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| 1 | Helicobacter pylori infection in bleeding peptic ulcer patients after non-steroidal antiinflammatory drug consumption显示文摘AIM:To establish the prevalence of Helicobacter pylori (H. pylori ) infection in patients with a bleeding peptic ulcer after consumption of non-steroidal antiinflamma- tory drugs (NSAIDs). METHODS:A very early upper endoscopy was performed to find the source of upper gastrointestinal bleeding and to take biopsy specimens for analysis of H. pylori infection by the rapid urease (CLO) test, histological examination, and bacterial culture. IgG anti-CagA were also sought. The gold standard for identifying H. pylori infection was positive culture of biopsy specimens or contemporary positivity of the CLO test and the presence of H. pylori on tissue sections. RESULTS:Eighty patients, 61 males (76.3%), mean age 61.2 ± 15.9 years, were consecutively enrolled. Forty-seven (58.8%) patients occasionally consumed NSAIDs, while 33 (41.3%) were on chronic treatment with low-dose aspirin (LD ASA). Forty-four (55.0%) patients were considered infected by H. pylori . The infection rate was not different between patients who occasionally or chronically consumed NSAIDs. The culture of biopsy specimens had a sensitivity of 86.4% and a specificity of 100%; corresponding figures for histological analysis were 65.9% and 77.8%, for the CLO test were 68.2% and 75%, for the combined use of histology and the CLO test were 56.8% and 100%, and for IgG anti-CagA were 90% and 98%. The highest accuracy (92.5%) was obtained with the culture of biopsy specimens.CONCLUSION:Patients with a bleeding peptic ulcer after NSAID/LD ASA consumption frequently have H. pylori infection. Biopsy specimen culture after an early upper gastrointestinal tract endoscopy seems the most efficient test to detect this infection. | Francesco Manguso Elisabetta Riccio Germana de Nucci Maria Luisa Aiezza Gerardino Amato Linda Degl'Innocenti Maria Maddalena Piccirillo Gianfranco De Dominicis Tara Santoro Elena Trimarco Antonio Balzano | 2011 | World Journal of Gastroenterology2011，17，40： | 4 |
| 2 | Cyclooxygenase-2 (COX-2) overexpression in meningiomas: real time PCR and immunohistochemistry显示文摘 | Buccoliero AM Castiglione F Rossi Degl'Innocenti D | 2007 | Appl Immunohistochem Mol Morphol2007，15，2： | 1 |
| 3 | Thermodynamical properties of unresolved magnetic flux tubes显示文摘 | Egidio Landi Degl’Innocenti Marco Landolfi | 1982 | Solar Physics (-)1982，，1： | 1 |
| 4 | Effect of root- stocks and harvesting time on the nutritional quality of peel and flesh of peach fruits显示文摘 | Remorini D Tavarini S Degl'Innocenti E | 2008 | Food Chemistry2008，110，： | 1 |
| 5 | Comparison of two different time interval protocols for central venous catheter dressing in bone marrow transplant patients 显示文摘 | Rasero L Degl'lnnocetl M Mocali M | 2000 | Haematologica2000，85，： | 1 |
| 6 | Effects of peritoneal effluents on mesothelial cells in culture: cell proliferation and extracellular matrix regulation显示文摘 | Perfumo F Altieri P Degl'Innocenti ML | 1996 | Nephrol Dial Transplant1996，11，9： | 1 |
| 7 | Y chromosome and male infer- tility: update, 2006 显示文摘 | Krausz C Degl'Innocenti S | 2006 | Front Biosci2006，11，： | 1 |
| 8 | Peripheral T-cell tolerance associated with prostate cancer is independent from CD4+CD25+ regulatory T cells显示文摘 | Degl'Innocenti E Grioni M Capuano G | 2008 | Cancer Res2008，68，1： | 1 |
| 9 | Low-bias terahertz amplitude modulator based on split-ring resona- tors and graphene 显示文摘 | DEGL'INNOCENTI R JESSOP D S SHAH Y D | 2014 | ACS Nano2014，8，3： | 1 |
| 10 | Peripheral T-cell tolerance associated with prostate cancer is independent from CD4^+ CD25^+ regulatory T cells显示文摘 | Degl' Innocenti E Grioni M Capuano G Jachetti E Fresehi M Bertilaccio M T | 2008 | Cancer Res2008，68，： | 1 |
| 11 | Growth characteristics of Rhodopseudomonas palustris cultured outdoors,in an underwater tubular photobioreactor,and investigation on photosynthetic efficiency显示文摘 | PIETRO CARLOZZI BENJAMIN PUSHPARAJ ALESSANDRO DEGL'INNOCENTI et d | 2006 | Appl Microbiol Biotechnol2006，73，4： | 1 |
| 12 | Physiological basis of sensitivity to enzymatic browning in 'lettuce', 'escarole' and 'rocket salad' when stored as fresh-cut products显示文摘 | DEGL'INNOCENTI E PARDOSSI A TOGNONI F | 2007 | Food Chemistry2007，104，1： | 1 |
| 13 | Bioactive compounds duing storage of fresh-cut spinach: The role of endogenous ascorbic acid in the improvement of product quality 显示文摘 | BOTTINO A DEGL INNOCENTI E GUIDI L | 2009 | Agric Food Chem2009，57，7： | 1 |
| 14 | Y chromosome and male infertility:update显示文摘 | Krausz C Degl' Innocenti S | 2006 | Front Biosci2006，11，： | 1 |
| 15 | Ozone effects on carbon metabolism in sensitive and insensitive Phaseolus cultivars显示文摘 | Guidi L Degl'Innocenti E Martinelli F | 2009 | Environmental and Experimental Botany2009，66，： | 1 |
| 16 | Comparison of two Different Time Interval Protocols for Central Venous Cather Dressing in Bone Marrow Transplant Patients:results of a Randomized,Multicenter Tudy显示文摘 | Rasero L Degl Innocenti M | 2000 | Haemato-logica2000，85，： | 1 |
| 17 | Antioxidant capacity,ascorbic acid, total phenols and carotenoids changes during harvest and after storage ofH hayward kiwifruit显示文摘 | Silvia Tavarini Elena Degl Damiana Amorini | 2008 | Food Chemistry2008，107，： | 1 |
| 18 | Polygalacturo- nase and -galactosidase activities in Hayward kiwifruit as affect- ed by light exposure, maturity stage and storage time 显示文摘 | Tavarinia S Degl'Innoeentia E Remorini D | 2009 | Sci Hor- tic2009，120，3： | 1 |
| 19 | The tight relation- ship between papillary thyroid cancer, autoimmunity and inflamma- tion: clinical and molecular studies 显示文摘 | Muzza M Degl'Innocenti D Colombo C | 2010 | Clin Endocrinol ( Oxf)2010，72，5： | 1 |
| 20 | Effects of NaCl or Na2SO4 salinity on plant growth, ion content and photosynthetic activity in Ocimum basilicum K 显示文摘 | Tarchoune I Degl' Innocenti E Kaddour R | 2012 | Acta Physiologiae Plantarum2012，34，2： | 1 |
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