | Management of traumatic hemothorax by closed thoracic drainage using a central venous catheter显示文摘Objective:To evaluate the efficacy and safety of the treatment of traumatic hemothorax by closed pleural drainage using a central venous catheter(CVC),compared with using a conventional chest tube.Methods:A prospective controlled study with the Ethics Committee approval was undertaken.A total of 407 patients with traumatic hemothorax were involved and they were randomly assigned to undergo closed pleural drainage with CVCs(n=214) or conventional chest tubes(n=193).The Seldinger technique was used for drainage by CVC,and the conventional technique for drainage by chest tube.If the residual volume of the hemothorax was less than 200 ml after the daily volume of drainage decreased to below 100 ml for two consecutive days,the treatment was considered successful.The correlative data of efficacy and safety between the two groups were analyzed using t or chi-squared tests with SPSS 13.0.A P value of less than 0.05 was taken as indicating statistical significance.Results:Compared with the chest tube group,the operation time,fraction of analgesic treatment,time of surgical wound healing,and infection rate of surgical wounds were significantly decreased(P<0.05) in the CVC group.There were no significant differences between the two groups in the success rate of treatment and the incidence of serious complications(P>0.05),or in the mean catheter/tube indwelling time and mean medical costs of patients treated successfully(P>0.05).Conclusions:Management of medium or large traumatic hemothoraxes by closed thoracic drainage using CVC is minimally invasive and as effective as using a conventional large-bore chest tube.Its complications can be prevented and it has the potential to replace the large-bore chest tube. | Jian-hua YI1,Hua-bo LIU2,Mao ZHANG1,Jun-song WU1,Jian-xin YANG1,Jin-ming CHEN1,Shan-xiang XU1,Jian-an WANG1(1Department of Emergency,the Second Affiliated Hospital,School of Medicine,Zhejiang University,Hangzhou 310009,China)(2Department of Emergency,Zhoushan Hospital of Zhejiang Province,Zhoushan 316004,China) | 2012 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2012，13，1： | 18 |
| 5 | Quick image-processing method of UAV without control points data in earthquake disaster area显示文摘The methods of unmanned aerial vehicles images splicing rapidly and rectifying without control points data, only using auxiliary data recorded by unmanned aerial vehicle (UAV) system, were researched. Two algorithms were proposed, including UAV images auto- splicing rapidly after image blocking and UAV images rectifying based on pseudo center points of auxiliary data. When SIFT algorithm for UAV images splicing is applied, the accuracy is very high, but the efficiency is very low. The splicing efficiency is improved greatly based on SIFT algorithm after image blocking. The results show that rectifying accuracy is very high and has no visual dislocation when pseudo center points of auxiliary data is applied. | LI Chang-chun1, ZHANG Guang-sheng1, LEI Tian-jie2, 3, GONG A-du2, 3 1. School of Surveying & Land Information Engineering, Henan Polytechnic University, Jiaozuo 454000, China 2. Key Laboratory of Environmental Change and Natural Disaster, Ministry of Education, Beijing Normal University, Beijing 100875, China 3. Ministry of Civil Affairs/Ministry of Education of China Academy of Disaster Reduction and Emergency Management, Beijing Normal University, Beijing 100875, China | 2011 | 中国有色金属学会会刊:英文版2011，21，S3： | 13 |
| 6 | Suppression of Type 1 Insulin-like Growth Factor Receptor Expression by Small Interfering RNA Inhibits A549 Human Lung Cancer Cell Invasion in vitro and Metastasis in Xenograft Nude Mice显示文摘癌症侵略和转移,包含许多病理学的过程和 cytophysiological 变化,贡献肺癌症的高死亡。类型 1insulin-like 生长因素受体(IGF-1R ) ,把前进和侵略与癌症联系了,是在肺癌症的一个潜在的反侵略和反转移目标。禁止肺癌症房间的侵略性质,我们在由小介入 RNA ( siRNA )技术的 A549 人的肺癌症房间的成功地下面调整的 IGF-1R 基因表达,并且评估了它的效果oninvasion相关的基因表达,在 vitro 侵略的肿瘤房间,并且在有为 IGF-1R 表示发卡 siRNA 的一个原生质标志的异种皮移植 nudemice.A549 房间 transfected 的转移在 mRNA 水平以及蛋白质 level.Inbiological 试金显示出一个显著地减少的 IGF-1R 表达式, transfected A549 房间显示出 cell-matrixadhesion ,移植和侵略的重要减小。与这些结果一致,我们发现那条下面规定大减小附随地在侵略相关的基因表达伴随的 ofIGR-1R , includingMMP-2 , MMP-9 , u-PA ,并且为 IGF-1R 的 plasmidexpressing 发卡 siRNA 的 IGF-1R 特定的下游的 p-Akt.Direct 尾巴静脉注射显著地在结果显示出的 nudemice.Our 禁止了肺转移的形成是的 siRNA 的治疗学的潜力为在禁止肺癌症侵略和转移的基因治疗的一个方法。 | Jianfang QIAN~1 Aiqiang DONG~1 Minjian KONG~1 Zhiyuan MA~2 Junqiang FAN~1 and Guanyu JIANG~3 ~1Department of Cardiothoracic Surgery,Second Affiliated Hospital,School of Medicine,Zhejiang University,Hangzhou 310009,China ~2Department of Cardiovascular Surgery,Shanghai Jiaotong University Affiliated First People’s Hospital,Shanghai 200080,China ~3Department of Emergency,Second Affiliated Hospital School of Medicine,Zhejiang University,Hangzhou 310009,China | 2007 | Acta Biochimica et Biophysica Sinica2007，39，2： | 9 |
| 7 | Spatial prediction and analysis of Himalayan marmot plague natural epidemic foci in China based on HJ-1 satellite data显示文摘Plague,caused by the gram-negative bacterium Yersinia pestis,is a serious and rapidly progressing illness in humans that can be fatal if not treated effectively.The Qinghai-Tibet Plateau is the largest area of natural Himalayan marmot(Marmota himalayana) plague foci in China and covers more than 630000 km2.Akesai County in Gansu Province is a part of this natural focus of plague and was chosen as a study area.Our study used an ecological niche modeling(ENM) approach to predict the potential distribution of the Himalayan marmot.Environment and Disaster Monitor Satellite(HJ-1) data was used to investigate environment factors that affect plague host animal activity.Host animal point data from active surveillance was combined with environmental variables from the HJ-1 satellite and other databases,and the models of the potential distribution of Himalayan marmot were produced with the Genetic Algorithm for Rule-Set Production(GARP).The probability of marmot presence was divided into 0-5%,5%-20%,20%-40%,40%-80%,and 80%-100% subgroups.Areas with 80%-100% probability exhibited the greatest potential for the presence of Himalayan marmot.According to the predicted potential distribution of Himalayan marmot in the study area,active surveillance of plague hosts and plague control and prevention could be more efficient. | GAO MengXu1,4,LI XiaoWen1,2,CAO ChunXiang1,ZHANG Hao1,LI Qun3,ZHOU Hang3 HE QiSheng1,4,XU Min1,4,ZHAO Jian1,4,ZHENG Sheng1,4 & CHEN Wei1,4 1State Key Laboratory of Remote Sensing Science,Jointly Sponsored by the Institute of Remote Sensing Applications of Chinese Academy of Sciences and Beijing Normal University,Beijing 100101,China 2School of Geography,Beijing Normal University,Beijing 100875,China 3Office for Disease Control and Emergency Response,Chinese Center for Disease Control and Prevention,Beijing 102206,China 4Graduate University of Chinese Academy of Sciences,Beijing 100049,China | 2010 | Science China Earth Sciences2010，53，S1： | 5 |
| 8 | Gastroesophageal reflux disease management according to contemporary international guidelines:A translational study显示文摘AIM:To test the Genval recommendations and the usefulness of a short trial of proton pump inhibitor(PPI) in the initial management and maintenance treatment of gastroesophageal reflux disease(GERD)patients. METHODS:Five hundred and seventy seven patients with heartburn were recruited.After completing a psychometric tool to assess quality of life(PGWBI)and a previously validated GERD symptom questionnaire (QUID),patients were grouped into those with esophagitis(EE,n=306)or without mucosal damage (NERD,n=271)according to endoscopy results. The study started with a 2-wk period of high dose omeprazole(omeprazole test);patients responding to this PPI test entered an acute phase(3 mo)of treatment with any PPI at the standard dose.Finally,those patients with a favorable response to the standard PPI dose were maintained on a half PPI dose for a further 3-mo period. RESULTS:The test was positive in 519(89.9%)patients,with a greater response in EE patients(96.4%) compared with NERD patients(82.6%)(P=0.011). Both the percentage of completely asymptomatic patients,at 3 and 6 mo,and the reduction in heartburn intensity were significantly higher in the EE compared with NERD patients(P<0.01).Finally,the mean PGWBI score was significantly decreased before and increased after therapy in both subgroups when compared with the mean value in a reference Italian population. CONCLUSION:Our study confirms the validity of the Genval guidelines in the management of GERD patients. In addition,we observed that the overall response to PPI therapy is lower in NERD compared to EE patients. | Fabio Pace Gabriele Riegler Annalisa de Leone Patrizia Dominici Enzo Grossi the EMERGE Study Group | 2011 | World Journal of Gastroenterology2011，17，9： | 5 |
| 9 | Spatial patterns of ecosystem carbon residence time in Chinese forests显示文摘Capacity of carbon sequestration in forest ecosystem largely depends on the trend of net primary production (NPP) and the length of ecosystem carbon residence time. Retrieving spatial patterns of ecosystem carbon residence time is important and necessary for accurately predicting regional carbon cycles in the future. In this study, a data-model fusion method that combined a process-based regional carbon model (TECO-R) with various ground-based ecosystem observations (NPP, biomass, and soil organic carbon) and auxiliary data sets (NDVI, meteorological data, and maps of vegetation and soil texture) was applied to estimate spatial patterns of ecosystem carbon residence time in Chinese forests at steady state. In the data-model fusion, the genetic algorithm was used to estimate the optimal model parameters related with the ecosystem carbon residence time by minimizing total deviation between modeled and observed values. The results indicated that data-model fusion technology could effectively retrieve model parameters and simulate carbon cycling processes for Chinese forest ecosystems. The estimated carbon residence times were highly heterogenous over China, with most of regions having values between 24 and 70 years. The deciduous needleleaf forest and the evergreen needleleaf forest had the highest averaged carbon residence times (73.8 and 71.3 years, respectively), the mixed forest and the deciduous broadleaf forest had moderate values (38.1 and 37.3 years, respectively), and the evergreen broadleaf forest had the lowest value (31.7 years). The averaged carbon residence time of forest ecosystems in China was 57.8 years. | ZHOU Tao1,2, SHI PeiJun1,2, JIA GenSuo3, LI XiuJuan1,2 & LUO YiQi4 1 State Key Laboratory of Earth Surface Processes and Resource Ecology, Beijing Normal University, Beijing 100875, China 2 Academy of Disaster Reduction and Emergency Management, Ministry of Civil Affairs & Ministry of Education, Beijing 100875, China 3 Key Laboratory of Regional Climate-Environment Research for Temperate East Asia, Chinese Academy of Sciences, Beijing 100029, China 4 Department of Botany and Microbiology, University of Oklahoma, Norman, OK 73019, USA | 2010 | Science China Earth Sciences2010，53，8： | 5 |
| 10 | Information content security on the Internet:the control model and its evaluation显示文摘Flooding of harmful information on the Internet seriously endangers the physiological and mental health of teenagers. Due to the user-friendliness of the Internet as well as the difficulty in the authentication for the access of specific categories of information, curbing the transmission of harmful information, i.e., assuring the information content security (ICS), has become a reasonable yet challenging alternative. At present, there is an urgent need to develop a systematic model that can effectively carry out the curbing. In fact, curbing the transmission of harmful information by way of filtering can be modeled by access control. In the paper, based on the three core-elements of communication, namely, 'Who communicates with whom', 'How do they communicate' and 'What is the content of communication', we propose a control model, called ICCON. Unlike the existing access control, the reference monitor (RM) of our model is placed in the transmission channel, and moreover, an evaluation frame is proposed, through which the effectiveness of the RM in controlling information transmission on the Internet can be quantitatively evaluated. | FANG BinXing1, GUO YunChuan2,3 & ZHOU Yuan4 1School of Computer, Beijing University of Posts and Telecommunications, Beijing 100029, China 2Institute of Computing Technology, Chinese Academy of Sciences, Beijing 100190, China 3Graduate University of Chinese Academy of Sciences, Beijing 100049, China 4National Computer Network Emergency Response Technical Team/Coordination Center of China, Beijing 100029, China | 2010 | Science China(Information Sciences)2010，53，1： | 4 |
| 11 | Spatial patterns in temperature sensitivity of soil respiration in China: Estimation with inverse modeling显示文摘Temperature sensitivity of soil respiration (Q10) is an important parameter in modeling the effects of global warming on ecosystem carbon release. Experimental studies of soil respiration have ubiquitously indicated that Q10 has high spatial heterogeneity. However, most biogeochemical models still use a constant Q10 in projecting future climate change and no spatial pattern of Q10 values at large scales has been derived. In this study, we conducted an inverse modeling analysis to retrieve the spatial pattern of Q10 in China at 8 km spatial resolution by assimilating data of soil organic carbon into a proc-ess-based terrestrial carbon model (CASA model). The results indicate that the optimized Q10 values are spatially heterogeneous and consistent to the values derived from soil respiration observations. The mean Q10 values of different soil types range from 1.09 to 2.38, with the highest value in volcanic soil, and the lowest value in cold brown calcic soil. The spatial pattern of Q10 is related to environmental factors, especially precipitation and top soil organic carbon content. This study demonstrates that inverse modeling is a useful tool in deriving the spatial pattern of Q10 at large scales, with which being incorporated into biogeochemical models, uncertainty in the projection of future carbon dynamics could be potentially reduced. | ZHOU Tao1,2, SHI PeiJun1,2, HUI DaFeng3 & LUO YiQi4 1 State Key Laboratory of Earth Surface Processes and Resource Ecology, Beijing Normal University, Beijing 100875, China 2 Academy of Disaster Reduction and Emergency Management, Ministry of Civil Affairs & Ministry of Education, Beijing 100875, China 3 Department of Biological Sciences, Tennessee State University, Nashville, TN 37209, USA 4 Department of Botany and Microbiology, University of Oklahoma, Norman, OK 73019, USA | 2009 | Science China(Life Sciences)2009，52，10： | 4 |
| 12 | Short-segment Barrett's esophagus and cardia intestinal metaplasia:A comparative analysis显示文摘AIM:To investigate the endoscopy and histology of short-segment Barrett's esophagus (SSBE) and cardia intestinal metaplasia (CIM),and their correlation with Helicobacter pylori (H. pylori) gastritis and gastroesophageal reflux disease (GERD). METHODS:Biopsy specimens were taken from 32 SSBE patients and 41 CIM patients with normal appearance of the esophagogastric junction. Eight biopsy specimens from the lower esophagus,cardia,and gastric antrum were stained with hematoxylin/eosin,Alcian blue/periodic acid-Schiff,Alcian blue/high iron diamine and Gimenez dye. Results were graded independently by one pathologist. RESULTS:The SSBE patients were younger than the CIM patients (P < 0.01). The incidence of dysplasia and incomplete intestinal metaplasia subtype was higher in SSBE patients than in CIM patients (P < 0.01). H. pylori infection was correlated with antral intestinal metaplasia (P < 0.05),but not with reflux symptomatic,endoscopic,or histological markers of GERD in CIM patients. SSBE was correlated with reflux symptomatic and endoscopic esophagitis (P < 0.01),but not with H. pylori infection and antral intestinal metaplasia. CONCLUSION:Dysplasia risk is significantly greater in SSBE patients than in CIM patients. CIM is a manifestation of H. pylori-associated and multifocal atrophic gastritis,whereas SSBE may result from GERD. | Ying Chang,Digestive Endoscopic Center,Shanghai Sixth Hospital,Shanghai Jiao Tong University,Shanghai 200233,China Bin Liu,Department of Emergence Surgery,Shaanxi Provincial People’s Hospital,Xi’an 710068,Shaanxi Province,China Gui-Sheng Liu,Department of Gastroenterology,Shaanxi Provincial People’s Hospital,Xi’an 710068,Shaanxi Province,China Tao Wang,Department of Gastroenterology,First Hospital of Xi’ an Jiaotong University,Xi’an 710061,Shaanxi Province,China Jun Gong,Department of Gastroenterology,Second Hospital of Xi’an Jiaotong University,Xi’an 710004,Shaanxi Province,China | 2010 | World Journal of Gastroenterology2010，16，48： | 3 |
| 13 | Key technology of mine underground mobile positioning based on LiDAR and coded sequence pattern显示文摘Technologies of underground mobile positioning were proposed based on LiDAR data and coded sequence pattern landmarks for mine shafts and tunnels environment to meet the needs of fast and accurate positioning and navigation of equipments in the mine underground without satellite navigation signals. A coded sequence pattern was employed for automatic matching of 3D scans. The methods of SIFT feature, Otsu segmentation and fast hough transformation were described for the identification, positioning and interpretation of the coded sequence patterns, respectively. The POSIT model was presented for speeding up computation of the translation and rotation parameters of LiDAR point data, so as to achieve automatic 3D mapping of mine shafts and tunnels. The moving positioning experiment was applied to evaluating the accuracy of proposed pose estimation method from LiDAR scans and coded sequence pattern landmarks acquired in an indoor environment. The performance was evaluated using ground truth data of the indoor setting so as to measure derivations with six degrees of freedom. | WANG Zhi1, 2, WU Li-xin1, 2, LI Hui-ying3 1. College of Resources and Civil Engineering, Northeastern University, Shenyang 110004, China 2. Academy of Disaster Reduction and Emergency Management, Ministry of Civil Affairs and Ministry of Education, Beijing Normal University, Beijing 100875, China 3. College of Computer Science and Technology, Jilin University, Changchun 130012, China | 2011 | 中国有色金属学会会刊:英文版2011，21，S3： | 3 |
| 14 | Hepatic veno-occlusive disease induced by Gymura segetum: report of two cases显示文摘BACKGROUND: Hepatic veno-occlusive disease (VOD) or sinusoidal obstruction syndrome is associated with a high mortality because of its severity. Gymura segetum, a Chinese herbal medicine, is always used to cure injury and bleeding in rural areas in China. This study was undertaken to better understand VOD and its relations to the effect of Gymura segetum. METHODS: Between 2000 and 2002,two patients were admitted to our department because of VOD. Before admission, both of them had been injured and taken oral decoction of patent drug Gymura segetum. We analyzed the clinical manifestations, diagnosis and therapy of the two patients. RESULTS: Pyrrolizidine in Panax notginseng was proved to induce VOD. The diagnosis of VOD depended on hepatic biopsy. CONCLUSION: Gymura segetum can induce VOD. More attention should be paid to its unsuscepted side effects. | Hui-Fen Dai, Yuan Gao, Ming Yang, Chao-Hui Yu, Zhu-Ying Gu and Wei-Xing Chen Zhejiang University School of Medicine, Hangzhou 310031, China Department of Emergency Medicine and Department of Gastroenterology , First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China | 2006 | Hepatobiliary & Pancreatic Diseases International2006，5，3： | 3 |
| 15 | Management of regional citrate anticoagulation for continuous renal replacement therapy:guideline recommendations from Chinese emergency medical doctor consensus显示文摘Continuous renal replacement therapy(CRRT)is widely used for treating critically-ill patients in the emergency department in China.Anticoagulant therapy is needed to prevent clotting in the extracorporeal circulation during CRRT.Regional citrate anticoagulation(RCA)has been shown to potentially be safer and more effective,and is now recommended as the preferred anticoagulant method for CRRT.However,there is still a lack of unified standards for RCA management in the world,and there are many problems in using this method in clinical practice.The Emergency Medical Doctor Branch of the Chinese Medical Doctor Association(CMDA)organized a panel of domestic emergency medicine experts and international experts of CRRT to discuss RCA-related issues,including the advantages and disadvantages of RCA in CRRT anticoagulation,the principle of RCA,parameter settings for RCA,monitoring of RCA(mainly metabolic acid-base disorders),and special issues during RCA.Based on the latest available research evidence as well as the paneled experts'clinical experience,considering the generalizability,suitability,and potential resource utilization,while also balancing clinical advantages and disadvantages,a total of 16 guideline recommendations were formed from the experts'consensus. | Shu-Yuan Liu Sheng-Yong Xu Lu Yin Ting Yang Kui Jin Qiu-Bin Zhang Feng Sun Ding-Yu Tan Tian-Yu Xin Yu-Guo Chen Xiao-Dong Zhao Xue-Zhong Yu Jun Xu Emergency Medical Doctor Branch of the Chinese Medical Doctor Association | 2023 | Military Medical Research2023，10，6： | 3 |
| 16 | Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: a collaborative meta-analysis of 102 prospective studies显示文摘 | The Emerging Risk Factors Collaboration | 2010 | The Lancet2010，，9733： | 3 |
| 17 | Security Situation in Afghanistan显示文摘In the first half of 2006, the Taliban armed forces intensified their terrorist attacks in Afghanistan, thus drawing attention of the international community. The worse situation there will inevitably produce negative impacts on the security in the west regions of China. Based on a thorough analysis of the situation, the author concluded that the low-intensity conflicts there would continue in some time to come. | Dr. Fang Jinying is an Associate Professor of the Institutes of Security and Strategic Studies, China Institutes of Contemporary International Relations (CICIR). Her major academic interests are in the worldwide Islamic extremism and South Asian security. She has written a number of articles. She is also the author of The Emergency and Development of “Ethnic Chinese Issue” in Southeast Asia (2001), and coauthor of Focus on Global Ethnic Issues (2001) and Focus on World Religious Issues (2003). | 2006 | Contemporary International Relations2006，16，6： | 2 |
| 18 | Part II: pediatric advanced life support显示文摘 | Standards and guidelines for cardiopulmonary resuscitation (CPR) and emergency cardiac care (ECC) | 1986 | JAMA1986，255，21： | 1 |
| 19 | Current status and future outlook for bonded permanent magnet显示文摘 | V Archambault D Pere Emerge | 1999 | Mat Res Soc Symp Proc1999，1，： | 1 |
| 20 | Trial of abciximab and without low-dose reteplase for acute myocardial infarction显示文摘 | Strategies for Patency Enhancement in the Emergency Department Group | 2000 | Circulation2000，101，： | 1 |
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