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| 1 | Colonoscopic yield of colorectal neoplasia in daily clinical practice显示文摘AIM:To assess the prevalence and location of ad-vanced neoplasia in patients undergoing colonoscopy,and to compare the yield per indication.METHODS:In a multicenter colonoscopy survey (n = 18 hospitals) in the Amsterdam area (Northern Holland),data of all colonoscopies performed during a three month period in 2005 were analyzed. The location and the histological features of all colonic neoplasia were recorded. The prevalence and the distribution ofadvanced colorectal neoplasia and differences in yield between indication clusters were evaluated. Advanced neoplasm was defi ned as adenoma > 10 mm in size,with > 25% villous features or with high-grade dyspla-sia or cancer.RESULTS:A total of 4623 eligible patients underwent a total colonoscopy. The prevalence of advanced neo-plasia was 13%,with 281 (6%) adenocarcinomas and 342 (7%) advanced adenomas. Sixty-seven percent and 33% of advanced neoplasia were located in the distal and proximal colon,respectively. Of all patients with right-sided advanced neoplasia (n = 228),51% had a normal distal colon,whereas 27% had a syn-chronous distal adenoma. Ten percent of all colono-scopies were performed in asymptomatic patients,7% of whom had advanced neoplasia. In the respective procedure indication clusters,the prevalence of right-sided advanced neoplasia ranged from 11%-57%. CONCLUSION:One out of every 7-8 colonoscopies yielded an advanced colorectal neoplasm. Colonoscopy is warranted for the evaluation of both symptomatic and asymptomatic patients. | Jochim S Terhaar sive Droste Mike E Craanen Rene WM van der Hulst Joep F Bartelsman Dick P Bezemer Kim R Cappendijk Gerrit A Meijer Linde M Morsink Pleun Snel Hans ARE Tuynman Roy LJ van Wanrooy Eric IC Wesdorp Chris JJ Mulder | 2009 | World Journal of Gastroenterology2009，15，9： | 6 |
| 2 | Lysosomal dysfunction special to glycogen storage disease type Ⅱ 显示文摘 | Hesselink RP Wagenmakers A J Drost MR | 2003 | Biochem Biophys Acta2003，1637，2： | 1 |
| 3 | Inflammatory lung secretions inhibit dendritic cell maturation and function via neutrophil elastase 显示文摘 | Roghanian A Drost EM Macnee W | 2006 | Am J Respir Crit Care Med2006，174，11： | 1 |
| 4 | F-specific RNA bacteriophages are adequate model organisms for enteric viruses in fresh water显示文摘 | HAVELAAR A H VAN OLPHEN M DROST Y C | 1993 | Appl Environ Microbiol1993，59，： | 1 |
| 5 | Stability and in vitro efficacy of antibiotic-heparin lock solutions potentially useful for treatment of central venous catheter-related sepsis.显示文摘 | Jan C Droste Hassan A Jeraj Alan MacDonald | | 0，，： | 1 |
| 6 | Point dilution methods of investigating groundwater flow by means of radioisotopes 显示文摘 | Drost W Klotz D Koch A | 1968 | Water Resources Research1968，4，1： | 1 |
| 7 | Perceptual characteristics of adductor spasmodic dysphonia显示文摘 | LANGEVELD T P DROST H A FRIJNS J H | 2000 | Ann Otol Rhinol Laryngol2000，109，81： | 1 |
| 8 | Investigation of Detailed Film Cooling Effectiveness and Heat Transfer Distributions on a Gas Turbine Airfoil 显示文摘 | Drost U Bolcs A | 1999 | Journal of Turbomachinery1999，，121： | 1 |
| 9 | Developing Sustainable Tourism for World Heritage Site 显示文摘 | Drost A | 1996 | Annals of tourism research1996，23，2： | 1 |
| 10 | First flush pollution load of urban stormwater runoff显示文摘 | Taebi A Droste R L 2004 | 2004 | Journal of Environmental Engineering2004，3，： | 1 |
| 11 | Microbial activity in aerobic sludge digestion显示文摘 | Droste R L Sanchez W A | 1983 | Water Research1983，17，9： | 1 |
| 12 | Shedding of CD163, a novel regu- latory mechanism for a member of the scavenger receptor cysteine- rich family显示文摘 | Droste A Sorg C Hogger P | 1999 | Biochem Biophys Res Commun1999，256，1： | 1 |
| 13 | Factor-graph algo- rithms for equalization 显示文摘 | DROST R J SINGER A C | 2007 | IEEE Transactions on Signal Processing2007，55，5： | 1 |
| 14 | Efficient estimation in semiparametric GARCH models显示文摘 | Drost F C Klaassen C A J | 1997 | Journal of Econometrics1997，81，1： | 1 |
| 15 | Developing sustainable tourism for World Heritage sites显示文摘 | Drost A Martineau F | 1996 | Annals of Tourism Research1996，23，2： | 1 |
| 16 | Factor-graph algorithms for equaliza- tion显示文摘 | Drost R J Singer A C | 2007 | IEEE Trans Signal Processing2007，55，5： | 1 |
| 17 | Pollution loads in urban runoff and sanitary wastewater显示文摘 | Taebi A Droste R L | | 0，，1： | 1 |
| 18 | Review of Export System (ES), Geagxaphie Information System (GIS), Decision Support System (DSS), and their applications in landfill design and management 显示文摘 | Lukasheh A F Droste R L Warith M A | 2001 | Waste Management Research2001，19，： | 1 |
| 19 | Susceptibility of Brazilian soybean cultivars to Agrobacterium tumefaciens 显示文摘 | Droste A Bodanesc-Zanettini M H Mundstock E | 1994 | Rev Brail Genet1994，17，： | 1 |
| 20 | Developing Sustainable Tourism for World Heritage Sites 显示文摘 | Drost A | 1996 | Annals of Tourism Research1996，23，2： | 1 |
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