|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 精神分裂症的社会心理家庭干预显示文摘本文介绍了精神分裂症社会——心理家庭干预的最新研究结果。讨论了干预的作用,不同教育模式的效果,这类多因素治疗方法包含的有效成份以及如何通过这些研究成果加深对这种治疗方法的理解。文章还提出了进一步的研究设想。 | Dominic H Lam 熊卫 | 1991 | 国外医学(精神病学分册)1991，18，4： | 8 |
| 2 | Establishing the presence or absence of chronic kidney disease:Uses and limitations of formulas estimating the glomerular filtration rate显示文摘The development of formulas estimating glomerular filtration rate(eG FR) from serum creatinine and cystatin C and accounting for certain variables affecting the production rate of these biomarkers, including ethnicity, gender and age, has led to the current scheme of diagnosing and staging chronic kidney disease(CKD),which is based on e GFR values and albuminuria.This scheme has been applied extensively in various populations and has led to the current estimates of prevalence of CKD. In addition, this scheme is applied in clinical studies evaluating the risks of CKD and the efficacy of various interventions directed towards improving its course. Disagreements between creatinine-based and cystatin-based e GFR values and between e GFR values and measured GFR have been reported in various cohorts. These disagreements are the consequence of variations in the rate of production and in factors, other than GFR, affecting the rate of removal of creatinine and cystatin C. The disagreements create limitations for all e GFR formulas developed so far. The main limitations are low sensitivity in detecting early CKD in several subjects, e.g., those with hyperfiltration, and poor prediction of the course of CKD. Research efforts in CKD are currently directed towards identification of biomarkers that are better indices of GFR than the current biomarkers and,particularly, biomarkers of early renal tissue injury. | Ahmed Alaini Deepak Malhotra Helbert Rondon-Berrios Christos P Argyropoulos Zeid J Khitan Dominic SC Raj Mark Rohrscheib Joseph I Shapiro Antonios H Tzamaloukas | 2017 | World Journal of Methodology2017，7，3： | 7 |
| 3 | Voxel-based magnetic resonance imaging investigation of poor and preserved clinical insight in people with schizophrenia显示文摘AIM To define regional grey-matter abnormalities in schizophrenia patients with poor insight(Insight-),relative to patients with preserved clinical insight(Insight+),and healthy controls.METHODS Forty stable schizophrenia outpatients(20 Insight-and 20 Insight+) and 20 healthy controls underwent whole brain magnetic resonance imaging(MRI).Insight in all patients was assessed using the Birchwood Insight Scale(BIS;a self-report measure).The two patient groups were preselected to match on most clinical and demographic parameters but,by design,they had markedly distinct BIS scores.Voxel-based morphometry employed in SPM8 was used to examine group differences in grey matter volumes across the whole brain.RESULTS The three participant groups were comparable in age [F(2,57) = 0.34,P = 0.71] and the patient groups did not differ in age at illness onset [t(38) = 0.87,P = 0.39].Insight-and Insight+ patient groups also did not differ in symptoms on the Positive and Negative Syndromes scale(PANSS):Positive symptoms [t(38) = 0.58,P = 0.57],negative symptoms [t(38) = 0.61,P = 0.55],general psychopathology [t(38) = 1.30,P = 0.20] and total PANSS scores [t(38) = 0.21,P = 0.84].The two patient groups,as expected,varied significantly in the level of BIS-assessed insight [t(38) = 12.11,P < 0.001].MRI results revealed lower fronto-temporal,parahippocampal,occipital and cerebellar grey matter volumes in Insightpatients,relative to Insight+ patients and healthy controls(for all clusters,family-wise error corrected P < 0.05).Insight+ patient and healthy controls did not differ significantly(P > 0.20) from each other.CONCLUSION Our findings demonstrate a clear association between poor clinical insight and smaller fronto-temporal,occipital and cerebellar grey matter volumes in stable long-term schizophrenia patients. | Adegboyega Sapara Dominic H Ffytche Michael A Cooke Steven CR Williams Veena Kumari | 2016 | World Journal of Psychiatry2016，6，3： | 3 |
| 4 | Fluid balance concepts in medicine:Principles and practice显示文摘The regulation of body fluid balance is a key concern in health and disease and comprises three concepts. The first concept pertains to the relationship between total body water(TBW) and total effective solute and is expressed in terms of the tonicity of the body fluids. Disturbances in tonicity are the main factor responsible for changes in cell volume, which can critically affect brain cell function and survival. Solutes distributed almost exclusively in the extracellular compartment(mainly sodium salts) and in the intracellular compartment(mainly potassium salts) contribute to tonicity, while solutes distributed in TBW have no effect on tonicity. The second body fluid balance concept relates to the regulation and measurement of abnormalities of sodium salt balance and extracellular volume. Estimation of extracellular volume is more complex and error prone than measurement of TBW. A key function of extracellular volume, which is defined as the effective arterial blood volume(EABV), is to ensure adequate perfusion of cells and organs. Other factors, including cardiac output, total and regional capacity of both arteries and veins, Starling forces in the capillaries, and gravity also affect the EABV. Collectively, these factors interact closely with extracellular volume and some of them undergo substantial changes in certain acute and chronic severe illnesses. Their changes result not only in extracellular volume expansion, but in the need for a larger extracellular volume compared with that of healthy individuals. Assessing extracellular volume in severe illness is challenging because the estimates of this volume by commonly used methods are prone to large errors in many illnesses. In addition, the optimal extracellular volume may vary from illness to illness, is only partially based on volume measurements by traditional methods, and has not been determined for each illness. Further research is needed to determine optimal extracellular volume levels in several illnesses. For these reasons, extracellular volume in severe illness merits a separate third concept of body fluid balance. | Maria-Eleni Roumelioti Robert H Glew Zeid J Khitan Helbert Rondon-Berrios Christos P Argyropoulos Deepak Malhotra Dominic S Raj Emmanuel I Agaba Mark Rohrscheib Glen H Murata Joseph I Shapiro Antonios H Tzamaloukas | 2018 | World Journal of Nephrology2018，7，1： | 3 |
| 5 | Hypertonicity:Clinical entities,manifestations and treatment显示文摘Hypertonicity causes severe clinical manifestations and is associated with mortality and severe short-term and longterm neurological sequelae. The main clinical syndromes of hypertonicity are hypernatremia and hyperglycemia.Hypernatremia results from relative excess of body sodium over body water. Loss of water in excess of intake,gain of sodium salts in excess of losses or a combination of the two are the main mechanisms of hypernatremia.Hypernatremia can be hypervolemic,euvolemic or hypovolemic. The management of hypernatremia addresses both a quantitative replacement of water and,if present,sodium deficit,and correction of the underlying pathophysiologic process that led to hypernatremia.Hypertonicity in hyperglycemia has two components,solute gain secondary to glucose accumulation in the extracellular compartment and water loss through hyperglycemic osmotic diuresis in excess of the losses of sodium and potassium. Differentiating between these two components of hypertonicity has major therapeutic implications because the first component will be reversed simply by normalization of serum glucose concentration while the second component will require hypotonic fluid replacement. An estimate of the magnitude of the relative water deficit secondary to osmotic diuresis is obtained by the corrected sodium concentration,which represents a calculated value of the serum sodium concentration that would result from reduction of the serum glucose concentration to a normal level. | Helbert Rondon-Berrios Christos Argyropoulos Todd S Ing Dominic S Raj Deepak Malhotra Emmanuel I Agaba Mark Rohrscheib Zeid J Khitan Glen H Murata Joseph I Shapiro Antonios H Tzamaloukas | 2017 | World Journal of Nephrology2017，6，1： | 2 |
| 6 | Cognitive therapy for bipolar illness-a pilot study of relapse prevention显示文摘 | Dominic H Bright J Steve J | 2000 | Cognitive Therapy and Research2000，24，5： | 1 |
| 7 | Surprisingly small HONO emissions from snow surfaces at Browning Pass, Antarctica 显示文摘 | Beine H J Amoroso A Domine F | 2006 | Atmos Chem Phys2006，6，： | 1 |
| 8 | Fluxes of nitrates between snow surfaces and the atmosphere in the European high Arctic 显示文摘 | Beine H J Domine F lanniello A | 2003 | Atmos Chem Phys2003，3，： | 1 |
| 9 | Technical basis and proposal for deriving sediment quality criteria for metals显示文摘 | Gerald T A Dominic M D T David J H | 1996 | Environmental Toxicology and Chemistry1996，15，12： | 1 |
| 10 | Flow Batteries for Enhancing Wind Power Integration显示文摘 | DOMINIC D BANHAM H GARETH A | 2012 | IEEE Transaction on Power System2012，27，3： | 1 |
| 11 | Snow-pile and chamber experiments during the Polar Sunrise Experiment 'Alert 2000': exploration of nitrogen chemistry 显示文摘 | Beine H J Domine F Simpson W | 2002 | Atmos Environ2002，36，： | 1 |
| 12 | Strong Growth Forecast in West Africa Subsea Activity显示文摘 | Dominic H | 2002 | Offshore2002，62，2： | 1 |
| 13 | 23 by linkage analysis显示文摘 | Radhakrishna U Blouin JL Mehenni H Mapping one form of autosomal dominant postaxial polydactyly type A to chromosome 7p15-q11 | 1997 | Am J Hum Genet1997，60，3： | 1 |
| 14 | T cell contributions to the different phases of granuloma formation显示文摘 | Dominic O Co Laura H Hogan Shin Il-Kim | 2004 | Immunology Letters2004，，92： | 1 |
| 15 | Native or raw starch digestion: a key step in energy efficient biorefining of grain显示文摘 | George H Robertson Dominic W S Wong Charles C Lee | 2006 | Journal of Agri- cultural and Food Chemistry2006，54，2： | 1 |
| 16 | 100-Mb/s NRZ visible light communications using a post equalized white LED 显示文摘 | H Le Minh D O′Dominic | 2009 | IEEE Photon Technol Lett2009，21，15： | 1 |
| 17 | Genistein inhibitsglutamate-induced apoptotic processes in primary neuronal cellcultures : An involvement of aryl hydrocarbon receptor andestrogen receptor/glycogen synthase kinase-3 (3 intracellularsignaling pathway显示文摘 | Kajta M Domin H Grynkiewicz G | 2007 | Neuroscience2007，145，2： | 1 |
| 18 | Impa- cat of free-falling wedge with water:syn-chronized visual-ization, pressure and acceleration measurement 显示文摘 | Simon G L Dominic A H Stephen R Turnock | 2010 | Fluid Dynamics Research2010，42，3： | 1 |
| 19 | Neuroprotective effects of neuropeptide Y-Y2 and Y5 receptor agonists in vitro and in vivo显示文摘 | Smiaowska M Domin H Ziba B | 2009 | Neuropeptides2009，43，3： | 1 |
| 20 | Genistein inhibits glutamate-induced apoptotic processes in primary neuronal cell cultures : an involvement of aryl hydrocarbon receptor and estrogen receptor/glycogen synthase kinase-3beta intracellular signaling pathway 显示文摘 | Kajta M Domin H Grynkiewicz G | 2007 | Neuroscience2007，145，2： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员