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2篇 您的检索式:作者名="Devdas Pai"
    题名 作者 年代 出处 被引量
1Magnesium incorporated chitosan based scaffolds for tissue engineering applications显示文摘Chitosan based porous scaffolds are of great interest in biomedical applications especially in tissue engineering because of their excellent biocompatibility in vivo,controllable degradation rate and tailorable mechanical properties.This paper presents a study of the fabrication and characterization of bioactive scaffolds made of chitosan(CS),carboxymethyl chitosan(CMC)and magnesium gluconate(MgG).Scaffolds were fabricated by subsequent freezing-induced phase separation and lyophilization of polyelectrolyte complexes of CS,CMC and MgG.The scaffolds possess uniform porosity with highly interconnected pores of 50-250 μm size range.Compressive strengths up to 400 kPa,and elastic moduli up to 5 MPa were obtained.The scaffolds were found to remain intact,retaining their original threedimensional frameworks while testing in in-vitro conditions.These scaffolds exhibited no cytotoxicity to 3T3 fibroblast and osteoblast cells.These observations demonstrate the efficacy of this new approach to preparing scaffold materials suitable for tissue engineering applications.Udhab Adhikari Nava PRijal Shalil Khanal Devdas Pai Jagannathan Sankar Narayan Bhattarai 2016Bioactive Materials2016,1,2:2
2Corrosion Behavior of Reactive Sputtered Al_2O_3 and ZrO_2 Thin Films on Mg Disk Immersed in Saline Solution显示文摘Magnesium has attracted a lot of attention over the last few decades due to its light weight and potential use as biomaterial. However, the poor corrosion resistance of magnesium restricts its practical use for application where exposure to aggressive aqueous media is unavoidable. This paper describes the growth,characterization and corrosion analyses of Al2O3 and ZrO2 thin film coatings aimed at slowing down the fast degradation of Mg in saline solution. In this study, different thicknesses of Al2O3 and ZrO2 were deposited on pure magnesium(99.95%) disk using pulsed-DC reactive sputtering process. The microstructure and phase analyses were performed using scanning electron microscopy(SEM) and X-ray diffraction(XRD),respectively. The corrosion protection behavior of the Al2O3 and ZrO2 coated magnesium samples immersed in 0.9 wt% NaC l solution were evaluated using electrochemical measurement techniques, such as open-circuit potential(OCP), potentiodynamic polarization(PD) and electrochemical impedance spectroscopy(EIS). The microstructural analyses showed that the Al2O3 thin film coatings have circular grains between5 and 25 nm, while the ZrO2 coatings have bigger ellipsoidal grains. The results from the electrochemical corrosion analyses showed that the Al2O3 coated Mg disk had corrosion resistance of approximately 3 times that of ZrO2 coated Mg disk. It was also observed that increasing the thickness of the Al2O3 coating improved the corrosion resistance of the Mg disk. These results suggest that Al2O3 and ZrO2 coating can be used to effectively control the fast degradation of magnesium for medical implant applications.Ruben Kotoka Sergey Yarmolenko Devdas Pai Jag Sankar 2015Journal of Materials Science & Technology2015,31,9:1
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