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| 1 | Early epileptic seizures after stroke are associated with increased risk of newonset dementia 显示文摘 | Cordonnier C Henon H Derambure P | 2007 | Neurol Neurosurg Psychiat2007，78，5： | 1 |
| 2 | Sleep disorders in aging and dementia 显示文摘 | Bombois S Derambure P Pasquier F | 2010 | J Nutr Health Aging2010，14，3： | 1 |
| 3 | Influence of pre?existing dementia on the risk of post-stroke epileptic seizures显示文摘 | Cordonnier C Henon H Derambure P | 2005 | J Neurol Neurosurg Psychiatry2005，76，12： | 1 |
| 4 | Early epileptic seizures after stroke are associated with increased risk of new-on?set dementia显示文摘 | Cordonnier C Henon H Derambure P | 2007 | J Neurol Neurosurg Psychiatry2007，78，5： | 1 |
| 5 | Early epileptic seizures after stroke areassociatedwith increased risk of newonset dementia显示文摘 | Cordonnier C Henon H Derambure P | 2007 | J Neurol Neurosurg Psychiatry2007，78，5： | 1 |
| 6 | Sleep disorders in aging and dementia 显示文摘 | Bombois S Derambure P Pasquier F | 2010 | The J Nutr Health Aging2010，14，： | 1 |
| 7 | Early epileptic seizures fter stroke are associated with increased risk of new-onset dementia显示文摘 | Cordonnier C Henon H Derambure P | 2007 | Neural Neurosurg Psychiatry2007，78，5： | 1 |
| 8 | Genome-wide differences in hepatitis C-vs alcoholism-associated hepatocellular carcinoma显示文摘AIM:To look at a comprehensive picture of etiology- dependent gene abnormalities in hepatocellular carcinoma in Western Europe. METHODS:With a liver-oriented microarray,transcript levels were compared in nodules and cirrhosis from a training set of patients with hepatocellular carcinoma (alcoholism,12;hepatitis C,10)and 5 controls.Loose or tight selection of informative transcripts with an abnormal abundance was statistically valid and the tightly selected transcripts were next quantified by qRTPCR in the nodules from our training set(12+10) and a test set(6+7). RESULTS:A selection of 475 transcripts pointed to significant gene over-representation on chromosome 8 (alcoholism)or-2(hepatitis C)and ontology indicated a predominant inflammatory response(alcoholism)or changes in cell cycle regulation,transcription factors and interferon responsiveness(hepatitis C).A stringent selection of 23 transcripts whose differences betweenetiologies were significant in nodules but not in cirrhotic tissue indicated that the above dysregulations take place in tumor but not in the surrounding cirrhosis.These 23 transcripts separated our test set according to etiologies. The inflammation-associated transcripts pointed to limited alterations of free iron metabolism in alcoholic vs hepatitis C tumors. CONCLUSION:Etiology-specific abnormalities(chromo- some preference;differences in transcriptomes and related functions)have been identified in hepatocellular carcinoma driven by alcoholism or hepatitis C.This may open novel avenues for differential therapies in this disease. | Céline Derambure Cédric Coulouarn Frédérique Caillot Romain Daveau Martine Hiron Michel Scotte Arnaud Franois Celia Duclos Odile Goria Marie Gueudin Catherine Cavard Benoit Terris Maryvonne Daveau Jean-Philippe Salier | 2008 | World Journal of Gastroenterology2008，14，11： | 1 |
| 9 | Gene profiling pre-dicts rheumatoid arthritis responsiveness toIL-1 Ra(anakinra) 显示文摘 | Bansard C Lequerre T Derambure C | 2011 | Rheumatology( Oxford)2011，50，2： | 1 |
| 10 | Gene profiling predicts rheumatoid arthritis responsiveness to IL-1 Ra (anakinra)显示文摘 | Bansard C Lequerre T Derambure C | | 0，，： | 1 |
| 11 | Outer retinal dysfunction in patients treated with vigabatrin显示文摘 | Arndt CF Derambure P Defoort-Dhellemmes S | 1999 | Neurology1999，52，： | 1 |
| 12 | Sleep Disorders in Aging and Dementia显示文摘 | Bombois S Derambure P Pasquier F | 2010 | J Nutr Health Aging2010，14，3： | 1 |
| 13 | Management of restless legs and periodic movement of sleep显示文摘 | MONACA C DERAMBURE P | 2004 | Rev Neurol (Paris)2004，160，67： | 1 |
| 14 | Transient and etiology-related transcription regulation in cirrhosis prior to hepatocellular carcinoma occurrence显示文摘AIM:To search for transcription dysregulation that could(1) differentiate hepatocellular carcinoma(HCC)-free from HCC-related cirrhosis(2) differentiate HCC-free cirrhosis related to HCV from that related to alcohol intake.METHODS:Using microarray analysis,we compared transcript levels in HCC-free cirrhosis(alcoholism:7;hepatitis C:7),HCC-associated cirrhosis(alcoholism:10;hepatitis C:10) and eight control livers.The identified transcripts were validated by qRT-PCR in an independent cohort of 45 samples(20 HCC-free cirrhosis;15 HCC-associated cirrhosis and 10 control livers).We also confirmed our results by immunohistochemistry.transcripts which differentiated between alcoholic-related cirrhosis,HCV-related cirrhosis and control livers.They mainly corresponded to down-regulation.Dysregulation of Signal Transduction and Activator of Transcription-3(STAT-3) was found along with related changes in STAT-3 targets which occurred in an etiology-dependent fashion in HCC-free cirrhosis.In contrast,in HCC,such transcription dysregulations were not observed.CONCLUSION:We report that transcriptional dysregulations exist in HCC-free cirrhosis,are transiently observed prior to detectable HCC onset and may be appear like markers from cirrhosis to HCC transition. | Frédérique Caillot Céline Derambure Paulette Bioulac-Sage Arnaud Franois Michel Scotte Odile Goria Martine Hiron Maryvonne Daveau Jean-Philippe Salier | 2009 | World Journal of Gastroenterology2009，15，3： | 1 |
| 15 | Effect of dopaminergic substances on sleep/wakefulness in saline- and MPTP- treated mice 显示文摘 | Laloux C Derambure P Houdayer E | 2008 | J Sleep Res2008，17，： | 1 |
| 16 | Influence of pre-existing dementia on the risk of post-stroke epileptic seizures显示文摘 | Cordonnie C* Henon H Derambure P | 2005 | J Neurol Neurosurg Psychiat2005，7612，： | 1 |
| 17 | Effects of hypocaloric diet on respiratory manifestations in Willi-Prader syndrome 显示文摘 | Deschildre A Martinot A Fourier C Nguyen-Quang JM Hue V Derambure P Leclere F | 1995 | Areh Pediatr1995，2，11： | 1 |
| 18 | Management of restless legs and periodic movements of sleep显示文摘 | Monaca C Derambure P | 2004 | Rev Neurol2004，160，67： | 1 |
| 19 | Gene profiling pre- dicts rheumatoid arthritis responsiveness to IL-1Ra (anakinra) 显示文摘 | Bansard C Lequerr6 T Derambure C | 2011 | Rheumatology2011，50，2： | 1 |
| 20 | Motor cortex stimulation modulates defective central beta rhythms in pa tients with neuropathie pain显示文摘 | Reyns N Derambure P Duhamel A et at | 2013 | Clin Neurophysiol2013，124，4： | 1 |
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