|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Voxel-based magnetic resonance imaging investigation of poor and preserved clinical insight in people with schizophrenia显示文摘AIM To define regional grey-matter abnormalities in schizophrenia patients with poor insight(Insight-),relative to patients with preserved clinical insight(Insight+),and healthy controls.METHODS Forty stable schizophrenia outpatients(20 Insight-and 20 Insight+) and 20 healthy controls underwent whole brain magnetic resonance imaging(MRI).Insight in all patients was assessed using the Birchwood Insight Scale(BIS;a self-report measure).The two patient groups were preselected to match on most clinical and demographic parameters but,by design,they had markedly distinct BIS scores.Voxel-based morphometry employed in SPM8 was used to examine group differences in grey matter volumes across the whole brain.RESULTS The three participant groups were comparable in age [F(2,57) = 0.34,P = 0.71] and the patient groups did not differ in age at illness onset [t(38) = 0.87,P = 0.39].Insight-and Insight+ patient groups also did not differ in symptoms on the Positive and Negative Syndromes scale(PANSS):Positive symptoms [t(38) = 0.58,P = 0.57],negative symptoms [t(38) = 0.61,P = 0.55],general psychopathology [t(38) = 1.30,P = 0.20] and total PANSS scores [t(38) = 0.21,P = 0.84].The two patient groups,as expected,varied significantly in the level of BIS-assessed insight [t(38) = 12.11,P < 0.001].MRI results revealed lower fronto-temporal,parahippocampal,occipital and cerebellar grey matter volumes in Insightpatients,relative to Insight+ patients and healthy controls(for all clusters,family-wise error corrected P < 0.05).Insight+ patient and healthy controls did not differ significantly(P > 0.20) from each other.CONCLUSION Our findings demonstrate a clear association between poor clinical insight and smaller fronto-temporal,occipital and cerebellar grey matter volumes in stable long-term schizophrenia patients. | Adegboyega Sapara Dominic H Ffytche Michael A Cooke Steven CR Williams Veena Kumari | 2016 | World Journal of Psychiatry2016，6，3： | 3 |
| 2 | Effect of capsaicin and dihydrocapsaicin on in vitro blood coagulation and platelet aggregation显示文摘 | Murray J A Kiran D K A Dominic P G | 2009 | Thrombosis Research2009，124，6： | 1 |
| 3 | An equivalent linear algorithm with frequency-and pressure-dependent moduli and damping for the seismic analysis of deep sites显示文摘 | Dominic A Eduardo K | 2002 | Soil Dynamics and Earthquake Engineering2002，22，912： | 1 |
| 4 | A new distance between two bodies of evidence显示文摘 | Jousselme A L Dominic G Bosse E | 2001 | Information Fusion2001，2，2： | 1 |
| 5 | Evolution of the specific surface area and of crystal morphology of Arctic fresh snow during the ALERT 2000 显示文摘 | Cabanes A Legagneux L Domin F | 2002 | Atmos Environ2002，36，： | 1 |
| 6 | A new dis-tance between two bodies of evidence显示文摘 | JOUSSELME A L DOMINIC G BOSSE E | 2001 | Information Fu-sion2001，2，2： | 1 |
| 7 | Surprisingly small HONO emissions from snow surfaces at Browning Pass, Antarctica 显示文摘 | Beine H J Amoroso A Domine F | 2006 | Atmos Chem Phys2006，6，： | 1 |
| 8 | A new distance between two bodies of evidence 显示文摘 | Jousselme A L Dominic G Bosse E | 2001 | Information Fusion2001，2，： | 1 |
| 9 | Water Resistant Solid Lewis Acid Catalysts: Meerwein-Ponndoif-Verley and Op- penauer Reactionscatalyzed by Tin-Beta Zeolite 显示文摘 | Corma A Domine M E Valencia S | 2003 | J Catal2003，215，2： | 1 |
| 10 | Quantifying the relationship between co-expression,co-regulation and gene function显示文摘 | Dominic J A Isaac S K Atul J B | 2004 | BMC Bioinformatics2004，5，： | 1 |
| 11 | Fluxes of nitrates between snow surfaces and the atmosphere in the European high Arctic 显示文摘 | Beine H J Domine F lanniello A | 2003 | Atmos Chem Phys2003，3，： | 1 |
| 12 | Technical basis and proposal for deriving sediment quality criteria for metals显示文摘 | Gerald T A Dominic M D T David J H | 1996 | Environmental Toxicology and Chemistry1996，15，12： | 1 |
| 13 | Dietary o- mega -3 fatty acid supplementation increases the rate of muscle protein synthesis in older adults: a randomized controlled trial 显示文摘 | Gordon IS Philip A Dominic NR | 2011 | Am J Clin Nutr2011，93，： | 1 |
| 14 | Skeletal muscle,cytokines,andox id at ive st ress i n end st age renal d isea se显示文摘 | Raj D S Dominic E A Pa A | 2005 | K i ndeyInt2005，68，5： | 1 |
| 15 | A structural equation modeling approach for the adoption of cloud computing to enhance the Malaysian Healthcare Sector显示文摘 | Ratnarn K A Dominic P D D Ramayah T | 2014 | Journal of medical systems2014，38，8： | 1 |
| 16 | Flow Batteries for Enhancing Wind Power Integration显示文摘 | DOMINIC D BANHAM H GARETH A | 2012 | IEEE Transaction on Power System2012，27，3： | 1 |
| 17 | Microorganisms in dry polar snow are involved in the exchanges of reactive nitrogen species with the atmosphere 显示文摘 | Amoroso A Domine F Morin S | 2010 | Environmental Science & Technology2010，44，2： | 1 |
| 18 | Skeletal musle, cytokines, and oxidative stress in end stage renal disease 显示文摘 | Dominic SCR Elizabeth A Dominic AP | 2005 | Kid- ney International2005，68，5： | 1 |
| 19 | Identification of small molecule inhibitors of hypoxia-inducible factor 1 transcriptional activation pathway显示文摘 | Annamaria R Badarch U Dominic A | 2002 | Cancer Res2002，62，15： | 1 |
| 20 | Hemorrhagic Fever with Renal Syndrome:Diagnostic problems with a known disease显示文摘 | Dominic W Werner S Peter A | 2001 | J Clin Microbiol2001，39，9： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员