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| 1 | Relationship between Th17 immune response and cancer显示文摘Cancer is the second leading cause of death worldwide and epidemiological projections predict growing cancer mortality rates in the next decades.Cancer has a close relationship with the immune system and,although Th17 cells are known to play roles in the immune response against microorganisms and in autoimmunity,studies have emphasized their roles in cancer pathogenesis.The Th17 immune response profile is involved in several types of cancer including urogenital,respiratory,gastrointestinal,and skin cancers.This type of immune response exerts pro and antitumor functions through several mechanisms,depending on the context of each tumor,including the protumor angiogenesis and exhaustion of T cells and the antitumor recruitment of T cells and neutrophils to the tumor microenvironment.Among other factors,the paradoxical behavior of Th17 cells in this setting has been attributed to its plasticity potential,which makes possible their conversion into other types of T cells such as Th17/Treg and Th17/Th1 cells.Interleukin(IL)-17 stands out among Th17-related cytokines since it modulates pathways and interacts with other cell profiles in the tumor microenvironment,which allow Th17 cells to prevail in tumors.Moreover,the IL-17 is able to mediate pro and antitumor processes that influence the development and progression of various cancers,being associated with variable clinical outcomes.The understanding of the relationship between the Th17 immune response and cancer as well as the singularities of carcinogenic processes in each type of tumor is crucial for the identification of new therapeutic targets. | Hanna Santos Marques Breno Bittencourt de Brito Filipe Antônio França da Silva Maria Luísa Cordeiro Santos Júlio César Braga de Souza Thiago Macêdo Lopes Correia Luana Weber Lopes Nayara Silva de Macêdo Neres Rafael Santos Dantas Miranda Dórea Anna Carolina Saúde Dantas Lorena Lôbo Brito Morbeck Iasmin Souza Lima Amanda Alves de Almeida Maiara Raulina de Jesus Dias Fabrício Freire de Melo | 2021 | World Journal of Clinical Oncology2021，12，10： | 5 |
| 2 | Cutting edge:dendritic cells are essential for in vim IL-12 production and development of resistance against Toxoplasma gondii infection in mice显示文摘 | Liu C H Fan Y T Dias A | 2006 | J Immunol2006，177，： | 1 |
| 3 | Rapid silver staining and recover of PCR products separated in polyacrylamide gels显示文摘 | SANGUINETTI C J DIAS N E SIMPSON A J G | 1994 | Bio techniques1994，17，： | 1 |
| 4 | 术中脑组织氧分压偏低与动脉瘤性蛛网膜下腔出血术后血管痉挛相关(英文)显示文摘Background Vasospasm is a frequent complication of subarachnoid hemorrhage ( SAH) ,implicated in poor outcome,and prediction of its occurrence might be important on the therapeutic approach of this condition. Brain oxygenation in aneurysmal SAH was prospectively monitored during surgery in 28 patients,using brain tissue oxygen pressure ( PbtO 2 ) ,studying its association with the occurrence of post-operative vasospasm,detected by transcranial Doppler. Methods PbtO 2 monitoring was performed during surgery of 28 patients with aneurysmal SAH,using a polarographic microcatheter ( Licox; GMS,Kiel,Germany) ,inserted into the cerebral tissue. The aneurysms were localized in the anterior communicating artery ( AcoA) complex ( eight cases) ,in the posterior communicating artery ( Pcom) origin ( seven cases) ,and in the middle cerebral artery ( MCA) bifurcation ( 13 cases) . Basal PbtO 2 values,obtained immediately before application of temporary or definitive clips,were studied according to age,clinical status and CT findings. The association between the basal values and the occurrence of increased blood flow velocity in the post-operative transcranial Doppler ( TCD vasospasm) was investigated. Results Post-operative TCD vasospasm developed in 13 patients,all of them with basal values inferior to 10 mmHg. PbtO 2 basal value was significantly lower in cases that developed TCD vasospasm. This association was independent of age, clinical status,or CT findings. Conclusion The finding of low intraoperative basal PbtO 2 values may be an indicator for a high risk of occurrence of post-operative TCD vasospasm in cases of aneurysmatic SAH. | Cerejo A Silva PA Vilarinho A Dias C Vaz R | 2012 | 中华神经外科疾病研究杂志2012，11，5： | 1 |
| 5 | Gastric juice prostaglandins and peptide growth factors as potential markers of chronic atrophic gastritis, intestinal metaplasia and gastric cancer: their potential clinical implications based on this pilot study 显示文摘 | Dias A Garcia C Majewski M | 2011 | Dig Dis Sci2011，56，11： | 1 |
| 6 | Rapid silver staining and recovery of PCR products separated on polyacrylamide gels 显示文摘 | SANGUINETTI C J DIAS NETO E SIMPSON A J | 1994 | Biotechniques1994，17，5： | 1 |
| 7 | Rapid silverstaining and recover of PCR products separated on polycrylamidegels显示文摘 | SANGUINETTI C J DIAS NETO E SIMPSON A J | 1994 | Biotechniques1994，17，5： | 1 |
| 8 | Improving elms performance under drought stress: The pretreatment with abscisic acid显示文摘 | Dias M C Oliveira H Costa A | 2014 | Environmental and Experimental Botany2014，100，： | 1 |
| 9 | Halo nevi association in nonsegmental vitiligo affects age at onset and depigmentation pattern 显示文摘 | Ezzedine K Dia]lo A Laut6-Labrze C | 2012 | Arch Dermatol2012，148，4： | 1 |
| 10 | 显示文摘 | Silva T F Dias J A C Maciel C G | 2013 | Catal Sci Technol2013，3，： | 1 |
| 11 | Rapid silver staining and recovery of PCR products separated on polyacrylamide gels polymerase chain reaction product recover显示文摘 | Sanguinetti C J Dias N E Simpson A J | 1994 | Biotechniques1994，17，5： | 1 |
| 12 | 显示文摘 | Pavan F A Dias S L P Lima E C | 2008 | Dyes Pigments2008，76，： | 1 |
| 13 | Risk factors associated with sero-positivity to Toxoplasma gondii in captive neotropical felids from Brazil显示文摘 | Ramossilva J C Marvulo M F Dias R A | 2007 | Prey Vet Med2007，78，34： | 1 |
| 14 | Immobilization of Fe, Mn and Co tetraphenylporphyrin complexes in MCM-41 and their catalytic activity in cyclohexene oxidation reaction by hydrogen peroxide 显示文摘 | COSTA A A GHESTI G F MACEDO J L BRAGA V S SANTOS M M DIAS J A DIAS S C L | 2008 | J Mol Catal A: Chem2008，282，： | 1 |
| 15 | Measurement of Host-to-Activator Transfer Efficiency in Nano-Crystalline Y2 03:Eu3 + under VUV Excitation显示文摘 | Waite C Mann R Dias A L | 2013 | Journal of Solid State Chemistry2013，198，： | 1 |
| 16 | Developments in a model to describe lowfrequency electrical polarization of rocks显示文摘 | Dias C A | 2000 | Geophysics2000，65，2： | 1 |
| 17 | Antisense Oligonucleotides:basic concepts and mechanisms显示文摘 | DIAS N STEIN C A | 2002 | Mol Cancer Ther2002，1，： | 1 |
| 18 | Autothermal reforming of methane over Ni/r-Al2O3 catalysts: the enhancement effect of small quantities of noble metals显示文摘 | Dias J A C Assaf J M | 2004 | Journal of Power Sources2004，130，12： | 1 |
| 19 | Cytogenetic analysis of spontaneously activated noninseminated oocytes and parthenogene -tically activated failed fertilized human oocytes -implications for the use of primate parthenotes for stem cell production显示文摘 | SANTOS T A DIAS C HENNIQUES P | 2003 | J Assist Reprod Genet2003，20，3： | 1 |
| 20 | Rapid silver staining and recovery of PCR products separated on polyacrylamide gels显示文摘 | Sanguinetti C J Dias Neto E Simpson A J | 1994 | Biotechniques1994，17，5： | 1 |
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