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1篇 您的检索式：作者名="David R.Liu"

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		题名	作者	年代	出处	被引量
	1	An exciting time for genome editing: an interview with David R. Liu显示文摘In 1987,several Osaka University researchers discovered a special kind of clustered DNA repeats in bacteria.Within a few years,two other groups independently discovered the same phenomenon but no one knew its function at the time.Only a small handful of scientists studied this property from its discovery in 1987 to 2005.It was then that the function of these DNA repeats,which were named Clustered Regularly Interspaced Short Palindromic Repeats(CRISPR),was finally elucidated.Researchers found that CRISPR,when combined with its CRISPR-associated partner(Cas),is crucial for the functioning of the bacterial adaptive immune system against viral phage infection.CRISPR sequences can be transcribed into targeting RNA molecules,and Cas enzymes are guided by these RNAs to cut specific viral DNA loci,rendering resistance against the viral infection.	Weijie Zhao Kevin T.Zhao David R.Liu	2019	National Science Review2019，6，3：	0

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