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您的检索式：作者名="Douglas L Packer"
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| 1 | Progress in nonpharmcologic therapy of atrial fibrillation 显示文摘 | Douglas L Packer M Sam A | 2003 | J Cardiovasc Electrophysiol2003，14，： | 1 |
| 2 | Reversal of pulmonary vein remodeling after catheter ablation of atrial fibrillation显示文摘BackgroundPulmonary 静脉(PV ) 和正厅经历电、结构在 atrial 纤维性颤动(AF ) 改变。试图决定 PV 和在为 AF 的导管脱离用胸估计了以后,改变的左 atrial (LA ) 颠倒的这研究计算了 .MethodsPV electrophysiologic 学习的断层摄影术(CT ) ,导管脱离在 63 个病人被执行(68% 男性;吝啬的 ±SD 年龄:56 ±10 年) 与征兆的 AF (49% 发作性, 51% 坚持) 。胸 CT 以前被执行并且在导管 ablation.ResultsAt 基线以后的 3 个月,有坚持的 AF 的病人有更大的 LA 体积(91 ±29 厘米 3 对 66 ±27 厘米 3 ;P = 0.003 ) 并且吝啬的 PV ostial 区域(241 ±43 公里 2 对 212 ±47 公里 2 ;P = 0.03 ) 比有发作性的 AF 的病人。在有效倔强的时期和左优异 PV 口的区域之间没有重要关联。在 3 月在脱离以后的后续, 48 个病人(76%) 是在上或离开 antiarrhythmic 药免费的 AF。在 LA 体积有重要减小(77 ±31 厘米 3 到 70 ±28 厘米 3 ;P <0.001 ) 并且吝啬的 PV ostial 区域(224 ±48 公里 2 到 182 ±43 公里 2 ;P <0.001 ) 。有坚持的 AF 的病人在 LA 体积有更多的减小(11.8 ±12.8 厘米 3 对 4.0 ±11.2 厘米 3 ;P = 0.04 ) 并且 PV ostial 区域(62 公里 2 对 34 公里 2 ;P = 0.04 ) 比有发作性的 AF 的那些。平均 PV ostial 区域的减小显著地与 LA 体积的减小被相关(r = 0.38, P = 0.03 ) AF 的 .ConclusionsCatheter 脱离改进 PV ostia 和左中庭的结构的改变。这发现在病人是更明显的,坚持的 AF 由导管脱离对待。 | Jia-Hui WU Hung-Kei LI Daniel M Couri Philip A Araoz Ying-Hsiang Lee Chang-Sheng MA Douglas L Packer Yong-Mei CHA | 2016 | Journal of Geriatric Cardiology2016，13，2： | 0 |
| 3 | Safety and efficacy of balloon angioplasty compared to stent-basedstrategies with pulmonary vein stenosis:A systematic review and meta-analysis显示文摘BACKGROUND Pulmonary vein stenosis(PVS)is an uncommon but known cause of morbidity and mortality in adults and children and can be managed with percutaneous revascularization strategies of pulmonary vein balloon angioplasty(PBA)or pulmonary vein stent implantation(PSI).AIM To study the safety and efficacy outcomes of PBA vs PSI in all patient categories with PVS.METHODS We performed a literature search of all studies comparing outcomes of patients evaluated by PBA vs PSI for PVS.We selected all published studies comparing PBA vs PSI for PVS with reported outcomes of restenosis and procedure-related complications in all patient categories.In adults,PVS following atrial fibrillation ablation and in children PVS related to congenital etiology or post-procedural PVS following total or partial anomalous pulmonary venous return repair were included.The patient-centered outcomes were risk of restenosis requiring re-intervention and procedural-related complications.The metaanalysis was performed by computing odds ratios(ORs)using the random effects model based on underlying statistical heterogeneity.RESULTS Eight observational studies treating 768 severe PVS in 487 patients met our inclusion criteria.The age range of patients was 6 months to 70 years and 67%were males.The primary outcome of the re-stenosis requiring re-intervention occurred in 196 of 325 veins in the PBA group and 111 of 443 veins in the PSI group.Compared to PSI,PBA was associated with a significantly increased risk of re-stenosis(OR 2.91,95%CI:1.15-7.37,P=0.025,I2=79.2%).Secondary outcomes of the procedurerelated complications occurred in 7 of 122 patients in the PBA group and 6 of 69 in the PSI group.There were no statistically significant differences in the safety outcomes between the two groups(OR:0.94,95%CI:0.23-3.76,P=0.929,I^(2)=0.0%).CONCLUSION Across all patient categories with PVS,PSI is associated with reduced risk of re-intervention and is as safe as PBA and should be considered first-line therapy for PVS. | Pradyumna Agasthi Srilekha Sridhara Pattara Rattanawong Nithin Venepally Chieh-Ju Chao Hasan Ashraf Sai Harika Pujari Mohamed Allam Diana Almader-Douglas Yamini Alla Amit Kumar Farouk Mookadam Douglas L Packer David R Holmes Jr Donald J Hagler Floyd David Fortuin Reza Arsanjani | 2023 | World Journal of Cardiology2023，15，2： | 0 |
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