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		题名	作者	年代	出处	被引量
	1	Overexpression of Bax sensitizes prostate cancer cells to TGF-β induced apoptosis显示文摘NRP-154 is a tumorigenic epithelial cell line derived from the preneoplastic dorsal-lateral prostate of rats. These cells are exquisitely sensitive to TGF-β induced apoptosis. In contrast, we find that NRP-154 cells can sustain overexpression of exogenous Bax protein, which is different from non-tumor cells where Bax functions as a ubiquitous stimulator of apoptosis. NRP-154 cells stably overexpressing Bax show increased sensitivity to TGF-β induced apoptosis. The degree of TGF-β induced apoptosis displays high correlation with cleavage of Bax at the amino-terminus. Our data indicate that prostate cancer cells can host high levels of latent Bax which can be activated through post-translational modification.	PeiHuiLIN ZuiPAN LinZHENG NaLI DavidDANIELPOUR JianJieMA	2005	Cell Research2005，15，3：	2

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