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6篇 您的检索式:作者名="Dominic SC"
    题名 作者 年代 出处 被引量
1Establishing the presence or absence of chronic kidney disease:Uses and limitations of formulas estimating the glomerular filtration rate显示文摘The development of formulas estimating glomerular filtration rate(eG FR) from serum creatinine and cystatin C and accounting for certain variables affecting the production rate of these biomarkers, including ethnicity, gender and age, has led to the current scheme of diagnosing and staging chronic kidney disease(CKD),which is based on e GFR values and albuminuria.This scheme has been applied extensively in various populations and has led to the current estimates of prevalence of CKD. In addition, this scheme is applied in clinical studies evaluating the risks of CKD and the efficacy of various interventions directed towards improving its course. Disagreements between creatinine-based and cystatin-based e GFR values and between e GFR values and measured GFR have been reported in various cohorts. These disagreements are the consequence of variations in the rate of production and in factors, other than GFR, affecting the rate of removal of creatinine and cystatin C. The disagreements create limitations for all e GFR formulas developed so far. The main limitations are low sensitivity in detecting early CKD in several subjects, e.g., those with hyperfiltration, and poor prediction of the course of CKD. Research efforts in CKD are currently directed towards identification of biomarkers that are better indices of GFR than the current biomarkers and,particularly, biomarkers of early renal tissue injury.Ahmed Alaini Deepak Malhotra Helbert Rondon-Berrios Christos P Argyropoulos Zeid J Khitan Dominic SC Raj Mark Rohrscheib Joseph I Shapiro Antonios H Tzamaloukas 2017World Journal of Methodology2017,7,3:7
2Skeletal muscle,cytokines,and oxidative stress in end-stage renal disease显示文摘Dominic SC Raj Elizabeth A Dominic Amy Pai 2005Kidney International2005,68,:1
3Hemodynamic changs during hemodialysis:Role of nitric oxide and endothelin显示文摘Dominic SC Brad Vincent Keith Simepson 2002Kidney International2002,61,2:1
4Role of Interleukin-6 in the Anemia of Chronic Disease显示文摘Raj Dominic SC 2009Semin Arthritis Rheum2009,38,5:1
5Skeletal muscle, cytokines, and oxidative stress in end-stage renal disease显示文摘Dominic SC Raj Elizabeth A Dominic Amy Pal 2005Kidney International2005,68,:1
6Hemodynamic changs during hemodialysis : Role of nitric oxide and endothelin 显示文摘Dominic SC Brad Vincent Keith Simepson 2002Kidney International2002,61,2:1
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