|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 导致儿童期肥胖的生命早期危险因素:队列研究显示文摘目的确定早年(3岁以内)导致英国儿童肥胖的危险因素。设计前瞻性队列研究。方法Avon英国父母及儿童纵向调查研究。参与者参与队列研究的8234名年龄为7岁的儿童以及亚组的909名重点儿童,后者需额外提供与早期发育有关并涉及可能导致肥胖的各种资料。诊断标准7岁儿童体重指数≥95百分位确定为肥胖,参考1990年英国人口调查的诊断标准。结果经过最终验证,在假设的25项危险因素中有8项与肥胖有关:父母肥胖(父母双方校正后的相对危险度10.44,95%可信区间5.11~21.32);最早期(43个月内)的体重指数或体重反弹升高(校正后的相对危险度15.00,95%可信区间5.32~42.30);3岁时每周看电视的时间超过8小时(校正后的相对危险度1.55,95%可信区间1.13~2.12);追赶性生长(校正后的相对危险度2.60,95%可信区间1.09~6.16);8个月(校正后的相对危险度3.13,95%可信区间1.43~6.85)和18个月(校正后的相对危险度2.65,95%可信区间1.25~5.59)时体重的标准差值;1岁时体重增加值(校正后的相对危险度1.06,95%可信区间1.02~1.10,体重每增加100g);出生体重,每100g(校正后的相对危险度1.05,95%可信区间1.03~1.07);3岁时睡眠不足(<10.5小时,校正后的相对危险度1.45,95%可信区间1.10~1.89)。结论儿童期肥胖可能与8项危险因素有关。 | John J Reilly Julie Amstrong Ahmad R Dorosty Pauline M Emmett A Ness I Rogers Colin Steer Andrea Sherriff Children Study Team 冯凯 | 2005 | 英国医学杂志中文版2005，8，5： | 8 |
| 2 | 简阳、眉山农村健康保险医疗服务利用及费用分析显示文摘本文旨在分析和研究第一批试点村保险实施后的医疗服务利用,医疗费用的影响因素及变化趋势,为健康保险试点的进一步实施和管理提供依据。一、资料来源 (一) | 何廷尉 普翔凌 Emmett Keele | 1987 | 中国农村卫生事业管理1987，，10： | 7 |
| 3 | LRIF1 interacts with HPla to coordinate accurate chromosome segregation during mitosis显示文摘Heterochromatin protein 1α (HP1α)regulates chromatin specification and plasticity during cell fate decision.Different structural determinants account for HP1α Localization and function during cell division cycle.Our earlier study showed that centromeric Localization of HP1α depends on the epigenetic mark H3K9me3 in interphase,while its centromeric location in mitosis relies on uncharacterized PXVXL-containing factors.Here,we identified a PXVXL-containing protein,Ligand-dependent nuclear receptorinteracting factor 1 (LRIF1),which recruits HPla to the centromere of mitotic chromosomes and its interaction with HP1α is essential for accurate chromosome segregation during mitosis.LRIF1 interacts directly with HPla chromoshadow domain via an evolutionariLy conserved PXVXL motif within its C-terminus.Importantly,the LRIF1-HPla interaction is critical for Aurora B activity in the inner centromere.Mutation of PXVXL motif of LRIF1 Leads to defects in HPla centromere targeting and aberrant chromosome segregation.These findings reveal a previously unrecognized direct Link between LRIF1 and HP1α in centromere plasticity control and illustrate the critical role of LRIF1-HP1α interaction in orchestrating accurate cell division. | Saima Akram Fengrui Yang Junying Li Gregory Adams Yingying Liu Xiaoxuan Zhuang Lingluo Chu Xu Liu Nerimah Emmett Winston Thompson McKay Mullen Saravana Muthusamy Wenwen Wang Fei Mo Xing Liu | 2018 | Journal of Molecular Cell Biology2018，10，6： | 5 |
| 4 | Association between betepost natal catch-up growth and obesity in childhood: prospective co- hort study显示文摘 | Ong KKL Ahmed ML Emmett PM | 2000 | BMJ2000，320，： | 1 |
| 5 | Impact of nitrogen deposition on nitrogen cycling in forest: A synthesis of NITREX data显示文摘 | Gundersen P Emmett B A Kjφnass O J | 1998 | Forest Ecology and Management1998，101，13： | 1 |
| 6 | Adsorption of gases in multimolecular layers显示文摘 | Brunauer S Emmett P H Teller E | 1938 | Journal of American Chemical Society1938，60，2： | 1 |
| 7 | Some mechanism studies on the Fischer-Tropsch synthesis using C14 显示文摘 | Kummer J Dewitt T Emmett P | 1948 | Journal of the American Chemical Society1948，70，11： | 1 |
| 8 | Adsorption of gases in multi- molecular layers显示文摘 | Brunauer S Emmett P H Teller E | 1938 | Journal of the American Chemical Society1938，60，2： | 1 |
| 9 | The Roles of Angiogenesis in Malignant Melanoma: Trends in Basic Science Research over the Last 100 Years显示文摘 | Dewing D Emmett M Pritchard Jones R | 2012 | ISRN Oncol2012，2012，54： | 1 |
| 10 | Fenofibrate attenuates tubulointerstitial fibrosis and inflammation through suppression of nuclear factor-kappaB and transforming growth factor-beta1/Smad3 in diabetic nephropathy显示文摘 | Li L Emmett N Mann D | | 0，，： | 1 |
| 11 | Simple and mixed acid-base disorders:a practical approach (baltimore)显示文摘 | NARINS R G EMMETT M | 1980 | Medicin1980，59，3： | 1 |
| 12 | Angiogenesis andmelanoma - from basic science to clinical trials显示文摘 | Emmett MS Dewing D Pritchard-Jones RO | 2011 | Am J Cancer Res2011，1，7： | 1 |
| 13 | A review and analysis of 11000 fracturesseen in a private practice of orthopaedic surgery, 1937-1956显示文摘 | Emmett JE’Breek LW | 1958 | JBone Joint Surg Am1958，40，5： | 1 |
| 14 | Adsorption of gases in muhimolecular layers 显示文摘 | BRUNAUER B S EMMETT P H TEIJ ER E | 1938 | J Am Chem Soc1938，60，1： | 1 |
| 15 | Adsorption of gases in mul- timolecular layers 显示文摘 | Brunauer S Emmett P H Teller E | 1938 | Journal of the American Chemical So- cienty1938，60，2： | 1 |
| 16 | Chemokine-mediated migration of melanoma cells towards lymphatics--a mechanism contributing to metastasis显示文摘 | Shields JD Emmett MS Dunn DB | 2007 | Oncogene2007，26，21： | 1 |
| 17 | Envelope function:a tool for analyzing flutter data显示文摘 | Cooper J E Emmett P R Wright J R | | 0，，05： | 1 |
| 18 | The closure of defects by using adjacent triangular flaps with subcutaneous pedicles 显示文摘 | Emmett AJ | 1977 | Plast Reconstr Surg1977，59，1： | 1 |
| 19 | Adsorption of gases in multimolecular layers 显示文摘 | Brunaue R S Emmett P H Telle R E | 1938 | Journal of American Chemistry Society1938，60，： | 1 |
| 20 | Chemokine=mediated migration of melanoma cells towards lymphatics-a mechanism contributing to metastasis显示文摘 | ShieldsJD Emmett MS Dunn DB | 2007 | Oncogene2007，26，21： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员