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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | Investigating different methods used for approximating pillar loads in longwall coal mines显示文摘Accurately estimating load distributions and ground responses around underground openings play a significant role in the safety of the operations in underground mines.Adequately designing pillars and other support measures relies highly on the accurate assessment of the loads that will be carried by them,as well as the load-bearing capacities of the supports.There are various methods that can be used to approximate mining-induced loads in stratified rock masses to be used in pillar design.The empirical methods are based on equations derived from large databases of various case studies.They are implemented in government approved design tools and are widely used.There are also analytical and numerical techniques used for more detailed analysis of the induced loads.In this study,two different longwall mines with different panel width-to-depth ratios are analyzed using different methods.The empirical method used in the analysis is the square-decay stress function that uses the abutment angle concept,implemented in pillar design software developed by the National Institute for Occupational Safety and Health(NIOSH).The first numerical method used in the analysis is a displacement-discontinuity(DD)variation of the boundary element method,LaModel,which utilizes the laminated overburden model.The second numerical method used in the analysis is Fast Lagrangian Analysis of Continua(FLAC)with the numerical modeling approach recently developed at West Virginia University which is based on the approach developed by NIOSH.The model includes the 2D slice of a cross-section along the width of the panel with the chain pillar system that also includes the different stratigraphic layers of the overburden.All three methods gave similar results for the shallow mine,both in terms of load percentages and distribution where the variation was more obvious for the deep cover mine.The FLAC3D model was observed to better capture the stress changes observed during the field measurements for both the shallow and deep cover cases.This study allowed us to see the shortcomings of each of these different methods.It was concluded that a numerical model which incorporates the site-specific geology would provide the most precise estimate for complex loading conditions. | Deniz Tuncay a Ihsan Berk Tulu a Ted Klemetti | 2021 | International Journal of Mining Science and Technology2021，31，1： | 2 |
| 3 | Effects of inlet flow field conditions on the performance of centrifugal compressor diffusers:straight channel diffuser显示文摘 | Deniz S Greitzer E M Cumpsty N A | 2000 | ASME Journal of Turbomachinery2000，122，1： | 1 |
| 4 | Multicolor single-molecule FRET to explore protein folding and binding显示文摘 | Gambin Y Deniz A A | | 0，，09： | 1 |
| 5 | The effect of high-flux hemodialysis on renal anemia显示文摘 | Deniz A Meltem A Alper A | 2004 | Journal of Nephrology2004，17，5： | 1 |
| 6 | Effect of respiratory muscle endurance training in patients with COPD undergoing pulmonary rehabilitation显示文摘 | Mador M Deniz O Aggarwal A | 2005 | Chest2005，128，： | 1 |
| 7 | Bidirectional switching of near IR emitting boradiazaindacene fluoro- phores显示文摘 | DENIZ E ISBASAR G C BOZDEMIR O A | 2008 | Org Lett2008，10，16： | 1 |
| 8 | Time-dependent changes in superoxide dismutase, catalase, xanthine dehydrogenase and oxldase activities in focal cerebral显示文摘 | Sermet A Tasdemir N Deniz B | 2000 | Cytobios2000，102，401： | 1 |
| 9 | Single-pair fluorescence resonance energy transfer on freely diffusing molecules: observation of forster distance dependence and subpo-pulations 显示文摘 | DENIZ A A DAHAN M GRUNWELL J R | 1999 | Proc Natl Acad Sci1999，96，： | 1 |
| 10 | A Novel Approach to Remote Laboratories显示文摘 | Deniz D Z Bulancak A Ozcan G | 2003 | Frontiers in Education2003，1，33： | 1 |
| 11 | The effect of head rotation on intraocular pressure in prone position:a randomized trial显示文摘 | Nuri Deniz M Erakgün A Sertz N | 2013 | Rev Bras Anesthesiol2013，63，2： | 1 |
| 12 | Cyclooxygenase-2 expression and its association with angiogenesis, Helicobacter Pylori, and clinico-Pathologic characteistics Of gas- triecarcinoma 显示文摘 | Deniz Y Taha A Usur C | 2008 | Pathol Res Pract2008，204，8： | 1 |
| 13 | The impact of different nasal packings on postoperative complications显示文摘 | DENIZ M CIFTCI Z ISIK A | 2014 | Am J Otolaryngol2014，35，： | 1 |
| 14 | Temporal and spatial patterns of precipitation variability for annual,wet,and dry seasons inTurkey显示文摘 | Unal Y S Deniz A Toros H | 2012 | International Journal of Climatology2012，32，3： | 1 |
| 15 | X-ray emission from plasmas created by smoothed KrF laser irradiation显示文摘 | Aglitskiy Y Lehecka T Deniz A | | 0，，09： | 1 |
| 16 | Effects of nutritional supple- mentation combined with conventional pulmonary rehabilitation in muscle-wasted chronic obstructive pulmonary disease: a prospec- tive, randomized and controlled study 显示文摘 | Gurgun A Deniz S Argin M | 2013 | Respirology2013，18，3： | 1 |
| 17 | Financial liberalization and banking efficiency:evi-denee from Turkey显示文摘 | MUSTAFA DINC MURAT TABIMCILAR | 2007 | Journal of Productivity Analysis2007，，： | 1 |
| 18 | Effect of respiratory muscle endurance training inpatients with COPD undergoing pulmonary re- habilitation显示文摘 | Mador MJ Deniz O Aggarwal A | 2005 | Chest2005，128，3： | 1 |
| 19 | Single-molecule protein folding:diffusion fluorescence resonance energy transfer studies of the denaturation of chymotrypsin inhibitor显示文摘 | Deniz A A Laurence T A Beligere G S | | 0，，： | 1 |
| 20 | A clinic's experiences in postoperative patient controlled ana/gesia 显示文摘 | Atim A Deniz S Orhan ME | 2009 | Agri2009，21，4： | 1 |
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