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您的检索式：作者名="David Sulzer"
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| 1 | Prognostic impact of the Bismuth-Corlette classification:Higher rates of local unresectability in stageⅢb hilar cholangiocarcinoma显示文摘Background:The Bismuth-Corlette(BC)classification is used to categorize hilar cholangiocarcinoma by proximal extension along the biliary tree.As the right hepatic artery crosses just behind the left bile duct,we hypothesized that BCⅢb tumors would have a higher likelihood of local unresectability due to involvement of the contralateral artery.Methods:A retrospective review of a prospectively maintained database identified patients with hilar cholangiocarcinoma taken to the operating room for intended curative resection between April 2008 and September 2016.Cases were assigned BC stages based on preoperative imaging.Results:Sixty-eight patients were included in the study.All underwent staging laparoscopy after which 16 cases were aborted for metastatic disease.Of the remaining 52 cases,14 cases were explored and aborted for locally advanced disease.Thirty-eight underwent attempt at curative resection.After exclud-ing cases aborted for metastatic disease,the chance of proceeding with resection was 55.6%for BCⅢb staged lesions compared to 80.0%of BCⅢa lesions and to 82.4%for BCⅠ-Ⅲa staged lesions(P<0.05).About 44.4%of BCⅢb lesions were aborted for locally advanced disease versus 17.6%of remaining BC stages.Conclusions:When hilar cholangiocarcinoma is preoperatively staged as BCⅢb,surgeons should antici-pate higher rates of locally unresectable disease,likely involving the right hepatic artery. | Michael J Passeri Maria R Baimas-George Jesse K Sulzer David A Iannitti John B Martinie Erin H Baker Lee M Ocuin Dionisios Vrochides | 2020 | Hepatobiliary & Pancreatic Diseases International2020，19，2： | 3 |
| 2 | Nature:研究首次证实帕金森病部分上是一种自身免疫疾病显示文摘帕金森病是一种神经退行性疾病。这种疾病的一种关键特征是受损的a-突触核蛋白(alpha-synuclein)在帕金森病患者体内的一种被称作多巴胺能神经元的脑细胞中堆积。在一项新的研究中,来自美国哥伦比亚大学医学中心和拉荷亚过敏症与免疫学研究所等研究机构的研究人员发现首个直接的证据证实自身免疫反应在帕金森病中发挥着作用。 | David Sulzer, Francesca Garretti, Ellen Kanter, Julian Agin-Liebes, Elizabeth Phillips, Simon Mallal David Sulzer, Roy N. Alcalay, Lucien Cote, Christopher Liong, Elizabeth Phillips, Simon Mallal David Sulzer Curtis McMurtrey, William H. Hildebrand Xiaobo Mao, Valina L. Dawson, Ted M. Dawson Xiaobo Mao, Valina L. Dawson, Ted M. Dawson Valina L. Dawson Valina L. Dawson, Ted M. Dawson Ted M. Dawson Carla Oseroff, John Pham, John Sidney, Myles B. Dillon, Chelsea Carpenter, Daniela Weiskopf, Bjoern Peters, April Frazier, Cecilia S. Lindestam Arlehamn, Alessandro Sette Elizabeth Phillips, Simon Mallal | 2017 | 现代生物医学进展2017，17，27： | 0 |
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