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| 1 | Expression of bcI-2 gene family during resection induced liver regeneration:Comparison between hepatectomized and sham groups显示文摘AIM:During liver regeneration cellular proliferation and apoptosis result in tissue remodeling to restore normal hepatic mass and structure.Main regulators of the apoptotic machinery are the Bcl-2 family proteins but their roles are not well defined throughout the liver regeneration.We aimed to analyze the expression levels of bcl-2 gene family members during resection induced liver regeneration.METHODS:We performed semi-quantitative RT-PCR to examine the expression level of bak, bax, bcl-2 and bcl-XL in 70% hepatectomized rat livers during the whole regeneration process and compared to that of the sham and normal groups.RESULTS:The expression of bak and baxwas decreased whereas that of bcl-2 and bcl-XL was increased in hepatectomized animals compared to normal liver at most time points.We also reported for the first time that sham group of animals had statistically significant higher expression of bak and bax than hepatectomized animals.In addition, the area under the curve (AUC) values of these genes was larger in sham groups than the hepatectomized groups.CONCLUSION: The expression changes of bak, bax, bcl-2 and bcl-XL genes are altered not only due to regeneration,but also due to effects of surgical operations. | Kamil Can Akcali Aydin Dalgic Ahmet Ucar Khemaeis Ben Haj Dilek Guvenc | 2004 | World Journal of Gastroenterology2004,10,2: | 13 |
| 2 | Comparison of double balloon enteroscopy in adults and children显示文摘AIM: To compare results of double balloon enteroscopy (DBE) procedures in pediatric and adult patients. METHODS: The medical files of patients who underwent DBE at Gazi University School of Medicine, Ankara, Turkey between 2009 and 2011 were examined retrospectively. Adult and pediatric patients were compared according to DBE indications, procedure duration, final diagnosis, and complications. DBE procedures were performed in an operating room under general anesthesia by two endoscopists. An oral or anal approach was preferred according to estimated lesion sites. Overnight fasting of at least 6 h prior to the start of the procedure was adequate for preprocedural preparation of oral DBE procedures. Bowel cleansing was performed by oral administration of sennosides A and B solution, 2 mL/kg, and anal saline laxative en-ema. The patients were followed up for 2 h after the procedure in terms of possible complications. RESULTS: DBE was performed in 35 patients (5 pediatric and 30 adult). DBE procedures were performed for abdominal pain, chronic diarrhea, bleeding, chronic vomiting, anemia, and postoperative evaluation of anastomosis. Final diagnosis was diffuse gastric angiodysplasia (n = 1); diffuse jejunal angiodysplasia (n = 1); ulceration in the bulbus (n = 1); celiac disease (n = 1); low differentiated metastatic carcinoma (n = 1); PeutzJeghers syndrome (n = 1); adenomatous polyp (n = 1) and stricture formation in anastomosis line (n = 1). During postprocedural follow-up, abdominal pain and elevated amylase levels were noted in three patients and one patient developed abdominal perforation. CONCLUSION: With the help of technological improvements, we may use enteroscopy as a safe modality more frequently in younger and smaller children. | Odul Egritas Gurkan Tarkan Karakan Ibrahim Dogan Buket Dalgic Selahattin Unal | 2013 | World Journal of Gastroenterology2013,19,29: | 11 |
| 3 | Differential diagnosis in ulcerative colitis in an adolescent: Chronic granulomatous disease needs extra attention显示文摘Chronic granulomatous disease(CGD) is a primary immune deficiency that is commonly diagnosed under the age of 5 years(95%) and is rarely seen in adulthood. CGD may manifest as inflammatory bowel disease(IBD) in childhood. Without proper diagnosis, these patients may be monitored for years as IBD; some may even be regarded as steroid-resistant ulcerative colitis(UC) and end up having a colectomy. In this case report, we described a patient who had been followedup for years as UC and subsequently underwent colectomy, but was finally diagnosed in adulthood as primary immune deficiency. | Daniel Kotlarz Odul Egritas Gurkan Zehra Sule Haskologlu Ozgur Ekinci Aysel Aksu Unlusoy Neslihan Gürcan Kaya Jacek Puchalka Cristoph Klein Buket Dalgic | 2017 | World Journal of Gastrointestinal Pathophysiology2017,8,2: | 2 |
| 4 | Anatomical study of the cavernous sinus emphasizing operative approaches 显示文摘 | Dalgic A Boyaci S Aksoy K | 2010 | Turk Neurosurg2010,20,2: | 1 |
| 5 | Niche marketing revisited:Concept,applications and some European cases显示文摘 | Dalgic T Leeuw M | 1994 | European Journal of Marketing1994,28,4: | 1 |
| 6 | Polymorphism in the P2X7 gene increases susceptibility to extrapulmonary tu- berculosis in Turkish children显示文摘 | Tekin D Kayaalti Z Dalgic N | 2010 | Pediatr Infect Dis J2010,29,8: | 1 |
| 7 | Laser therapy in chronic cervicitis显示文摘 | Dalgic H Kuscu NK | | 0,,02: | 1 |
| 8 | Comparison of the effects of two legal blood alcohol limits: the presence of alcohol in traffic accidents according to category of drlver in izmir, Turkey显示文摘 | Karakus A Idiz N Dalgic M | 2015 | Trahtlc lnjuryPrevention2015,16,5: | 1 |
| 9 | Laser therapy in chronic cervicitis显示文摘 | Dalgic H Kuscu N K | 2001 | Arch Gynecol Obstet2001,265,2: | 1 |
| 10 | A variant Muckle-Wells syndrome with a novel mutation in CIAS1 gene responding to anakinra显示文摘 | Dalgic B Egritss O Sail S | 2007 | Pediatr Nephrol2007,22,: | 1 |
| 11 | Biogas production from olive pomace Resources显示文摘 | Ali R Tekin A Coskun Dalgic | 2000 | Conservation and Recycling2000,,30: | 1 |
| 12 | Laser therapy in chronic cervicitis显示文摘 | Dalgic H Kuscu NK | 2001 | Arch Gynecol Obstet2001,265,2: | 1 |
| 13 | Successful treatment ofmuitidrug-resistant Acinetobacter baumanii ventriculitis with in-travenous and intraventricular colistin显示文摘 | Dalgic N Ceylan Y Sancar M | 2009 | Ann Trop Paediatr2009,29,2: | 1 |
| 14 | True number portability and advanced call screening in a SIP based IP telephony system显示文摘 | Dalgic I Borella M Dean R | | 0,,: | 1 |
| 15 | Laser therapy in chronic cervicitis显示文摘 | Dalgic H Kuscu N K | 2001 | Arch Gynecol Obstet2001,265,2: | 1 |
| 16 | Polymorphism in the p2x7 gene increases susceptibility to extrapulmonary tuberculosis in Turkish children显示文摘 | Tekin D Kayaalti Z Dalgic N | | 0,,: | 1 |
| 17 | Effects of omeprazole over voice quality in muscle tension dysphonia patients with laryngopharyngeal reflux显示文摘 | Kandogan T Aksoy G Dalgic A | 2012 | Iran Red Crescent Med J2012,14,12: | 1 |
| 18 | Successful treatment of multidrug-resistant Acinetobacter baumannii ventriculitis with intravenous and intraventricular colistin显示文摘 | Dalgic N Ceylan Y Sancar M | 2009 | Annals of Tropical Paediatrics2009,29,: | 1 |
| 19 | A fuzzy logic-based model for noise control at industrial workplaces显示文摘 | Aluclu I Dalgic A Toprak Z F | 2008 | Applied Ergonomics2008,39,3: | 1 |
| 20 | Arg753Gln polymorphism of the human Toll-like receptor 2 gene from infection to disease in pediatric tuberculosis显示文摘 | Dalgic N Tekin D Kayaalti Z | 2011 | Hum Immunol2011,72,5: | 1 |