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| 1 | Nonalcoholic fatty liver disease in patients with inflammatory bowel disease: Beyond the natural history显示文摘BACKGROUND Nonalcoholic fatty liver disease(NAFLD)is a frequently reported condition in patients with inflammatory bowel disease(IBD).Both intestinal inflammation and metabolic factors are believed to contribute to the pathogenesis of IBDassociated NAFLD.AIM To evaluate the prevalence of steatosis and liver fibrosis(LF)in a cohort of IBD patients and the identification of metabolic-and IBD-related risk factors for NAFLD and LF.METHODS IBD patients were consecutively enrolled from December 2016 to January 2018.Demographic,anthropometric and biochemical data were collected so as eating habits.Abdominal ultrasound and transient elastography were performed to evaluate the presence of NAFLD and LF respectively.RESULTS A total of 178 consecutive patients were enrolled and included in the analysis(95 Ulcerative colitis,83 Crohn’s disease).NAFLD was detected by imaging in 72(40.4%)patients.Comparison between patients with and without NAFLD showed no significant differences in terms of IBD severity,disease duration,location/extension,use of IBD-related medications(i.e.,steroids,anti-TNFs,and immunomodulators)and surgery.NAFLD was significantly associated with the presence of metabolic syndrome[MetS;odds ratio(OR):4.13,P=0.001]and obesity defined by body mass index(OR:9.21,P=0.0002).IBD patients with NAFLD showed higher caloric intake and lipid consumption than those without NAFLD,regardless disease activity.At the multivariate analysis,male sex,advanced age and high lipid consumption were independent risk factors for the development of NAFLD.An increased liver stiffness was detected in 21 patients(16%)and the presence of MetS was the only relevant factor associated to LF(OR:3.40,P=0.01).CONCLUSION In this study,we demonstrate that risk factors for NAFLD and LF in the IBD population do not differ from those in the general population. | Salvatore Magrì Danilo Paduano Fabio Chicco Arianna Cingolani Cristiana Farris Giovanna Delogu Francesca Tumbarello Mariantonia Lai Alessandro Melis Laura Casula Massimo C Fantini Paolo Usai | 2019 | World Journal of Gastroenterology2019，25，37： | 8 |
| 2 | Damage detection in beam structures based on frequency measurements 显示文摘 | Fabrizio V Danilo C | 2000 | Journal of Engineering Mechanics2000，126，7： | 1 |
| 3 | Deplo- ying multiple interconnected gateways in heterogeneous wireless sensor networks : An optimization approach 显示文摘 | ANTONIO C MAq'FEO C DANILO D D et at | 2010 | Computer Communications2010，33，： | 1 |
| 4 | Relief of pruritus and decrease in plasma histamine concentrations during erythropoietin therapy in patients with uremia显示文摘 | Sergio D Emanuela C Danilo V et a1 | 1992 | N Eng J Med1992，326，1： | 1 |
| 5 | Relif ofpruritus and decrese in plasna hiatanine concentvations during erythropoietin therapy in patients with arenia显示文摘 | Serigo D Emanuela C Danilo V | 1992 | N Engl J Med1992，326，： | 1 |
| 6 | Relief of pruritus anti decrease in plasma histamine concentrations during erythropoietin therapy in patients with uremia显示文摘 | Sergio D Emanuela C Danilo V | 1992 | N Engl J Med1992，326，： | 1 |
| 7 | Minimum Entro Pydeconvolution with Frequency-domain Constraints显示文摘 | Mauricio D S Danilo R V Alberta H C | 1994 | Geophysics1994，59，6： | 1 |
| 8 | Relief of pruritus and decrease in plasma histamine concentrations during erythropoietin therapy in patients with uremia显示文摘 | Sergio D Emanuela C Danilo V | 1992 | N Engl J Med1992，326，： | 1 |
| 9 | Influence of temperature and pH on xylitol production from xylose by Debaryomyces hansenii UFV-170 显示文摘 | Fabio C Sampaio Celia Alencar de Moraes Danilo De Faveri | 2006 | Process Biochemistry2006，41，3： | 1 |
| 10 | Atherosclero- sis, caveolae and caveolin-l显示文摘 | Pavlides S Gutierrez-Paiares J L Danilo C etal | 2012 | Adv Exp Med Biol2012，729，： | 1 |
| 11 | Relief of pruritus and decrease inplasma histamine concentrations during erythropoietin therapy in patientswith uremia显示文摘 | Sergio D Emanuela C Danilo V | 1992 | JMed1992，326，： | 1 |
| 12 | Relief of Pruritu and Decrease in Plasma Histamine Comcertrations during Ery 2 Thropoietin Therapy in Patients with Uremia显示文摘 | Sergio D Emanuela C Danilo V | 1992 | N Engl J Med1992，326，15： | 1 |
| 13 | Relief of pruritus and decrease in plasma histamine concentrations during erythropoietin therapy in patients with uremia显示文摘 | Sergio D Emanuela C Danilo V et la | 1992 | N Eng J Med1992，326，1： | 1 |
| 14 | Negative regulation of CD95 ligand gene expression by vitamin D3 in T lymphocytes显示文摘 | MARCO C CINZIA F DANILO D B | 2002 | The Journal of Immunology2002，168，： | 1 |
| 15 | Relief of pruritus and decrease inplasma histamine concentrations during erythropoietin therapy in patientswith uremia 显示文摘 | Sergio D Emanuela C Danilo V | 1992 | J Med1992，326，： | 1 |
| 16 | Biomass and composition of the phytoplankton in the south eastern large-scale distribution and rela- tionship with environmental variables during a spring cruise 显示文摘 | Danilo C Monica G Nora G | 2005 | Cont Shelf Res2005，25，： | 1 |
| 17 | 显示文摘 | Matjaz V Danilo S Robert C | 2006 | J Eur Ceram Soc2006，26，： | 1 |
| 18 | Relief of pruritus and decrease in plasma histamine concentrations during erythropoietin therapy in patients with uremia显示文摘 | Sergio D Emanuela C Danilo V | 1992 | N Engl J Med1992，326，15： | 1 |
| 19 | Damage detection in beam structures based on frequency measurements 显示文摘 | Fabrizio V Danilo C | 2000 | Journal of Engineering Mechanics2000，126，7： | 1 |
| 20 | Termination Analysis in Active Databases显示文摘 | Danilo Montesi Maria Bagnato C ritina Dalleara | 1999 | IEEE1999，，： | 1 |
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