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| 1 | Single-center study comparing computed tomography colonography with conventional colonoscopy显示文摘AIM:To compare the results from computed tomography (CT) colonography with conventional colonoscopy in symptomatic patients referred for colonoscopy. METHODS: The study included 227 adult outpatients, mean age 60 years, with appropriate indications for colonoscopy. CT colonography and colonoscopy were performed on the same day in a metropolitan teaching hospital. Colonoscopists were initially blinded to the results of CT colonography but there was segmental unblinding during the procedure. The primary outcome measures were the sensitivity and specificity of CT colonography for the identification of polyps seen at colonoscopy (i.e. analysis by polyp). Secondary outcome measures included an analysis by patient, extracolonic findings at CT colonography, adverse events with both procedures and patient acceptance and preference. RESULTS: Twenty-five patients (11%) were excluded from the analysis because of incomplete colonoscopy or poor bowel preparation that affected either CT colonography, colonoscopy or both procedures. Polyps and masses (usually cancers) were detected at colonoscopy and CT colonography in 35% and 42% of patients, respectively. Of nine patients with a finaldiagnosis of cancer, eight (89%) were identified by CT colonography as masses (5) or polyps (3). For polyps analyzed according to polyp, the overall sensitivity of CT colonography was 50% (95% CI, 39%-61%) but this increased to 71% (95% CI, 52%-85%) for polyps ≥ 6 mm in size. Similarly, specificity for all polyps was 48% (95% CI, 39%-58%) increasing to 67% (95% CI, 56%-76%) for polyps ≥ 6 mm. Adverse events were uncommon but included one colonic perforation at colonoscopy. Patient acceptance was high for both procedures but preference favoured CT colonography. CONCLUSION: Although CT colonography was more sensitive in this study than in some previous studies, the procedure is not yet sensitive enough for widespread application in symptomatic patients. | Ian C Roberts-Thomson Graeme R Tucker Peter J Hewett Peter Cheung Ruben A Sebben EE Win Khoo Julie D Marker Wayne K Clapton | 2008 | World Journal of Gastroenterology2008，14，3： | 4 |
| 2 | Liver transplantasion in pations with non- biliary cirrhosis:prognostic valuc of preoperative factors显示文摘 | Gonzale EE Rimola A Navasa M ct al | 1998 | J Hepatol1998，28，： | 1 |
| 3 | A feedback loop comprising lin-28 and let-7 controls pre-let-7maturation during neural stem-cell commitment 显示文摘 | Rybak A Fuchs H Smirnova L Brandt C Pohl EE Nitsch R etal | 2008 | Nat CellBioi2008，10，8： | 1 |
| 4 | Developmental anatomy of the nasolacrimal duct: implications for congenital obstruction 显示文摘 | Moscato EE Kelly JP Weiss A | 2010 | Ophthalmology2010，117，12： | 1 |
| 5 | PD173074, a selective FGFR inhibitor reverses ABCB1- mediated drug resistance in cancer cells 显示文摘 | Patel A Tiwari AK Chufan EE | 2013 | Cancer Chemother Pharmacol2013，72，1： | 1 |
| 6 | Addition of Matrix Metalloproteinase Inhibition to Conventional Cytotoxic Therapy Reduces Tumor Implantation and Prolongs Survival in a Murine Model of Human Pancreatic Cancer 显示文摘 | Hag M Shafii A Zervos EE | 2000 | Cancer Res2000，60，12： | 1 |
| 7 | EMMPRIN/CD147,an MMP modulator in cancer,development and tissue repair显示文摘 | Gabison EE Hoang-Xuan T Mauviel A | 2005 | Biochimie2005，87，34： | 1 |
| 8 | Osseous Reconstruction Using a Membrane Barrier Following Marginal Mandibulectomy:An Animal Pilot Study显示文摘 | Peled M Machtei EE Rachmiel A | 2007 | J Periodontol2007，73，12： | 1 |
| 9 | Organ injury scaling,Ⅱ:Pancreas,duodenum,small bowel,colon,and retum显示文摘 | Moore EE Cogbill TH Malangoni M A | 1990 | J Trauma1990，30，11： | 1 |
| 10 | Epidemiology of trauma deaths: a reassessment显示文摘 | Sauaia A Moore FA Moore EE | 1995 | J Trauma1995，38，： | 1 |
| 11 | EMMPRIN/CD147,an MMP modulator in cancer,develop-ment and tissue repair显示文摘 | Gabison EE Hoang-Xuan T Mauviel A Menashi S | 2005 | Biochimie2005，87，34： | 1 |
| 12 | Degenerative lumbar scoliosis as- sociated with spinal stenosis显示文摘 | Ploumis A Transfedt EE Denis F | 2007 | Spine J2007，4，： | 1 |
| 13 | Pulmonary hypertension is associated with worse early and late outcomes after aortic valve replacement:implications for transcatheter aortic valve replacement显示文摘 | Roselli EE Abdel Azim A Houghtaling PL | | 0，，05： | 1 |
| 14 | Mechanisms of renal hypore- sponsiveness to BNP in heart failure 显示文摘 | Egom EE Feridooni T Hotchkiss A et a| | 2015 | Can J Physiol Phannacol2015，93，6： | 1 |
| 15 | Estimating the relative contributions of virulence factors for pathogenic mi- crobes显示文摘 | McClelland EE Bernhardt P Casadevall A | 2006 | In1''ect Immun2006，74，3： | 1 |
| 16 | Local expression of indoleamine 2,3-dioxygenase protects engraftment of xenogeneic skin substitute显示文摘 | Tredqet EE Gaffari A | 2006 | J Invest Dermatol2006，126，： | 1 |
| 17 | Visually significant haze after retreatment w ith photorefractive keratectomy w ith mitomycin-C follow ing la-ser in situ keratomileusis显示文摘 | Liu A Manche EE | 2010 | J Cataract Refract Surg2010，36，9： | 1 |
| 18 | Distinct patterns of deletion on 10p and 10q suggest involvement of multiple tumor suppressor genes in the development of astrocytic gliomas of different malignancy grades显示文摘 | Ichimra K Schmdt EE Miyakawa A | 1998 | Genes Chromosomes Cancer1998，22，1： | 1 |
| 19 | Multiple organ failure can be predicated as early as 12 hours after injury显示文摘 | Sauaia A Moore FA Moore EE | 1998 | J Trauma1998，45，2： | 1 |
| 20 | EMMPRIN/CD147,an MMP modulator in cancer,development and tissue repair显示文摘 | Gabison EE Hoang-Xuan T Mauvie A | 2005 | Biochimie2005，87，34： | 1 |
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