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| 1 | Mesenchymal stem cell therapy in patients with small bowel transplantation:Single center experience显示文摘AIM:To study the effects of mesenchymal stem cell(MSC) therapy on the prevention of acute rejection and graft vs host disease following small bowel transplantation.METHODS: In our transplantation center, 6 isolated intestinal transplants have been performed with MSC therapy since 2009. The primary reasons for transplants were short gut syndrome caused by surgical intestine resection for superior mesenteric artery thrombosis(n = 4), Crohn's disease(n = 1) and intestinal aganglionosis(n = 1). Two of the patients were children. At the time of reperfusion, the first dose of MSCs cultured from the patient's bone marrow was passedinto the transplanted intestinal artery at a dose of 1000000 cells/kg. The second and third doses of MSCs were given directly into the mesenteric artery through the arterial anastomosis using an angiography catheter on day 15 and 30 post-transplant.RESULTS: The median follow-up for these patients was 10.6 mo(min: 2 mo-max: 30 mo). Three of the patients developed severe acute rejection. One of these patients did not respond to bolus steroid therapy. Although the other two patients did respond to antirejection treatment, they developed severe fungal and bacterial infections. All of these patients died in the 2nd and 3rd months post-transplant due to sepsis. The remaining patients who did not have acute rejection had good quality of life with no complications observed during the follow-up period. In addition, their intestinal grafts were functioning properly in the 13th, 25th and 30th month post-transplant. The patients who survived did not encounter any problems related to MSC transplantation.CONCLUSION: Although this is a small case series and not a randomized study, it is our opinion that small bowel transplantation is an effective treatment for intestinal failure, and MSC therapy may help to prevent acute rejection and graft vs host disease following intestinal transplantation. | Sait Murat Do?an Sel?uk K?l?n? Eyüp Kebap?? Cem Tu?men Mustafa ?lmez Cezmi Karaca Alp Gürkan Ma?allah Baran Yusuf Kurtulmu? | 2014 | World Journal of Gastroenterology2014，20，25： | 3 |
| 2 | Epidemiology of upper gastrointestinal symptoms in Brazil(Epi Gastro):A population-based study according to sex and age group显示文摘AIM:To determine the prevalences of symptoms consistent with gastroesophageal reflux disease(GERD)and dyspepsia in South America.METHODS:A telephone survey was conducted among adult owners of land-based telephones in S?o Paulo,Brazil,using previously validated computer-assisted sampling and survey protocols.The Portugueselanguage survey included(1)sociodemographic characteristics(e.g.,weight,height,smoking)and comorbidities;(2)dietary habits;(3)presence of symptoms consistent with GERD or dyspepsia within the prior 3mo;and(4)use of medications and other therapies to manage symptoms.Data were stratified post-hoc into three homogeneous geographical regions of S?o Paulo according to the Social Exclusion Indices of the districts and postal codes.Survey response data from each respondent were weighted by the numbers of adults and landline telephones in each household.The analyses were weighted to account for sampling design and to be representative of the S?o Paulo population according to city census data.RESULTS:Among 4570 households contacted,an adult from 3050(66.7%)agreed to participate.The nonresponse rate was 33.3%.The mean(SE)respondent age was 42.6(16.0)years.More than half of all respondents were women(53.1%),aged 18 through 49 years(66.7%),married or cohabitating(52.5%),and/or above normal-weight standards(i.e.,35.3%overweight and 16.3%obese).A total of 26.5%of women were perimenopausal.More than 20%of respondents reported highly frequent symptoms consistent with GERD(e.g.,gastric burning sensation=20.8%)or dyspepsia(e.g.,abdominal swelling/distension=20.9%)at least once per month.Prevalences of these symptoms were significantly(approximately 1.5-to 2.0-fold)higher among women than men but did not vary significantly as a function of advancing age.For instance,14.1%of women reported that they experienced stomach burning(symptom of GERD)at least twice per week,compared to 8.4%of men(P=0.012 byχ2 test).A total of 15.7%of women reported that they experienced abdominal swelling(symptom of dyspepsia)at least twice per week,compared to 6.4%of men(P<0.001byχ2 test).Despite frequent manifestations of GERD or dyspepsia,most(≥90%)respondents reported that they neither received prescription medications fromphysicians,nor took behavioral measures(e.g.,dietary modifications),to manage symptoms.CONCLUSION:Symptoms consistent with dyspepsia and GERD are prevalent in Brazil and represent major public-health and clinical challenges. | Maria do Rosário Dias de Oliveira Latorre Aline Medeiros da Silva Décio Chinzon Jaime N Eisig Telma RP Dias-Bastos | 2014 | World Journal of Gastroenterology2014，20，46： | 2 |
| 3 | The contourlet transform: an efficient directional multiresolution image representation显示文摘 | Do M N and Vetterli M | 2005 | IEEE Transactions on Image Processing2005，14，12： | 2 |
| 4 | 金龟子绿僵菌分生孢子暴露在B段紫外光下毒力的降低显示文摘The UV-A and UV-B wavelengths of solar radiation may seriously reduce viability of Metarhizium anisopliae conidia,a fungus used extensively in Brazil for insect pest control.The conidial tolerances to UV-A and UV-B radiation were studied for one isolate(IBCB 425) commercially available product produced on rice grains.Aqueous or oil emulsion conidial suspensions were irradiated for 0(control),2,or 3 h using the solar simulator filtered with diacetate filter to remove UV-C radiation which afforded 652 mW·m-2 in the spectral range of 280~370 nm.The UV tolerance was based on conidial germination(viability) and virulence to Diatraea saccharalis larvae.Conidia formulated with oil emulsion had higher survival after 3 h of UV exposure,but the virulence of the conidia previously exposed to 2 h of UV radiation were similar when oil formulated or not.The mortality of D.saccharalis caterpillars exposed to non-UV-irradiated conidia was greater than that of larvae exposed to irradiated conidia,and the LT50 values were lower for the non-irradiated suspensions than for those irradiated.This apparent reduction in virulence was directly related reduction in viability or delay of germination of UV-irradiated conidia. | Edimara A Francisco Drauzio E N Rangel Newton La Scala Jr José C Barbosa Antnia do C B Correia | 2008 | 安徽农业大学学报2008，35，2： | 2 |
| 5 | Chitosan-based femimagnetic membrane显示文摘 | M A Mace^do M N B Silva A R Cestari | 2004 | Physica B2004，，354： | 1 |
| 6 | The contourlet transform : an efficient directional muhireso lution image representation 显示文摘 | DO M N VETFERLI M | 2005 | IEEE Ttans on Image Processing2005，14，12： | 1 |
| 7 | CXC receptor-1 silencing inhibits androgen-independent prostate cancer显示文摘 | Shamaladevi N Lyn DA Escudero DO | 2009 | Cancer Res2009，69，21： | 1 |
| 8 | Wavelet-based Texture Retrieval Using Generalized Gaussian Density and Kullback-Leibler Distance显示文摘 | Do M N Vetterli M | 2002 | IEEE Trans on Image Processing2002，11，2： | 1 |
| 9 | Wavelet-based texture retrieval using generalized gaussian density and kullback-leibler distance显示文摘 | Do M N Martin V M | 2002 | IEEE Transactions on Image Processing (S1057-7149)2002，11，2： | 1 |
| 10 | Compression of power quality event data using 2D representation显示文摘 | Omer N G Do an G E | 2008 | Electric Power Systems Research2008，78，6： | 1 |
| 11 | The nonsubsampled Contourlet transform: theory, design, and applications 显示文摘 | Cunha A L Zhou J Do M N | 2006 | IEEE Transactions on Image Process2006，15，10： | 1 |
| 12 | Directional multiscale mod- eling of images using the contourlet transform显示文摘 | PO D D Y DO M N | 2006 | IEEE Transactions on Image Processing2006，15，6： | 1 |
| 13 | Direetional multiscale modeling of images using the contourlet transform显示文摘 | Ypo D D Do M N | 2006 | IEEE Transactions on Image Proeessing2006，15，6： | 1 |
| 14 | Framing Pyramids 显示文摘 | DO M N VETI'ERLI M | 2003 | IEEE Trans on Signal Processing2003，51，9： | 1 |
| 15 | The contourlet transform:an effi- cient directional multiresolution image representation显示文摘 | Do M N Vetterli M | 2005 | IEEE Transactions on Signal Processing2005，14，12： | 1 |
| 16 | Wavelet-based texture retrieval using generalized Gaussian density and Kullback-Leibler distance显示文摘 | Do M N Vetterli M | 2002 | IEEE Transactions on Image processing2002，11，2： | 1 |
| 17 | Compression of power quality event data using 2D representation显示文摘 | Omer N G Do an G E | 2008 | Electric Power Systems Research2008，78，6： | 1 |
| 18 | Tumor necrosis factor α-induced interleukin-32 is positively regulated via the Syk/protein kinase Cδ/JNK pathway in rheumatoid synovial fibroblasts显示文摘 | Mun S H Kim J W Nah S S Ko N Y Lee J H Kim J D Kim do K Kim H S Choi J D Kim S H Lee C K Park S H Kim B K Kim H S Kim Y M and Choi W S | | 0，，03： | 1 |
| 19 | Antitumor Activity of Cell-Permeable RUNX3 Protein in Gastric Cancer Cells 显示文摘 | Lim J Duong T Do N | 2013 | Clin Cancer Res2013，19，68： | 1 |
| 20 | Physicochemical properties of native and partially gelatinized high-amylose jackfruit (Artocarpus heterophyllus Lain)seed starch显示文摘 | Tran P L Dang H D N Do V H | 2015 | Lebensmittel- Wissenschaft und-Technologie2015，62，2： | 1 |
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