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| 1 | Is regular physical activity a key to mental health? Commentary on 'Association between physical exercise and mental health in 1.2 million individuals in the USA between 2011 and 2015:A cross-sectional study',by Chekroud et al.,published in Lancet Psychiat显示文摘The recent publication by Chekroud et al . in Lancet Psychiatry focuses on the relationship between physical exercise and mental health.Mental health is defined as optimal personal functioning 'resulting in productive activities,fulfilling relationships with other people,and the ability to adapt to change and to cope with adversity'.(p.4) Recently,mental health has no longer been described as a dichotomous state but as a continuum,with personal mental states ranging from highly functional to mentally ill. | Anne-Marie Elbe Stine NylANDsted Lyhne Esben Elholm Madsen Peter Krustrup | 2019 | Journal of Sport and Health Science2019，8，1： | 6 |
| 2 | Cytoprotective effects of amifostine,ascorbic acid and N-acetylcysteine against methotrexate-induced hepatotoxicity in rats显示文摘AIM:To investigate the potential role of oxidative stress and the possible therapeutic effects of N-acetyl cysteine(NAC),amifostine(AMF)and ascorbic acid(ASC)in methotrexate(MTX)-induced hepatotoxicity.METHODS:An MTX-induced hepatotoxicity model was established in 44 male Sprague Dawley rats by administration of a single intraperitoneal injection of20 mg/kg MTX.Eleven of the rats were left untreated(Model group;n=11),and the remaining rats were treated with a 7-d course of 50 mg/kg per day NAC (MTX+NAC group;n=11),50 mg/kg per single dose AMF(MTX+AMF group;n=11),or 10 mg/kg per day ASC(MTX+ASC group;n=11).Eleven rats that received no MTX and no treatments served as the negative control group.Structural and functional changes related to MTX-and the various treatments were assessed by histopathological analysis of liver tissues and biochemical assays of malondialdehyde(MDA),superoxide dismutase(SOD),catalase,glutathione(GSH)and xanthine oxidase activities and of serum levels of aspartate aminotransferase,alanine aminotransferase,alkaline phosphatase and total bilirubin.RESULTS:Exposure to MTX caused structural and functional hepatotoxicity,as evidenced by significantly worse histopathological scores[median(range)injury score:control group:1(0-3)vs 7(6-9),P=0.001]and significantly higher MDA activity[409(352-466)nmol/g vs 455.5(419-516)nmol/g,P<0.05].The extent of MTX-induced perturbation of both parameters was reduced by all three cytoprotective agents,but only the reduction in hepatotoxicity scores reached statistical significance[4(3-6)for NAC,4.5(3-5)for AMF and 6(5-6)for ASC;P=0.001,P=0.001 and P<0.005vs model group respectively].Exposure to MTX also caused a significant reduction in the activities of GSH and SOD antioxidants in liver tissues[control group:3.02(2.85-3.43)μmol/g and 71.78(61.88-97.81)U/g vs model group:2.52(2.07-3.34)μmol/g and 61.46(58.27-67.75)U/g,P<0.05];however,only the NAC treatment provided significant increases in these antioxidant enzyme activities[3.22(2.54-3.62)μmol/g and 69.22(61.13-100.88)U/g,P<0.05 and P<0.01vs model group respectively].CONCLUSION:MTX-induced structural and functional damage to hepatic tissues in rats may involve oxidative stress,and cytoprotective agents(NAC>AMF>ASC)may alleviate MTX hepatotoxicity. | Sami Akbulut Hulya Elbe Cengiz Eris Zumrut Dogan Gulten Toprak Emrah Otan Erman Erdemli Yusuf Turkoz | 2014 | World Journal of Gastroenterology2014，20，29： | 3 |
| 3 | Thermischer Zellaufschlul mit Anschlieender Faulung-laboruntersuchnngen (Thermal Disinte- gration with Subsequent Digestion-lab-scale Investigation)显示文摘 | Elbing G Dunnebei| A | 1999 | Korrespondenz Abwasser1999，46，2： | 1 |
| 4 | Protective effects of melatonin and quercetin on experimental lung injury induced by carbon tetrachloride in rats显示文摘 | Taslidere E Esrefoglu M Elbe H | 2014 | Exp Lung Res2014，40，2： | 1 |
| 5 | Stability and Structure of Burner Flames显示文摘 | Lewis B yon Elbe G | 1943 | Journal of Chemical Physics1943，11，： | 1 |
| 6 | 查看详情显示文摘 | Song S D Zou X L Giruzzi G Xiao W W Ding X T Ding B J Ségui J L Elbèze D Clairet F Fenzi C Aniel T Artaud J F Basiuk V Bouquey F Magne R Corbel E the Tore Supra Team | | 0，，： | 1 |
| 7 | Dry-ice blasting for clean- ing: process, optimization and application显示文摘 | SPUR G UHLMANN E ELBING F | 1999 | Wear1999，233，： | 1 |
| 8 | Thermal disin-tegration with subsequent digestion-lab-scale investigation显示文摘 | Elbing G Dti nnebeil A | 1999 | Korrespondenz Ab-wasser1999，46，2： | 1 |
| 9 | Executive income, sales and profits 显示文摘 | Mcguire J W Chiu J S Y Elbeing A Q | 1962 | American Economic Review1962，，51： | 1 |
| 10 | A DNA vector-based RNAi techno|ogy to suppress gene expression in mamalian cells显示文摘 | Sui G Soohoo C Affar elB el al | 2002 | Proc Natl Acad Sci USA2002，99，8： | 1 |
| 11 | Histological and Biochemical Effects of Dexmedetomidine on Liver during an Inflammatory Bowel Disease显示文摘 | Gul M Kayhan B Elbe H | 2013 | Ultrastruct Pathol2013，，： | 1 |
| 12 | Thermal disintegration with subsequent digestion lab-scale investigation显示文摘 | Elbing G D u nnebeil A | 1999 | Korrespondenz Abwasser1999，46，2： | 1 |
| 13 | Chemotherapy- indue apoptosis in epithelial ovary cancer 显示文摘 | Laural J Havrilerky Ala Elb endary | 1995 | Obset and Gynec1995，85，6： | 1 |
| 14 | Executive Incomea, Sales and Profits 显示文摘 | Mcguire John S Chiu Alvaro Elbing | 1962 | American Economic Review1962，，9： | 1 |
| 15 | Exeeutive Income and Profits 显示文摘 | Meguire Chiu and Elbeing | 1962 | American Economic Review1962，，9： | 1 |
| 16 | Oxygen involvement in betanJn degradation显示文摘 | ATTOE E L VON ELBE J H | 1984 | Zeitschrift fu r Lebensmitteluntersuchung und-Forschung A1984，179，3： | 1 |
| 17 | Biotransformation of the cyanobacterial hepatotoxin Microcystin-LR, as determined by HPLC and protein phosphatase bioassay 显示文摘 | Angeline K-Y L Phillip M F Elbe E P | 1995 | Environ Sci Technol1995，29，： | 1 |
| 18 | Degradation kinetics of betanin in solutions as influenced by oxygen显示文摘 | ATTOE E L VON ELBE J H | 1982 | J Agric Food Chem1982，30，4： | 1 |
| 19 | Thermischer Zellaufschlu (mit anschlle (ender Faulung-laboruntersuchnngen (Thermal disintegration with subsequent digestion lab-scale investigation) 显示文摘 | Elbing G Dunnebeil A | 1999 | Korre-spondenz Abwasser1999，46，2： | 1 |
| 20 | Focus on ziprasidone: a review of its use in child and adolescent psychiatry 显示文摘 | Elbe D Carandang CG | 2008 | J Can Acad Child Ad- olesc Psychiatry2008，17，4： | 1 |
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