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| 1 | WJC 6~th Anniversary Special Issues(3):Cardiomyopathy Hypertrophic cardiomyopathy in 2013:Current speculations and future perspectives显示文摘Hypertrophic cardiomyopathy(HCM),the most variable cardiac disease in terms of phenotypic presentation and clinical outcome,represents the most common inherited cardiomyopathic process with an autosomal dominant trait of inheritance.To date,more than 1400 mutations of myofilament proteins associated with the disease have been identified,most of them 'private' ones.This striking allelic and locus heterogeneity of the disease certainly complicates the establishment of phenotype-genotype correlations.Additionally,topics pertaining to patients' everyday lives,such as sudden cardiac death(SCD)risk stratification and prevention,along with disease prognosis,are grossly related to the genetic variation of HCM.This review incorporates contemporary research findings and addresses major aspects of HCM,including preclinical diagnosis,genetic analysis,left ventricular outflow tract obstruction and SCD.More specifically,the spectrum of genetic analysis,the selection of the best method for obstruction alleviation and the need for a unique and accuratefactor for SCD risk stratification are only some of the controversial HCM issues discussed.Additionally,future perspectives concerning HCM and myocardial ischemia,as well as atrial fibrillation,are discussed.Rather than enumerating clinical studies and guidelines,challenging problems concerning the disease are critically appraised by this review,highlighting current speculations and recommending future directions. | Georgios K Efthimiadis Efstathios D Pagourelias Thomas Gossios Thomas Zegkos | 2014 | World Journal of Cardiology2014，6，2： | 9 |
| 2 | Conversion coatings of Mg-alloy AZ91D using trihexyl(tetradecyl) phosphonium bis(trifluoromethanesulfonyl)amide ionic liquid显示文摘This work reveals the performance of a trihexyl(tetradecyl)phosphonium bis(trifluoromethanesulfonyl)amide ([P6,6,6,14][NTf2]) ionic liquid (IL) conversion coating upon AZ91D. Such conversion coatings represent a novel avenue for chromate replacement. An optimization of coating performance was pursued by careful alloy pretreatment to generate a surface on which the coating performs best, as the AZ91 substrate is distinctly different from pure or dilute Mg alloys. The results reveal that a functional conversion coating can be achieved, retarding anodic dissolution kinetics, causing a significant decrease in corrosion rate. The coating efficacy is closely tied to the pretreatment performed, which dictates both the microstructural and electrochemical heterogeneity of the surface. The resulting coatings were found to contain MgxFx and phosphonium cation related components, the proportions of which were dependent on the pretreatment. | HOWLETT P. C. GRAMET S. LIN J. EFTHIMIADIS J. CHEN X. B. BIRBILIS N. FORSYTH M. | 2012 | Science China Chemistry2012，55，8： | 2 |
| 3 | Measuring airway inflammation in asthma:eosinophils and eosinophilic cationic protein in induced sputum compared with peripheral blood 显示文摘 | Pizzichini E Pizzichini MM Efthimiadis A | 1997 | J Allergy Clin Immunol1997，99，4： | 1 |
| 4 | Left ventrieular outflow tract obstruction as a risk factor for sudden cardiac death in hypertrophic cardiomyopathy 显示文摘 | Efthimiadis GK Parcharidou DG Giannakoulas G | 2009 | Am J Cardiol2009，104，5： | 1 |
| 5 | Methods of sputum proces- sing for cell counts,immunocytochemistry and in situ hybridisation 显示文摘 | Efthimiadis A Spanevello A Hamid Q | 2002 | Eur Respir J Suppl2002，37，： | 1 |
| 6 | Left Ventricular Outflow Tract Obstruction as a Risk Factor for Sudden Cardiac Death in Hypertrophic Cardiomyopathy显示文摘 | Georgios K. Efthimiadis Despina G. Parcharidou Georgios Giannakoulas Efstathios D. Pagourelias Panagiotis Charalampidis Gregorios Savvopoulos Antonios Ziakas Haralambos Karvounis Ioannis H. Styliadis Georgios E. Parcharidis | 2009 | The American Journal of Cardiology2009，，5： | 1 |
| 7 | Indices of airway inflam- mation in induced sputum :reproducibility and validity of cell and fluid- phase measurements显示文摘 | Pizzichini E Pizzichini MM Efthimiadis A | 1996 | Am J Respir Crit Care Med1996，154，21： | 1 |
| 8 | 显示文摘 | Wong AG Efthimiadis A | 1996 | Am J Respir Crit Care Med1996，153，2： | 1 |
| 9 | Indices of airway inflammation in induced sputum:reproducibility and validity of cell and fluid-phase measurements显示文摘 | PIZZICHINI E PIZZICHINI M M EFTHIMIADIS A | 1996 | Am J Respir Crit Care Med1996，154，21： | 1 |
| 10 | Indices of airway inflammation in induced sputum: reproducibility and validity of cell and fluid-phase measurements 显示文摘 | Pizzichini E Pizzichini MM Efthimiadis A | 1996 | Am J Respir Crit Care Med1996，154，21： | 1 |
| 11 | Methods of sputum processing for cell counts,immunocytochemistry and in situ hybridisation显示文摘 | Efthimiadis A Spanevello A Haroid Q | 2002 | Eur Respir J Suppl2002，37，： | 1 |
| 12 | Indices of airway inflammation in induced sputum: reproducibility and validity of cell fluid phase measurements显示文摘 | Pizzichini E Pizzichini MMM Efthimiadis A | 1996 | Am J Respir Crit Care Med1996，154，3： | 1 |
| 13 | Risk factors of ischaemic heart disease and long-term outcome after coronary bypass surgery显示文摘 | Efthimiadis A Lefkos N Psirropoulos D | 2001 | J Cardiovas Surg(Torino)2001，42，6： | 1 |
| 14 | Manometric and clinical evaluation of patients after low anterior resection for rectal cancer 显示文摘 | Efthimiadis C Basdanis G Zatagias A | 2004 | Tech Coloproctol2004，8，1： | 1 |
| 15 | Induced sputum: time from expectoration to processing显示文摘 | Efthimiadis A Jayaram L Weston S | 2002 | Eur Respir J2002，19，： | 1 |
| 16 | Rosuvaststin and cardiovascular diease :did the strongest statin hold the initial promises 显示文摘 | Efthimiadis | 2008 | Apostolos Angi- ology2008，59，2： | 1 |
| 17 | 显示文摘 | Pizzichini MM Efthimiadis A | 1996 | AmJ Respir Crit Care Med1996，154，21： | 1 |
| 18 | Indices of airway inflammation in induced sputum:reproducibility and validity of cell fluid phase measurements 显示文摘 | Pizzichini E Pizzichini M M Efthimiadis A et al | 1996 | Am J Respir Crit Care Med1996，154，21： | 1 |
| 19 | Sputum CD34+IL-5Ralpha+ cells increase after allergen:evidence for insitu eosinophilo:poiesis显示文摘 | Dorman SC Efthimiadis A Babirad I | 2004 | Am J Respir Crit Care Med2004，169，5： | 1 |
| 20 | Antioxidant effects of simvastatin in primary and secondary prevention of coronary heart disease 显示文摘 | TAVRIDOU A EFTHIMIADIS A EFTHIMIADIS I | 2006 | Eur J Clin Phaln2006，62，6： | 1 |
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