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| 1 | Dextran sodium sulfate colitis murine model: An indispensable tool for advancing our understanding of inflammatory bowel diseases pathogenesis显示文摘Inflammatory bowel diseases(IBD),including Crohn's disease and ulcerative colitis,are complex diseases that result from the chronic dysregulated immune response in the gastrointestinal tract. The exact etiology is not fully understood,but it is accepted that it occurs when an inappropriate aggressive inflammatory respon-se in a genetically susceptible host due to inciting environmental factors occurs. To investigate the path-ogenesis and etiology of human IBD,various animal models of IBD have been developed that provided indispensable insights into the histopathological and morphological changes as well as factors associated with the pathogenesis of IBD and evaluation of therapeutic options in the last few decades. The most widely used experimental model employs dextran sodium sulfate(DSS) to induce epithelial damage. The DSS colitis model in IBD research has advantages over other various chemically induced experimental models due to its rapidity,simplicity,reproducibility and controllability. In this manuscript,we review the newer publicized advances of research in murine colitis models that focus upon the disruption of the barrier function of the intestine,effects of mucin on the development of colitis,alterations found in microbial balance and resultant changes in the metabolome specifically in the DSS colitis murine model and its relation to the pathogenesis of IBD. | Derrick D Eichele Kusum K Kharbanda | 2017 | World Journal of Gastroenterology2017，23，33： | 50 |
| 2 | Spontaneous intramural duodenal hematoma in type 2B von Willebrand disease显示文摘Intramural duodenal hematoma is a rare cause of a proximal gastrointestinal tract obstruction.Presentation of intramural duodenal hematoma most often occurs following blunt abdominal trauma in children,but spontaneous non-traumatic cases have been linked to anticoagulant therapy,pancreatitis,malignancy,vasculitis and endoscopy.We report an unusual case of spontaneous intramural duodenal hematoma presenting as an intestinal obstruction associated with acute pancreatitis in a patient with established von Willebrand disease,type 2B.The patient presented with abrupt onset of abdominal pain,nausea,and vomiting.Computed tomography imaging identified an intramural duodenal mass consistent with blood measuring 4.7 cm×8.7 cm in the second portion of the duodenum abutting on the head of the pancreas.Serum lipase was 3828 units/L.Patient was managed conservatively with bowel rest,continuous nasogastric decompression,total parenteral nutrition,recombinant factorⅧ(humateP)and transfusion.Symptoms resolved over the course of the hospitalization.This case highlights an important complication of an inherited coagulopathy. | Derrick D Eichele Meredith Ross Patrick Tang Grant F Hutchins Mark Mailliard | 2013 | World Journal of Gastroenterology2013，19，41： | 3 |
| 3 | Sealing PCI tracts with ge1atin matrix hemostatic sealant(FloSea1):initial clinica1 use显示文摘 | Lee DL Uribe C Eichel L | 2004 | J Urol2004，171，21： | 1 |
| 4 | Ureteroscopel:flexible,rigid,and semirigid显示文摘 | Basillote JB Lee DI Eichel L | 2004 | Urol Clin North Am2004，31，： | 1 |
| 5 | What happens to hemostatic agents in contact with urine?An in vitro study显示文摘 | Uribe C Eichel L Khonsari S | 2005 | J Endouro12005，19，3： | 1 |
| 6 | Speckle processing method for synthetic aperture radar phase correction 显示文摘 | Eichel P H Chiglia D C Jakowartz C V | 1989 | Optics Letters1989，14，1： | 1 |
| 7 | Anesthesia techniques for cataract a survey of delegates to the Congress of the International Council of Ophthalmology, 2002显示文摘 | Eichel 1L Goldbelg I | 2005 | Clin Experiment Ophthalmol2005，33，5： | 1 |
| 8 | Three differentially expressed S-adenosylmethionine synthetases from Catharanthus roseus:molecular and functional characterization显示文摘 | Schrfder G Eichel J Breinig S | 1997 | Plant Molecular Biology1997，33，2： | 1 |
| 9 | Acute disseminating encephalomyelitis in neuromyelitis optica: closing the floodgates 显示文摘 | Eichel R Meiner Z Abramsky O | 2008 | Arch Neurol2008，65，： | 1 |
| 10 | Phase gradient autofocus-a robust tool for high resolution SAR phase correction显示文摘 | Wahl D E Eichel P H Ghiglia D C | 1994 | IEEE Trans on AES1994，30，3： | 1 |
| 11 | Compression of complex-valued SAR images显示文摘 | Eichel P Ives R W | 1999 | IEEE Trans Image Processing1999，8，： | 1 |
| 12 | Phase gradient autofocus-- A robust tool high resolution SAR phase correction显示文摘 | Wahl D E Eichel P H Ghiglia D C | 1994 | IEEE Transations on Aerospace and Electronic Systems1994，30，3： | 1 |
| 13 | Fecal microbiotatransplantation for fulminant Clostridium difficile infection inan allogeneic stem cell transplant patient显示文摘 | Neemann K Eichele DD Smith PW | 2012 | Transpl InfectDis2012，14，6： | 1 |
| 14 | Phase gradient autofocus-a robust tool for high resolution SAR phase correction显示文摘 | Wahl D E Eichel P H Ghiglia D C | 1994 | IEEE Trans on GRS1994，30，3： | 1 |
| 15 | Fibrin glue-oxidized cellulose sandwich for laparoscopic wedge resection of small renal lesions显示文摘 | Finley D S Lee D I Eichel L | 2005 | J Urol2005，173，5： | 1 |
| 16 | Phase gradient auto-focus-a robust tool for high resolution SAR phase correction 显示文摘 | WAHL D E EICHEL P H GHIGLLA D C | 1994 | IEEE Transactions on aerospace and electronic system1994，30，3： | 1 |
| 17 | Three differentially ex pressed S-adenosylmethionine synthetases from Catharanthusroseus: Molecular and functional characterization显示文摘 | Schroder G Eichel J Breining S | 1997 | Plant Molecular Biology1997，33，： | 1 |
| 18 | Phase gradient autofocus a robust tool for high resolution SAR phase correction显示文摘 | Wahl D E Eichel P H Ghiglia D C | 1994 | IEEE Trans on AES1994，30，3： | 1 |
| 19 | Impact of onco- genie K - RAS on YB - 1 phosphorylation induced by ionizing radiation显示文摘 | Toulany M Schickfluss TA Eicheler W | 2011 | Breast Cancer Research2011，13，2： | 1 |
| 20 | Robotic radical pros- tatectomy: a technique to reduce pT2 positive margins 显示文摘 | Ahlering TE Eichel L Edwards RA | 2004 | Urol- ogy2004，64，： | 1 |
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