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| 1 | 22-gauge core vs 22-gauge aspiration needle for endoscopic ultrasound-guided sampling of abdominal masses显示文摘AIM To compare the aspiration needle(AN) and core biopsy needle(PC) in endoscopic ultrasound-guided fine needle aspiration(EUS-FNA) of abdominal masses.METHODS Consecutive patients referred for EUS-FNA were included in this prospective single-center trial. Each patient underwent a puncture of the lesion with both standard 22-gauge(G) AN(Echo Tip Ultra; Cook Medical, Bloomington, Indiana, United States) and the novel 22 G PC(Echo Tip Pro Core; Cook Medical, Bloomington, Indiana, United States) in a randomized fashion; histology was attempted in the PC group only. The main study endpoint was the overall diagnostic accuracy, including the contribution of histology to the final diagnosis. Secondary outcome measures included material adequacy, number of needle passes, and complications.RESULTS Fifty six consecutive patients(29 men; mean age 68 years) with pancreatic lesions(n = 38), lymphadenopathy(n = 13), submucosal tumors(n = 4), or others lesions(n = 1) underwent EUS-FNA using both of the needles in a randomized order. AN and PC reached similar overall results for diagnostic accuracy(AN: 88.9 vs PC: 96.1, P = 0.25), specimen adequacy(AN: 96.4% vs PC: 91.1%, P = 0.38), mean number of passes(AN: 1.5 vs PC: 1.7, P = 0.14), mean cellularity score(AN: 1.7 vs PC: 1.1, P = 0.058), and complications(none). A diagnosis on the basis of histology was achieved in the PC group in 36(64.3%) patients, and in 2 of those as the sole modality. In patients with available histology the mean cellularity score was higher for AN(AN: 1.7 vs PC: 1.0, P = 0.034); no other differences were of statistical significance.CONCLUSION Both needles achieved high overall diagnostic yields and similar performance characteristics for cytological diagnosis; histological analysis was only possible in 2/3 of cases with the new needle. | William Sterlacci Athanasios D Sioulas Lothar Veits Pervin G?nüllü Guido Schachschal Stefan Groth Mario Anders Christos K Kontos Theodoros Topalidis Andrea Hinsch Michael Vieth Thomas R?sch Ulrike W Denzer | 2016 | World Journal of Gastroenterology2016，22，39： | 2 |
| 2 | Pubertal development inobese children and adolescents显示文摘 | Denzer C Weibel A Muche R | 2007 | Int J Obes(Lond)2007，31，10： | 1 |
| 3 | Generic integration of environmental decision support systems-state-of-the-art显示文摘 | Denzer R | 2005 | Environmental Modelling & Software2005，20，10： | 1 |
| 4 | Microstructure-based modeling of residual stresses in WC-12Co-sprayed coatings显示文摘 | KLUSEM ANN B DENZER R SVENDSEN B | 2012 | Journal of Thermal Spray Technology2012，21，： | 1 |
| 5 | Pubertal development in obese children and adolescents显示文摘 | Denzer C Weibel A Muche R | | 0，，10： | 1 |
| 6 | Pubertal development in obese children and adolescents显示文摘 | Denzer C Weibel A Muche R | 2007 | Int J Obes (Lond)2007，31，10： | 1 |
| 7 | Pubertal development in obese children and adolescents显示文摘 | Denzer C Weibel A Muche R | 2007 | Int J Obes (Lond)2007，31，： | 1 |
| 8 | Gender-specific prevalences of fatty liver in obese children and adolescents: roles of body fat distribution, sex steroids, and insulin resistance 显示文摘 | Denzer C Thiere D Muche R | 2009 | J Clin Endocrinol Metab2009，94，10： | 1 |
| 9 | Pubertal development in obese children and adolescents 显示文摘 | Denzer C Weibel A Muehe R | 2007 | Int J Obes ( Lond)2007，31，10： | 1 |
| 10 | Agrin bindsto the nerve-muscle basal lamina via laminin显示文摘 | Denzer AJ Brandenberger R Gesemann M | 1997 | J Cell Biol1997，137，3： | 1 |
| 11 | Pubertal development in obese children and adolescents显示文摘 | Denzer C Weibel A Muche R et a1 | 2007 | Int J Obes(Lond)2007，3，10： | 1 |
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