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| 1 | Potential immunomodulation effect of the extract of Nigella sativa on ovalbumin sensitized guinea pigs显示文摘Several different pharmacological effects have been described for Nigella sativa(Siah-Daneh) ,including an anti-inflammatory effect.In the present study,the effect of the extract of N.sativa on lung pathology and blood interleukin-4(IL-4) and interferon-γ(IFN-γ) of sensitized guinea pigs was examined.Three groups(n=8 for each group) of guinea pigs sensitized to ovalbumin(OA) were given drinking water alone,and drinking water containing low and high concentrations of the plant extract,respectively.The animals of the control group(n=8) were treated with saline instead of OA and were given drinking water.The pathological changes of the lung,including infiltration of eosinophils and lymphocytes,local epithelial necrosis,the presence of oedema,thickening of the basement membrane,smooth muscle layer hypertrophy,mucosal secretion,and the presence of mucosal plug,and blood IL-4 and IFN-γof sensi-tized guinea pigs were evaluated.The lungs of the sensitized group showed significant pathological changes(P<0.001) .Blood IL-4 and IFN-γwere increased in sensitized animals compared to the controls(P<0.01 and P<0.001,respectively) .Treatment of sensitized animals with the extract led to a significant decrease in pathological changes of the lung(P<0.01 to P<0.001) ,except for the oedema in the sensitized group treated with low concentration of the extract,but an increased IFN-γ.These results confirm a preventive effect of N.sativa extract on lung inflammation of sensitized guinea pigs. | Mohammad-Hossein BOSKABADY Rana KEYHANMANESH Saeed KHAMENEH Yousef DOOSTDAR Mohammad-Reza KHAKZAD | 2011 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2011，12，3： | 2 |
| 2 | Biofla-vonoids :selective substrates and inhibitors for cyto-chrome P450 CYP1A1 and CYP1B1 显示文摘 | DOOSTDAR H BURKE M D MAYER R T | 2000 | Toxicolo-gy2000，144，1： | 1 |
| 3 | The effects of inducing agents on cytochrome P450 and UDP-glucuronosyl transferase activities in human HepG2 hepatoma cells显示文摘 | Doostdar H Grant MH Melvin WT | 1993 | Biochem Pharmacol1993，46，： | 1 |
| 4 | The effects of inducing agents on cytochrome P450 and UDP-glucuronosyltransferase activities in human Hep G2 hepatoma cells显示文摘 | Doostdar H Grant MH Melvin WT | 1993 | Biochem Pharmacol1993，46，： | 1 |
| 5 | Induction of systemic ac quired resistance in cotton by BTH has a negligible effect on phytophagous insects显示文摘 | Inbar M Doostdar H Gerling D | 2001 | Entomol Exp Appl2001，99，： | 1 |
| 6 | Plant defensive proteins and disease resistance in citrus显示文摘 | Niedz R P Doostdar H Mc-Collum T G | 1995 | Proc Florida State Hort Soc1995，107，： | 1 |
| 7 | A cy- tochrome P450 mediated naringenin 3'-hydroxylase from sweet orange cell cultures显示文摘 | DOOSTDAR H SHAPIRO J P NIEDZ R | 1995 | Plant and Cell Physiology1995，，： | 1 |
| 8 | A hybrid genetic algorithm for the multi-dimensional knapsack problem显示文摘 | F Djannaty S Doostdar | 2008 | Mathematics Sciences2008，3，9： | 1 |
| 9 | Immersion of cucumber fruit in heated water alters chilling-induced physiological changes 显示文摘 | Mccollum T Doostdar H Mayer R | 1995 | Postharvest Biology and Tech- nology1995，6，1： | 1 |
| 10 | Bioflavonoids: selective substrates and inhibitors for cytochrome P450 CYP1A and CYP1B1显示文摘 | Doostdar H Burke M D Mayer R T | 2000 | Toxicology2000，144，： | 1 |
| 11 | Bioflavonoids : selective substrates and inhibitors for cytochrome P450 CYP1A and CYP1 B1 显示文摘 | Doostdar H Burke M D Mayer R T | 2000 | Toxicology2000，144，13： | 1 |
| 12 | 圆锥角膜患者基于角膜曲率验配硬性隐形眼镜的预测公式(英文)显示文摘目的:探讨隐形眼镜基线(BC)和角膜曲率结果(Krf)之间简单的数学相关性。方法:本回顾性研究包括350例400只圆锥角膜的眼睛,其先前五年在学院眼科中心验配硬性隐形眼镜。根据角膜曲率结果患者被分为五组,分别为Krf<7,Krf:7-8,Krf>8,Krf-Krs(两个角膜曲率的差异;平坦和陡峭)=0.3-0.6,Krf-Krs>0.6mm1至5组,使用多元线性回归和蒙罗相关系数推测公式。结果:除了第3组患者,可以在所有组中发现线性相关。第1组,BC=0.211×5.904Krf。第2组,BC=0.456×Krf4.160。第4组,BC=0.321×5.219Krf。第5组,BC=0.337×Krf+5.090。结论:RGP验配新公式的发展,可增强眼科医生工作的信心,避免不必要的和频繁的眼镜试验。通常的隐形眼镜验配方法需要更换新的公式,从而帮助节省时间和费用。 | Mohammad Taher Rajabi Zahra Mohajernezhad-fard Seyede Khojaste Naseri Fahimeh Jafari Askar Doostdar Parviz Zarrinbakhsh Mohammad Bagher Rajabi Sedighen Kohansal | 2011 | 国际眼科杂志2011，11，11： | 1 |
| 13 | The role of plant rapidly induced responses in asymmetric interspecific interactions among insect herbivores 显示文摘 | Inbar M Doostdar H Leibee G L | 1999 | Journal of Chemical Ecology1999，25，8： | 1 |
| 14 | Factors influencing the implementation of a safety management system for construction sites 显示文摘 | Zubaidah Ismail Samad Doostdar Zakaria Hamn | 2012 | Safety Science2012，，3： | 1 |
| 15 | Plant defensive proteins and disease resistance in citrus 显示文摘 | Niedz RP Doostdar H McCollum TG | 1995 | Proceedings of the Florida State Horticultural Society1995，107，： | 1 |
| 16 | Bioflavonoids: selective substrates and inhibitors for cytochrome P450 CYP1A and CYP1B1 显示文摘 | Doostdar H Burke M D Mayer R T | 2000 | Toxicology2000，144，13： | 1 |
| 17 | Design and implementation of SMO for a nonlinear MIMO AHRS 显示文摘 | Doostdar P Keighobadi J | 2012 | Mechanical Systems and Signal Processing2012，32，： | 1 |
| 18 | Design and implementation of SMO for a nonlinear MIMO AHRS显示文摘 | Doostdar P Keighobadi J | 2012 | Mechanical Systems and Sig hal Processing2012，32，10： | 1 |
| 19 | A hybrid genetic algorithm For the multidimensional knapsack problem显示文摘 | Djannaty F Doostdar S | 2008 | International Journal of Contemporary Mathematical Sciences2008，9，3： | 1 |
| 20 | Bioflavonoids: selective substrates and inhibitors for cytoehrome P450 CYP1A and CYP1 B1 显示文摘 | Doostdar H Burke M D Mayer R T | 2000 | Toxicology2000，144，13： | 1 |
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