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| 1 | Protective effect of Nigella sativa oil against binge ethanolinduced oxidative stress and liver injury in rats显示文摘AIM: Nigella sativa L.(Ranunculaceae) is considered as a therapeutic plant-based medicine for liver damage. In this study, the aim was to study the effect of Nigella sativa oil(NSO) pretreatment on ethanol-induced hepatotoxicity in rats. METHOD: Rats were given Nigella sativa oil at doses of 2.5 and 5.0 mL·kg-1, orally for 3 weeks, followed by oral ethanol(EtOH) administration(5 g·kg-1) every 12 h three times(binge model). RESULTS: Binge ethanol application caused significant increases in plasma transaminase activities and hepatic triglyceride and malondialdehyde(MDA) levels. It decreased hepatic glutathione(GSH) levels, but did not change vitamins E and vitamin C levels and antioxidant enzyme activities. NSO(5.0 mL·kg-1) pretreatment significantly decreased plasma transaminase activities, hepatic MDA, and triglyceride levels together with amelioration in hepatic histopathological findings. CONCLUSION: NSO pretreatment may be effective in protecting oxidative stress-induced hepatotoxicity after ethanol administration. | Seval Develi Betül Evran Esra Betül Kalaz Necla Koak-Toker Gül zdemirler Erata | 2014 | Chinese Journal of Natural Medicines2014，12，7： | 4 |
| 2 | A High-toughness γ-titanium aluminides 显示文摘 | DEVE H E EVANS A G SHIH D S | 1992 | Acta Metall Mater1992，40，6： | 1 |
| 3 | High-resolution mapping of uranium and other trace elements in recrystallized aragonitecalcite speleothems from caves in the Pyrenees (France): Implication for U-series dating 显示文摘 | Ortega R Maire R Deves G Quinif Y | 2005 | Earth Planet Sci Lett2005，237，34： | 1 |
| 4 | Subcellular mass deter- mination by He^+ energy-loss microspectrometry显示文摘 | DEVES G ORTEGA R | 2002 | Analytical and Bioanalytical Chemistry2002，374，7： | 1 |
| 5 | Calcium, potassium, iron, copper and zinc concentrations in the white and gray matter of the cerebellum and corpus callosum in brain of four genetic mouse strains显示文摘 | SERGEANT C VESVRES M H DEVES G | 2005 | Nucl Instrum Methods Phys Res2005，231，14： | 1 |
| 6 | The impact of soy based biodiesel on PAH, nitro-PAH and oxy PAH emissions from a passenger car operated over regulated and nonregulated driving cycles显示文摘 | Karavalakls G Deves G Eontaras G | 2010 | Fuel2010，89，12： | 1 |
| 7 | Image reconstruc- tion with fraunhofer holograms 显示文摘 | DEVELIS J PARRENT G THOMPSON B | 1966 | Journal of the Optical Socie- ty of America1966，56，42： | 1 |
| 8 | Paparamborde: a software dedicated to quantitative mapping of biological samples using scanning transmission ion microscopy显示文摘 | Deve's G Michelet-Habchi C Ortega R | 2005 | Nuclr lnstr and Meth Ph ys Res B2005，231，： | 1 |
| 9 | Micro-chemical imaging of cesium distribution in Arabidopsis thaliana plant and its interaction with potassium and essential trace elements显示文摘 | ISAURE M FRAYSSE A DEVES G | 2006 | Biochimie2006，88，11： | 1 |
| 10 | A High - toughness γ - Titanium Aluminides显示文摘 | A G Evans D S Shih | 1992 | Acta Metall Mater1992，，： | 1 |
| 11 | Ductile reinforcement tughening and gamma-TiAl:effects of debonding and ductility显示文摘 | DEVE H E EVANS A G ODETTE G R | 1990 | Acta Metall Mater1990，38，8： | 1 |
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