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| 1 | Clinical and cost impact of intravenous proton pump inhibitor use in non-ICU patients显示文摘AIM:To assess the appropriateness of the indication and route of administration of proton-pump-inhibitors (PPIs) and their associated cost impact. METHODS:Data collection was performed prospec-tively during a 6-mo period on 340 patients who re-ceived omeprazole intravenously during their hospital stay in non-intensive care floors. Updated guidelines were used to assess the appropriateness of the indication and route of administration. RESULTS:Complete data collection was available for 286 patients which were used to assess intravenous (IV) PPIs utilization. Around 88% of patients were receiving PPIs for claimed stress ulcer prophylaxis (SUP) indication; of which,only 17% met the guideline criteria for SUP indication,14% met the criteria for non-steroidal-anti-inflammatory drugs-induced ulcer prophylaxis,while the remaining 69% were identifi ed as having an unjustified indication for PPI use. Theinitiation of IV PPIs was appropriate in 55% of pa-tients. Half of these patients were candidates for switching to the oral dosage form during their hos-pitalization,while only 36.7% of these patients were actually switched. The inappropriate initiation of PPIs via the IV route was more likely to take place on the medical floor than the surgical floor (53% vs 36%,P = 0.003). The cost analysis associated with the appro-priateness of the indication for PPI use as well as the route of administration of PPI revealed a possible saving of up to $17 732.5 and $14 571,respectively. CONCLUSION:This study highlights the over-utili-zation of IV PPIs in non-intensive care unit patients. Restriction of IV PPI use for justified indications and route of administration is recommended. | Soumana C Nasser Jeanette G Nassif Hani I Dimassi | 2010 | World Journal of Gastroenterology2010,16,8: | 23 |
| 2 | Stress ulcer prophylaxis guidelines:Are they being implemented in Lebanese health care centers?显示文摘AIM:To evaluate the current practice of stress ulcer prophylaxis (SUP) in Lebanese Health care centers.METHODS:A multi-center prospective chart review study was conducted over 8 mo.A questionnaire was distributed to pharmacy students who collected data on demographics,SUP medications,dose,route,duration and associated risk factors.The appropriateness of SUP use was determined as per American Society of Health-System Pharmacists guidelines.Institutional review board approval was obtained from each hospital center.RESULTS:A total of 1004 patients were included.67% of the patients who received prophylaxis did not have an indication for SUP.The majority (71.6%) of the patients who were administered parenteral drugs can tolerate oral medications.Overall,the regimen of acid-suppressant drugs was suboptimal in 87.6% of the sample.This misuse was mainly observed in non-teaching hospitals.CONCLUSION:This study highlighted the need,in Lebanese hospitals,to establish clinical practice guidelines for the use of SUP;mainly in non-critical care settings. | Abeer Zeitoun Maya Zeineddine Hani Dimassi | 2011 | World Journal of Gastrointestinal Pharmacology and Therapeutics2011,2,4: | 10 |
| 3 | Predictors and outcomes of patient safety culture in hospitals显示文摘 | El-Jardali F Dimassi H Jamal D | 2011 | BMC Health Serv Res2011,11,1: | 1 |
| 4 | Nutritional status, growth, CO2 assimilation and leaf anatomical responses in two kiwifruit species under boron toxicity显示文摘 | Sotiropoulos T E Therios I N Dimassi K N | 2002 | Journal of Plant Nutrition2002,25,6: | 1 |
| 5 | Oxidative stress, antioxidant activity and Fe(III)-chelate reductase activity of five Prunus rootstocks explants in response to Fe deficiency显示文摘 | Athanassios N. Molassiotis Grigorios C. Diamantidis Ioannis N. Therios Vassilios Tsirakoglou Kortessa N. Dimassi | 2005 | Plant Growth Regulation2005,,1: | 1 |
| 6 | Porous silicon-based passivation and getting in polycrystalline silicon solar cells 显示文摘 | Dimassi W Bouaicha M Saadoun M | 2003 | Nuclear Instruments and Methods in Physics Research2003,186,: | 1 |
| 7 | Ultrasonographic Diagnostic Criterion for Severe Diaphragmatic Dysfunction After Cardiac Surgery显示文摘 | Nicolas Lerolle Emmanuel Guérot Saoussen Dimassi Rachid Zegdi Christophe Faisy Jean-Yves Fagon Jean-Luc Diehl | 2009 | Chest2009,,: | 1 |
| 8 | Effects of nor-epinephrine on static and dynamic preload indicators inexperimental hemorrhagic shock 显示文摘 | Nouira S Elatrous S Dimassi S | 2005 | Crit Care Med2005,33,10: | 1 |
| 9 | Evaluation of the diffusion length of gettered muhicrystalline silicon using solar cells - cross - sectional LBIC scan 显示文摘 | Bouaicha M Dimassi W Nouri H | 2005 | Physica Status Solidi ( a)2005,202,: | 1 |
| 10 | Evaluating the degree of difficulty of laparoscopic colorectal surgery 显示文摘 | Jamali FR Soweid AM Dimassi H | 2008 | Arch Surg2008,143,8: | 1 |
| 11 | Evaluating the degree of difficulty of laparoscopic colorectal surgery显示文摘 | Jamali FR Soweid AM Dimassi H | 2008 | Arch Surg2008,143,8: | 1 |
| 12 | A national cross- sectional study on nurses' intent to leave and job satisfaction in Lebanon:implications for policy and practice显示文摘 | EI-Jardali F Dimassi H Dumit N | 2009 | BMC Nurs- ing2009,8,3: | 1 |
| 13 | Evaluating the degree of difficulty of laparoscopic colorectal surgery 显示文摘 | Jamali FR Soweid AM Dimassi H | 2008 | Arch Surg2008,143,8: | 1 |
| 14 | Evaluating the degree of difficulty of laparoscopic colorectal surgery 显示文摘 | Jamali FR Soweid AM Dimassi H | 2008 | Arch Surg2008,143,8: | 1 |
| 15 | Effects of B Excess on Some Physiological and Anatomical Parameters of Navelina Orange Plants Grafted on Two Rootstocks显示文摘 | PAPADAKIS I E DIMASSI KN BOSABALIDIS A M | 2004 | Enviromental and Experimental Botany2004,51,: | 1 |
| 16 | The current state of patient safety culture in Lebanese hospitals= a study at baseline显示文摘 | E1 Jardali F Jaafar M Dimassi H | 2010 | Int J Qual Health Care2010,22,38: | 1 |
| 17 | Response of two citrus genotypes to six boron concentrations:concentration and distribution of nutrients, total absorption, and nutrient use effi- cieney显示文摘 | PAPADAKIS I DIMASSI K THERIOS I | 2003 | Australian Journal of Agricultural Research2003,54,6: | 1 |
| 18 | The influence of radiation quality on the in vitro rooting and nutrient concentrations of peach rootstock显示文摘 | ANTONOPOULOU C DIMASSI K THERIOS I CHATZISSAV- VIDIS C | 2004 | Biologia Planta- rum2004,48,4: | 1 |
| 19 | lmnong of gestafional trophoblastic disease 显示文摘 | Chelli D Dimassi K Bouaziz M | 2008 | J Gynecol Obstet Biol Reprod (Paris)2008,37,6: | 1 |
| 20 | Early diagnosis and management of cervical ectopic pregnancy 显示文摘 | Chelli D Dimassi K Bouaziz M | 2009 | Tunis Med2009,87,9: | 1 |