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| 1 | 胰岛素生成,胰岛素分泌及2型糖尿病:问题的核心在于β细胞(英文)显示文摘近年来,有人将2型糖尿病(T2DM)定义为由胰岛素抵抗引起的一种疾病,作为代谢综合征的一部分。胰岛素抵抗确实存在于T2DM,但同时也以同样程度存在于许多并无糖尿病的人群中,这些人可有或无代谢综合征。因而单独胰岛素抵抗不可能是T2DM的决定性致病因素。T2DM从其最早的阶段包括糖耐量受损(IGT)及空腹血糖受损(IFG),甚或在可测出的这些血糖变化之前的“糖尿病前期”就出现胰岛素释放动力学的障碍;其主要特征是对葡萄糖反应的胰岛素释放第一相丧失,随之而来的是逐渐加重的第二相胰岛素和总胰岛素分泌的受损。第一相胰岛素反应丧失的后果为肝脏未能迅速胰岛素化,延迟了对肝葡萄糖输出的抑制,从而引起餐后高血糖。在某些研究中,确已发现T2DM时β细胞量总体的减少,但并非所有研究中都有此同样结果,故对此尚须进一步证实。现已明确,糖尿病易发人群的β细胞的分泌适应能力是有限的,在胰岛素抵抗或热量负荷对胰岛素释放要求增加时,就难以胜任。此外,即使轻度的高血糖也会严重影响胰岛素的分泌并减少胰岛素原的合成,从而使代谢所需的胰岛素进一步减少。转录因子PDX-1在此损伤过程中起关键作用。因而,及早并有效地将T2DM血糖控制于接近正常水平至关重要,尤其是对胰岛素一相分泌的恢复更是如此。 | Erol Cerasi | 2005 | 中华内分泌代谢杂志2005，21，3： | 85 |
| 2 | 基于颗粒真实几何形状的铁路道砟剪切过程三维离散元分析显示文摘铁路道床由尺寸和形状各异的道砟颗粒组成,道砟颗粒的形状对道床的强度、变形等力学特性具有显著影响,反映颗粒单一方向尺寸分布特征的级配曲线难以全面描述形状不规则的道砟颗粒的几何特征。该文利用计算机视觉成像技术获得道砟颗粒在三个相互垂直方向的投影图,提取投影图轮廓并计算其几何特征参数;基于颗粒三视图重建与真实道砟颗粒具备相同几何特征的三维模型,引入到自行开发的三维块体离散元数值模拟程序中,建立了真实道砟颗粒料的三维离散元分析模型。通过与多种竖向压力作用下的室内直剪试验结果进行对比,验证了该方法可靠性;并在此基础上对道砟颗粒料在直剪试验中的变形和细观力学特性进行了深入详细的分析。 | 边学成 李伟 李公羽 Erol Tutumluer | 2015 | 工程力学2015，32，5： | 34 |
| 3 | Tumors of the spine显示文摘Spine tumors comprise a small percentage of reasons for back pain and other symptoms originating in the spine.The majority of the tumors involving the spinal column are metastases of visceral organ cancers which are mostly seen in older patients.Primary musculoskeletal system sarcomas involving the spinal column are rare.Benign tumors and tumor-like lesions of the musculoskeletal system are mostly seen in young patients and often cause instability and canal compromise.Optimal diagnosis and treatment of spine tumors require a multidisciplinary approach and thorough knowledge of both spine surgery and musculoskeletal tumor surgery.Either primary or metastatic tumors involving the spine are demanding problems in terms of diagnosis and treatment.Spinal instability and neurological compromise are the main and critical problems in patients with tumors of the spinal column.In the past,only a few treatment options aiming short-term control were available for treatment of primary and metastatic spine tumors.Spine surgeons adapted their approach for spine tumors according to orthopaedic oncologic principles in the last 20 years.Advances in imaging,surgical techniques and implant technology resulted in better diagnosis and surgical treatment options,especially for primary tumors.Also,modern chemotherapy drugs and regimens with new radiotherapy and radiosurgery options caused moderate to long-term local and systemic control for even primary sarcomas involving the spinal column. | Mert Ciftdemir Murat Kaya Esref Selcuk Erol Yalniz | 2016 | World Journal of Orthopedics2016，7，2： | 13 |
| 4 | Nature:研究鉴定出蛋白Nlrp9b抵抗轮状病毒感染机制显示文摘轮状病毒(rotavirus)是婴儿和儿童罹患肠胃炎和腹泻的一种最为常见的原因,每年导致全世界大约21.5万人死亡。它是高度传染性的和潜在致命性的。这种病毒特异性地感染宿主小肠中的肠上皮细胞,并且已进化出抵抗干扰素和NF-KB信号的策略来躲避免疫系统,这就提出一个问题:其他的宿主因子是否参与肠道粘膜中的抗病毒反应。不过,针对体内(特别是通过NLR炎性体)检测和限制肠道病毒的机制,人们知之甚少。 | Shu Zhu, Zheng Wei, Noah W. Palm, Yi Yang, Hua Yu, Hua-Bing Li, Geng Wang, Xuqiu Lei, Marcel R. de Zoete, Jun Zhao, Yunjiang Zheng, Haiwei Chen, Liang Shan, Richard A. Flavell Siyuan Ding, Ningguo Feng, Harry B. Greenberg Siyuan Ding, Harry B. Greenberg Penghua Wang, Yujiao Zhao Wen Pan, Jun Lu Jun Zhao, Yuval Kluger Kellie A. Jurado, Clara Abraham, Erol Fikrig Erol Fikrig, Richard A. Flavell | 2017 | 现代生物医学进展2017，17，27： | 10 |
| 5 | Levels of matrix metalloproteinase-1 and tissue inhibitors of metalloproteinase-1 in gastric cancer显示文摘AIM:To evaluate the levels of preoperative serum matrix metalloproteinase-1 (MMP-1) and tissue inhibitor of metalloproteinase-1 (TIMP-1) in gastric cancer.METHODS:One hundred gastric cancer patients who underwent gastrectomy were enrolled in this study.The serum concentrations of MMP-1 and TIMP-1 in these patients and in fifty healthy controls were determined using an enzyme-linked immunosorbent assay.RESULTS:Higher serum MMP-1 and TIMP-1 levels were observed in patients than in controls (P < 0.001).Serum MMP-1 and TIMP-1 levels were positively associated with morphological appearance,tumor size,depth of wall invasion,lymph node metastasis,liver metastasis,perineural invasion,and pathological stage.They were not significantly associated with age,gender,tumor location,or histological type.CONCLUSION:Increased MMP-1 and TIMP-1 were associated with gastric cancer.Although these markers are not good markers for diagnosis,these markers show in advanced gastric cancer. | Ozgur Kemik Ahu Sarbay Kemik Aziz Sümer Ahmet Cumhur Dulger Mine Adas Huseyin Begenik Ismail Hasirci Ozkan Yilmaz Sevim Purisa Erol Kisli Sefa Tuzun Cetin Kotan | 2011 | World Journal of Gastroenterology2011，17，16： | 10 |
| 6 | 伯氏疏螺旋体传播过程中病原体、媒介、宿主间的相互作用(英文)显示文摘莱姆病是一种蜱媒传播的人兽共患病,在北半球广泛流行。其病原体是伯氏疏螺旋体,具有极为复杂的传播机制和过程。在过去20多年中,科学家们对此进行了广泛而深入的探索。本综述拟对近5年这方面的研究进展,尤其是Fikrig实验室的工作进行总结。内容主要包括:证明伯氏疏螺旋体外膜蛋白OspA是一种粘附素(adhesion) ,对螺旋体在硬蜱中肠(midgut)定居至关重要,并发现硬蜱中肠肠腔表面蛋白TROSPA是OspA的受体;发现蜱唾液腺蛋白Salp15协助伯氏疏螺旋体感染哺乳类动物;发现伯氏疏螺旋体膜蛋白bmpA和bmpB介导螺旋体在关节的定居及关节炎的发生。这些发现有助于我们深入了解莱姆病的传播特征和致病机制。 | 宝福凯 Erol Fikrig | 2008 | 中国媒介生物学及控制杂志2008，19，3： | 9 |
| 7 | Gallbladder function and dynamics of bile flow in asymptomatic gallstone disease显示文摘AIM:To investigate the effects of gallbladder stones on motor functions of the gallbladder and the dynamics of bile flow in asymptomatic gallstone disease.METHODS:Quantitative hepatobiliary scintigraphy was performed to detect the parameters of gallbladder motor function [gallbladder ejection fraction(GBEF),gallbladder visualization time(GBVT),gallbladder time to peak activity(GBTmax),gallbladder half emptying time(GBT1/2),and transit time of bile to duodenum(TTBD)] in 24 patients with asymptomatic cholelithiasis who were diagnosed incidentally during routine abdominal ultrasonographic examination and 20 healthy subjects with normal gallbladder.RESULTS:Even though there was no significant difference in the clinical and laboratory parameters between the patient and control groups,all parameters of gallbladder function except TTBD were found to differ significantly between the two groups.GBEF in the patient group was decreased(P=0.000) and GBVT,GBTmax,GBT1/2 in the patient group were longer(P=0.000,P=0.015,P=0.001,respectively).CONCLUSION:Our results showed that even if there were not any clinical and laboratory findings,gallbladder filling and emptying could be impaired in patients with gallstone disease. | Sevim Süreyya eri Feride Meltem zbek Celal eri Bahattin Baykal Hasan Erol Eroglu Zeynep Baykal Mustafa Yildiz Semahat Saglam Ahmet Yesildag | 2009 | World Journal of Gastroenterology2009，15，22： | 8 |
| 8 | Gastric polypoid lesions:Analysis of 150 endoscopic polypectomy specimens from 91 patients显示文摘AIM: To analyze gastric polypoid lesions in our patientpopulation with respect to histopathologic features and demographic, clinical, and endoscopic characteristics of patients.METHODS: Clinical records and histopathologic reports of patients with gastric polypoid lesions were analyzed retrospectively. All lesions had been totally removed by either endoscopic polypectomy or hot biopsy forceps. The histopathologic slides were re-evaluated by the same histopathologist.RESULTS: One-hundred and fifty gastric polypoid lesions were identified in 91 patients. There were 53 (58%) women and 38 (42%) men with a median age of 53 (range, 31 to 82) years. The most frequent presenting symptom was dyspepsia that was observed in 35 (38.5%) patients.Symptoms were mostly related to various associated gastric abnormalities such as chronic gastritis or H pylori infection rather than polypoid lesion itself. Polypoid lesions were commonly located in the antrum followed by cardia. Out of 150 lesions, 80 (53%) had the largest dimensions less than or equal to 5 mm and only 7 were pedunculated. The frequencies of hyperplastic polyps, foveolar hyperplasia, and fundic gland polyps were 46%, 18%, and 14% respectively.We also detected gastritis varioliformis in 12 specimens,lymphoid follicles in 9, 4 adenomatous polyps in 4, polypoid lesions with edematous mucosa in 4, inflammatory polyps in 3, and carcinoid tumor in 1. Adenomatous changes were observed within two hyperplastic polyps and low grade dysplasia in one adenoma. Histopathologic evaluation of the surrounding gastric mucosa demonstrated chronic gastritis in 72 (79%) patients and H pylori infection in 45 (49%).CONCLUSION: Hyperplastic polyps are the most frequently encountered subtype of gastric polypoid lesions. They are usually associated with chronic gastritis or H pylori gastritis. Contrary to the previous belief, they may harbour adenomatous changes or dysplastic foci.Therefore, endoscopic polypectomy seems as a safe and fast procedure for both diagnosis and treatment of gastric polypoid lesions at the same session. In addition,edematous mucosa may appear misleadingly as a polypoid lesion in some instances and it can be ruled out only by histopathologic examination. | Rasim Gencosmanoglu Ebru Sen-Oran Ozlem Kurtkaya-Yapicier Erol Avsar Aydin Sav Nurdan Tozun | 2003 | World Journal of Gastroenterology2003，9，10： | 8 |
| 9 | 伯氏疏螺旋体与嗜吞噬细胞无浆体混合感染的实验研究显示文摘目的应用动物模型探讨蜱传病原体伯氏疏螺旋体和嗜吞噬细胞无浆体混合感染对组织螺旋体载量、莱姆关节炎严重性、宿主免疫功能的影响。方法建立伯氏疏螺旋体和嗜吞噬细胞无浆体混合感染和伯氏疏螺旋体单一感染小鼠模型,在不同时间点研究各组小鼠组织中的螺旋体载量、关节炎严重性和血清IgG效价,并对数据进行统计学分析。结果与单一感染组相比,在螺旋体感染后18d和30d,混合感染组小鼠组织螺旋体载量显著增高,关节炎明显严重,血清IgG效价显著偏低。结论伯氏疏螺旋体和嗜吞噬细胞无浆体混合感染显著增加小鼠组织螺旋体载量、加重关节炎症状和病理改变,且抑制体液免疫功能。 | 宝福凯 Erol Fikrig | 2007 | 热带医学杂志2007，7，3： | 7 |
| 10 | Comparison of non-cycloplegic photorefraction,cycloplegic photorefraction and cycloplegic retinoscopy in children显示文摘AIM: To compare the results of noncycloplegic photorefraction, cycloplegic photorefraction and cycloplegic refraction in preschool and non-verbal children.METHODS: One hundred and ninety-six eyes of 98children(50 females, 48 males) were included in the study. Firstly, non-cycloplegic photorefraction was achieved with Plusoptix A09; secondly, cycloplegic photorefraction was carried out with Plusoptix A09 after10 min cyclopentolate. Finally, 30 min after instillation of twice cyclopentolate, cycloplegic refraction was obtained with autorefraction and/or standard retinoscopy. Spheric equivalent, spheric power, cylindric power and cylindrical axis measurements were statistically compared.RESULTS: The mean age was 28.8±18.5mo(range12-72mo). The differences in spherical equivalent, spheric power and cylindrical power measured by the three methods were found statistically significant(P <0.05).The spherical equivalent and spheric power measured by cycloplegic photorefraction were statistically higher than the measurements of the other methods(P <0.05). The cylindrical power measured by cycloplegic refraction was statistically lower than the measurements of the photorefraction methods(P <0.05). There was no significant difference in cylindrical axis measurements between three methods(P >0.05).CONCLUSION: For the determination of refractive errors in children, the Plusoptix A09 measurements give incorrect results after instillation of cyclopentolate.Additionally, the cylindrical power measured by Plusoptix A09 with or without cycloplegia is higher. However, the non-cycloplegic Plusoptix A09 measures spheric equivalent and spheric power similar to cycloplegic refraction measurements in preschool and non-verbal children. | Ozdemir Ozdemir Zuhal Ozen Tunay Ikbal Seza Petricli Damla Ergintürk Acar Muhammet Kazim Erol | 2015 | International Journal of Ophthalmology(English edition)2015，8，1： | 6 |
| 11 | 伯氏螺旋体在小鼠宿主中的关节特异性转录谱(英文)显示文摘目的建立伯氏疏螺旋体感染的小鼠模型,研究伯氏疏螺旋体在小鼠关节组织中的关节特异性基因表达谱。方法首先,建立伯氏疏螺旋体感染小鼠模型,在不同时间点处死小鼠,收集小鼠关节、心脏、皮肤和膀胱组织,从四种组织中分别提取总RNA;随后,用DECAL技术和微阵列技术分析不同时间点伯氏疏螺旋体在四种组织中的转录组;最后,将伯氏疏螺旋体在关节中的转录组依次与其他三种组织中的转录组进行比较,找出仅在关节中表达的伯氏疏螺旋体基因,从而获得伯氏疏螺旋体不同时间点的关节特异性基因表达谱。结果与其他组织相比,在感染后第15天,伯氏疏螺旋体在小鼠关节组织特异地表达21个基因,其中13个基因位于伯氏疏螺旋体染色体上,8个基因位于质粒上;在感染后的第105天,伯氏疏螺旋体在小鼠关节组织特异地表达24个基因,其中13个基因位于伯氏疏螺旋体染色体上,11个基因位于质粒上。结论伯氏疏螺旋体在小鼠关节组织中存在独特的基因表达谱,这些在关节中特异表达的基因可能与莱姆关节炎的发生、发展有关。 | 宝福凯 Erol Fikerig | 2008 | 科技通报2008，24，6： | 6 |
| 12 | 振动荷载下级配碎石颗粒运动及其能量特征试验研究显示文摘大空隙级配碎石因其良好的透(排)水性能逐渐用作“海绵城市”路面结构的基层填料,但振动荷载作用下填料颗粒在重新排列过程中的运动姿态变化以及能量状态空间分布规律仍不明确。文章基于颗粒堆积理论设计了不同级配的碎石填料,开展不同激振参数组合下的室内新型平板振动压实试验,在试样内部不同位置处放置新型智能颗粒传感器(SmartRock)实时监测压实过程中颗粒的运动姿态变化,由颗粒加速度响应分析填料内部运动能量的时空演变规律,进而提出基于颗粒运动和能量分布的填料压实质量评价新指标。研究结果表明,级配碎石填料振动压实过程可明显分为两个不同阶段:第一阶段大部分能量耗散于碎石颗粒的竖向运动及空隙的压缩,占主导的颗粒竖向运动未形成致密的骨架结构;第二阶段颗粒主要发生水平面内的平动以及竖直面内的滚动,颗粒的长轴取向逐渐趋近于“平躺”状态,大部分能量耗散于颗粒间空隙的填充,颗粒逐渐互相紧密咬合嵌挤并形成稳定的骨架结构。试样中上部颗粒的运动指标可较好地评判压实状态,当颗粒水平向运动能量从逐渐增大过渡到逐渐减小至几乎没有任何能量分布但竖向能量分布突增时,表明试样已达到较优的压实状态,新的颗粒运动和能量指标可为连续压实质量智能评价和调控技术研究提供有益的理论依据和研究基础。 | 肖源杰 王萌 于群丁 华文俊 姜钰 Tutumluer Erol | 2023 | 土木工程学报2023，56，3： | 5 |
| 13 | Driver sleepiness,fatigue,careless behavior and risk of motor vehicle crash and injury:Population based case and control study显示文摘Background: A few studies have been conducted to determine the relationship between road motor vehicle crashes(MVC) and serious injuries related to tiredness, fatigues and sleeping.Aim: To determine the effects of aggressive behaviour, driver sleepiness and fatigue on MVC and related injuries among Turkish population.Design and setting: Population-based case and control study conducted at the accident emergency departments of hospitals and roads.Subjects: 515 car drivers involved in crashes with injury were admitted to hospital and 1030 car drivers involved while driving on public roads as control group during the study period.Methods: The Manchester driver behaviour questionnaire(DBQ) measured the aberrant driving behaviours leading to accidents. Participants completed a fatigue severity scale(FSS) and Stanford Sleeping questionnaire an epworth scale with items related to sociodemographic information, driving experiences, adherence to traffic laws(such as speed limits and seat belt), and drivers' driving records.Results: In a representative sampling, participant's age ranged from 25 to 65 and the mean and standard deviation were 36.5 ± 7.8 for cases and 37.0 ± 8.0 for controls. There was a significant difference in both group of drivers regarding BMI, level of education, marital status, driving experience, seat belt use, excessive speed limits, physical activity number of sleeping hours, mobile phone use, and cigarette smoking habit(p = 0.017). Also, there was a significant higher mean score on all the DBQ violation questions among case group in comparison with the control group(p < 0.001). Further, cases had higher prevalence of Epworth sleeping disorders(p < 0.001) and fatigue severity(p = 0.003) compared to control drivers. Multivariate logistic regression revealed that excessive speed, fatigue, lapses, errors, Stanford sleepiness score, violations, mobile phone use and Epworth sleepiness scale were significantly associated with injury involvement in vehicle crash, after adjusting for driving experience and annual mileage.Conclusion: The current study confirmed that drivers with chronic fatigue, acute sleepiness,and careless driver behavior may significantly increases the risk of road crash which can be lead to serious injury. | Abdulbari Bener Erol Yildirim Turker Ozkan Timo Lajunen | 2017 | Journal of Traffic and Transportation Engineering(English Edition)2017，4，5： | 5 |
| 14 | Compressive fatigue behavior and failure evolution of additive fiber-reinforced cemented tailings composites显示文摘The ordinary cemented tailings backfill(CTB)is a cement-based composite prepared from tailings,cementitious materials,and water.In this study,a series of laboratory tests,including uniaxial compression,digital image correlation measurement,and scanning electron microscope characteristics of fiber-reinforced CTB(FRCTB),was conducted to obtain the uniaxial compressive strength(UCS),failure evolution,and microstructural characteristics of FRCTB specimens.The results show that adding fibers could increase the UCS values of the CTB by 6.90%to 32.76%.The UCS value of the FRCTB increased with the increase in the polypropylene(PP)fiber content.Moreover,the reinforcement effect of PP fiber on the CTB was better than that of glass fiber.The addition of fiber could increase the peak strain of the FRCTB by0.39%to 1.45%.The peak strain of the FRCTB increased with the increase in glass fiber content.The failure pattern of the FRCTB was coupled with tensile and shear failure.The addition of fiber effectively inhibited the propagation of cracks,and the bridging effect of cracks by the fiber effectively improved the mechanical properties of the FRCTB.The findings in this study can provide a basis for the backfilling design and optimization of mine backfilling methods. | Jiajian Li Shuai Cao Erol Yilmaz Yunpeng Liu | 2022 | International Journal of Minerals,Metallurgy and Materials2022，29，2： | 5 |
| 15 | Coagulation of a giant hemangioma in glans penis with holmium laser显示文摘在也引起一个可勃起的机能障碍(编辑) 那的龟头上与一个扩大的巨大的缝血管瘤介绍的一个 21 岁的人部分对 intracavernous 注射刺激测试作出回应。尽管在磁性的回声成像(MRI ) 的调查结果显示了一个腺的缝血管瘤,阴茎有颜色的 Doppler 超声揭示了一个入侵的 cavernausal 缝血管瘤到龟头。外科的切除根据腺损害的宽广延期被避免。钬激光凝结由于化妆联盟者担心被用于损害。然而,在钬激光申请不是出色的以后,化妆品是没有改进,在 intracavernous 注射刺激测试期望结果。在结论,钬激光申请不应该习惯于与阴茎海绵体有关的龟头的 heman-giomas,但是进一步的研究被需要在限制为龟头的小缝血管瘤揭示钬激光申请的效果。 | Emin Aydur Bulent Erol Lutfi Tahmaz Hasan Cem Irkilata Cenker Eken Ahmet Fuat Peker | 2008 | Asian Journal of Andrology2008，10，5： | 4 |
| 16 | 老年男性勃起功能及迟发性性腺功能减退症状与下尿路症状严重性的关系显示文摘本文旨在研究土耳其爱琴海地区的老年男性下尿路症状(LUTSs)、勃起功能障碍(ED)和有症状的迟发性性腺功能减退症(SLOH)三者间的关系。符合以下标准的500名男性患者被纳入该研究:40周岁以上;过去6个月内有稳定的性关系;在六个泌尿外科诊所之一进行过就诊登记。每位患者均行血清PSA、睾酮水平及尿流率的检测,并填写国际前列腺症状评分和生活质量评分(IPSS-QoL)量表、国际勃起功能指数(IIEF)问卷和老年男性症状(AMS)量表。在所有的研究对象中,23.9%的患者有轻度LUTSs,53.3%有中度LUTSS,22.8%有重度LUTSS。每组间总睾酮水平无明显差异。除此之外,69.6%的病人患有ED,且ED的发生率与LUTS严重性呈正相关。71.2%的患者出现SLOH(AMS〉27),且IPSS评分越高,严重的性腺功能减退症状的发生率也越高。相关性分析显示以上三种问卷分数之间有显著关联。总之,LUTS严重性是ED和SLOH的非年龄依赖性危险因素,LUTS严重性和SLOH症状之间似乎有显著的相关性,但还需要从病因学和生物学角度进行深入阐明。 | Ozan Bozkurt Deniz Bolat Omer Demir Oktay Ucer Ali Sahin Burak Ozcift Abdulkadir Pekta Tahir Turan Bilal H Gümü Ertan Cans Ahmet Bolukbasi Haluk Erol Adil Esenx | 2013 | Asian Journal of Andrology2013，15，6： | 4 |
| 17 | Presence of Fragmented QRS Complexes in Patients with Obstructive Sleep Apnea Syndrome显示文摘 | Muhammet Rasit Sayin Murat Altuntas Ziyaeddin Aktop Ibrahim I Oz Nesimi Yavuz Ibrahim Akpinar Erol Sagatli Turgut Karabag Mustafa Aydin | 2015 | Chinese Medical Journal2015，，16： | 4 |
| 18 | Hepatic cystic echinococcosis:Percutaneous treatment as an outpatient procedure显示文摘Objective:To demonstrate utility and safety of the puncture aspiration injection and reospiration(PAIR)technique for outpatients.Methods:Percutaneous treatment with US guidance was applied to 33 patients for 44 cysts.Patients treated with the PAIR technique,were outpatients.PAIR and catheterization technique were evaluated for efficacy and safety of procedure and complication rates.Results:Thirty-five of 44 cysts were treated with the PAIR and 9 of 44 were treated with the catheterization technique.The success rate of the cysts Gharbi type 1(CEI)and type 2(Ct3a)treated with the PAIR technique was 1009.hi the follow up of 9 cysts treated with the catheterization technique,2 of them(22%)developed cyst infection and 1(11%)developed a biliary fistula.Conclusions:The PAIR technique was found to be an effective and safe approach in order to treat Gharbi type 1 and type 2 cysts percutaneously for outpatients.It has a very low complication rate in comparison with the catheterization technique.So every effort should be mode to finish the treatment with PAIR technique. | Mert Kroglu Bekir Erol Cemil Gürses Baris Türkbey Cem Yunus Bas Ahmet Sükrü Alparslan Banu Kale Kroglu Iclal Erdem Toslak Bülent eki Okan Akhan | 2014 | Asian Pacific Journal of Tropical Medicine2014，7，3： | 4 |
| 19 | General characteristics of patients with electrolyte imbalance admitted to emergency department显示文摘BACKGROUND:Fluid and electrolyte balance is a key concept to understand for maintaining homeostasis,and for a successful treatment of many metabolic disorders.There are various regulating mechanisms for the equilibrium of electrolytes in organisms.Disorders of these mechanisms result in electrolyte imbalances that may be life-threatening clinical conditions.In this study we defined the electrolyte imbalance characteristics of patients admitted to our emergency department.METHODS:This study was conducted in the Emergency Department(ED) of Uludag University Faculty of Medicine,and included 996 patients over 18 years of age.All patients had electrolyte imbalance,with various etiologies other than traumatic origin.Demographic and clinical parameters were collected after obtaining informed consent from the patients.The ethical committee of the university approved this study.RESULTS:The mean age of the patients was 59.28±16.79,and 55%of the patients were male.The common symptoms of the patients were dyspnea(14.7%),fever(13.7%),and systemic deterioration(11.9%);but the most and least frequent electrolyte imbalances were hyponatremia and hypermagnesemia,respectively.Most frequent findings in physical examination were confusion(14%),edema(10%) and rales(9%);and most frequent pathological findings in ECG were tachycardia in24%,and atrial fibrillation in 7%of the patients.Most frequent comorbidity was malignancy(39%).Most frequent diagnoses in the patients were sepsis(11%),pneumonia(9%),and acute renal failure(7%).CONCLUSIONS:Electrolyte imbalances are of particular importance in the treatment of ED patients.Therefore,ED physicians must be acknowledged of their fluid-electrolyte balance dynamics and general characteristics. | Arif Kadri Balci Ozlem Koksal Ataman Kose Erol Armagan Fatma Ozdemir Taylan Inal Nuran Oner | 2013 | World Journal of Emergency Medicine2013，4，2： | 3 |
| 20 | Coronary embolism in a patient with mitral valve prosthesis:successful management with tirofiban and half-dose tissue-type plasminogen activator显示文摘Coronary embolism has been considered as a rarecause of coronary occlusion.Prosthetic heart valve isan infrequent cause of this condition.The exact incidenceof coronary embolization in patients with prosthetic heartvalves is not well known.Furthermore,the effectivetreatment and management of coronary emboli in | Yusuf Atmaca Cagdas Ozdol Cetin Erol | 2007 | Chinese Medical Journal2007，，24： | 3 |
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