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210篇 您的检索式:作者名="DePinho"
    题名 作者 年代 出处 被引量
1Nature:研究鉴定出侵袭性胰腺癌细胞及其弱点显示文摘在一项新的研究中,来自美国德州大学MD安德森癌症中心的研究人员利用患者源性肿瘤异种移植(patient—derived tumorxenograft,PDx)和模式小鼠开展一系列临床前实验,鉴定出一种门卫蛋白(gatekee Perprotein)阻止胰腺癌细胞转化为一种极具侵袭性的细胞类型,并且也发现剔除这种门卫蛋白的疗法能够阻止这些癌细胞。这些发现有助为携带这种进展迅速的治疗抵抗性的胰腺癌细胞亚群的患者开发出潜在的疗法。Genovese, Giannicola Carugo, Alessandro Tepper, James Robinson, Frederick Scott Li, Liren Svelto, Maria Nezi, Luigi Corti, Denise Minelli, Rosalba Pettazzoni, Piergiorgio Gutschner, Tony Wu, Chia-Chin Seth, Sahil Akdemir, Kadir Caner Leo, Elisabetta Amin, Samirkumar Dal Molin, Marco Ying, Haoqiang Kwong, Lawrence N. Colla, Simona Takahashi, Koichi Ghosh, Papia Giuliani, Virginia Muller, Florian Dey, Prasenjit Jiang, Shan Garvey, Jill Liu, Chang-Gong Zhang, Jianhua Heffernan, Timothy P. Toniatti, Carlo Fleming, Jason B. Goggins, Michael G. Wood, Laura D. Sgambato, Alessandro Agaimy, Abbas Maitra, Anirban Roberts, Charles W. M. Wang, Huamin Viale, Andrea DePinho, Ronald A. Draetta, Giulio F. Chin, Lynda 2017现代生物医学进展2017,17,14:2
2Axis of ageing:telomeres,p53 and mitochondria显示文摘Sahin E DePinho RA 0,,06:1
3Hepatocellular carcinoma pathogenesis, from genes to envimnment显示文摘Farazi PA DePinho RA 2006Nat Rev Cancer2006,6,:1
4Context-Dependent Transformation of Adult Pancreatic Cells by Oncogenic K-Ras显示文摘Sharon Y. Gidekel Friedlander Gerald C. Chu Eric L. Snyder Nomeda Girnius Gregory Dibelius Denise Crowley Eliza Vasile Ronald A. DePinho Tyler Jacks 2009Cancer Cell2009,,5:1
5Cancer:crime and punish-mennt显示文摘Sharpless NE DePinho RA 2005Nature2005,436,7051:1
6Cancer-Crime and punishment显示文摘Sharpless NE DePinho RA 2005Nature2005,436,7051:1
7Telomerase is required to slow telomere shortening and extend replieative lifespan of HSCs during serial transplantation 显示文摘Allsopp R C Morin G B DePinho R 2003Blood2003,102,2:1
8Crime and punishment显示文摘Sharpless N E DePinho R A 2011Nature2011,426,:1
9Telomeres, stem cells, senescence and cancer显示文摘SHARPLESS N E DEPINHO R A 2004J Clin Invest2004,113,2:1
10The INK4A/ARF locus andits two gene products显示文摘Sharpless NE DePinho RA 1999Curr Opin Genet Dev1999,9,1:1
11Connecting chromosomes,crisis,and cancer J显示文摘Maser RS DePinho RA 2002Science2002,297,5581:1
12Mechanisms of colloidal natural organic matter foaling in ultrafihration 显示文摘COSTA A DEPINHO M ELIMELECH M 2006Journal of Membrane Science2006,281,:1
13constitutively active epidermal growth factor receptor cooperates with disruption of GI cell-cycle arrest pathways to induce glioma-like lesions in mice显示文摘Holland EC Hively WP DePinho RA 1998Genes Dev1998,12,23:1
14Telomeres and telomerase in cancer显示文摘Artandi S E DePinho R A 2010Carcinogenesis2010,31,1:1
15Cellular transformation by the MSP58 oncogene is inhibited by its physical interaction with the ]?TEN tumor suppressor显示文摘Okumura K Zhao M Depinho RA 2005Proc Natl Acad Sci S A2005,102,8:1
16Pancreatic cancer biology and ge-netics显示文摘Bardeesy N DePinho KA 0,,12:1
17Telomeres,stem cells,senescence and cancer显示文摘Sharpless NE Depinho RA 2004J Clin Invest2004,113,2:1
18Linking functional decline of telo meres, mitochondria and stem cells during ageing显示文摘Sahin E Depinho RA 2010Nature2010,464,7288:1
19Hepatocellular carcinoma pathoge-nesis:from genes to environment显示文摘Farazi P A DePinho R A 2006Nat Rev Cancer2006,6,9:1
20Telomeres and telomerase in cancer显示文摘Artandi S E DePinho R A 2010Carcinogenesis2010,31,:1
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