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| 1 | Diagnosis of hepatocellular carcinoma显示文摘Hepatocellular carcinoma (HCC) is one of the commonest cancers worldwide, particularly in parts of the developing world, and is increasing in incidence. This article reviews the current modalities employed for the diagnosis of HCC, including serum markers, radiological techniques and histological evaluation, and summarises international guidelines for the diagnostic approach to HCC. | Asmaa I Gomaa Shahid A Khan Edward LS Leen Imam Waked Simon D Taylor-Robinson | 2009 | World Journal of Gastroenterology2009，15，11： | 44 |
| 2 | 药物不良反应:定义、诊断与管理显示文摘我们将药物不良反应定义为'药物用于防治疾病而引起可以觉察到的有害的或不利的反应,这预示着继续给药会有危险,需要预防或特定治疗措施,或减少剂量,乃至停药',这样一些反应现今以世界卫生组织不良反应术语(WHO-ART)进行报告,后者终将成为国际疾病分类(ICD)的一个组成部分. | I Ralph Edwards Jeffrey K Aronson | 2001 | 药物不良反应杂志2001，3，2： | 14 |
| 3 | Achromatic super-oscillatory lenses with subwavelength focusing显示文摘Lenses are crucial to light-enabled technologies.Conventional lenses have been perfected to achieve near-diffraction-limited resolution and minimal chromatic aberrations.However,such lenses are bulky and cannot focus light into a hotspot smaller than a half-wavelength of light.Pupil filters,initially suggested by Toraldo di Francia,can overcome the resolution constraints of conventional lenses but are not intrinsically chromatically corrected.Here we report single-element planar lenses that not only deliver sub-wavelength focusing,thus beating the diffraction limit of conventional refractive lenses,but also focus light of different colors into the same hotspot.Using the principle of super-oscillations,we designed and fabricated a range of binary dielectric and metallic lenses for visible and infrared parts of the spectrum that are manufactured on silicon wafers,silica substrates and optical fiber tips.Such low-cost,compact lenses could be useful in mobile devices,data storage,surveillance,robotics,space applications,imaging,manufacturing with light and spatially resolved nonlinear microscopies. | Guang Hui Yuan Edward TF Rogers Nikolay I Zheludev | 2017 | Light(Science & Applications)2017，6，1： | 10 |
| 4 | 半嵌套式PCR检测转几丁质酶基因烟草研究显示文摘用含卡那霉素的培养基首先对转几丁质酶基因烟草种子和烟苗进行初步筛选鉴定 ,再用 Western Blot进一步证实抗卡那霉素的转基因烟苗中外源转几丁质酶基因的表达。然后研究半嵌套式 PCR(Semi- nested PCR)检测转几丁质酶基因烟草植株及其烤后烟叶中的所转目的基因 ;利用限制性内切酶 H ind 对半嵌套式 PCR产物进行酶切 ,从而验证半嵌套式 PCR产物是否为真正的目的基因。研究结果表明 ,半嵌套式 PCR是一种快速。 | 时焦 M Naylor M L Edwards J I Cooper 韩锦峰 | 2002 | 中国烟草学报2002，8，2： | 8 |
| 5 | Two-dimensional control of light with light on metasurfaces显示文摘The ability to control the wavefront of light is fundamental to focusing and redistribution of light,enabling many applications from imaging to spectroscopy.Wave interaction on highly nonlinear photorefractive materials is essentially the only established technology allowing the dynamic control of the wavefront of a light beam with another beam of light,but it is slow and requires large optical power.Here we report a proof-of-principle demonstration of a new technology for two-dimensional(2D)control of light with light based on the coherent interaction of optical beams on highly absorbing plasmonic metasurfaces.We illustrate this by performing 2D all-optical logical operations(AND,XOR and OR)and image processing.Our approach offers diffractionlimited resolution,potentially at arbitrarily-low intensity levels and with 100 THz bandwidth,thus promising new applications in space-division multiplexing,adaptive optics,image correction,processing and recognition,2D binary optical data processing and reconfigurable optical devices. | Maria Papaioannou Eric Plum João Valente Edward TF Rogers Nikolay I Zheludev | 2016 | Light(Science & Applications)2016，5，1： | 3 |
| 6 | Studies on the anti-asthmatic and antitussive properties of aqueous leaf extract of Bryophyllum pinnatum in rodent species显示文摘Objective:To evaluate the antiasthmatic and antitussive properties of the aqueous leaf extract of Bryophyilum pinnatum {B.pinnatum)(BP) Lam.Methods:Ovalbiunin-sensilized guinea pigs which were treated with BP for 21 consecutive days were exposed to 0.2%histamine aerosol in a glass chamber.Mucus viscosity,white blood cell and lymphocyte counts and tracheal wall morphometry were measured.Bouts of cough were counted pre and post acute exposure of extract-treated(X7 d) guinea pigs to 7.5%citric acid aerosol in a chamber.Phenol red expectoration was estimated in mice after 7 d of daily administration of BP.Results:Doses of 200 and 400 mg/kg/day(×21 d) BP significantly increased the time for guinea pigs to experience preconvulsive dyspnoea.BP and salbutamol(0.5 mg/kg/day×21 d) reduced mucus viscosity in the sensitized group to values comparable with controls.White blood cell,lymphocyte counts and tracheal morphometry were not significantly altered.Both doses of BP also significantly reduced the bouts of cough but only 400 mg/kg/day significantly inhibited the amount of phenol red secreted.Conclusions:BP has demonstrated antiasthmatic and antitussive properties in these rodent models.These properties may underscore its use in Nigerian ethnomedicine. | Edward O Salami Raymond I Ozolua Stephen O Okpo Gerald I Eze Dickson O Uwaya | 2013 | Asian Pacific Journal of Tropical Medicine2013，6，6： | 2 |
| 7 | Strategies to tackle the challenges of external beam radiotherapy for liver tumors显示文摘Primary and metastatic liver cancer is an increasingly common and difficult to control disease entity.Radiation offers a non-invasive treatment alternative for these patients who often have few options and a poor prognosis.However,the anatomy and aggressiveness of liver cancer poses significant challenges such as accurate localization at simulation and treatment,management of motion and appropriate selection of dose regimen.This article aims to review the options available and provide information for the practical implementation and/or improvement of liver cancer radiation programs within the context of stereotactic body radiotherapy and image-guided radiotherapy guidelines.Specific patient inclusion and exclusion criteria are presented given the significant toxicity found in certain sub-populations treated with radiation.Indeed,certain sub-populations,such as those with tumor thrombosis or those with larger lesions treated with transarterial chemoembolization,have been shown to have significant improvements in outcome with the addition of radiation and merit special consideration.Implementing a liver radiation programrequires three primary challenges to be addressed:(1) immobilization and motion management;(2) localization;and(3) dose regimen and constraint selection.Strategies to deal with motion include simple internal target volume(ITV) expansions,non-gated ITV reduction strategies,breath hold methods,and surrogate marker methods to enable gating or tracking.Localization of the tumor and organs-at-risk are addressed using contrast infusion techniques to take advantage of different normal liver and cancer vascular anatomy,imaging modalities,and margin management.Finally,a dose response has been demonstrated and dose regimens appear to be converging.A more uniform approach to treatment in terms of technique,dose selection and patient selection will allow us to study liver radiation in larger and,hopefully,multicenter randomized studies. | Michael I Lock Jonathan Klein Hans T Chung Joseph M Herman Edward Y Kim William Small Nina A Mayr Simon S Lo | 2017 | World Journal of Hepatology2017，9，14： | 2 |
| 8 | A novel dual - phase culture medium promotes germination and seedling establishment from immature embryos in South African Disa ( Orchidaceae ) species 显示文摘 | Thompson D I Edwards T J van Staden J | 2007 | Plant Growth Regul2007，53，3： | 1 |
| 9 | Effect of feeding tuna oil or soybean oil as supplements to sows in late pregnancy on piglet tissue composition and piglet Viability显示文摘 | Rooke J A Bland I M Edwards S A | 1998 | British Journal of Nutrition1998，80，： | 1 |
| 10 | Do viscous polysaccharides slow absorption by inhibiting diffusion or convection?显示文摘 | Edwards C A Johnson I T Read N W | 1988 | European Journal of Clinical Nutrition1988，42，： | 1 |
| 11 | Fault diagnosis of rotating machinery 显示文摘 | EDWARDS S LEES A W FRISWELL M I | 1998 | Shock and Vibration Digest1998，30，1： | 1 |
| 12 | Variations in methane and nitrous oxide mixing ratios at the southern boundary of a Canadian boreal forest 显示文摘 | Simpson I J Edwards G C Thurtell G W | 1999 | Atmospheric Environment1999，33，7： | 1 |
| 13 | Adverse drug reactions:defini- tions, diagnosis, and management 显示文摘 | EDWARDS I R ARONSON J K | 2000 | Lancet2000，356，9237： | 1 |
| 14 | RF fiber-optic link performance显示文摘 | Edward I Ackerman Charles H Cox | 2001 | IEEE microwave magazine2001，，： | 1 |
| 15 | Characterization of cDNA encoding two isoforms of granule boung starch synthase which show differetial expression in developing storage organs of pea and potato显示文摘 | Dry I Smith A Edward A | 1992 | Plant Journal1992，，2： | 1 |
| 16 | Ameloblastic carci- noma: a clinicopathologic study and assessment of eight cases显示文摘 | Corio R L Goldblatt L I Edwards P A | 1987 | Oral Surg Oral Med Oral Pathol1987，64，5： | 1 |
| 17 | Membrane ther- mostability and heat tolerance of spring wheat 显示文摘 | Shanahan J F Edwards I B Quick J S | 1990 | Crop Sci- ence1990，30，2： | 1 |
| 18 | OMEGA EP high-energy petawatt laser: progress and prospects显示文摘 | D N Maywar J H Kelly L J Waxer S F B Morse I A Begishev J Bromage C Dorrer J L Edwards L Folnsbee M J Guardalben S D Jacobs R Jungquist T J Kessler R W Kidder B E Kruschwitz S J Loucks J R Marciante R L McCrory D D Meyerhofer A V Okishev J B Oliver G Pien | 2008 | Journal of Physics: Conference Series2008，，3： | 1 |
| 19 | Low molecular weight organic acids adsorption in forest soils: effects on soil solution concentrations and biodegradation rates显示文摘 | VAN HEES P A W VINOGRADOFF S I EDWARDS A C | 2003 | Soil Biology & Biochemistry2003，35，： | 1 |
| 20 | Studies on tile biotin requirement of broiler breeders 显示文摘 | Brewer I E Edwards It M Jr | 1972 | Poultry Sci1972，51，： | 1 |
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