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| 1 | Diagnostic non-invasive model of large risky esophageal varices in cirrhotic hepatitis C virus patients显示文摘AIM To build a diagnostic non-invasive model for screening of large varices in cirrhotic hepatitis C virus(HCV) patients. METHODS This study was conducted on 124 post-HCV cirrhotic patients presenting to the clinics of the Endemic Medicine Department at Mansoura University Hospital for evaluation before HCV antiviral therapy: 78 were Child A and 46 were Child B(score ≤ 8). Inclusion criteria for patients enrolled in this study was presence of cirrhotic HCV(diagnosed by either biopsy or fulfillment of clinical basis). Exclusion criteria consisted of patients with other etiologies of liver cirrhosis, e.g., hepatitis B virus and patients with high MELD score on transplant list. All patients were subjected to full medical record, full basic investigations, endoscopy, and computed tomography(CT), and then divided into groups with no varices, small varices, or large risky varices. In addition, values of Fibrosis-4 score(FIB-4), aminotransferase-to-platelet ratio index(APRI), and platelet count/splenic diameter ratio(PC/SD) were also calculated.RESULTS Detection of large varies is a multi-factorial process, affected by many variables. Choosing binary logistic regression, dependent factors were either large or small varices while independent factors included CT variables such coronary vein diameter, portal vein(PV) diameter, lieno-renal shunt and other laboratory noninvasive variables namely FIB-4, APRI, and platelet count/splenic diameter. Receiver operating characteristic(ROC) curve was plotted to determine the accuracy of non-invasive parameters for predicting the presence of large esophageal varices and the area under the ROC curve for each one of these parameters was obtained. A model was established and the best model for prediction of large risky esophageal varices used both PC/SD and PV diameter(75% accuracy), while the logistic model equation was shown to be(PV diameter ×-0.256) plus(PC/SD ×-0.006) plus(8.155). Values nearing 2 or more denote large varices.CONCLUSION This model equation has 86.9% sensitivity and 57.1% specificity, and would be of clinical applicability with 75% accuracy. | Hatem Elalfy Walid Elsherbiny Ashraf Abdel Rahman Dina Elhammady Shaker Wagih Shaltout Ayman Z Elsamanoudy Bassem El Deek | 2016 | World Journal of Hepatology2016，8，24： | 5 |
| 2 | Relation betweensingle serum progesterone assay and viability of the first trimester pregnancy显示文摘 | Abdelazim IA Elezz AA Elsherbiny M | 2012 | Springerplus2012，1，1： | 1 |
| 3 | Holographic antennas:concept,analysis,andparameters显示文摘 | ElSherbiny M Fathy A E Rosen A | 2004 | IEEE Transactions AntennasPropagation2004，52，3： | 1 |
| 4 | PV and thermally driven small-scale, stand-alone solar desalination systems with very low maintenance needs显示文摘 | Fath H E S Elsherbiny S M Hassan A A | 2008 | Desalination2008，225，13： | 1 |
| 5 | A Novel Low-pass Filter With Ultra-wide Stop-band and Improved Q-factor Performance Using H-Defected Ground Structure (DGS) 显示文摘 | Boutejdar Amari A Elsherbini S | 2007 | IEEE Antennas and Propagation International Symposium2007，，6： | 1 |
| 6 | Relation be- tween single serum progesterone assay and viability of the first trimester pregnancy显示文摘 | Abdelazim IA Elezz AA Elsherbiny M | 2012 | Springerplus2012，1，1： | 1 |
| 7 | Experimental investigation of thermal contact resistance in plain-fin-and-tube evaporators with collarless fins显示文摘 | ElSherbini A I Hrnjak P S | 2003 | International Journal of Refrigeration2003，26，5： | 1 |
| 8 | Characterization and Catalytic Activity of New Metal-organic Frameworks Resulted from Self-assembly of Ph3SnCI, K[Cu(CN)2] and Nitrogen Donor Ligands显示文摘 | Etaiw, Safaa El-din H. Elsherbiny, Abeer S. Badr El-din, Ahmed S. | 2011 | Chinese Journal of Chemistry2011，29，7： | 1 |
| 9 | Adenosine receptors: new thera- peutic targets for inflammation in diabetic nephropathy 显示文摘 | Elsherbiny NM A1-Gayyar MM | 2013 | In- flamm Allergy Drug Targets2013，12，： | 1 |
| 10 | Sesamin attenuates neurotoxicity in mouse model of ischemic brain stroke 显示文摘 | Ahmad S Elsherbiny N M Haque R | 2014 | Neurotoxicology2014，45，： | 1 |
| 11 | A novel lowpass filter with ultra-wide stopband and improved q-factor performance using H-defected ground structure (DGS) 显示文摘 | Boutejdar Amari A Elsherbini S | 2007 | IEEE Antenna Propagation Int Symp2007，6，： | 1 |
| 12 | Synthesis and antimicrobial activity of some 4-amino-5aryl-1,2,4-triazole-3-thiones and their derivatives 显示文摘 | EWEISS N F BAHAJAJ A A ELSHERBINI E A | 1986 | Synthesis of Heterocycles1986，23，： | 1 |
| 13 | PV and thermally driven small-scale, stand-alone solar desalina- tion systems with very low maintenance needs显示文摘 | Fath H E S Elsherbiny S M Hassan A A | 2008 | De- salinatior2008，225，： | 1 |
| 14 | Interaction of brainfatty acid-binding protein with the polyunsaturated fattyacid environment as a potential determinant of poor prog-nosis in malignant glioma 显示文摘 | Elsherbiny ME’Emara M Godbout R | 2013 | Prog Lipid Res2013，52，4： | 1 |
| 15 | Interaction of brain fatty acid-binding protein with the polyunsaturated fatty acid environment as a potential determinant of poor prognosis in malignant glioma显示文摘 | Elsherbiny ME Emara M Godbout R | 2013 | Prog Lipid Res2013，52，4： | 1 |
| 16 | Surface voltages and resistance of grounding systems of geid and rods in two-layer earth by the rapid Galerkin's moment method显示文摘 | Elsherbiny M M Salams M M A | 1997 | IEEE Transactions on Power Delivery1997，12，1： | 1 |
| 17 | A fast and accurate analysis of grounding resistance of a driven rodbod in a two-layer soil显示文摘 | Chow Y L Salama M M A | 1996 | IEEE Transaction on Power Delivery1996，11，2： | 1 |
| 18 | Mean platelet volume and its relation to insulin resistance in non-diabetic patients with slow coronary flow显示文摘 | Elsherbiny I A Shoukry A El Tahlawi M A | 2012 | J Cardiol2012，59，2： | 1 |
| 19 | Mean platelet volume and its relation to insulin resistance in non-diabetic patients with slow coronary flow显示文摘 | Elsherbiny IA Shoukry A El Tahlawi MA | | 0，，： | 1 |
| 20 | Contribution of TNF-o: to the development of retinal neurodegenerative disorders 显示文摘 | A1-Gayyar MM Elsherbiny NM | 2013 | Eur Cytokine Netw2013，24，： | 1 |
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