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| 1 | Superior safety of direct oral anticoagulants compared to Warfarin in patients with atrial fibrillation and underlying cancer: a national veterans affairs database study显示文摘Background Studies evaluating safety of warfarin and direct oral anticoagulants(DOACs) for prevention of stroke in patients with atrial fibrillation(AF) are lacking. Methods & Results All patients(n = 196,521) receiving care at veteran’s affairs with active cancer and AF from 2010–2015 were included. One-year mortality was significantly higher in unadjusted analysis with warfarin(44.9%) compared to dabigatran(25%, P < 0.001), rivaroxaban(24.4%, P < 0.001) and apixaban(30%, P < 0.001) and after adjusting for age, sex and type of cancer mortality(OR = 2.66, 95% CI: 2.52–2.82, P < 0.001). Risk of ischemic stroke(13.5% vs. 11.1%, 12.0%, 14.0%) was similar, however risk of hemorrhagic stroke was significantly higher among patients receiving warfarin(1.2%) compared to patients receiving dabigatran(0.5%), rivaroxaban(0.7%) and apixaban(0.8%) respectively, P = 0.04. Conclusions We demonstrated the superior safety profile of DOACs compared to warfarin among patients with underlying cancer and AF. Warfarin was associated with higher mortality, similar ischemic stroke risk but higher risk of hemorrhagic stroke. | Abhishek C Sawant Arnav Kumar Wilmon Mccray Sheldon Tetewsky Linda Parone Srilekha Sridhara Meghana Prakash Hiriyur Prakash Gary Tse Tong LIU Nidhi Kanwar Aishwarya Bhardwaj Sahoor Khan Christopher Manion Ankush Lahoti Ashish Pershad Peter Elkin John Corbelli | 2019 | Journal of Geriatric Cardiology2019，16，9： | 2 |
| 2 | Partition coefficients and their uses显示文摘 | LEO A HANSCHA C ELKINS D | 1971 | Chem Rev1971，71，6： | 1 |
| 3 | Substrate specificity of the RND-type multidrug efflux pumps AcrB and AcrD of Escherichia coli is determined predominantly by two large periplasmic loops显示文摘 | Elkins C A Nikaido H | 2002 | J Bacteriol2002，184，23： | 1 |
| 4 | Methionine requirement of male white Peking ducklings 显示文摘 | ELKIN R G STEWART T S ROGLER J C | 1986 | Poultry Science1986，65，： | 1 |
| 5 | Methionine requirement of male white Peking ducklings显示文摘 | Elkin R G Stewart T S Rogler J C | 1986 | Poultry Sci1986，65，： | 1 |
| 6 | Inhibitor scaffold as new allele specific kinase sub- strates显示文摘 | KRAYBILL B C ELKIN L L BLETHROW J D | 2002 | J Am Chem Soc2002，124，12： | 1 |
| 7 | Subacute osteoporotic compression fracture: misleading magnetic resonance appearance显示文摘 | Frager D Elkin C Swerddlow M | 1998 | Skeletal Radiol1998，17，： | 1 |
| 8 | Efficacy tolerability and quality of life of losartan ,alone or with hydrochloro thiazide Versus amlodpine GIIS in patient with essential hypertension显示文摘 | Elkins M liss C | 1996 | Clin ther1996，18，6： | 1 |
| 9 | CD4^+ T cells mediate lFN-gamma-independent control of Mycobacterium tuberculosis infection both in vitro and in vivo显示文摘 | Cowley S C Elkins K L | 2003 | J Immunol2003，171，9： | 1 |
| 10 | Nitrogen removal in arti- ficial wetlands显示文摘 | Gersberg R M Elkins B V Coldman C R | 1983 | Water Research1983，17，9： | 1 |
| 11 | Recellularization of heart valve graft by a process of adaptive remodeling显示文摘 | Goldstein Sewitt C W | 2001 | Semin Thora Cardiovasc Surg2001，13，41： | 1 |
| 12 | A 26-year experience with surgical management of tetralogy of Fallot:risk analysis for mortality or late reintervention显示文摘 | Knott-Craig C J Elkins RC Lane MM | 1998 | Ann Thorac Surg1998，66，2： | 1 |
| 13 | Development of a serologicl test for Haemophilus ducreyi for seroprevalence studies显示文摘 | Yi K Olsen B | 2000 | J Clin Microbiol2000，38，： | 1 |
| 14 | Electrospinning of linear homopolymers of poly(methyl methacrylate):Exploring relationships between fiber formation,viscosity,molecular weight and concentration in a good solvent显示文摘 | GUPTA P ELKINS C LONG T E | 2005 | Polymer2005，46，13： | 1 |
| 15 | Soil oxygen and tempera- ture effect on tetany potential of three annual forage species 显示文摘 | Elkins C B Hoveland C S | 1977 | Agron J1977，69，： | 1 |
| 16 | Methionine requirement of male white pekin ducklings显示文摘 | Elkin R G Stewart T S Rogler J C | 1986 | Poult Sci1986，65，： | 1 |
| 17 | Characterization of the hgbA locus encoding a Hemoglobin receptor from Haemophilus ducreyi显示文摘 | Elkins C Chen C J Thomas C E | 1995 | Infect Immun1995，63，6： | 1 |
| 18 | Temporary bilateral carotid artery occlusion during surgical exploration of the nasal cavity of the dog显示文摘 | Hedlund C S Tangner C H Elkins A D | 1983 | Vet Surg1983，12，： | 1 |
| 19 | Development of a serological test for Haemophilus ducreyi for seroprevalence studies显示文摘 | Elkins C YI K Olsen B | 2000 | J Clin Microbiol2000，38，4： | 1 |
| 20 | Chimeric analysis of AcrA function reveals the importance of its C-terminal domain in its interaction with the AcrB multidrug efflux pump显示文摘 | Elkins C A Nikaido H | 2003 | J Bacteriol2003，185，： | 1 |
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