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    题名 作者 年代 出处 被引量
1Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement显示文摘M Dominici K Le Blanc I Mueller I Slaper-Cortenbach Fc Marini Ds Krause Rj Deans A Keating Dj Prockop Em Horwitz 2006Cytotherapy2006,,4:11
2Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement显示文摘M Dominici K Le Blanc I Mueller I Slaper-Cortenbach Fc Marini Ds Krause Rj Deans A Keating Dj Prockop Em Horwitz 2006Cytotherapy2006,,4:9
3Gastroesophageal reflux disease management according to contemporary international guidelines:A translational study显示文摘AIM:To test the Genval recommendations and the usefulness of a short trial of proton pump inhibitor(PPI) in the initial management and maintenance treatment of gastroesophageal reflux disease(GERD)patients. METHODS:Five hundred and seventy seven patients with heartburn were recruited.After completing a psychometric tool to assess quality of life(PGWBI)and a previously validated GERD symptom questionnaire (QUID),patients were grouped into those with esophagitis(EE,n=306)or without mucosal damage (NERD,n=271)according to endoscopy results. The study started with a 2-wk period of high dose omeprazole(omeprazole test);patients responding to this PPI test entered an acute phase(3 mo)of treatment with any PPI at the standard dose.Finally,those patients with a favorable response to the standard PPI dose were maintained on a half PPI dose for a further 3-mo period. RESULTS:The test was positive in 519(89.9%)patients,with a greater response in EE patients(96.4%) compared with NERD patients(82.6%)(P=0.011). Both the percentage of completely asymptomatic patients,at 3 and 6 mo,and the reduction in heartburn intensity were significantly higher in the EE compared with NERD patients(P<0.01).Finally,the mean PGWBI score was significantly decreased before and increased after therapy in both subgroups when compared with the mean value in a reference Italian population. CONCLUSION:Our study confirms the validity of the Genval guidelines in the management of GERD patients. In addition,we observed that the overall response to PPI therapy is lower in NERD compared to EE patients.Fabio Pace Gabriele Riegler Annalisa de Leone Patrizia Dominici Enzo Grossi the EMERGE Study Group 2011World Journal of Gastroenterology2011,17,9:5
4Helicobacter pylori infection in bleeding peptic ulcer patients after non-steroidal antiinflammatory drug consumption显示文摘AIM:To establish the prevalence of Helicobacter pylori (H. pylori ) infection in patients with a bleeding peptic ulcer after consumption of non-steroidal antiinflamma- tory drugs (NSAIDs). METHODS:A very early upper endoscopy was performed to find the source of upper gastrointestinal bleeding and to take biopsy specimens for analysis of H. pylori infection by the rapid urease (CLO) test, histological examination, and bacterial culture. IgG anti-CagA were also sought. The gold standard for identifying H. pylori infection was positive culture of biopsy specimens or contemporary positivity of the CLO test and the presence of H. pylori on tissue sections. RESULTS:Eighty patients, 61 males (76.3%), mean age 61.2 ± 15.9 years, were consecutively enrolled. Forty-seven (58.8%) patients occasionally consumed NSAIDs, while 33 (41.3%) were on chronic treatment with low-dose aspirin (LD ASA). Forty-four (55.0%) patients were considered infected by H. pylori . The infection rate was not different between patients who occasionally or chronically consumed NSAIDs. The culture of biopsy specimens had a sensitivity of 86.4% and a specificity of 100%; corresponding figures for histological analysis were 65.9% and 77.8%, for the CLO test were 68.2% and 75%, for the combined use of histology and the CLO test were 56.8% and 100%, and for IgG anti-CagA were 90% and 98%. The highest accuracy (92.5%) was obtained with the culture of biopsy specimens.CONCLUSION:Patients with a bleeding peptic ulcer after NSAID/LD ASA consumption frequently have H. pylori infection. Biopsy specimen culture after an early upper gastrointestinal tract endoscopy seems the most efficient test to detect this infection.Francesco Manguso Elisabetta Riccio Germana de Nucci Maria Luisa Aiezza Gerardino Amato Linda Degl'Innocenti Maria Maddalena Piccirillo Gianfranco De Dominicis Tara Santoro Elena Trimarco Antonio Balzano 2011World Journal of Gastroenterology2011,17,40:4
5The local mammalian target of rapamycin(mTOR) modulation:a promising strategy to counteract neurodegeneration显示文摘Alzheimer’s disease (AD) and the evolution of the “Amyloid Hypothesis”: The primary risk factor for dementia is aging, as the overwhelming majority of individuals who have the disease (~95%) are 65 years old or older, and the rate of development of AD doubles roughly every five years from that age, peaking at a nearly 50% population prevalence by the age of 85. The disease is progressive and irreversible, with an average time course of 8 to 10 years. Regardless of catastrophic forecasts for the next decades, its actual prevalence has huge family and social costs.Diego Dolcetta Roberto Dominici 2019Neural Regeneration Research2019,14,10:3
6Clarification of the nomenclature for MSC: The International Society for Cellular Therapy position statement显示文摘EM Horwitz K Le Blanc M Dominici I Mueller I Slaper-Cortenbach FC Marini RJ Deans DS Krause A Keating 2005Cytotherapy2005,,5:2
7Fine particulate air pollution and mortality in 20 U S cities 1987-1994显示文摘Samet JM Dominici F Curriero FC 2000N Engl Med2000,343,24:1
8Glutathione catabolism as a signaling mechanism显示文摘Paolicchi A Dominici S Pieri L 0,,56:1
9Seroprevalence of pestivirus in four species of alpine wildl ungulates in the High Valley of Susaltaly 显示文摘Riekerink O Dominici A Barkema HW 2005Vet Mierobiol2005,,108:1
10Redox modulation of protein kinase/phosphatase balance in melanoma cells: the role of endogenous and gamma - glutamyltransferase - dependent H202 production显示文摘PIERI L DOMINICI S DEL BELLO B 2003Biochim Biophys Acta2003,1621,1:1
11Role of 5-aminolevulinic acid in the diagnosis and treatment of superficial bladder cancer:improvement in diagnostic sensitivity显示文摘De Dominicis C Liberti M Perugia G 2001Urology2001,57,6:1
12On the use of Generalized Additive Models in time-series Studies of air pollution and health显示文摘Dominici F McDermott A Zeger SL 2001Am J Epidermal2001,156,:1
13Analysis of heat genera- tion using ultrasonic vibration for post removal 显示文摘Dominici JT Clark S Scheetz J 2005J Endod2005,31,4:1
14Clarification of the nomenclature for MSC:The International Society for Cellular The- rapy position statement 显示文摘Horwitz EM Le Blanc K Dominici M 2005Cytotherapy2005,7,5:1
15Estimating particulate matter mortality dose response curves and threshold levels : an analysis of daily time series for the 20 largest US cities显示文摘DANIELS M J DOMINICI F SAMET J M 2000Am J Epidemiol2000,152,39:1
16Familial clustering of helcoacter pylori infection:population based study显示文摘DOMINICI P BELLENTANI S BIASE ARD 1999BMJ1999,319,:1
17Seed storage proteins of wild wheat progenitors and their relationships with technological properties 显示文摘CIAFFI M DOMINICI L LAFIANDRA D PORCEDDU E 1992Hereditas1992,116,:1
18Coexpression of messenger RNA for TRK proto-oncogene and low affinity nerve growth factor receptor in neumblastoma with favorable prognosis 显示文摘Konger P Barbany G Dominici C 1993Cancer Res1993,53,9:1
19Time-Series Analysis of Air Pollution and Mortality:A Statistical Review显示文摘Dominici F 2004Health Effects Institute2004,123,:1
20Angiotensin-(1-7) stimulates the phosphorylation of Akt in rat extracardiac tissues in vivo via receptor Mas显示文摘Munoz M C Giani J F Dominici F P 2010Regul Pept2010,161,13:1
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