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| 1 | Sensory innervation around immediately vs. delayed loaded implants: a pilot study显示文摘Although neurophysiological and psychophysical proof of osseoperception is accumulating, histomorphometric evidence for the neural mechanisms of functional compensation following immediate and delayed implant loading is still lacking. For this randomized split-mouth study, six mongrel dogs randomly received one of four treatment protocols at 36 implant-recipient sites over 16 weeks(third maxillary incisor, third and fourth mandibular premolar): immediate implant placement and immediate loading(IIP1IL);delayed implant placement and delayed loading(DIP1DL); delayed implant placement and immediate loading(DIP1IL); and natural extraction socket healing(control). Histomorphometry was performed in the peri-implant bone and soft tissues within 300 mm around the implants. Immunocytochemistry and transmission electron microscopy were used to confirm the presence of neural structures and to reveal their ultrastructural characteristics, respectively. Myelinated nerve fibres densely populated the peri-implant crestal gingival and apical regions, although they were also identified in the woven bone and in the osteons near the implant threads. Compared with the control group in the mandible, the group that received IIP1 IL showed a higher innervation(in Nmm22, 5.9461.12 vs. 3.1560.63,P,0.001) and smaller fibre diameter(in mm, 1.3760.05 vs. 1.6460.13, P50.016), smaller axon diameter(in mm, 0.8960.05 vs.1.2460.10, P50.009) and g-ratio(0.6460.04 vs. 0.7660.05, P,0.001) in the middle region around the implants. Compared with DIP1 IL in the mandible, IIP1 IL had a higher nerve density(in Nmm22, 13.2362.54 vs. 9.6461.86, P50.027), greater fibre diameter(in mm, 1.3260.02 vs. 1.2060.04, P50.021), greater axon diameter(in mm, 0.9260.01 vs. 0.8960.03, P50.035) and lower g-ratio(0.6960.01 vs. 0.7460.01, P50.033) in the apical region around the implants. It may be assumed that the treatment protocol with IIP1 IL is the preferred method to allow optimized peri-implant re-innervation, but further functional measurements are still required. | Yan Huang Jeroen van Dessel Wendy Martens Ivo Lambrichts Wei-Jian Zhong Guo-Wu Ma Dan Lin Xin Liang Reinhilde Jacobs | 2015 | International Journal of Oral Science2015，7，1： | 7 |
| 2 | Validation of a novel imaging approach using multi-slice CT and cone-beam CT to follow-up on condylar remodeling after bimaxillary surgery显示文摘The main goal of this study was to introduce a novel three-dimensional procedure to objectively quantify both inner and outer condylar remodelling on preoperative multi-slice computed tomography(MSCT) and postoperative cone-beam computed tomography(CBCT) images. Second, the reliability and accuracy of this condylar volume quantification method was assessed. The mandibles of 20 patients(11 female and 9 male) who underwent bimaxillary surgery were semi-automatically extracted from MSCT/CBCT scans and rendered in 3D. The resulting condyles were spatially matched by using an anatomical landmark-based registration procedure.A standardized sphere was created around each condyle, and the condylar bone volume within this selected region of interest was automatically calculated. To investigate the reproducibility of the method, inter-and intra-observer reliability was calculated for assessments made by two experienced radiologists twice five months apart in a set of ten randomly selected patients. To test the accuracy of the bone segmentation, the inner and outer bone structures of one dry mandible, scanned according to the clinical set-up, were compared with the gold standard, micro-CT. Thirty-eight condyles showed a significant(P<0.05) mean bone volume decrease of 26.4% ± 11.4%(502.9 mm^3± 268.1 mm^3). No significant effects of side, sex or age were found. Good to excellent(ICC>0.6) intra-and inter-observer reliability was observed for both MSCT and CBCT. Moreover, the bone segmentation accuracy was less than one voxel(0.4 mm) for MSCT(0.3 mm ± 0.2 mm) and CBCT(0.4 mm ± 0.3 mm), thus indicating the clinical potential of this method for objective follow-up in pathological condylar resorption. | laura ferreira pinheiro nicolielo jeroen van dessel eman shaheen carolina letelier marina codari constantinus politis ivo lambrichts reinhilde jacobs | 2017 | International Journal of Oral Science2017，9，3： | 7 |
| 3 | Validating cone-beam computed tomography for peri-implant bone morphometric analysis显示文摘Cone-beam computed tomography(CBCT) has been recently used to analyse trabecular bone structure around dental implants. To validate the use of CBCT for three-dimensional(3D) peri-implant trabecular bone morphometry by comparing it to two-dimensional(2D) histology, 36 alveolar bone samples(with implants n527 vs. without implants n59) from six mongrel dogs, were scanned ex vivo using a high-resolution(80 mm)CBCT. After scanning, all samples were decalcified and then sectioned into thin histological sections(,6 mm)to obtain high contrast 2D images. By using CTAn imaging software, bone morphometric parameters including trabecular number(Tb.N), thickness(Tb.Th), separation(Tb.Sp) and bone volume fraction(BV/TV) were examined on both CBCT and corresponding histological images. Higher Tb.Th and Tb.Sp, lower BV/TV and Tb.N were found on CBCT images(P,0.001). Both measurements on the peri-implant trabecular bone structure showed moderate to high correlation(r50.65–0.85). The Bland–Altman plots showed strongest agreement for Tb.Th followed by Tb.Sp, Tb.N and BV/TV, regardless of the presence of implants. The current findings support the assumption that peri-implant trabecular bone structures based on high-resolution CBCT measurements are representative for the underlying histological bone characteristics, indicating a potential clinical diagnostic use of CBCT-based peri-implant bone morphometric characterisation. | Yan Huang Jeroen Van Dessel Maarten Depypere Mostafa EzEldeen Alexandru Andrei Iliescu Emanuela Dos Santos Ivo Lambrichts Xin Liang Reinhilde Jacobs | 2014 | Bone Research2014，2，2： | 3 |
| 4 | Roux-en-Y gastric bypass as a re-do procedure for failed restrictive gastric surgery 显示文摘 | Van Dessel E Hubens G Ruppert M | 2008 | Surg Endosc2008，22，： | 1 |
| 5 | 显示文摘 | Thierry van Dessel H J Lee PD Faessen G | 1999 | J Clin Endocrinol Metab1999，84，9： | 1 |
| 6 | The value of medical history taking as risk indicator for tuboperitoneal pathology: a systematic review 显示文摘 | LUTFJEBOER F Y VERHOEEVE H R VAN DESSEL H J | 2008 | Infect Dis Clin North Am2008，22，4： | 1 |
| 7 | Job turnover intention among pharmacy faculty显示文摘 | Conklin MH Desselle SP | 2007 | AmJ Pharm Educ2007，71，4： | 1 |
| 8 | Early detection of microcircu-latory impairment in diabetic patients with foot at risk显示文摘 | ZIMNY S DESSEL F EHREN M | 2001 | DiabetesCare2001，24，10： | 1 |
| 9 | Early detection of microcirculatory impairment in diabetic patients with foot at risk显示文摘 | Zimny S Dessel F Ehren M | | 0，，： | 1 |
| 10 | Serum and follicular fluid levels of insulin-like growth factor I (IGF- I ), IGF-Ⅱ, and IGF-binding protein-1 and -3 during the normal menstrual cycle显示文摘 | Thierry van Dessel H J Chandrasekher Y Yap OW | 1996 | J Chn Endocrinol Metab1996，81，3： | 1 |
| 11 | Early detection of microcirlatory impairment in diabetic patients with foot at risk显示文摘 | Zimny S Dessel F Ehren M | 2001 | Diabetes Care2001，24，10： | 1 |
| 12 | Elevated serum levels of free insulin-like growth factor - 1 in polycystic ovary syndrome 显示文摘 | Dessel THJ Lee PD Faessen G | 1999 | J Clin Endocrinol Metab1999，84，9： | 1 |
| 13 | Early detection of microeireu- latory impairment in diabetic patientswith foot at risk显示文摘 | Zimny S Dessel F Ehren M | 2001 | Diabe- tes Care2001，24，10： | 1 |
| 14 | Gonadotrophin induction of ovulation using a step-down dose regimen: single-centre clin- ical experience in 82 patients显示文摘 | van Santbrink E J Donderwinkel PF van Dessel TJ | 1995 | Hum Reprod1995，10，5： | 1 |
| 15 | Active thermal insulators:Finite elements modeling and parametric study of thermoelectric modules integrated into a double pane glazing system显示文摘 | Dessel S V Foubert B | | 0，，7： | 1 |
| 16 | Outbreak of a susceptible strain of Acinetobacter species 13 ( sensu Tjemberg and Ursing) in an adult neurosurgical intensive care unit显示文摘 | van Dessel H Kamp-Hopmans TE Fluit AC | 2002 | J Hosp Infect2002，51，2： | 1 |
| 17 | Elevated serum levels of free insulin-like growth factor I in polycystic ovary syndrome 显示文摘 | Thierry van Dessel HI Lee PD Fanssen G Fauser BC Giudice LC | 2009 | J Clin Endocrinol Metab2009，84，9： | 1 |
| 18 | Feasibility and Optimization of Rigidified Inflatable Structures for Housing显示文摘 | VAN DESSEL S MESSAC A MULLUR A A | 2003 | JOURNAL OF STRUCTUR- AL ENGINEERING2003，129，11： | 1 |
| 19 | Efficacy and safety of percutaneous treatment of iatrogenic femoral artery pseudoaneurysm by biodegradable collagen injection显示文摘 | Hamraoui K Ernst Dessel | 2002 | J Am Coll Cardiol2002，39，8： | 1 |
| 20 | Effects of immedi- ate and delayed loadings on peri- implant trabecular struc tures : a cone beam CT evaluation 显示文摘 | Huang Y Van Dessel J Liang X | 2013 | Clin Implant Dent Re- lat Res2013，2，： | 1 |
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