|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 中国10城市儿童哮喘及其他过敏性疾病现状调查显示文摘近几十年来, 世界范围内哮喘、鼻炎、湿疹(过敏性和非过敏性)患病率尤其是儿童患病率显著增长, 室内环境的变化被怀疑是其后的重要原因. 过去20年, 中国的室内环境经历了举世瞩目的巨大变化, 人们承受了很多前所未有的(室内)环境污染暴露, 它们与日趋严重的儿童哮喘及其他过敏性疾病间虽被怀疑存在很强的关联, 但尚未得到足够的研究结果支撑. 2010 ~2012年, 对中国室内环境与儿童健康(China, Children, Homes, Health, 简称CCHH)展开调研, 阶段I对10个代表城市随机选取的幼儿园或小学的48219名1~8岁的儿童进行了问卷调查. 问卷包含国际儿童哮喘过敏研究(ISAAC)问卷的关于健康效应的核心问题并加上了考虑中国住宅、生活习惯和室外环境等特点的问题, 对其中的3~6岁儿童的数据进行了分析研究. CCHH调查的城市中确诊哮喘患病率为1.7%~9.8% (平均为6.8%), 相比于1990年的0.91%和2000年的1.50%有大幅增长. 喘息、鼻炎和特应性湿疹(过去12个月)的患病率分别为13.9%~23.7%, 24.0%~50.8%和4.8%~15.8%. 在调研关注的儿童疾病中, 太原儿童的患病率最低; 除了乌鲁木齐儿童哮鸣音患病率最高外, 其余疾病和症状上海儿童的患病率最高. 分析显示: 患病率和室外PM10浓度无显著相关性, 和人均GDP为指标的经济条件的关联性值得进一步研究; 患病率在湿润环境(主要指夏热冬冷且建筑无集中供暖的地区)中要高得多. | 张寅平 李百战 黄晨 杨旭 钱华 邓启红 赵卓慧 李安桂 赵加宁 张昕 屈芳 胡宇 阳琴 王娟 张铭 王芳 郑晓红 路婵 刘志坚 孙越霞 莫金汉 赵宜丽 刘炜 王婷婷 NORBACK Dan BORNEHAG Carl-Gustaf SUNDELL Jan | 2013 | 科学通报2013，58，25： | 38 |
| 2 | Indoor Allergen Levels and Household Distributions in Nine Cities Across China显示文摘Objective Chinese allergic subjects have high levels of sensitization to house dust mite(HDM) and other indoor allergens. This study quantifies common indoor allergen levels in Chinese households. Methods Dust samples were collected from nine cities. Major allergens Der p 1 and Der f 1 from Dermatophagoides pteronyssinus and D. farinae, and specific antigens of Blomia tropicalis, Tyrophagus putrescentiae, Acarus siro, and cockroach species Blattella germanica and Periplaneta americana were measured by ELISA. Results HDM allergens were found in dust samples from bedding in 95% of the Chinese households. The median levels varied from <0.006 to 9.2 μg/g of dust, depending on the city. The percentages of households having HDM allergen levels associated with the risk of developing allergy sensitization and asthma were 65% and 25%, respectively. Specific antigens of the storage mite and cockroach were only found in samples from the southern and tropical regions of China. Levels of mite allergens were generally higher in samples from bedding compared to samples from the living room, even for storage mites, whereas levels of cockroach antigens were higher in the living room samples. Conclusion HDM allergens are present in bedding dust samples from most Chinese households. Cities in southern and central China have relatively high levels of HDM major allergens compared to cities in northern and western China. Antigens of storage mites and cockroaches are not as common as HDM allergens. | ZHENG Yi Wu LAI Xu Xin ZHAO De Yu ZHANG Chun Qing CHEN Jian Jun ZHANG Luo WEI Qing Yu CHEN Shi LIU En Mei NORBACK Dan GJESING Birgitte ZHONG Nan Shan SPANGFORT D.Michael | 2015 | Biomedical and Environmental Sciences2015，28，10： | 24 |
| 3 | 太原市学龄前儿童哮喘、过敏性鼻炎及湿疹与出生前及早期家居环境的相关性显示文摘为了探讨出生前及早期家居生活环境与儿童的哮喘及过敏性疾病的相关性, 在山西省太原市区学龄前儿童(3700名)中开展了一项横断面流行病学研究. 研究采用问卷调查的方式, 问卷内容包括儿童的哮喘和相关过敏性疾病的患病情况, 采用了International Study on Asthma and Allergies in Childhood(ISAAC)的核心问卷; 儿童的家居生活环境采用了瑞典的Dampness in Buildings and Health(DBH)的问卷内容, 并根据中国的生活习惯进行了部分调整. 通过多因素Logistic回归分析并调整了儿童年龄、性别、家族遗传, 市区或郊区/农村, 被动吸烟和母乳喂养, 结果显示, 出生前(指母亲怀孕前一年或/和怀孕期间)居住地添置新家居(HNF)与儿童报告的既往哮鸣音[比对比(OR) 1.23, 95%置信区间CI(1.03~1.48)], 及过去12个月内的哮鸣音(1.24, 1.00~1.54)、鼻炎症状(1.26, 1.06~1.51)以及湿疹(1.42, 1.01~1.99)呈正相关. 在0~1岁间的HNF与过去12个月的哮鸣音症状, 及0~1岁间家里新装修(HND)与儿童的既往鼻炎及过去12个月鼻炎和湿疹的症状均呈现正相关. 室内发霉的迹象或室内潮湿几乎与所有儿童的哮喘和过敏性疾病的症状呈现更强的正相关(OR范围在1.23~1.85, P〈0.05). 进一步相互调整了出生前HNF和室内发霉或潮湿的因素, 所有的显著性结果均没有明显变化. 本次研究表明, 出生前居住地添置新家具和室内发霉或潮湿是太原市学龄前儿童哮喘和相关过敏性疾病及症状的独立危险因素. | 赵卓慧 张昕 刘冉冉 NORBACK Dan WIESLANDER Gunilla 陈杰 SUNDELL Jan | 2013 | 科学通报2013，58，25： | 13 |
| 4 | Prenatal and early life home environment exposure in relation to preschool children's asthma, allergic rhinitis and eczema in Taiyuan, China显示文摘Prenatal and early life home environment might be related to children’s asthma or allergic diseases later in life.A cross-sectional epidemiological study was designed and a questionnaire survey was performed in 3700 preschool children in urban areas in Taiyuan,Shanxi Province,China.Questions on children’s asthma and allergic diseases from the International Study on Asthma and Allergies in Childhood(ISAAC)were integrated with questions on home environment from the Swedish Dampness in Buildings and Health(DBH)study,appropriately modified for Chinese life habits.By multivariate regression analyses controlling for age,gender,heredity,location in urban/suburban or rural areas,environmental tobacco smoke(ETS)and breastfeeding,we found that home new furniture(HNF)before birth(referring to 1 year before pregnancy and during pregnancy)was positively associated with wheezing ever(odds ratio(OR)1.23 with 95%CI of 1.03–1.48)and wheezing last 12 months(1.24,1.00–1.54),allergic rhinitis(AR)(1.26,1.06–1.51),and eczema(1.42,1.01–1.99).HNF between 0–1 years old was also positively associated with wheezing last 12 months.Home new decoration(HND)during 0–1 years old was positively associated with AR symptoms and eczema symptoms,more in the last 12 months.Stronger positive associations were found for signs of home mold and dampness with almost all children’s asthmatic and allergic symptoms(OR ranging from 1.23–1.85,P<0.05).By mutual adjustment between HNF before children’s birth and home mold or dampness,all the significance remained unchanged.Prenatal HNF and home mold or dampness was independently associated with children’s asthmatic and allergic diseases later in life. | ZHAO ZhuoHui ZHANG Xin LIU RanRan NORBACK Dan WIESLANDER Gunilla CHEN Jie SUNDELL Jan | 2013 | Chinese Science Bulletin2013，58，34： | 13 |
| 5 | 住房特征及室内环境与乌鲁木齐儿童哮喘、过敏性疾病及肺炎的相关性显示文摘为了探讨乌鲁木齐市学龄前儿童哮喘, 过敏性疾病和肺炎的患病率, 及其与住宅和家居环境因素的相关性, 开展了一项包括4618名学龄前儿童的横断面流行病学调查研究. 参与调查的儿童平均年龄4.7±0.9岁, 男孩占53.7%, 调查应答率81.7%. 儿童哮喘及过敏性疾病的调查, 采用了International Study on Asthma and Allergies in Childhood (ISAAC) 的核心问卷; 儿童家居住宅及生活环境采用了瑞典的Dampness in Buildings and Health (DBH) 的问卷, 并根据当地的住房和生活习惯进行了部分调整. 结果显示, 经医生诊断的哮喘和过敏性鼻炎(AR)及肺炎的阳性报告率分别为3.6%, 8.7%和40.9%. 过去12个月内, 约1/4的儿童报告有哮鸣音, 约40%的儿童有AR症状. 调整了混杂因素后, 室内发霉/潮湿与过去12个月内儿童哮鸣音的发生 (比对比OR, 1.33, 95%置信区间1.07~1.66)和AR症状 (1.34, 1.09~1.64) 医生诊断的肺炎 (1.33, 1.09~1.62)呈显著性正相关. 木质地板材料、PVC或铺设地毯、及使用墙纸、油漆或木质的墙面, 与过去12个月的AR症状呈正相关. 室内吸烟 (ETS) 和哮鸣音 (1.23, 1.04~1.46)以及肺炎的发生(1.24, 1.07~1.45)均呈现正相关. 本次调查表明乌鲁木齐市学龄前儿童有较高的哮喘和过敏性疾病症状及医生诊断的肺炎阳性报告率. 室内发霉或潮湿的现象及室内吸烟和含挥发性有机化学物的室内装修装饰材料等, 是儿童过敏性疾病和肺炎的危险因素. | 王婷婷 赵卓慧 姚华 王淑兰 NORBACK Dan 陈杰 马金凤 冀晓丽 王丽 SUNDELL Jan | 2013 | 科学通报2013，58，25： | 9 |
| 6 | Housing characteristics and indoor environment in relation to children's asthma, allergic diseases and pneumonia in Urumqi, China显示文摘In order to evaluate the prevalence of childhood asthma,allergic diseases and pneumonia in Urumqi City,China,as well as its associations with housing and home characteristics,a cross-sectional study was performed in 4618 children(81.7%response rate,average age 4.7±0.9 year,boys accounting for 53.7%).Questions on children’s asthma and allergic diseases were from the International Study on Asthma and Allergies in Childhood(ISAAC)and were integrated with questions on the home environment from the Dampness in Buildings and Health(DBH)study,slightly modified to account for Chinese building characteristics and life habits.The prevalences of physician diagnosed asthma,allergic rhinitis(AR)and pneumonia were 3.6%,8.7%and 40.9%,respectively.One fourth of children reported wheezing and more than 40%AR symptoms in the last 12 months.Controlling for confounding factors,positive associations were found for home mold/dampness and wheezing(adjusted odds ratio,aOR 1.33,95%CI 1.07 1.66),AR symptoms(1.34,1.09 1.64)last 12 months and physician diagnosed pneumonia(1.33,1.09 1.62).Floor material by wood,PVC or carpeting;and walls by wallpaper,painting or wood material,were positively associated with AR symptoms.Home environmental tobacco smoke(ETS)was positively associated with wheezing(1.23,1.04 1.46)and pneumonia(1.25,1.07 1.45).In conclusion,there was a relatively high prevalence of asthmatic and AR symptoms and diagnosed pneumonia in preschool children in Urumqi.Home signs of mold growth or dampness,windowpane condensation,as well as ETS and interior surface materials emitting chemicals were risk factors for allergic symptoms and pneumonia. | WANG TingTing ZHAO ZhuoHui YAO Hua WANG ShuLan NORBACK Dan CHEN Jie MA JinFeng JI XiaoLi WANG Li SUNDELL Jan | 2013 | Chinese Science Bulletin2013，58，34： | 9 |
| 7 | 重庆市学前儿童家长病态建筑综合征与住宅环境的关系显示文摘通过问卷调查研究了住宅环境中病态建筑综合征(sick Building syndrome,SBS)患病率和相关的危险因素.在2010年12月到2011年4月期间,课题组通过对重庆市的幼儿园进行随机抽样,一共有5299名3-6岁儿童的父亲或母亲回答并返回了调查问卷.儿童家长的SBS患病率(每周出现SBS的百分比)如下:一般性症状为11.4%;黏膜性症状为7.1%;皮肤性症状为4.4%.应用多元逻辑回归(通过控制家长的性别和哮喘/过敏性鼻炎/湿疹的影响)方法的分析结果表明:住宅靠近交通干线或高速公路是一般性症状、黏膜性症状和皮肤性症状的强烈危险因素(调整比值比aOR分别为:aOR=2.16,P〈0.001;aOR=2.69,P〈0.001;aOR=1.63,P〈0.01);装修是一般性症状、黏膜性症状和皮肤性症状的危险因素(aOR分别为:aOR=2.00,P〈0.001:aOR=1.66,P〈0.01:aOR=1.66,P〈0.05);新家具是一般性症状和皮肤性症状的危险因素(aOR分别为:aOR=2.16,P〈0.001;aOR=1.67,P〈0.01).潮湿问题(霉点、湿点、水损和窗户凝水)、报告出现蟑螂、老鼠、蚊子/苍蝇及使用熏香均是SBS的危险因素.保护性因素包括每天清洁儿童的卧室和经常晾晒被褥.本研究表明成年人的病态建筑综合征与住宅环境相关. | 王娟 李百战 阳琴 王晗 NORBACK Dan SUNDELL Jan | 2013 | 科学通报2013，58，25： | 7 |
| 8 | Sick building syndrome among parents of preschool children in relation to home environment in Chongqing, China显示文摘The prevalence and risk factors of sick building syndrome(SBS)symptoms in domestic environments were studied by a questionnaire survey on the home environment.Parents of 5299 3–6 years old children from randomly selected kindergartens in Chongqing,China returned completed questionnaires between December 2010 and April 2011.The prevalence of parents’SBS symptoms(often(every week)compared with never)were:11.4%for general symptoms,7.1%for mucosal symptoms and 4.4%for skin symptoms.Multiple logistic regressions were applied controlling for gender and asthma/allergic rhinitis/eczema.Living near a main road or highway was a strong risk factor for general symptoms(adjusted odds ratio,aOR=2.16,P<0.001),skin symptoms(aOR=2.69,P<0.001),and mucosal symptoms(aOR=1.63,P<0.01).Redecoration was a risk factor for general symptoms(aOR=2.00,P<0.001),skin symptoms(aOR=1.66,P<0.01),and mucosal symptoms(aOR=1.66,P<0.05).New furniture was a risk factor for general symptoms(aOR=2.16,P<0.001)and skin symptoms(aOR=1.67,P<0.01).Dampness related problems(mould spot,damp stain,water damage and condensation)were all risk factors for SBS symptoms,as was the presence of cockroaches,rats,and mosquitoes/flies and use of incense.Protective factors include cleaning the child’s bedroom every day and frequently exposing bedding to sunshine.In conclusion,adults’SBS symptoms were related to factors of the home environment. | WANG Juan LI BaiZhan YANG Qin WANG Han NORBACK Dan SUNDELL Jan | 2013 | Chinese Science Bulletin2013，58，34： | 6 |
| 9 | 太原市初中学校室内外环境与儿童不良建筑综合征的相关性显示文摘为了解初中学校儿童不良建筑综合征(sickbuildingsyndrome,SBS)、哮喘等疾病的发病率以及室内外环境污染水平和疾病的相关性,在山西省太原市城区初中学校开展了一项横断面研究.本研究采取整群抽样的方法,随机选取10所学校,问卷调查共发放2209份,其中有效问卷1993份(应答率为90.2%).参与调查的学生平均年龄为13岁(年龄范围11~15岁),其中女孩占49-3%.问卷内容包括SBS症状、哮喘及其他相关疾病的患病情况,SO,,N02和03环境影响因素的测量通过被动吸附采样,以及多因素Logistic回归分析疾病与环境因素的相关性.结果显示,儿童鼻黏膜炎(17.6%)、鼻塞(16.4%)、喉咙干燥(14.9%)、疲乏(20.7%)等症状患病率较高.室内N02与鼻黏膜炎、喉咙干燥、头疼、恶心、湿疹症状呈现正相关(比对比(0R)和95%置信区间(c1)分别为1.16,1.01~1.33;1.16,1.00~1.34;1.24,1.02-1.52;1.30,1.04-1.63;1.86,1.19-2.90).室内03仅与医生诊断哮喘呈现正相关(1-36,1.02-1.80).室内S02几乎与所有儿童SBS的症状呈现显著性相关.此外,室内与室外浓度的比值也与部分SBS症状正相关.本研究表明儿童不良建筑综合征与教室室内外环境相关. | 刘冉冉 赵卓慧 董川 NORBACK Dan 张昕 | 2014 | 科学通报2014，59，12： | 4 |
| 10 | The effect of building dampness and type of building on eye,nose and throat symptoms in Swedish hospitals显示文摘 | KLAS NORDSTRoM DAN NORBaCK GUNILLA W | 1999 | J Environ Med1999，1，： | 1 |
| 11 | A comparison of indoor air pollutants in Japan and Sweden;formaldehyde,mitrogen dioxide,and chlorinated volatile organic compounds显示文摘 | Kiy Sakai Dan Norback | 2004 | Environment Research2004，94，2004： | 1 |
| 12 | A comparison of indoor air pollutants in Japan and Sweden: formaldehyde, nitrogen dioxide, and chlorinated volatile organic compounds 显示文摘 | Kiyoshi Sakai Dan Norback | 2004 | Environment Research2004，94，2004： | 1 |
| 13 | Indoor metabolites and chemicals outperform microbiome in classifying childhood asthma and allergic rhinitis显示文摘Indoor microorganisms impact asthma and allergic rhinitis(AR),but the associated microbial taxa often vary extensively due to climate and geographical variations.To provide more consistent environmental assessments,new perspectives on microbial exposure for asthma and AR are needed.Home dust from 97 cases(32 asthma alone,37 AR alone,28 comorbidity)and 52 age-and gender-matched controls in Shanghai,China,were analyzed using high-throughput shotgun metagenomic sequencing and liquid chromatography-mass spectrometry.Homes of healthy children were enriched with environmental microbes,including Paracoccus,Pseudomonas,and Psychrobacter,and metabolites like keto acids,indoles,pyridines,and flavonoids(astragalin,hesperidin)(False Discovery Rate<0.05).A neural network co-occurrence probability analysis revealed that environmental microorganisms were involved in producing these keto acids,indoles,and pyridines.Conversely,homes of diseased children were enriched with mycotoxins and synthetic chemicals,including herbicides,insecticides,and food/cosmetic additives.Using a random forest model,characteristic metabolites and microorganisms in Shanghai homes were used to classify high and low prevalence of asthma/AR in an independent dataset in Malaysian schools(N=1290).Indoor metabolites achieved an average accuracy of 74.9%and 77.1%in differentiating schools with high and low prevalence of asthma and AR,respectively,whereas indoor microorganisms only achieved 51.0%and 59.5%,respectively.These results suggest that indoor metabolites and chemicals rather than indoor microbiome are potentially superior environmental indicators for childhood asthma and AR.This study extends the traditional risk assessment focusing on allergens or air pollutants in childhood asthma and AR,thereby revealing potential novel intervention strategies for these diseases. | Yu Sun Hao Tang Shuang Du Yang Chen Zheyuan Ou Mei Zhang Zhuoru Chen Zhiwei Tang Dongjun Zhang Tianyi Chen Yanyi Xu Jiufeng Li Dan Norback Jamal Hisham Hashim Zailina Hashim Jie Shao Xi Fu Zhuohui Zhao | 2023 | Eco-Environment & Health2023，2，4： | 0 |
| 14 | 太原市中学PM(2.5)元素组成与健康风险评估显示文摘为测定太原市初中学校大气细颗粒物(PM_(2.5))的浓度和元素组成,并对暴露于PM_(2.5)中的致癌元素进行环境健康风险评价。文章采取整群抽样的方法,在太原市城区随机选取10所学校,通过小流量分级采样器对PM_(2.5)进行采样,并用电感耦合等离子体质谱仪(ICP-MS)对PM_(2.5)中的元素进行分析。结果显示,采样期间PM_(2.5)的平均浓度为(162.99±107.43)μg/m^3。使用ICP-MS共检测出PM_(2.5)中的66种元素,其中,元素S的含量最高,地壳元素(Si、K、Ca、Fe和Al)次之。元素S、As、Cd、Co、Cr和Ni的平均浓度分别为16 259、38.80、9.25、2.87、84.19和25.12 ng/m^3。健康风险评价结果显示,学校中男生经呼吸途径暴露于各元素的非致癌风险和癌症风险较高。不同人群经呼吸途径暴露于元素Mn的非致癌风险较高(HQ>1),暴露于元素Cr的致癌风险较高(R_i>10^(-4))。 | 白旭 张泽斐 张一菲 赵卓慧 Norback Dan 张昕 | 2020 | 山西大学学报(自然科学版)2020，43，3： | 0 |
| 15 | Sick building syndrome,perceived odors,sensation of air dryness and indoor environment in Urumqi,China显示文摘In order to evaluate the perceived home indoor air quality,as well as sick building syndrome(SBS) in areas with typical arid continental climate such as Urumqi,northwest of China,a cross-sectional study including 4,260 parents of children(1–8 years) was performed by a questionnaire survey in winter season in 2011.The sensation of air dryness(weekly/sometimes) in the last 3 months had the highest proportion of reports by more than half of the parents(57.4 %),followed by perceived stuffy odor(40.6 %),unpleasant odor(27.0 %),tobacco smoke odor(25.5 %),sensation of humid air(17.9 %),pungent odor(11.7 %) and moldy odor(9.5 %),respectively.The prevalence of SBS symptoms in the same time period was40.4 % for general symptom,47.7 % for mucosal symptom and 9.5 % for skin symptom,respectively.There were significant associations between perceived odors/sensation of air dryness and SBS symptoms(ORs range 1.39–1.42).Additionally,the OR values increased with an increase of the OH score(P \ 0.05).Dampness,the presence of cockroaches and mosquitoes/flies,prenatal exposure to decoration and close to traffic were all risk factors of SBS symptoms.However,frequently putting bedding to sunshine was potentially a protective factor.In conclusion,adults' perceptions of odors and sensation of air dryness are related to SBS symptoms and home environmental factors in Urumqi,China. | Zhijing Lin Tingting Wang Dan Norback Haidong Kan Jan Sundell Zhuohui Zhao | 2014 | Chinese Science Bulletin2014，59，35： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员