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310篇 您的检索式:作者名="Dhalla"
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1Bacterial presence on flexible endoscopes vs time since disinfection显示文摘AIM To correlate the length of endoscope hang time and number of bacteria cultured prior to use.METHODS Prospectively, we cultured specimens from 19 gastroscopes, 24 colonoscopes and 5 side viewing duodenoscopes during the period of 2011 to 2015. A total of 164 results had complete data denoting date of cleansing, number of days stored and culture results. All scopes underwent initial cleaning in the endoscopy suite utilizing tap water, and then manually cleaned and flushed. High level disinfection was achieved with a Medivator~? DSD(Medivator Inc., United States) automated endoscope reprocessor following manufacturer instructions, with Glutacide~?(Pharmax Limited, Canada), a 2% glutaraldehyde solution. After disinfection, all scopes were stored in dust free, unfiltered commercial cabinets for up to 7 d. Prior to use, all scopes were sampled and plated on sheep blood agar for 48 h; the colony count was obtained from each plate. The length of endoscope hang time and bacterial load was analyzed utilizing unpaired t-tests. The overall percentage of positive and negative cultures for each type of endoscope was also calculated. RESULTS All culture results were within the acceptable range(less than 200 cfu/mL). One colonoscope cultured 80 cfu/mL after hanging for 1 d, which was the highest count. ERCP scopes cultured at most 10 cfu, this occurred after 2 and 7 d, and gastroscopes cultured 50 cfu/mL at most, at 1 d. Most cultures were negative for growth, irrespective of the length of hang time. Furthermore, all scopes, with the exception of one colonoscope which had two positive cultures(each of 10 cfu/mL), had at most one positive culture. There was no significant difference in the number of bacteria cultured after 1 d compared to 7 d when all scopes were combined(day 2: P = 0.515; day 3: P = identical; day 4: P = 0.071; day 5: P = 0.470; day 6: P = 0.584; day 7: P = 0.575). There was also no significant difference in the number of bacteria cultured after 1 day compared to 7 d for gastroscopes(day 2: P = 0.895; day 3: P = identical; day 4: P = identical; day 5: P = 0.893; day 6: P = identical; day 7: P = 0.756), colonoscopes(day 2: P = 0.489; day 4: P = 0.493; day 5: P = 0.324; day 6: P = 0.526; day 7: P = identical), or ERCP scopes(day 2: P = identical; day 7: P = 0.685). CONCLUSION There is no correlation between hang time and bacterial load. Endoscopes do not need to be reprocessed if reused within a period of 7 d.Katlin I Mallette Peter Pieroni Sonny S Dhalla 2018World Journal of Gastrointestinal Endoscopy2018,10,1:3
2Role of oxidative stress in cardiovascular diseases显示文摘Naranjan S. Dhalla Rana M. Temsah Thomas Netticadan 2000Journal of Hypertension2000,,6:2
3Alterations in heart sarcolemmal Ca2+-ATPase and Ca2+-binding activities due to oxygen free radicals显示文摘M. Kaneko P. K. Singal Dr. N. S. Dhalla 1990Basic Research in Cardiology1990,,1:2
4Status of myocardial antioxidants in ischemia-reperfusion injury显示文摘Dhalla N S Elmoselhi A B Hata T 2000Cardiovasc Res2000,47,3:1
5Ischemia-reperfusion induced changes in sarcolemmal Na^+/K^+-ATPase are due to the activation of calpain in the heart显示文摘Singh RB Dhalla NS 2010Can J Physiol Pharmacol2010,88,3:1
6Role of oxidative stress in cardiovascular diseases显示文摘Dhalla NS Temsah RM Netticadan T 2000J Hypertens2000,18,6:1
7Subcellular remodelling may induce cardiac dysfunction in congestive heart failure显示文摘Dhalla NS Saini-Chohan HK Rodriguez-Leyva D Cardiovascular Research0,,:1
8Angiogenesis-a new target for future therapy显示文摘Pandya NM Dhalla NS Santani DD 2006Vascul Phamacol2006,44,5:1
9Partial prevention of changes in SR gene expression in congestive heart failure due to myocardial infarction by enalapril or losartan显示文摘Guo X Chapman D Dhalla NS 2003Mol Cell Biochem2003,254,12:1
10Role of H202 in changing beta-adrenoceptor and adenylyl cyclase in ischmia-reperfused hearts显示文摘 Dhalla NS 1998Mol Cell Biochem1998,186,:1
11Subcellular remodeling as a viable target for the treatment of congestive heart failure显示文摘Dhalla NS Dent MR Tappia PS 2006J Cardiovasc Pharmacol Therapeut2006,11,1:1
12Modification of beta adrenoceptor signal transduction pathway by genetic manipulation and heart failure显示文摘WANG X DHALLA N S 2000Mol Cell Biochem2000,214,12:1
13Angiogenesis-a new target for future therapy 显示文摘Pandya NM Dhalla NS Santani DD 2006Vascul Pharmacol2006,44,5:1
14Retinal pigment epithelial tear following intravitreal pegaptanib sodium 显示文摘Dhalla MS Blinder K J Tewari A 2006Am J Ophthalmol2006,142,4:1
15Development of cardiac sensitivity to oxygen deficiency: comparative and ontogenetic aspects 显示文摘Ostadal B Ostadalova I Dhalla NS 1999physiol Rev1999,79,3:1
16Role of oxidative stress in transition of hypertrophy to heart failure显示文摘 Hill MF Singal PK 1996J Am Coll Cardiol1996,28,2:1
17Role of oxidative stress in alterations of mitochondrial function in ischemic-reperfused hearts显示文摘Makazan Z Saini H K Dhalla N S 2007Am J Physiol Heart Circ Physiol2007,292,:1
18Blood flow velocity quantification using split-spectrum amplitude decorrelation angiography with optical coherence tomography 显示文摘Tokayer J Jia Y Dhalla AH 2013Biomed Opt Express2013,4,10:1
19Subcellular remodelling may induce cardiac dysfunctionin congestive heart failure显示文摘Dhalla N S Saini-Chohan H K Rodriguez-Leyva D 2009Cardiovasc Res2009,81,3:1
20Potential of endothelin-1 and vasopressin antagonists for the treatment of congestive heart failure显示文摘Rehsia NS Dhalla N 2010Heart Fail Rev2010,15,1:1
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